-
1
-
-
0037106275
-
Anticancer drug discovery and development throughout the world
-
G. Schwartsmann, M.J. Ratain, G.M. Cragg, J.E. Wong, N. Saijo, and D.R. Parkinson Anticancer drug discovery and development throughout the world J. Clin. Oncol. 20 2002 47S 59S
-
(2002)
J. Clin. Oncol.
, vol.20
-
-
Schwartsmann, G.1
Ratain, M.J.2
Cragg, G.M.3
Wong, J.E.4
Saijo, N.5
Parkinson, D.R.6
-
2
-
-
0037099609
-
Molecular effects of the herbal compound PC-SPES: Identification of activity pathways in prostate carcinoma
-
M. Bonham, H. Arnold, B. Montgomery, and P.S. Nelson Molecular effects of the herbal compound PC-SPES: identification of activity pathways in prostate carcinoma Cancer Res. 62 2002 3920 3924
-
(2002)
Cancer Res.
, vol.62
, pp. 3920-3924
-
-
Bonham, M.1
Arnold, H.2
Montgomery, B.3
Nelson, P.S.4
-
3
-
-
0037145720
-
Ganoderma lucidum extract induces cell cycle arrest and apoptosis in MCF-7 human breast cancer cell
-
H. Hu, N.S. Ahn, X. Yang, Y.S. Lee, and K.S. Kang Ganoderma lucidum extract induces cell cycle arrest and apoptosis in MCF-7 human breast cancer cell Int. J. Cancer 102 2002 250 253
-
(2002)
Int. J. Cancer
, vol.102
, pp. 250-253
-
-
Hu, H.1
Ahn, N.S.2
Yang, X.3
Lee, Y.S.4
Kang, K.S.5
-
4
-
-
0035902794
-
The Chinese medicine Bu-Zhong-Yi-Qi-Tang inhibited proliferation of hepatoma cell lines by inducing apoptosis via G0/G1 arrest
-
S.T. Kao, C.C. Yeh, C.C. Hsieh, M.D. Yang, M.R. Lee, and H.S. Liu The Chinese medicine Bu-Zhong-Yi-Qi-Tang inhibited proliferation of hepatoma cell lines by inducing apoptosis via G0/G1 arrest Life Sci. 69 2001 1485 1496
-
(2001)
Life Sci.
, vol.69
, pp. 1485-1496
-
-
Kao, S.T.1
Yeh, C.C.2
Hsieh, C.C.3
Yang, M.D.4
Lee, M.R.5
Liu, H.S.6
-
5
-
-
0036419057
-
Botanical medicines for the treatment of cancer: Rationale, overview of current data, and methodological considerations for phase I and II trials
-
A. Vickers Botanical medicines for the treatment of cancer: rationale, overview of current data, and methodological considerations for phase I and II trials Cancer Invest. 20 2002 1069 1079
-
(2002)
Cancer Invest.
, vol.20
, pp. 1069-1079
-
-
Vickers, A.1
-
6
-
-
0027972604
-
The herbal medicine sho-saiko-to inhibits proliferation of cancer cell lines by inducing apoptosis and arrest at the G0/G1 phase
-
H. Yano, A. Mizoguchi, K. Fukuda, M. Haramaki, S. Ogasawara, and S. Momosaki The herbal medicine sho-saiko-to inhibits proliferation of cancer cell lines by inducing apoptosis and arrest at the G0/G1 phase Cancer Res. 54 1994 448 454
-
(1994)
Cancer Res.
, vol.54
, pp. 448-454
-
-
Yano, H.1
Mizoguchi, A.2
Fukuda, K.3
Haramaki, M.4
Ogasawara, S.5
Momosaki, S.6
-
7
-
-
0033664246
-
Huanglian, a chinese herbal extract, inhibits cell growth by suppressing the expression of cyclin B1 and inhibiting CDC2 kinase activity in human cancer cells
-
X.K. Li, M. Motwani, W. Tong, W. Bornmann, and G.K. Schwartz Huanglian, a chinese herbal extract, inhibits cell growth by suppressing the expression of cyclin B1 and inhibiting CDC2 kinase activity in human cancer cells Mol. Pharmacol. 58 2000 1287 1293
-
(2000)
Mol. Pharmacol.
, vol.58
, pp. 1287-1293
-
-
Li, X.K.1
Motwani, M.2
Tong, W.3
Bornmann, W.4
Schwartz, G.K.5
-
8
-
-
0037183737
-
Paeoniae Radix, a Chinese herbal extract, inhibit hepatoma cells growth by inducing apoptosis in a p53 independent pathway
-
S.M. Lee, M.L. Li, Y.C. Tse, S.C. Leung, M.M. Lee, and S.K. Tsui Paeoniae Radix, a Chinese herbal extract, inhibit hepatoma cells growth by inducing apoptosis in a p53 independent pathway Life Sci. 71 2002 2267 2277
-
(2002)
Life Sci.
, vol.71
, pp. 2267-2277
-
-
Lee, S.M.1
Li, M.L.2
Tse, Y.C.3
Leung, S.C.4
Lee, M.M.5
Tsui, S.K.6
-
10
-
-
0042196008
-
Acetone extract of Bupleurum scorzonerifolium inhibits proliferation of A549 human lung cancer cells via inducing apoptosis and suppressing telomerase activity
-
Y.L. Cheng, W.L. Chang, S.C. Lee, Y.G. Liu, H.C. Lin, and C.J. Chen Acetone extract of Bupleurum scorzonerifolium inhibits proliferation of A549 human lung cancer cells via inducing apoptosis and suppressing telomerase activity Life Sci. 73 2003 2383 2394
-
(2003)
Life Sci.
, vol.73
, pp. 2383-2394
-
-
Cheng, Y.L.1
Chang, W.L.2
Lee, S.C.3
Liu, Y.G.4
Lin, H.C.5
Chen, C.J.6
-
11
-
-
0034125751
-
Establishment and characterization of renal cell carcinoma cell lines with multidrug resistance
-
D.S. Yu, C.P. Ma, and S.Y. Chang Establishment and characterization of renal cell carcinoma cell lines with multidrug resistance Urol. Res. 28 2000 86 92
-
(2000)
Urol. Res.
, vol.28
, pp. 86-92
-
-
Yu, D.S.1
Ma, C.P.2
Chang, S.Y.3
-
12
-
-
0029945204
-
A novel assay to measure loss of plasma membrane asymmetry during apoptosis of adherent cells in culture
-
M. van Engeland, F.C. Ramaekers, B. Schutte, and C.P. Reutelingsperger A novel assay to measure loss of plasma membrane asymmetry during apoptosis of adherent cells in culture Cytometry 24 1996 131 139
-
(1996)
Cytometry
, vol.24
, pp. 131-139
-
-
Van Engeland, M.1
Ramaekers, F.C.2
Schutte, B.3
Reutelingsperger, C.P.4
-
13
-
-
0037577193
-
CP248, a derivative of exisulind, causes growth inhibition, mitotic arrest, and abnormalities in microtubule polymerization in glioma cells
-
J.T. Yoon, A.F. Palazzo, D. Xiao, T.M. Delohery, P.E. Warburton, and J.N. Bruce CP248, a derivative of exisulind, causes growth inhibition, mitotic arrest, and abnormalities in microtubule polymerization in glioma cells Mol. Cancer Ther. 1 2002 393 404
-
(2002)
Mol. Cancer Ther.
, vol.1
, pp. 393-404
-
-
Yoon, J.T.1
Palazzo, A.F.2
Xiao, D.3
Delohery, T.M.4
Warburton, P.E.5
Bruce, J.N.6
-
14
-
-
12944277104
-
A common pharmacophore for epothilone and taxanes: Molecular basis for drug resistance conferred by tubulin mutations in human cancer cells
-
P. Giannakakou, R. Gussio, E. Nogales, K.H. Downing, D. Zaharevitz, and B. Bollbuck A common pharmacophore for epothilone and taxanes: molecular basis for drug resistance conferred by tubulin mutations in human cancer cells Proc. Natl Acad. Sci. USA 97 2000 2904 2909
-
(2000)
Proc. Natl Acad. Sci. USA
, vol.97
, pp. 2904-2909
-
-
Giannakakou, P.1
Gussio, R.2
Nogales, E.3
Downing, K.H.4
Zaharevitz, D.5
Bollbuck, B.6
-
15
-
-
0036898629
-
Pattern of antitumor activity of a novel camptothecin, ST1481, in a large panel of human tumor xenografts
-
G. Pratesi, M. de Cesare, N. Carenini, P. Perego, S.C. Righetti, and C. Cucco Pattern of antitumor activity of a novel camptothecin, ST1481, in a large panel of human tumor xenografts Clin. Cancer Res. 8 2002 3904 3909
-
(2002)
Clin. Cancer Res.
, vol.8
, pp. 3904-3909
-
-
Pratesi, G.1
De Cesare, M.2
Carenini, N.3
Perego, P.4
Righetti, S.C.5
Cucco, C.6
-
16
-
-
0033566690
-
Potent antitumor activity of MS-247, a novel DNA minor groove binder, evaluated by an in vitro and in vivo human cancer cell line panel
-
T. Yamori, A. Matsunaga, S. Sato, K. Yamazaki, A. Komi, and K. Ishizu Potent antitumor activity of MS-247, a novel DNA minor groove binder, evaluated by an in vitro and in vivo human cancer cell line panel Cancer Res. 59 1999 4042 4049
-
(1999)
Cancer Res.
, vol.59
, pp. 4042-4049
-
-
Yamori, T.1
Matsunaga, A.2
Sato, S.3
Yamazaki, K.4
Komi, A.5
Ishizu, K.6
-
17
-
-
0028916569
-
Relationships between DNA fragmentation, chromatin condensation, and changes in flow cytometry profiles detected during apoptosis
-
O. Tounekti, J. Belehradek Jr., and L.M. Mir Relationships between DNA fragmentation, chromatin condensation, and changes in flow cytometry profiles detected during apoptosis Exp. Cell Res. 217 1995 506 516
-
(1995)
Exp. Cell Res.
, vol.217
, pp. 506-516
-
-
Tounekti, O.1
Belehradek Jr., J.2
Mir, L.M.3
-
18
-
-
0033828987
-
Effector caspases are dispensable for the early nuclear morphological changes during chemical-induced apoptosis
-
V.L. Johnson, S.C. Ko, T.H. Holmstrom, J.E. Eriksson, and S.C. Chow Effector caspases are dispensable for the early nuclear morphological changes during chemical-induced apoptosis J. Cell Sci. 113 Pt 17 2000 2941 2953
-
(2000)
J. Cell Sci.
, vol.113
, Issue.17 PART
, pp. 2941-2953
-
-
Johnson, V.L.1
Ko, S.C.2
Holmstrom, T.H.3
Eriksson, J.E.4
Chow, S.C.5
-
19
-
-
0031985647
-
Annexin V-affinity assay: A review on an apoptosis detection system based on phosphatidylserine exposure
-
M. van Engeland, L.J. Nieland, F.C. Ramaekers, B. Schutte, and C.P. Reutelingsperger Annexin V-affinity assay: a review on an apoptosis detection system based on phosphatidylserine exposure Cytometry 31 1998 1 9
-
(1998)
Cytometry
, vol.31
, pp. 1-9
-
-
Van Engeland, M.1
Nieland, L.J.2
Ramaekers, F.C.3
Schutte, B.4
Reutelingsperger, C.P.5
-
20
-
-
0028890119
-
Apoptosis and cancer: The failure of controls on cell death and cell survival
-
S.J. Martin, and D.R. Green Apoptosis and cancer: the failure of controls on cell death and cell survival Crit Rev. Oncol. Hematol. 18 1995 137 153
-
(1995)
Crit Rev. Oncol. Hematol.
, vol.18
, pp. 137-153
-
-
Martin, S.J.1
Green, D.R.2
-
21
-
-
0346873049
-
Anticancer therapy targeting the apoptotic pathway
-
W. Hu, and J.J. Kavanagh Anticancer therapy targeting the apoptotic pathway Lancet Oncol. 4 2003 721 729
-
(2003)
Lancet Oncol.
, vol.4
, pp. 721-729
-
-
Hu, W.1
Kavanagh, J.J.2
-
22
-
-
0028800947
-
Early redistribution of plasma membrane phosphatidylserine is a general feature of apoptosis regardless of the initiating stimulus: Inhibition by overexpression of Bcl-2 and Abl
-
S.J. Martin, C.P. Reutelingsperger, A.J. McGahon, J.A. Rader, R.C. van Schie, and D.M. LaFace Early redistribution of plasma membrane phosphatidylserine is a general feature of apoptosis regardless of the initiating stimulus: inhibition by overexpression of Bcl-2 and Abl J. Exp. Med. 182 1995 1545 1556
-
(1995)
J. Exp. Med.
, vol.182
, pp. 1545-1556
-
-
Martin, S.J.1
Reutelingsperger, C.P.2
McGahon, A.J.3
Rader, J.A.4
Van Schie, R.C.5
Laface, D.M.6
-
24
-
-
0030702084
-
Caspases: Intracellular signaling by proteolysis
-
G.S. Salvesen, and V.M. Dixit Caspases: intracellular signaling by proteolysis Cell 91 1997 443 446
-
(1997)
Cell
, vol.91
, pp. 443-446
-
-
Salvesen, G.S.1
Dixit, V.M.2
-
25
-
-
0009530192
-
Human ICE/CED-3 protease nomenclature
-
E.S. Alnemri, D.J. Livingston, D.W. Nicholson, G. Salvesen, N.A. Thornberry, W.W. Wong, and J. Yuan Human ICE/CED-3 protease nomenclature Cell 87 1996 171
-
(1996)
Cell
, vol.87
, pp. 171
-
-
Alnemri, E.S.1
Livingston, D.J.2
Nicholson, D.W.3
Salvesen, G.4
Thornberry, N.A.5
Wong, W.W.6
Yuan, J.7
-
26
-
-
0037100740
-
Targeting the cell cycle for cancer therapy
-
A. Carnero Targeting the cell cycle for cancer therapy Br. J. Cancer 87 2002 129 133
-
(2002)
Br. J. Cancer
, vol.87
, pp. 129-133
-
-
Carnero, A.1
-
27
-
-
0034594624
-
Tubulin/microtubules: Still a promising target for new chemotherapeutic agents
-
P. Giannakakou, D. Sackett, and T. Fojo Tubulin/microtubules: still a promising target for new chemotherapeutic agents J. Natl Cancer Inst. 92 2000 182 183
-
(2000)
J. Natl Cancer Inst.
, vol.92
, pp. 182-183
-
-
Giannakakou, P.1
Sackett, D.2
Fojo, T.3
-
28
-
-
0032945092
-
Saikosaponins from roots of Bupleurum scorzonerifolium
-
L. Tan, Y. Zhao, G. Tu, B. Wang, S. Cai, and R. Zhang Saikosaponins from roots of Bupleurum scorzonerifolium Phytochemistry 50 1999 139 142
-
(1999)
Phytochemistry
, vol.50
, pp. 139-142
-
-
Tan, L.1
Zhao, Y.2
Tu, G.3
Wang, B.4
Cai, S.5
Zhang, R.6
-
29
-
-
0032555321
-
In vivo and in vitro antiinflammatory activity of saikosaponins
-
B.P. Bermejo, M.J. Abad Martinez, A.M. Silvan Sen, G.A. Sanz, M.L. Fernandez, C.S. Sanchez, and A.M. Diaz Lanza In vivo and in vitro antiinflammatory activity of saikosaponins Life Sci. 63 1998 1147 1156
-
(1998)
Life Sci.
, vol.63
, pp. 1147-1156
-
-
Bermejo, B.P.1
Abad Martinez, M.J.2
Silvan Sen, A.M.3
Sanz, G.A.4
Fernandez, M.L.5
Sanchez, C.S.6
Diaz Lanza, A.M.7
-
30
-
-
0036181495
-
Antiviral activity of seven iridoids, three saikosaponins and one phenylpropanoid glycoside extracted from Bupleurum rigidum and Scrophularia scorodonia
-
P. Bermejo, M.J. Abad, A.M. Diaz, L. Fernandez, J.D. Santos, and S. Sanchez Antiviral activity of seven iridoids, three saikosaponins and one phenylpropanoid glycoside extracted from Bupleurum rigidum and Scrophularia scorodonia Planta Med. 68 2002 106 110
-
(2002)
Planta Med.
, vol.68
, pp. 106-110
-
-
Bermejo, P.1
Abad, M.J.2
Diaz, A.M.3
Fernandez, L.4
Santos, J.D.5
Sanchez, S.6
-
31
-
-
0034211738
-
High-performance liquid chromatographic analysis of saponin compounds in Bupleurum falcatum
-
I.S. Park, E.M. Kang, and N. Kim High-performance liquid chromatographic analysis of saponin compounds in Bupleurum falcatum J. Chromatogr. Sci. 38 2000 229 233
-
(2000)
J. Chromatogr. Sci.
, vol.38
, pp. 229-233
-
-
Park, I.S.1
Kang, E.M.2
Kim, N.3
|