Conserved proteins are fragile

Molecular Biology and Evolution

Volumn 31, Issue 2, 2014, Pages 419-424

  Assis, Raquel ^a   Kondrashov, Alexey S ^b  

^a PENNSYLVANIA STATE UNIVERSITY   (United States)

^b UNIVERSITY OF MICHIGAN   (United States)

Author keywords

evolutionary rate; natural selection; protein essentiality; protein evolution; selective constraint

Indexed keywords

PROTEIN;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMAL TISSUE; ARTICLE; CODON; EVOLUTIONARY RATE; EXON; FEMALE; GENE EXPRESSION; GENE FREQUENCY; MALE; MISSENSE MUTATION; MOLECULAR EVOLUTION; NONHUMAN; NONSENSE MUTATION; PROTEIN PROTEIN INTERACTION; TISSUE SPECIFICITY;

EVOLUTIONARY RATE; NATURAL SELECTION; PROTEIN ESSENTIALITY; PROTEIN EVOLUTION; SELECTIVE CONSTRAINT;

AMINO ACID SEQUENCE; AMINO ACIDS; ANIMALS; BIOLOGICAL EVOLUTION; CODON, NONSENSE; CONSERVED SEQUENCE; DROSOPHILA; EVOLUTION, MOLECULAR; FEMALE; GENE EXPRESSION PROFILING; GENETIC VARIATION; MALE; MODELS, GENETIC; MUTATION, MISSENSE; ORGAN SPECIFICITY; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEINS; SELECTION, GENETIC;

EID: 84893030090     PISSN: 07374038     EISSN: 15371719     Source Type: Journal    
DOI: 10.1093/molbev/mst217     Document Type: Article

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