Aqueous nanomicellar formulation for topical delivery of biotinylated lipid prodrug of acyclovir: Formulation development and ocular biocompatibility

Journal of Ocular Pharmacology and Therapeutics

Volumn 30, Issue 1, 2014, Pages 49-58

  Vadlapudi, Aswani Dutt ^a   Cholkar, Kishore ^a   Vadlapatla, Ramya Krishna ^a   Mitra, Ashim K ^a  

^a UNIVERSITY OF MISSOURI KANSAS CITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACICLOVIR; BIOTIN 12HYDROXYSTEARIC ACID ACYCLOVIR; BIOTIN DERIVATIVE; GAMMA INTERFERON; INTERLEUKIN 17; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; MESSENGER RNA; NANOCARRIER; NONIONIC SURFACTANT; OCTOXINOL; PRODRUG; TOCOFERSOLAN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ARTICLE; BIOCOMPATIBILITY; BIOTINYLATION; CELL PROLIFERATION ASSAY; CELL VIABILITY; CONTROLLED STUDY; CORNEA CELL; CORNEA EPITHELIUM; CRITICAL MICELLE CONCENTRATION; CYTOTOXICITY; CYTOTOXICITY ASSAY; DRUG DELIVERY SYSTEM; DRUG FORMULATION; EVAPORATION; HERPES SIMPLEX KERATITIS; HUMAN; HUMAN CELL; IN VITRO STUDY; MICELLE; MICELLIZATION; NANOENCAPSULATION; PARTICLE SIZE; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; SUSTAINED DRUG RELEASE; TOPICAL TREATMENT; TRANSMISSION ELECTRON MICROSCOPY; ZETA POTENTIAL;

ACYCLOVIR; ADMINISTRATION, OPHTHALMIC; ANTIVIRAL AGENTS; BIOTINYLATION; CYTOKINES; DRUG DELIVERY SYSTEMS; EPITHELIUM, CORNEAL; GENE EXPRESSION REGULATION; HUMANS; KERATITIS, HERPETIC; LIPIDS; MICELLES; NANOPARTICLES; OCTOXYNOL; PARTICLE SIZE; POLYETHYLENE GLYCOLS; PRODRUGS; REAL-TIME POLYMERASE CHAIN REACTION; SURFACE-ACTIVE AGENTS; VITAMIN E;

EID: 84892922207     PISSN: 10807683     EISSN: 15577732     Source Type: Journal    
DOI: 10.1089/jop.2013.0157     Document Type: Article

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