Mechanism of tert-butylhydroperoxide induced cytotoxicity in U-937 macrophages by alteration of mitochondrial function and generation of ROS

Toxicology in Vitro

Volumn 21, Issue 5, 2007, Pages 846-854

  Kanupriya, ^a   Prasad, D ^a   Sai Ram, M ^a   Sawhney, R C ^a   Ilavazhagan, G ^a   Banerjee, P K ^a  

^a DEFENCE INSTITUTE OF PHYSIOLOGY AND ALLIED SCIENCES   (India)

Author keywords

Apoptosis; Caspase 3; Cytochrome c; DNA fragmentation; Oxidative stress; tert Butylhydroperoxide

Indexed keywords

CALCIUM ION; CASPASE 3; CASPASE 3 INHIBITOR; CYTOCHROME C; LIPOCORTIN 5; PROTEIN BAX; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE; TERT BUTYL HYDROPEROXIDE;

APOPTOSIS; ARTICLE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CELL CULTURE; CELL LINE; CONCENTRATION (PARAMETERS); CYTOTOXICITY; ENZYME ACTIVATION; HUMAN; HUMAN CELL; MACROPHAGE FUNCTION; MITOCHONDRIAL MEMBRANE; MITOCHONDRION; PROTEIN EXPRESSION; TIME;

ANNEXIN A5; APOPTOSIS; BENZIMIDAZOLES; BLOTTING, WESTERN; CALCIUM; CASPASE 3; CELL LINE; CELL SURVIVAL; COLORING AGENTS; DNA FRAGMENTATION; FLUORESCENT DYES; GLUTATHIONE; HUMANS; L-LACTATE DEHYDROGENASE; MACROPHAGES; MEMBRANE POTENTIALS; MITOCHONDRIA; PROPIDIUM; REACTIVE OXYGEN SPECIES; TERT-BUTYLHYDROPEROXIDE;

EID: 34247165198     PISSN: 08872333     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tiv.2007.02.007     Document Type: Article

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