-
1
-
-
30444437486
-
Treatment of acute lymphoblastic leukemia
-
DOI 10.1056/NEJMra052603
-
Pui CH, Evans WE: Treatment of acute lymphoblastic leukemia. N Engl J Med 354:166-178, 2006 (Pubitemid 43076714)
-
(2006)
New England Journal of Medicine
, vol.354
, Issue.2
, pp. 166-178
-
-
Pui, C.-H.1
Evans, W.E.2
-
2
-
-
42649124306
-
Molecular pathogenesis of T-cell leukaemia and lymphoma
-
DOI 10.1038/nri2304, PII NRI2304
-
Aifantis I, Raetz E, Buonamici S: Molecular pathogenesis of T-cell leukaemia and lymphoma. Nat Rev Immunol 8:380-390, 2008 (Pubitemid 351595220)
-
(2008)
Nature Reviews Immunology
, vol.8
, Issue.5
, pp. 380-390
-
-
Aifantis, I.1
Raetz, E.2
Buonamici, S.3
-
3
-
-
81055149624
-
Pediatric-inspired intensified therapy of adult T-ALL reveals the favorable outcome of NOTCH1/ FBXW7 mutations, but not of low ERG/BAALC expression: A GRAALL study
-
Ben Abdelali R, Asnafi V, Leguay T, et al: Pediatric-inspired intensified therapy of adult T-ALL reveals the favorable outcome of NOTCH1/ FBXW7 mutations, but not of low ERG/BAALC expression: A GRAALL study. Blood 118:5099- 5107, 2011
-
(2011)
Blood
, vol.118
, pp. 5099-5107
-
-
Ben Abdelali, R.1
Asnafi, V.2
Leguay, T.3
-
4
-
-
84873084751
-
Exome sequencing identifies mutation in CNOT3 and ribosomal genes RPL5 and RPL10 in T-cell acute lymphoblastic leukemia
-
De Keersmaecker K, Atak ZK, Li N, et al: Exome sequencing identifies mutation in CNOT3 and ribosomal genes RPL5 and RPL10 in T-cell acute lymphoblastic leukemia. Nat Genet 45:186-190, 2013
-
(2013)
Nat Genet
, vol.45
, pp. 186-190
-
-
De Keersmaecker, K.1
Atak, Z.K.2
Li, N.3
-
5
-
-
17144474314
-
Gene expression signatures define novel oncogenic pathways in T cell acute lymphoblastic leukemia
-
DOI 10.1016/S1535-6108(02)00018-1
-
Ferrando AA, Neuberg DS, Staunton J, et al: Gene expression signatures define novel oncogenic pathways in T cell acute lymphoblastic leukemia. Cancer Cell 1:75-87, 2002 (Pubitemid 41039178)
-
(2002)
Cancer Cell
, vol.1
, Issue.1
, pp. 75-87
-
-
Ferrando, A.A.1
Neuberg, D.S.2
Staunton, J.3
Loh, M.L.4
Huard, C.5
Raimondi, S.C.6
Behm, F.G.7
Pui, C.-H.8
Downing, J.R.9
Gilliland, D.G.10
Lander, E.S.11
Golub, T.R.12
Look, A.T.13
-
6
-
-
22044457152
-
HOXA genes are included in genetic and biologic networks defining human acute T-cell leukemia (T-ALL)
-
DOI 10.1182/blood-2004-10-3900
-
Soulier J, Clappier E, Cayuela JM, et al: HOXA genes are included in genetic and biologic networks defining human acute T-cell leukemia (T-ALL). Blood 106:274-286, 2005 (Pubitemid 40967203)
-
(2005)
Blood
, vol.106
, Issue.1
, pp. 274-286
-
-
Soulier, J.1
Clappier, E.2
Cayuela, J.-M.3
Regnault, A.4
Garcia-Peydro, M.5
Dombret, H.6
Baruchel, A.7
Toribio, M.-L.8
Sigaux, F.9
-
7
-
-
84867179824
-
The molecular basis of T cell acute lymphoblastic leukemia
-
Van Vlierberghe P, Ferrando A: The molecular basis of T cell acute lymphoblastic leukemia. J Clin Invest 122:3398-3406, 2012
-
(2012)
J Clin Invest
, vol.122
, pp. 3398-3406
-
-
Van Vlierberghe, P.1
Ferrando, A.2
-
8
-
-
84862907593
-
The genetic basis of early T-cell precursor acute lymphoblastic leukaemia
-
Zhang J, Ding L, Holmfeldt L, et al: The genetic basis of early T-cell precursor acute lymphoblastic leukaemia. Nature 481:157-163, 2012
-
(2012)
Nature
, vol.481
, pp. 157-163
-
-
Zhang, J.1
Ding, L.2
Holmfeldt, L.3
-
9
-
-
5044225888
-
Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia
-
DOI 10.1126/science.1102160
-
Weng AP, Ferrando AA, Lee W, et al: Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia. Science 306:269-271, 2004 (Pubitemid 39336870)
-
(2004)
Science
, vol.306
, Issue.5694
, pp. 269-271
-
-
Weng, A.P.1
Ferrando, A.A.2
Lee, W.3
Morris IV, J.P.4
Silverman, L.B.5
Sanchez-Irizarry, C.6
Blacklow, S.C.7
Look, A.T.8
Aster, J.C.9
-
10
-
-
34547780475
-
FBW7 mutations in leukemic cells mediate NOTCH pathway activation and resistance to γ-secretase inhibitors
-
DOI 10.1084/jem.20070876
-
O'Neil J, Grim J, Strack P, et al: FBW7 mutations in leukemic cells mediate NOTCH pathway activation and resistance to gamma-secretase inhibitors. J Exp Med 204:1813-1824, 2007 (Pubitemid 47236319)
-
(2007)
Journal of Experimental Medicine
, vol.204
, Issue.8
, pp. 1813-1824
-
-
O'Neil, J.1
Grim, J.2
Strack, P.3
Rao, S.4
Tibbitts, D.5
Winter, C.6
Hardwick, J.7
Welcker, M.8
Meijerink, J.P.9
Pieters, R.10
Draetta, G.11
Sears, R.12
Clurman, B.E.13
Look, A.T.14
-
11
-
-
28444490353
-
Induction therapy for adults with acute lymphoblastic leukemia: Results of more than 1500 patients from the international ALL trial: MRC UKALL XII/ECOG E2993
-
DOI 10.1182/blood-2005-04-1623
-
Rowe JM, Buck G, Burnett AK, et al: Induction therapy for adults with acute lymphoblastic leukemia: Results of more than 1500 patients from the international ALL trial: MRC UKALL XII/ECOG E2993. Blood 106:3760-3767, 2005 (Pubitemid 41739010)
-
(2005)
Blood
, vol.106
, Issue.12
, pp. 3760-3767
-
-
Rowe, J.M.1
Buck, G.2
Burnett, A.K.3
Chopra, R.4
Wiernik, P.H.5
Richards, S.M.6
Lazarus, H.M.7
Franklin, I.M.8
Litzow, M.R.9
Ciobanu, N.10
Prentice, H.G.11
Durrant, J.12
Tallman, M.S.13
Goldstone, A.H.14
-
12
-
-
79955005365
-
Minimal residual disease in acute lymphoblastic leukemia
-
Campana D: Minimal residual disease in acute lymphoblastic leukemia. Hematology Am Soc Hematol Educ Program 2010:7-12, 2010
-
(2010)
Hematology Am Soc Hematol Educ Program
, vol.2010
, pp. 7-12
-
-
Campana, D.1
-
13
-
-
60949101218
-
Pediatric-inspired therapy in adults with Philadelphia chromosome-negative acute lymphoblastic leukemia: The GRAALL-2003 study
-
Huguet F, Leguay T, Raffoux E, et al: Pediatric-inspired therapy in adults with Philadelphia chromosome-negative acute lymphoblastic leukemia: The GRAALL-2003 study. J Clin Oncol 27:911- 918, 2009
-
(2009)
J Clin Oncol
, vol.27
, pp. 911-918
-
-
Huguet, F.1
Leguay, T.2
Raffoux, E.3
-
14
-
-
79959248268
-
Posttranscriptional deregulation of MYC via PTEN constitutes a major alternative pathway of MYC activation in T-cell acute lymphoblastic leukemia
-
Bonnet M, Loosveld M, Montpellier B, et al: Posttranscriptional deregulation of MYC via PTEN constitutes a major alternative pathway of MYC activation in T-cell acute lymphoblastic leukemia. Blood 117:6650-6659, 2011
-
(2011)
Blood
, vol.117
, pp. 6650-6659
-
-
Bonnet, M.1
Loosveld, M.2
Montpellier, B.3
-
15
-
-
70149087158
-
High frequency of PTEN, PI3K, and AKT abnormalities in T-cell acute lymphoblastic leukemia
-
Gutierrez A, Sanda T, Grebliunaite R, et al: High frequency of PTEN, PI3K, and AKT abnormalities in T-cell acute lymphoblastic leukemia. Blood 114:647-650, 2009
-
(2009)
Blood
, vol.114
, pp. 647-650
-
-
Gutierrez, A.1
Sanda, T.2
Grebliunaite, R.3
-
16
-
-
33845382806
-
Nonparametric estimation from incomplete observations
-
Kaplan EL, Meier P: Nonparametric estimation from incomplete observations. J Am Stat Assoc 53:457-481, 1958
-
(1958)
J Am Stat Assoc
, vol.53
, pp. 457-481
-
-
Kaplan, E.L.1
Meier, P.2
-
17
-
-
0000336139
-
Regression models and life tables
-
Cox D: Regression models and life tables. J R Stat Soc B 34:187-220, 1972
-
(1972)
J R Stat Soc B
, vol.34
, pp. 187-220
-
-
Cox, D.1
-
18
-
-
27944450863
-
Concordance probability and discriminatory power in proportional hazards regression
-
DOI 10.1093/biomet/92.4.965
-
Gönen M, Heller G: Concordance probability and discriminative power of proportional hazards regression. Biometrika 92:965-970, 2005 (Pubitemid 41681247)
-
(2005)
Biometrika
, vol.92
, Issue.4
, pp. 965-970
-
-
Gonen, M.1
Heller, G.2
-
19
-
-
65449135968
-
NOTCH1/ FBXW7 mutation identifies a large subgroup with favorable outcome in adult T-cell acute lymphoblastic leukemia (T-ALL): A Group for Research on Adult Acute Lymphoblastic Leukemia (GRAALL) study
-
Asnafi V, Buzyn A, Le Noir S, et al: NOTCH1/ FBXW7 mutation identifies a large subgroup with favorable outcome in adult T-cell acute lymphoblastic leukemia (T-ALL): A Group for Research on Adult Acute Lymphoblastic Leukemia (GRAALL) study. Blood 113:3918-3924, 2009
-
(2009)
Blood
, vol.113
, pp. 3918-3924
-
-
Asnafi, V.1
Buzyn, A.2
Le Noir, S.3
-
20
-
-
52749085175
-
Molecular-genetic insights in paediatric T-cell acute lymphoblastic leukaemia
-
Van Vlierberghe P, Pieters R, Beverloo HB, et al: Molecular-genetic insights in paediatric T-cell acute lymphoblastic leukaemia. Br J Haematol 143: 153-168, 2008
-
(2008)
Br J Haematol
, vol.143
, pp. 153-168
-
-
Van Vlierberghe, P.1
Pieters, R.2
Beverloo, H.B.3
-
21
-
-
0032968708
-
The dynamics of T cell receptor signaling: Complex orchestration and the key roles of tempo and cooperation
-
DOI 10.1146/annurev.immunol.17.1.467
-
Germain RN, Stefanová I: The dynamics of T cell receptor signaling: Complex orchestration and the key roles of tempo and cooperation. Annu Rev Immunol 17:467-522, 1999 (Pubitemid 29241132)
-
(1999)
Annual Review of Immunology
, vol.17
, pp. 467-522
-
-
Germain, R.N.1
Stefanova, I.2
-
22
-
-
0036181869
-
PTEN: The down side of PI 3-kinase signalling
-
DOI 10.1016/S0898-6568(01)00234-0, PII S0898656801002340
-
Leslie NR, Downes CP: PTEN: The down side of PI 3-kinase signalling. Cell Signal 14:285-295, 2002 (Pubitemid 34164684)
-
(2002)
Cellular Signalling
, vol.14
, Issue.4
, pp. 285-295
-
-
Leslie, N.R.1
Downes C.Peter2
-
23
-
-
84860217431
-
The functions and regulation of the PTEN tumour suppressor
-
Song MS, Salmena L, Pandolfi PP: The functions and regulation of the PTEN tumour suppressor. Nat Rev Mol Cell Biol 13:283-296, 2012
-
(2012)
Nat Rev Mol Cell Biol
, vol.13
, pp. 283-296
-
-
Song, M.S.1
Salmena, L.2
Pandolfi, P.P.3
-
24
-
-
44349088690
-
Multi-genetic events collaboratively contribute to Pten-null leukaemia stem-cell formation
-
DOI 10.1038/nature06933, PII NATURE06933
-
Guo W, Lasky JL, Chang CJ, et al: Multigenetic events collaboratively contribute to Pten-null leukaemia stem-cell formation. Nature 453:529-533, 2008 (Pubitemid 351733319)
-
(2008)
Nature
, vol.453
, Issue.7194
, pp. 529-533
-
-
Guo, W.1
Lasky, J.L.2
Chang, C.-J.3
Mosessian, S.4
Lewis, X.5
Xiao, Y.6
Yeh, J.E.7
Chen, J.Y.8
Iruela-Arispe, M.L.9
Varella-Garcia, M.10
Wu, H.11
-
25
-
-
84878442961
-
NOTCH1 activation clinically antagonizes the unfavorable effect of PTEN inactivation in BFM-treated children with precursor T-cell acute lymphoblastic leukemia
-
Bandapalli OR, Zimmermann M, Kox C, et al: NOTCH1 activation clinically antagonizes the unfavorable effect of PTEN inactivation in BFM-treated children with precursor T-cell acute lymphoblastic leukemia. Haematologica 98:928-936, 2013
-
(2013)
Haematologica
, vol.98
, pp. 928-936
-
-
Bandapalli, O.R.1
Zimmermann, M.2
Kox, C.3
-
26
-
-
84865836687
-
The significance of PTEN and AKT aberrations in pediatric T-cell acute lymphoblastic leukemia
-
Zuurbier L, Petricoin EF 3rd, Vuerhard MJ, et al: The significance of PTEN and AKT aberrations in pediatric T-cell acute lymphoblastic leukemia. Haematologica 97:1405-1413, 2012
-
(2012)
Haematologica
, vol.97
, pp. 1405-1413
-
-
Zuurbier, L.1
Petricoin III, E.F.2
Vuerhard, M.J.3
-
27
-
-
33749320394
-
Oncogenic NRAS rapidly and efficiently induces CMML- And AML-like diseases in mice
-
DOI 10.1182/blood-2004-08-009498
-
Parikh C, Subrahmanyam R, Ren R: Oncogenic NRAS rapidly and efficiently induces CMML- and AML-like diseases in mice. Blood 108:2349-2357, 2006 (Pubitemid 44497519)
-
(2006)
Blood
, vol.108
, Issue.7
, pp. 2349-2357
-
-
Parikh, C.1
Subrahmanyam, R.2
Ren, R.3
-
28
-
-
60849083841
-
Oncogenic Kras-induced leukemogenesis: Hematopoietic stem cells as the initial target and lineage-specific progenitors as the potential targets for final leukemic transformation
-
Zhang J, Wang J, Liu Y, et al: Oncogenic Kras-induced leukemogenesis: Hematopoietic stem cells as the initial target and lineage-specific progenitors as the potential targets for final leukemic transformation. Blood 113:1304-1314, 2009
-
(2009)
Blood
, vol.113
, pp. 1304-1314
-
-
Zhang, J.1
Wang, J.2
Liu, Y.3
-
29
-
-
13544268759
-
RAS oncogene mutations and outcome of therapy for childhood acute lymphoblastic leukemia
-
DOI 10.1038/sj.leu.2403272
-
Perentesis JP, Bhatia S, Boyle E, et al: RAS oncogene mutations and outcome of therapy for childhood acute lymphoblastic leukemia. Leukemia 18:685-692, 2004 (Pubitemid 38500186)
-
(2004)
Leukemia
, vol.18
, Issue.4
, pp. 685-692
-
-
Perentesis, J.P.1
Bhatia, S.2
Boyle, E.3
Shao, Y.4
Shu, X.O.5
Steinbuch, M.6
Sather, H.N.7
Gaynon, P.8
Kiffmeyer, W.9
Envall-Fox, J.10
Robison, L.L.11
-
31
-
-
10244224017
-
Age-related phenotypic and oncogenic differences in T-cell acute lymphoblastic leukemias may reflect thymic atrophy
-
DOI 10.1182/blood-2003-11-3944
-
Asnafi V, Beldjord K, Libura M, et al: Agerelated phenotypic and oncogenic differences in T-cell acute lymphoblastic leukemias may reflect thymic atrophy. Blood 104:4173-4180, 2004 (Pubitemid 39620171)
-
(2004)
Blood
, vol.104
, Issue.13
, pp. 4173-4180
-
-
Asnafi, V.1
Beldjord, K.2
Libura, M.3
Villarese, P.4
Millien, C.5
Ballerini, P.6
Kuhlein, E.7
Lafage-Pochitaloff, M.8
Delabesse, E.9
Bernard, O.10
Macintyre, E.11
-
32
-
-
0027931276
-
Poor prognosis of prethymic phenotype acute lymphoblastic leukemia (pre-T-ALL)
-
Digel W, Schultze J, Kunzmann R, et al: Poor prognosis of prethymic phenotype acute lymphoblastic leukemia (pre-T-ALL). Leukemia 8:1406- 1408, 1994 (Pubitemid 24262501)
-
(1994)
Leukemia
, vol.8
, Issue.8
, pp. 1406-1408
-
-
Digel, W.1
Schultze, J.2
Kunzmann, R.3
Mertelsmann, R.4
Lindemann, A.5
-
33
-
-
0024539165
-
-)-cell leukemia and its clinical significance within adult acute lymphoblastic leukemia
-
Thiel E, Kranz BR, Raghavachar A, et al: Prethymic phenotype and genotype of pre-T (CD7-/ ER-)-cell leukemia and its clinical significance within adult acute lymphoblastic leukemia. Blood 73:1247- 1258, 1989 (Pubitemid 19107430)
-
(1989)
Blood
, vol.73
, Issue.5
, pp. 1247-1258
-
-
Thiel, E.1
Kranz, B.R.2
Raghavachar, A.3
Bartram, C.R.4
Loffler, H.5
Messerer, D.6
Ganser, A.7
Ludwig, W.-D.8
Buchner, T.9
Hoelzer, D.10
|