A critical review of anaesthetised animal models and alternatives for military research, testing and training, with a focus on blast damage, haemorrhage and resuscitation

ATLA Alternatives to Laboratory Animals

Volumn 41, Issue 5, 2013, Pages 385-415

  Combes, Robert D ^a  

^a RUSSELL AND BURCH HOUSE   (United Kingdom)

Author keywords

Aerosolised biological weapons; Anaesthetised animal models; Animal welfare; Chemical weapons; Computer modelling; Coordination; Haemorrhage; Harmonisation; Increased transparency; Mathematical modelling; Military research; Organotypic cultures; Resuscitation training; Surgical training; Traumatic brain injury; Validation

Indexed keywords

ANESTHETIC AGENT; N METHYL DEXTRO ASPARTIC ACID RECEPTOR;

ACCELERATION; ANESTHESIA; ANIMAL; ANIMAL BEHAVIOR; ANIMAL TESTING ALTERNATIVE; ANIMAL TESTING REPLACEMENT; ANIMAL USE; BLAST INJURY; BLEEDING; BLOOD BRAIN BARRIER; BREATHING; CADAVER; CARDIOVASCULAR EFFECT; CARDIOVASCULAR SYSTEM; CELL FUNCTION; COMPRESSION; COMPUTER; COMPUTER MODEL; ELECTROENCEPHALOGRAM; EXPERIMENTAL ANIMAL WELFARE; EXPERIMENTAL MODEL; FIELD EXPERIMENT; GENERAL ANESTHESIA; HEMODYNAMICS; HOLISTIC CARE; HUMAN; IN VITRO STUDY; INVASIVE PROCEDURE; MATHEMATICAL MODEL; MILITARY RESEARCH; NERVE CELL; NEUROPROTECTION; NONHUMAN; PAIN; PRIORITY JOURNAL; RECEPTOR BINDING; RESUSCITATION; REVIEW; SHOCK; SIMULATOR; TARGET ORGAN; TISSUE CULTURE; TRAINING; TRAUMATIC BRAIN INJURY;

ANESTHESIA; ANIMAL WELFARE; ANIMALS; BLAST INJURIES; BRAIN INJURIES; FEMALE; HEMORRHAGE; HUMANS; MALE; MILITARY SCIENCE; MODELS, ANIMAL; RESUSCITATION;

EID: 84892899669     PISSN: 02611929     EISSN: None     Source Type: Journal    
DOI: 10.1177/026119291304100508     Document Type: Review

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