Requirement for ERK activation in acetone extract identified from Bupleurrum scorzonerifolium induced A549 tumor cell apoptosis and keratin 8 phosphorylation

Life Sciences

Volumn 76, Issue 21, 2005, Pages 2409-2420

  Chen, Yi Lin ^a   Lin, Shinn Zong ^a   Chang, Wen Liang ^b   Cheng, Yeung Leung ^c   Harn, Horng Jyh ^a  

^a TZU CHI UNIVERSITY   (Taiwan)

^b NATIONAL DEFENSE MEDICAL CENTER   (Taiwan)

^c TRI SERVICE GENERAL HOSPITAL   (Taiwan)

Author keywords

Acetone extract of Bupleurum scorzonerifolium (AE BS); Apoptosis; ERK1 2; Keratin 8 phosphorylation; Liquid chromatography tandem mass spectrometry; Two dimensional gel electrophoresis

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ACETONE; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; BUPLEURRUM SCORZONERIFOLIUM EXTRACT; KERATIN; KERATIN 8; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE P38 INHIBITOR; PLANT EXTRACT; SERINE; STRESS ACTIVATED PROTEIN KINASE INHIBITOR; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; BUPLEURRUM SCORZONERIFOLIUM; CANCER CELL; CONTROLLED STUDY; DRUG EFFECT; ENZYME ACTIVATION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; INCUBATION TIME; LIQUID CHROMATOGRAPHY; LUNG ADENOCARCINOMA; MEDICINAL PLANT; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN MODIFICATION; PROTEIN PHOSPHORYLATION; PROTEIN TARGETING; TANDEM MASS SPECTROMETRY; TWO DIMENSIONAL ELECTROPHORESIS;

BUPLEURUM SCORZONERIFOLIUM;

EID: 14844317349     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lfs.2004.09.044     Document Type: Article

References (32)

1. H.J. Baribault, R.V. Penner, K. Miyai, and R.G. Oshima Mid-gestational lethality in mice lacking keratin 8 Genes and Development 7 7A 1993 1191 1202
2. H.J. Baribault, R.V. Penner, and H.M. Wilson Colorectal hyperplasia and inflammation in keratin 8-deficiency FVB/N mice Genes and Development 8 24 1994 2964 2973
3. F.C. Brantley, C.S. Lyle, L. Du, M.E. Goodwin, and T. Hall The JNK, ERK and p53 pathway play distinct roles in apoptosis mediated by the antitumor agents vinblastine, doxorubicin, and etoposide Biochemical Pharmacology 66 3 2003 459 469
4. C. Caulin, C.F. Ware, T.M. Magin, and R.G. Oshima Keratin-dependent, epithelial resistant to tumor necrosis factor-induced apoptosis Journal of Cell Biology 149 1 2000 17 22
5. Chang, W.L., Cheng, Y.L., Lin, H.C., Lin, S.Z., Harn, H.J., submitted for publication. Novel lignans, isochaichulactone, suppresses proliferation of human taxol resistant cell line AT12 by inhibiting telomerase activity and upper regulation of p21 and p53 leading to apoptosis.
6. Y.L. Cheng, W.L. Chang, S.C. Lee, Y.G. Liu, H.C. Lin, C.J. Chen, C.Y. Yen, D.S. Yu, S.Z. Lin, and H.J. Harn Acetone extract of Bupleurum scorzonerifolium inhibits proliferation of A549 human lung cancer cells via inducing apoptosis and suppressing telomerase activity Life Sciences 73 18 2003 2383 2394
7. J. Chou, C.D. Chiang, C.S. Rao, W.M. Chang, and Y.K. Lai Establishment and chcracterization of paclitaxel-resistant human non-small cell lung cancer cell line Anticancer Research 20 4 2000 2449 2456
8. M. Fan, M.E. Goodwin, M.J. Birrer, and T.C. Chambers The c-jun NH(2)-terminal protein kinases/AP-1 pathwa is required for efficient apoptosis induced by vinblastine Cancer Research 61 11 2001 4450 4458
9. E. Fuchs, and D.W. Cleveland Intermediate filament: structure, dynamics, function, and disease Annual Review of Biochemistry 63 1994 345 382
10. E. Fuchs, and D.W. Cleveland A structural scaffolding of intermediate filaments in health and disease Science 279 5350 1998 514 519
11. S. Galbert, A. Loranger, N. Daigle, and N. Marceau Simple epithelium keratin 8 and 18 provide resistance to Fas-mediated apoptosis. The protection occurs through a receptor-targeting modulation Journal of Cell Biology 154 4 2001 763 773
12. T. He, A. Stepulak, T.H. Holmstrom, M.B. Omary, and J.E. Eriksson The intermediate filament protein keratin 8 is a novel cytoplasmic susbstrate for c-jun N-terminal kinase Journal of Biological Chemistry 277 13 2002 10767 10774
13. H. Inada, I. Izawa, M. Nishizawa, E. Fujita, and T. Kiyono Keratin attenuates tumor necrosis factor-induced cytotoxicity through association with TRADD Journal of Cell Biology 155 3 2001 415 425
14. S.T. Kao, C.C. Yeh, C.C. Hsieh, M.D. Yang, M.R. Lee, H.S. Liu, and J.G. Lin The Chinese medicine Bu-Zhong-Yi-Qi-Tang Inhibited proliferation of hepatoma cell liens by inducing apoptosis via G0/G1 arrest Life Sciences 69 13 2001 1485 1496
15. M. Kato, K.L. Isobe, Y. Dai, W. Liu, M. Takahashi, and K. Nakashima Further characterization of the Sho-saio-to mediated anti-tumor effect on melanoma developed in RET-transgenic mice The Journal of Investigative Dermatology 114 3 2000 599 601
16. N.O. Ku, J. Liao, C.F. Chou, and M.B. Omary Implications of intermediate filament protein phosphorylation Cancer Metastasis Review 15 4 1999 429 444
17. S. Kuster, G. Tiegs, L. Alexopoulou, E. Pasparakis, and M. Grell In vivo evidence for a functional role of both tumor necrosis factor (TNF) receptors and transmembrane TNF in experimental hepatitis European Journal of Immunology 27 11 1997 2870 2875
18. J. Liao, L.A. Lowthert, and M.B. Omary Heat stress or rotavirus infection of human epithelial cells generates a distinct hyperphosphorylated form of keratin 8 Experimental Cell Research 219 2 1995 348 357
19. J. Liao, N.O. Ku, and M.B. Omary Stress, apoptosis, and mitosis induce phosphorylation of human keratin 8 at Ser-73 in tissues and cultured cells Journal of Biological Chemistry 272 28 1997 17565 17573
20. J.H. Losa, C.P. Cobo, J.G. Viniegra, and P.R. Sanchez Role of the p38 MAPK pathway in cisplatin-based therapy Oncogene 22 26 2003 3998 4006
21. W.H. Mclean, and E.B. Lane Intermediate filaments in disease Current Opinion in Cell Biology 7 1 1995 118 125
22. R. Moll, W.W. Franke, F.C. Schiller, P.H. Krammer, and M.E. Peter The catalog of human cytokeratins: pattern of expression in normal epithelial, tumor and culture cells Cell 31 1 1982 11 24
23. K. Nam, S. Azhar, and M.B. Omary Keratin 8 phosphorylation by p38 kinase regulates cellular keratin filament reorganization Journal of Biological Chemistry 277 13 2002 10775 10782
24. J.I. Okano, and A.K. Rustgi Paclitaxel induced prolonged activation of the Ras/MEK/ERK pathway independent of activating the programmed cell cycle death machinery Journal of Biological Chemistry 276 22 2001 19555 19564
25. M.B. Omary, and N.O. Ku Intermediate filament proteins of the liver: emerging disease association and functions Hepatology 25 5 1997 1043 1048
26. R. Sedman, I. Gitelman, S.B. Horwitz, and M. Wolfson The role of ERK1/2 and p38 MAP-kinase pathways in taxol-induced apoptosis in human ovarian carcinoma cells Experimental Cell Research 268 1 2001 84 92
27. K. Subbaramaiah, J.C. Hart, L. Norton, and A.J. Dannenberg Microtubule-interfering agents stimulate the transcription of cyclooxygenase-2 Journal of Biological Chemistry 275 20 2000 14838 14845
28. D.M. Toivola, Q. Zhou, L.S. English, and M.B. Omary Type II keratins are phosphorylated on a unique motif during stress and mitosis in tissues and cultured cells Molecular Biology of the Cell 13 6 2002 1857 1870
29. P.M. Vilalta, L. Zhang, and S.F. Hamm-Alvarez A novel taxol-induced vimentin phosphorylation and stabilization revealed by studies on stable microtubules and vimentin intermediate filaments Journal of Cell Biology 111 13 1998 1841 1852
30. X. Wang, J.L. Martindale, and N.J. Holbrook Requirement for ERK activation in cisplatin-induced apoptosis Journal of Biological Chemistry 275 50 2000 39435 39443
31. C.H. Yang, and S.B. Horwitz Taxol mediates serine phosphorylation of the 66-Kd Shcisoform Cancer Research 60 18 2000 5171 5178
32. H. Yano, A. Mizoguchi, K. Fukuda, M. Haramaki, S. Ogasawara, S. Momosaki, and M. Kojiro The herbal medicine sho-saiko-to inhibits proliferation of cancer cell liens by inducing apoptosis and arrest at the Go/G1 phase Cancer Research 54 2 1994 448 454