Anti-infective and cytotoxic properties of Bupleurum marginatum

Chinese Medicine (United Kingdom)

Volumn 9, Issue 1, 2014, Pages

  Ashour, Mohamed L ^a,b   El Readi, Mahmoud Z ^a,c   Hamoud, Razan ^a   Eid, Safaa Y ^a   El Ahmady, Sherweit H ^b   Nibret, Endalkachew ^a   Herrmann, Florian ^a   Youns, Mahmoud ^d,e   Tahrani, Ahmed ^a   Kaufmann, Dorothea ^a   Wink, Michael ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b African Union Organization St Abbassia   (Egypt)

^c Al Azhar University   (Egypt)

^d GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^e Helwan   (Egypt)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFECTIVE AGENT; ANTITRYPANOSOMAL AGENT; BUPLEURUM MARGINATUM EXTRACT; CASPASE 3; CASPASE 7; DICHLOROMETHANE; FLAVONOID; LIGNAN; METHANOL; PLANT EXTRACT; PLANT MEDICINAL PRODUCT; RESAZURIN; UNCLASSIFIED DRUG;

AGAR DIFFUSION; ANIMAL CELL; ANTIMICROBIAL ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; ANTITRYPANOSOMAL ACTIVITY; ANTIVIRAL ACTIVITY; APOPTOSIS; ARTICLE; BROTH DILUTION; BUPLEURUM; BUPLEURUM MARGINATUM; CANCER CELL CULTURE; CANCER INHIBITION; CELL PROLIFERATION ASSAY; CELL STRAIN CACO 2; CELL STRAIN CCL 81; CELL STRAIN CCRF CEM; CELL STRAIN COS7; CELL STRAIN HL 60; CELL STRAIN MCF 7; CELL STRAIN MIA PACA 2; CELL STRAIN PANC 1; CONTROLLED STUDY; CYTOTOXICITY; GROWTH INHIBITION; HEPATITIS A VIRUS; HUMAN; HUMAN CELL; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MINIMUM INHIBITORY CONCENTRATION; MTT ASSAY; NONHUMAN; STREPTOCOCCUS PYOGENES; TRYPANOSOMA BRUCEI;

EID: 84892982169     PISSN: None     EISSN: 17498546     Source Type: Journal    
DOI: 10.1186/1749-8546-9-4     Document Type: Article

References (52)

1. Cordell GA. Natural products in drug discovery - Creating a new vision. Phytochem Rev 2002, 1:261-273.
2. Yaniv Z, Bachrach U. Handbook of medicinal plants 2005, New York: Food Products Press: Haworth Medical Press.
3. Mabberley DJ. Mabberley's plant-book: a portable dictionary of plants, their classification and uses. 3rd edn. Cambridge, UK 2008, New York: Cambridge University Press.
4. Pan S-L. Bupleurum species: scientific evaluation and clinical applications 2006, Boca Raton: CRC/Taylor & Francis.
5. World Health Organization WHO Monographs on Selected Medicinal Plants Vol 1 1999, Geneva: World Health Organization, World Health Organization.
6. Ashour ML, Wink M. Genus Bupleurum: a review of its phytochemistry, pharmacology and modes of action. J Pharm Pharmacol 2011, 63:305-321. 10.1111/j.2042-7158.2010.01170.x, 21749378.
7. Wu J-N. An illustrated Chinese materia medica 2005, New York: Oxford University Press.
8. Fundukian LJ. The Gale encyclopedia of alternative medicine 2009, Gale, Cengage Learning: Detroit, 3.
9. Zhou J. Encyclopedia of traditional Chinese medicines vol 1 - molecular structures, pharmacological activities, natural sources and applications 2011, New York: Springer.
10. Huang HQ, Zhang X, Lin M, Shen YH, Yan SK, Zhang WD. Characterization and identification of saikosaponins in crude extracts from three Bupleurum species using LC-ESI-MS. J Sep Sci 2008, 31:3190-3201. 10.1002/jssc.200800120, 18763253.
11. Ashour ML, El-Readi MZ, Tahrani A, Eid SY, Wink M. A novel cytotoxic aryltetraline lactone from Bupleurum marginatum (Apiaceae). Phytochem Lett 2012, 5:387-392.
12. Zhitao L, Minjian Q, Zhengtao W. Study on the constituent s of the roots of Bupleurum Marginatum. J China Pharmaceut Uni 2003, 34:305-308. [In Chinese].
13. Liu Y, Zhang T-T, Zhou J-S, Wang Q. Three new arylnaphthalide lignans from the aerial parts of Bupleurum marginatum WALL. ex DC. Helv Chim Acta 2008, 91:2316-2320.
14. Ashour ML, El-Readi M, Youns M, Mulyaningsih S, Sporer F, Efferth T, Wink M. Chemical composition and biological activity of the essential oil obtained from Bupleurum marginatum (Apiaceae). J Pharm Pharmacol 2009, 61:1079-1087.
15. Hamdan D, El-Readi MZ, Tahrani A, Herrmann F, Kaufmann D, Farrag N, El-Shazly A, Wink M. Chemical composition and biological activity of Citrus jambhiri Lush. Food Chem 2011, 127:394-403. 10.1016/j.foodchem.2010.12.129, 23140678.
16. Nibret E, Ashour ML, Rubanza CD, Wink M. Screening of some Tanzanian medicinal plants for their trypanocidal and cytotoxic activities. Phytother Res 2010, 24:945-947.
17. Huber W, Koella JC. A comparison of three methods of estimating EC50 in studies of drug resistance of malaria parasites. Acta Trop 1993, 55:257-261. 10.1016/0001-706X(93)90083-N, 8147282.
18. Nibret E, Sporer F, Asres K, Wink M. Antitrypanosomal and cytotoxic activities of pyrrolizidine alkaloid-producing plants of Ethiopia. J Pharm Pharmacol 2009, 61:801-808. 10.1211/jpp.61.06.0014, 19505372.
19. Mulyaningsih S, Sporer F, Reichling J, Wink M. Antibacterial activity of essential oils from Eucalyptus and of selected components against multidrug-resistant bacterial pathogens. Pharm Biol 2011, 49:893-899. 10.3109/13880209.2011.553625, 21591991.
20. Abou-Karam M, Shier WT. A simplified plaque reduction assay for antiviral agents from plants. Demonstration of frequent occurrence of antiviral activity in higher plants. J Nat Prod 1990, 53:340-344. 10.1021/np50068a011, 2166135.
21. Mosmann T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods 1983, 65:55-63. 10.1016/0022-1759(83)90303-4, 6606682.
22. Reimer TA, Anagnostopoulos I, Erdmann B, Lehmann I, Stein H, Daniel P, Dorken B, Rehm A. Reevaluation of the 22-1-1 antibody and its putative antigen, EBAG9/RCAS1, as a tumor marker. BMC Cancer 2005, 5:47. 10.1186/1471-2407-5-47, 1164403, 15904507.
23. Tasdemir D, Kaiser M, Brun R, Yardley V, Schmidt TJ, Tosun F, Ruedi P. Antitrypanosomal and antileishmanial activities of flavonoids and their analogues: in vitro, in vivo, structure-activity relationship, and quantitative structure-activity relationship studies. Antimicrob Agents Chemother 2006, 50:1352-1364. 10.1128/AAC.50.4.1352-1364.2006, 1426963, 16569852.
24. Wink M. Medicinal plants: source of anti-parasitic secondary metabolites. Molecules 2012, 17:12771-12791. 10.3390/molecules171112771, 23114614.
25. Mamadalieva NZ, Herrmann F, El-Readi MZ, Tahrani A, Hamoud R, Egamberdieva DR, Azimova SS, Wink M. Flavonoids in Scutellaria immaculata and S. ramosissima (Lamiaceae) and their biological activity. J Pharm Pharmacol 2011, 63:1346-1357. 10.1111/j.2042-7158.2011.01336.x, 21899551.
26. Hoet S, Opperdoes F, Brun R, Quetin-Leclercq J. Natural products active against African trypanosomes: a step towards new drugs. Nat Prod Rep 2004, 21:353-364. 10.1039/b311021b, 15162223.
27. Gertsch J, Tobler RT, Brun R, Sticher O, Heilmann J. Antifungal, antiprotozoal, cytotoxic and piscicidal properties of Justicidin B and a new arylnaphthalide lignan from Phyllanthus piscatorum. Planta Med 2003, 69:420-424.
28. Wink M. Evolutionary advantage and molecular modes of action of multi-component mixtures used in phytomedicine. Curr Drug Metab 2008, 9:996-1009. 10.2174/138920008786927794, 19075616.
29. Ushio Y, Abe H. Inactivation of measles virus and herpes simplex virus by saikosaponin d. Planta Med 1992, 58:171-173. 10.1055/s-2006-961422, 1529029.
30. Chiang LC, Ng LT, Liu LT, Shieh DE, Lin CC. Cytotoxicity and anti-hepatitis B virus activities of saikosaponins from Bupleurum species. Planta Med 2003, 69:705-709.
31. Cheng PW, Chiang LC, Yen MH, Lin CC. Bupleurum kaoi inhibits Coxsackie B virus type 1 infection of CCFS-1 cells by induction of type I interferons expression. Food Chem Toxicol 2007, 45:24-31. 10.1016/j.fct.2006.06.007, 17052829.
32. Charlton JL. Antiviral activity of lignans. J Nat Prod 1998, 61:1447-1451. 10.1021/np980136z, 9834179.
33. Wink M, Van Wyk B-E. Mind-altering and poisonous plants of the world 2008, Portland: Timber Press.
34. Bedows E, Hatfield GM. An investigation of the antiviral activity of Podophyllum peltatum. J Nat Prod 1982, 45:725-729. 10.1021/np50024a015, 6298369.
35. MacRae WD, Hudson JB, Towers GH. The antiviral action of lignans. Planta Med 1989, 55:531-535. 10.1055/s-2006-962087, 2559420.
36. Jassim SA, Naji MA. Novel antiviral agents: a medicinal plant perspective. Appl Microbiol 2003, 95:412-427.
37. Cushnie TP, Lamb AJ. Antimicrobial activity of flavonoids. Int J Antimicrob Agents 2005, 26:343-356. 10.1016/j.ijantimicag.2005.09.002, 16323269.
38. Naithani R, Huma LC, Holland LE, Shukla D, McCormick DL, Mehta RG, Moriarty RM. Antiviral activity of phytochemicals: a comprehensive review. Mini-Rev Med Chem 2008, 8:1106-1133.
39. Kaul TN, Middleton E, Ogra PL. Antiviral effect of flavonoids on human viruses. J Med Virol 1985, 15:71-79. 10.1002/jmv.1890150110, 2981979.
40. Ohnishi E, Bannai H. Quercetin potentiates TNF-induced antiviral activity. Antiviral Res 1993, 22:327-331. 10.1016/0166-3542(93)90041-G, 8279819.
41. Kim HJ, Woo ER, Shin CG, Park H. A new flavonol glycoside gallate ester from Acer okamotoanum and its inhibitory activity against human immunodeficiency virus-1 (HIV-1) integrase. J Nat Prod 1998, 61:145-148. 10.1021/np970171q, 9461665.
42. Hsu YL, Kuo PL, Weng TC, Yen MH, Chiang LC, Lin CC. The antiproliferative activity of saponin-enriched fraction from Bupleurum Kaoi is through Fas-dependent apoptotic pathway in human non-small cell lung cancer A549 cells. Biol Pharm Bull 2004, 27:1112-1115. 10.1248/bpb.27.1112, 15256750.
43. Cheng YL, Lee SC, Lin SZ, Chang WL, Chen YL, Tsai NM, Liu YC, Tzao C, Yu DS, Harn HJ. Anti-proliferative activity of Bupleurum scrozonerifolium in A549 human lung cancer cells in vitro and in vivo. Cancer Lett 2005, 222:183-193. 10.1016/j.canlet.2004.10.015, 15863267.
44. Fujioka T, Yoshida K, Shibao H, Nagao T, Yoshida M, Matsunaga K, Takata J, Karube Y, Iwase Y, Okabe H, Mihashi K. Antiproliferative constituents from umbelliferae plants. IX. New triterpenoid glycosides from the fruits of Bupleurum rotundifolium. Chem Pharm Bull 2006, 54:1694-1704. 10.1248/cpb.54.1694, 17139105.
45. Chen YL, Lin SZ, Chang WL, Cheng YL, Harn HJ. Requirement for ERK activation in acetone extract identified from Bupleurum scorzonerifolium induced A549 tumor cell apoptosis and keratin 8 phosphorylation. Life Sci 2005, 76:2409-2420. 10.1016/j.lfs.2004.09.044, 15763073.
46. Csokay B, Prajda N, Weber G, Olah E. Molecular mechanisms in the antiproliferative action of quercetin. Life Sci 1997, 60:2157-2163. 10.1016/S0024-3205(97)00230-0, 9188758.
47. Xavier CP, Lima CF, Preto A, Seruca R, Fernandes-Ferreira M, Pereira-Wilson C. Luteolin, quercetin and ursolic acid are potent inhibitors of proliferation and inducers of apoptosis in both KRAS and BRAF mutated human colorectal cancer cells. Cancer Lett 2009, 281:162-170. 10.1016/j.canlet.2009.02.041, 19344998.
48. MacRae WD, Towers GHN. Biological activities of lignans. Phytochemistry 1984, 23:1207-1220.
49. Wink M. Plant secondary metabolism: diversity, function and its evolution. Nat Prod Commun 2008, 3:1205-1216.
50. Seithel A, Karlsson J, Hilgendorf C, Bjorquist A, Ungell AL. Variability in mRNA expression of ABC- and SLC-transporters in human intestinal cells: comparison between human segments and Caco-2 cells. Eur J Pharm Sci 2006, 28:291-299. 10.1016/j.ejps.2006.03.003, 16704924.
51. Wink M, Ashour ML, El-Readi MZ. Secondary metabolites from plants inhibiting ABC transporters and reversing resistance of cancer cells and microbes to cytotoxic and antimicrobial agents. Front Microbiol 2012, 3:130. 3332394, 22536197.
52. El-Readi MZ, Hamdan D, Farrag N, El-Shazly A, Wink M. Inhibition of P-glycoprotein activity by limonin and other secondary metabolites from Citrus species in human colon and leukaemia cell lines. Eur J Pharmacol 2010, 626:139-145. 10.1016/j.ejphar.2009.09.040, 19782062.