Exploring the effects of tert-butylhydroperoxide induced liver injury using proteomic approach

Toxicology

Volumn 316, Issue 1, 2014, Pages 61-70

  Shen, Chien Heng ^a,b   Tung, Shui Yi ^a,b   Huang, Wen Shih ^a,b   Lu, Chien Chang ^b   Lee, Ko Chao ^b   Hsieh, Yung Yu ^a   Chang, Pey Jium ^b   Liang, Hwey Fang ^c,d   Chen, Jiann Hwa ^e,f,g   Lin, Tseng Hsi ^h,i   Hsieh, Meng Chiao ^a,b   Kuo, Hsing Chun ^c,d  

^a CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

^b CHANG GUNG UNIVERSITY COLLEGE OF MEDICINE   (Taiwan)

^c CHANG GUNG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Taiwan)

^d CGUST   (Taiwan)

^e FU JEN CATHOLIC UNIVERSITY   (Taiwan)

^f NATIONAL YANG MING UNIVERSITY   (Taiwan)

^g CATHAY GENERAL HOSPITAL   (Taiwan)

^h TAICHUNG VETERANS GENERAL HOSPITAL   (Taiwan)

ⁱ CHUNG SHAN MEDICAL UNIVERSITY   (Taiwan)

Author keywords

ETFA; IRE1 alpha TRAF2; JNK1 2; NF B; ROS; T BHP

Indexed keywords

ELECTRON TRANSFERRING FLAVOPROTEIN; ELECTRON TRANSFERRING FLAVOPROTEIN SUBUNIT ALPHA; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN IRE1; PROTEIN IRE1 ALPHA; PROTEIN P50; SHORT HAIRPIN RNA; STRESS ACTIVATED PROTEIN KINASE 1; SYNAPTOTAGMIN I; TERT BUTYL HYDROPEROXIDE; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 2; UNCLASSIFIED DRUG;

ADULT; ANIMAL CELL; APOPTOSIS; ARTICLE; CELL LEVEL; CELL VIABILITY; COMPLEX FORMATION; CONTROLLED STUDY; CYTOTOXICITY; DIFFERENTIAL DISPLAY; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; IN VIVO STUDY; LIVER CELL; LIVER CELL DAMAGE; LIVER TOXICITY; MALE; NONHUMAN; OXIDATIVE STRESS; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN CONTENT; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEOMICS; SIGNAL TRANSDUCTION; TWO DIMENSIONAL ELECTROPHORESIS; UPREGULATION;

ETFA; IRE1-ALPHA/TRAF2; JNK1/2; NFΚB; ROS; T-BHP;

ANIMALS; APOPTOSIS; CELL SURVIVAL; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG-INDUCED LIVER INJURY; ELECTRON-TRANSFERRING FLAVOPROTEINS; ENDOPLASMIC RETICULUM STRESS; HEPATOCYTES; HUMANS; LIVER; MALE; PROTEOMICS; RATS; RATS, SPRAGUE-DAWLEY; RATS, WISTAR; TERT-BUTYLHYDROPEROXIDE; UP-REGULATION;

EID: 84892854049     PISSN: 0300483X     EISSN: 18793185     Source Type: Journal    
DOI: 10.1016/j.tox.2013.12.007     Document Type: Article

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