The injured lung: Clinical issues and experimental models

Philosophical Transactions of the Royal Society B: Biological Sciences

Volumn 366, Issue 1562, 2011, Pages 306-309

  Jugg, B J A ^a   Smith, A J ^a   Rudall, S J ^a   Rice, P ^a  

^a Biomedical Sciences Department   (United Kingdom)

Author keywords

Acute lung injury; Acute respiratory distress syndrome; Porcine; Toxic chemicals; Treatment strategies

Indexed keywords

CIVIL SOCIETY; POLLUTION EXPOSURE; RESPIRATORY DISEASE; TOXIC SUBSTANCE;

SUS;

EID: 79251489128     PISSN: 09628436     EISSN: 14712970     Source Type: Journal    
DOI: 10.1098/rstb.2010.0235     Document Type: Conference Paper

References (27)

1. Marrs, T. C., Maynard, R. L. & Sidell, F. R. 1996 Mustard gas. In Chemical warfare agents: Toxicology and treatments, pp. 139-173. Chichester, UK: John Wiley and Sons Ltd.
2. Evison,D., Hinsley, D. & Rice,P. 2002 Chemical Weapons. Br. Med. J. 324, 332-335. (doi:10.1136/bmj.324.7333. 332)
3. Bell, D. G. 2007 Severe lung injury following exposure to chlorine gas: A case series (abstract). Chest 132, 566.
4. Borak, J. & Diller, W. F. 2001 Phosgene exposure: Mechanisms of injury and treatment strategies. J. Occup. Environ. Med. 43, 110-119. (10.1097/00043764-20010 2000-00008)
5. Grainge, C. & Rice, P. 2010 Management of phosgene induced acute lung injury. Clin. Toxicol. 48, 497-508. (doi:10.3109/15563650.2010.506877)
6. Ware, L. B. & Matthay, M. A. 2000 The acute respiratory distress syndrome. N. Engl. J. Med. 342, 1334-1349. (doi:10.1056/NEJM200005043421806)
7. Parkhouse, D. A., Brown, R. F. R., Jugg, B. J. A., Harban, F. M., Platt, J., Kenward, C. E., Jenner, J., Rice, P. & Smith, A. J. 2007 Protective ventilation strategies in the management of phosgene-induced acute lung injury. Mil. Med. 172, 295-300.
8. Prentiss, A. M. 1937 Vesicant agents. In Chemicals in war: A treatise on chemical warfare, pp. 177-200, 1st edn. London, UK: Maple Press Co.
9. Hefazi, M., Attaran,D.,Mahmoudi,M. & Balali-Mood,M. 2005 Late respiratory complications of mustard gas poisoning in Iranian veterans. Inhal. Toxicol. 17, 587-592. (doi:10. 1080/08958370591000591)
10. Pechura, C. M. & Rall, D. P. 1993 History and analysis of mustard agent and lewisite research programs in the United States. In Veterans at risk: The health effects of mustard gas and lewisite, pp. 21-60. Washington, DC: Institute of Medicine, National Academic Press.
11. Okumura, T. et al. 2005 The Tokyo subway sarin attack-lessons learned. Toxicol. Appl. Pharmacol. 207, S471-S476. (10.1016/j.taap.2005.02.032)
12. Wang, J., Winskog, C., Edston, E. & Walther, S. M. 2005 Inhaled and intravenous corticosteroids both attenuate chlorine gas-induced lung injury in pigs. Acta Anaesthesiol. Scand. 49, 183-190. (doi:10.1111/j.1399-6576. 2004.00563.x)
13. Evans, R. B. 2005 Chlorine: State of the art. Lung 183, 151-167. (doi:10.1007/s00408-004-2530-3)
14. Van Sickle, D. et al. 2009 Acute health effects after exposure to chlorine gas released after a train derailment. Am. J. Emerg. Med. 2, 1-7. (doi:10.1016/j.ajem.2007. 12.006)
15. Grainge, C., Brown, R. F. R., Jugg, B. J. A., Smith, A. J., Mann, T. M., Jenner, J., Rice, P. & Parkhouse, D. A. 2009 Early treatment with nebulised salbutamol worsens physiological measures and does not improve survival following phosgene induced acute lung injury. J. R. Army Med. Corps 155, 105-109.
16. Hodgetts, T. 2009 Emergency care on the battlefield. See http://www.nhs.uk/Livewell/Militarymedicine/Pages/ Survivingbattlefield.aspx (accessed 25/01/2010).
17. Anderson, D. R., Taylor, S. L., Fetterer, D. P. & Holmes, W.W. 2009 Evaluation of protease inhibitors and an antioxidant for treatments of sulphur mustard-induced toxic lung injury. Toxicology 263, 41-46. (doi:10.1016/j.tox. 2008.08.025)
18. Hossein, B. M., Nasim, V. & Sediqa, A. 2008 The protective effect of Nigella sativa on lung injury of sulphur mustard-exposed Guinea pigs. Exp. Lung Res. 34, 183-194. (doi:10.1080/01902140801935082)
19. Getty, R. 1975 Sisson and Grossman's The anatomy of domestic animals-Porcine, vol. 2 (eds S. Sisson, J. D. Grossman & R. Getty), pp. 1215-1422. Philadelphia, PA: WB Saunders.
20. Cramer, D. V. & Makowka, L. 1994 Handbook of animal models in transplantation research (eds D. V. Cramer, L. G. Posesta & L. Makowka), Boca Raton, FL: CRC Press.
21. Brown, R. F. R., Jugg, B. J. A., Harban, F. M. J., Ashley, Z., Kenward, C. E., Platt, J., Hill, A., Rice, P. & Watkins, P. E. 2002 Pathophysiological responses following phosgene exposure in the anaesthetized pig. J. Appl. Toxicol. 22, 263-269. (doi:10.1002/jat.857)
22. Smith, A. J., Parkhouse, D. A., Brown, R. F. R., Jugg, B. J. A., Platt, J., Mann, T., Masey, C., Jenner, J. & Rice, P. 2009 The effect of steroid treatment with inhaled budesonide or intravenous methylprednisolone on phosgene- induced acute lung injury in a porcine model. Mil. Med. 174, 1-8.
23. The Acute Respiratory Distress Syndrome Network. 2000 Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and acute respiratory distress syndrome. N. Engl. J. Med. 342, 1301-1308. (doi:10.1056/NEJM200005043421801)
24. Grainge, C., Jugg, B. J. A., Smith, A. J., Brown, R. F. R., Jenner, J., Parkhouse, D. A., Martin, N. & Rice, P. 2010 Delayed low dose supplemental oxygen improves survival following phosgene induced acute lung injury. Inhal. Toxicol. 22, 552-560. (doi:10.3109/0895837090 3571831)
25. Fairhall, S. J., Brown, R. F. R., Jugg, B. J. A., Smith, A. J., Mann, T.M., Jenner, J. & Sciuto, A. M. 2008 Preliminary studies of sulphur mustard induced lung injury in the terminally anaesthetised pig: Exposure system and methodology. Toxicol. Mech. Methods 18, 355-362. (doi:10. 1080/ 15376510701623383)
26. Willems, J. L. 1989 Clinical management of mustard gas casualties. Ann. Med. Mil. (Belgicae) 3, 1-61.
27. Newman-Taylor, A. J. & Morris, A. J. R. 1991 Experience with mustard gas casualties. Lancet 337, 242. (doi:10.1016/0140-6736(91)92210-S)