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Volumn 155, Issue 2, 2014, Pages 403-412

Etifoxine analgesia in experimental monoarthritis: A combined action that protects spinal inhibition and limits central inflammatory processes

Author keywords

BDNF; Central inflammation; COX2; GABA; Glycine; Microglia; Nonbenzodiazepine anxiolytic; PGE2; Spinal pain processing

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; ANXIOLYTIC AGENT; CYCLOOXYGENASE 2; ETIFOXINE; INTERLEUKIN 1BETA; INTERLEUKIN 6; OX 42 PROTEIN; PROSTAGLANDIN E RECEPTOR 2; PROSTAGLANDIN E RECEPTOR 3; PROSTAGLANDIN E RECEPTOR 4; PROSTAGLANDIN E2; PROTEIN; STRESAM; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

EID: 84892809509     PISSN: 03043959     EISSN: 18726623     Source Type: Journal    
DOI: 10.1016/j.pain.2013.11.003     Document Type: Article
Times cited : (18)

References (51)
  • 1
    • 0036139423 scopus 로고    scopus 로고
    • PGE(2) selectively blocks inhibitory glycinergic neurotransmission onto rat superficial dorsal horn neurons
    • S. Ahmadi, S. Lippross, W.L. Neuhuber, and H.U. Zeilhofer PGE(2) selectively blocks inhibitory glycinergic neurotransmission onto rat superficial dorsal horn neurons Nat Neurosci 5 2002 34 40
    • (2002) Nat Neurosci , vol.5 , pp. 34-40
    • Ahmadi, S.1    Lippross, S.2    Neuhuber, W.L.3    Zeilhofer, H.U.4
  • 2
    • 70449672361 scopus 로고    scopus 로고
    • Reduction and prevention of vincristine-induced neuropathic pain symptoms by the non-benzodiazepine anxiolytic etifoxine are mediated by 3alpha-reduced neurosteroids
    • M. Aouad, A. Charlet, J.L. Rodeau, and P. Poisbeau Reduction and prevention of vincristine-induced neuropathic pain symptoms by the non-benzodiazepine anxiolytic etifoxine are mediated by 3alpha-reduced neurosteroids PAIN® 147 2009 54 59
    • (2009) PAIN® , vol.147 , pp. 54-59
    • Aouad, M.1    Charlet, A.2    Rodeau, J.L.3    Poisbeau, P.4
  • 3
    • 84896693507 scopus 로고    scopus 로고
    • Etifoxine stimulates allopregnanolone synthesis in the spinal cord to produce analgesia in experimental mononeuropathy
    • 10.1002/j.1532-2149.2013.00367.x [Epub ahead of print]
    • M. Aouad, N. Petit-Demouliere, Y. Goumon, and P. Poisbeau Etifoxine stimulates allopregnanolone synthesis in the spinal cord to produce analgesia in experimental mononeuropathy Eur J Pain 2013 10.1002/j.1532-2149.2013.00367.x [Epub ahead of print]
    • (2013) Eur J Pain
    • Aouad, M.1    Petit-Demouliere, N.2    Goumon, Y.3    Poisbeau, P.4
  • 4
    • 49449108807 scopus 로고    scopus 로고
    • Antinociceptive effects of tumor necrosis factor alpha neutralization in a rat model of antigen-induced arthritis: Evidence of a neuronal target
    • M.K. Boettger, S. Hensellek, F. Richter, M. Gajda, R. Stockigt, G.S. von Banchet, R. Brauer, and H.G. Schaible Antinociceptive effects of tumor necrosis factor alpha neutralization in a rat model of antigen-induced arthritis: evidence of a neuronal target Arthritis Rheum 58 2008 2368 2378
    • (2008) Arthritis Rheum , vol.58 , pp. 2368-2378
    • Boettger, M.K.1    Hensellek, S.2    Richter, F.3    Gajda, M.4    Stockigt, R.5    Von Banchet, G.S.6    Brauer, R.7    Schaible, H.G.8
  • 5
    • 77951719845 scopus 로고    scopus 로고
    • Spinal tumor necrosis factor alpha neutralization reduces peripheral inflammation and hyperalgesia and suppresses autonomic responses in experimental arthritis: A role for spinal tumor necrosis factor alpha during induction and maintenance of peripheral inflammation
    • M.K. Boettger, K. Weber, D. Grossmann, M. Gajda, R. Bauer, K.J. Bar, S. Schulz, A. Voss, C. Geis, R. Brauer, and H.G. Schaible Spinal tumor necrosis factor alpha neutralization reduces peripheral inflammation and hyperalgesia and suppresses autonomic responses in experimental arthritis: a role for spinal tumor necrosis factor alpha during induction and maintenance of peripheral inflammation Arthritis Rheum 62 2010 1308 1318
    • (2010) Arthritis Rheum , vol.62 , pp. 1308-1318
    • Boettger, M.K.1    Weber, K.2    Grossmann, D.3    Gajda, M.4    Bauer, R.5    Bar, K.J.6    Schulz, S.7    Voss, A.8    Geis, C.9    Brauer, R.10    Schaible, H.G.11
  • 6
    • 33645231857 scopus 로고    scopus 로고
    • Survey of chronic pain in Europe: Prevalence, impact on daily life, and treatment
    • H. Breivik, B. Collett, V. Ventafridda, R. Cohen, and D. Gallacher Survey of chronic pain in Europe: prevalence, impact on daily life, and treatment Eur J Pain 10 2006 287 333
    • (2006) Eur J Pain , vol.10 , pp. 287-333
    • Breivik, H.1    Collett, B.2    Ventafridda, V.3    Cohen, R.4    Gallacher, D.5
  • 7
    • 33846218186 scopus 로고    scopus 로고
    • Sensitization of unmyelinated sensory fibers of the joint nerve to mechanical stimuli by interleukin-6 in the rat: An inflammatory mechanism of joint pain
    • D. Brenn, F. Richter, and H.G. Schaible Sensitization of unmyelinated sensory fibers of the joint nerve to mechanical stimuli by interleukin-6 in the rat: an inflammatory mechanism of joint pain Arthritis Rheum 56 2007 351 359
    • (2007) Arthritis Rheum , vol.56 , pp. 351-359
    • Brenn, D.1    Richter, F.2    Schaible, H.G.3
  • 8
    • 0026503721 scopus 로고
    • A limited arthritic model for chronic pain studies in the rat
    • S.H. Butler, F. Godefroy, J.M. Besson, and J. Weil-Fugazza A limited arthritic model for chronic pain studies in the rat PAIN® 48 1992 73 81
    • (1992) PAIN® , vol.48 , pp. 73-81
    • Butler, S.H.1    Godefroy, F.2    Besson, J.M.3    Weil-Fugazza, J.4
  • 9
    • 53349127737 scopus 로고    scopus 로고
    • Fast non-genomic effects of progesterone-derived neurosteroids on nociceptive thresholds and pain symptoms
    • A. Charlet, F. Lasbennes, P. Darbon, and P. Poisbeau Fast non-genomic effects of progesterone-derived neurosteroids on nociceptive thresholds and pain symptoms PAIN® 139 2008 603 609
    • (2008) PAIN® , vol.139 , pp. 603-609
    • Charlet, A.1    Lasbennes, F.2    Darbon, P.3    Poisbeau, P.4
  • 10
    • 43049148389 scopus 로고    scopus 로고
    • Effects of progesterone on intestinal inflammatory response, mucosa structure alterations, and apoptosis following traumatic brain injury in male rats
    • G. Chen, J.X. Shi, M. Qi, H.X. Wang, and C.H. Hang Effects of progesterone on intestinal inflammatory response, mucosa structure alterations, and apoptosis following traumatic brain injury in male rats J Surg Res 147 2008 92 98
    • (2008) J Surg Res , vol.147 , pp. 92-98
    • Chen, G.1    Shi, J.X.2    Qi, M.3    Wang, H.X.4    Hang, C.H.5
  • 11
    • 0028928838 scopus 로고
    • Role of peri-axonal inflammation in the development of thermal hyperalgesia and guarding behavior in a rat model of neuropathic pain
    • A.L. Clatworthy, P.A. Illich, G.A. Castro, and E.T. Walters Role of peri-axonal inflammation in the development of thermal hyperalgesia and guarding behavior in a rat model of neuropathic pain Neurosci Lett 184 1995 5 8
    • (1995) Neurosci Lett , vol.184 , pp. 5-8
    • Clatworthy, A.L.1    Illich, P.A.2    Castro, G.A.3    Walters, E.T.4
  • 14
    • 0034463226 scopus 로고    scopus 로고
    • Spinal synthesis and release of prostanoids after peripheral injury and inflammation
    • D.M. Dirig, and T.L. Yaksh Spinal synthesis and release of prostanoids after peripheral injury and inflammation Adv Exp Med Biol 469 1999 401 408
    • (1999) Adv Exp Med Biol , vol.469 , pp. 401-408
    • Dirig, D.M.1    Yaksh, T.L.2
  • 15
    • 38049183151 scopus 로고    scopus 로고
    • Neurokinin-1 (NK-1) receptor and brain-derived neurotrophic factor (BDNF) gene expression is differentially modulated in the rat spinal dorsal horn and hippocampus during inflammatory pain
    • V. Duric, and K.E. McCarson Neurokinin-1 (NK-1) receptor and brain-derived neurotrophic factor (BDNF) gene expression is differentially modulated in the rat spinal dorsal horn and hippocampus during inflammatory pain Mol Pain 3 2007 32
    • (2007) Mol Pain , vol.3 , pp. 32
    • Duric, V.1    McCarson, K.E.2
  • 16
    • 0032777775 scopus 로고    scopus 로고
    • The intraspinal release of prostaglandin E2 in a model of acute arthritis is accompanied by an up-regulation of cyclooxygenase-2 in the spinal cord
    • A. Ebersberger, B.D. Grubb, H.L. Willingale, N.J. Gardiner, J. Nebe, and H.G. Schaible The intraspinal release of prostaglandin E2 in a model of acute arthritis is accompanied by an up-regulation of cyclooxygenase-2 in the spinal cord Neuroscience 93 1999 775 781
    • (1999) Neuroscience , vol.93 , pp. 775-781
    • Ebersberger, A.1    Grubb, B.D.2    Willingale, H.L.3    Gardiner, N.J.4    Nebe, J.5    Schaible, H.G.6
  • 18
    • 0021943708 scopus 로고
    • Sensory receptors in ankle joint capsules of normal and arthritic rats
    • G. Guilbaud, A. Iggo, and R. Tegner Sensory receptors in ankle joint capsules of normal and arthritic rats Exp Brain Res 58 1985 29 40
    • (1985) Exp Brain Res , vol.58 , pp. 29-40
    • Guilbaud, G.1    Iggo, A.2    Tegner, R.3
  • 19
    • 0037628261 scopus 로고    scopus 로고
    • The modulatory effects of the anxiolytic etifoxine on GABA(A) receptors are mediated by the beta subunit
    • A. Hamon, A. Morel, B. Hue, M. Verleye, and J.M. Gillardin The modulatory effects of the anxiolytic etifoxine on GABA(A) receptors are mediated by the beta subunit Neuropharmacology 45 2003 293 303
    • (2003) Neuropharmacology , vol.45 , pp. 293-303
    • Hamon, A.1    Morel, A.2    Hue, B.3    Verleye, M.4    Gillardin, J.M.5
  • 20
    • 33751531210 scopus 로고    scopus 로고
    • Progesterone receptor plays a major antiinflammatory role in human myometrial cells by antagonism of nuclear factor-kappaB activation of cyclooxygenase 2 expression
    • D.B. Hardy, B.A. Janowski, D.R. Corey, and C.R. Mendelson Progesterone receptor plays a major antiinflammatory role in human myometrial cells by antagonism of nuclear factor-kappaB activation of cyclooxygenase 2 expression Mol Endocrinol 20 2006 2724 2733
    • (2006) Mol Endocrinol , vol.20 , pp. 2724-2733
    • Hardy, D.B.1    Janowski, B.A.2    Corey, D.R.3    Mendelson, C.R.4
  • 22
    • 84879783346 scopus 로고    scopus 로고
    • Neurohormonal effects of oxytocin and vasopressin receptor agonists on spinal pain processing in male rats
    • P.E. Juif, and P. Poisbeau Neurohormonal effects of oxytocin and vasopressin receptor agonists on spinal pain processing in male rats PAIN® 154 2013 1449 1456
    • (2013) PAIN® , vol.154 , pp. 1449-1456
    • Juif, P.E.1    Poisbeau, P.2
  • 23
    • 0035887592 scopus 로고    scopus 로고
    • Region-specific developmental specialization of GABA-glycine cosynapses in laminas I-II of the rat spinal dorsal horn
    • A.F. Keller, J.A. Coull, N. Chery, P. Poisbeau, and Y. De Koninck Region-specific developmental specialization of GABA-glycine cosynapses in laminas I-II of the rat spinal dorsal horn J Neurosci 21 2001 7871 7880
    • (2001) J Neurosci , vol.21 , pp. 7871-7880
    • Keller, A.F.1    Coull, J.A.2    Chery, N.3    Poisbeau, P.4    De Koninck, Y.5
  • 24
    • 0036500990 scopus 로고    scopus 로고
    • Fibroblast growth factor-2 converts PACAP growth action on embryonic hindbrain precursors from stimulation to inhibition
    • V. Lelievre, Z. Hu, J.Y. Byun, Y. Ioffe, and J.A. Waschek Fibroblast growth factor-2 converts PACAP growth action on embryonic hindbrain precursors from stimulation to inhibition J Neurosci Res 67 2002 566 573
    • (2002) J Neurosci Res , vol.67 , pp. 566-573
    • Lelievre, V.1    Hu, Z.2    Byun, J.Y.3    Ioffe, Y.4    Waschek, J.A.5
  • 25
    • 34548256858 scopus 로고    scopus 로고
    • Systemic antiinflammatory corticosteroid reduces mechanical pain behavior, sympathetic sprouting, and elevation of proinflammatory cytokines in a rat model of neuropathic pain
    • H. Li, W. Xie, J.A. Strong, and J.M. Zhang Systemic antiinflammatory corticosteroid reduces mechanical pain behavior, sympathetic sprouting, and elevation of proinflammatory cytokines in a rat model of neuropathic pain Anesthesiology 107 2007 469 477
    • (2007) Anesthesiology , vol.107 , pp. 469-477
    • Li, H.1    Xie, W.2    Strong, J.A.3    Zhang, J.M.4
  • 27
    • 40149098353 scopus 로고    scopus 로고
    • Presynaptic functional trkB receptors mediate the release of excitatory neurotransmitters from primary afferent terminals in lamina II (substantia gelatinosa) of postnatal rat spinal cord
    • A. Merighi, R. Bardoni, C. Salio, L. Lossi, F. Ferrini, M. Prandini, M. Zonta, S. Gustincich, and G. Carmignoto Presynaptic functional trkB receptors mediate the release of excitatory neurotransmitters from primary afferent terminals in lamina II (substantia gelatinosa) of postnatal rat spinal cord Dev Neurobiol 68 2008 457 475
    • (2008) Dev Neurobiol , vol.68 , pp. 457-475
    • Merighi, A.1    Bardoni, R.2    Salio, C.3    Lossi, L.4    Ferrini, F.5    Prandini, M.6    Zonta, M.7    Gustincich, S.8    Carmignoto, G.9
  • 28
    • 0034831641 scopus 로고    scopus 로고
    • A double blind parallel group placebo controlled comparison of sedative and mnesic effects of etifoxine and lorazepam in healthy subjects
    • J. Micallef, C. Soubrouillard, F. Guet, M.E. Le Guern, C. Alquier, B. Bruguerolle, and O. Blin A double blind parallel group placebo controlled comparison of sedative and mnesic effects of etifoxine and lorazepam in healthy subjects Fundam Clin Pharmacol 15 2001 209 216
    • (2001) Fundam Clin Pharmacol , vol.15 , pp. 209-216
    • Micallef, J.1    Soubrouillard, C.2    Guet, F.3    Le Guern, M.E.4    Alquier, C.5    Bruguerolle, B.6    Blin, O.7
  • 29
    • 0028206220 scopus 로고
    • Characterization of EP-receptor subtypes involved in allodynia and hyperalgesia induced by intrathecal administration of prostaglandin E2 to mice
    • T. Minami, I. Nishihara, R. Uda, S. Ito, M. Hyodo, and O. Hayaishi Characterization of EP-receptor subtypes involved in allodynia and hyperalgesia induced by intrathecal administration of prostaglandin E2 to mice Br J Pharmacol 112 1994 735 740
    • (1994) Br J Pharmacol , vol.112 , pp. 735-740
    • Minami, T.1    Nishihara, I.2    Uda, R.3    Ito, S.4    Hyodo, M.5    Hayaishi, O.6
  • 30
    • 0028363557 scopus 로고
    • Allodynia evoked by intrathecal administration of prostaglandin E2 to conscious mice
    • T. Minami, R. Uda, S. Horiguchi, S. Ito, M. Hyodo, and O. Hayaishi Allodynia evoked by intrathecal administration of prostaglandin E2 to conscious mice PAIN® 57 1994 217 223
    • (1994) PAIN® , vol.57 , pp. 217-223
    • Minami, T.1    Uda, R.2    Horiguchi, S.3    Ito, S.4    Hyodo, M.5    Hayaishi, O.6
  • 31
    • 0027372795 scopus 로고
    • N-methyl-d-aspartate (NMDA) and non-NMDA receptor antagonists block the hyperexcitability of dorsal horn neurons during development of acute arthritis in rat's knee joint
    • V. Neugebauer, T. Lucke, and H.G. Schaible N-methyl-d-aspartate (NMDA) and non-NMDA receptor antagonists block the hyperexcitability of dorsal horn neurons during development of acute arthritis in rat's knee joint J Neurophysiol 70 1993 1365 1377
    • (1993) J Neurophysiol , vol.70 , pp. 1365-1377
    • Neugebauer, V.1    Lucke, T.2    Schaible, H.G.3
  • 32
    • 33646377162 scopus 로고    scopus 로고
    • Efficacy of etifoxine compared to lorazepam monotherapy in the treatment of patients with adjustment disorders with anxiety: A double-blind controlled study in general practice
    • N. Nguyen, E. Fakra, V. Pradel, E. Jouve, C. Alquier, M.E. Le Guern, J. Micallef, and O. Blin Efficacy of etifoxine compared to lorazepam monotherapy in the treatment of patients with adjustment disorders with anxiety: a double-blind controlled study in general practice Hum Psychopharmacol 21 2006 139 149
    • (2006) Hum Psychopharmacol , vol.21 , pp. 139-149
    • Nguyen, N.1    Fakra, E.2    Pradel, V.3    Jouve, E.4    Alquier, C.5    Le Guern, M.E.6    Micallef, J.7    Blin, O.8
  • 33
    • 0037622717 scopus 로고    scopus 로고
    • Inhibition of microglial activation attenuates the development but not existing hypersensitivity in a rat model of neuropathy
    • V. Raghavendra, F. Tanga, and J.A. DeLeo Inhibition of microglial activation attenuates the development but not existing hypersensitivity in a rat model of neuropathy J Pharmacol Exp Ther 306 2003 624 630
    • (2003) J Pharmacol Exp Ther , vol.306 , pp. 624-630
    • Raghavendra, V.1    Tanga, F.2    Deleo, J.A.3
  • 34
    • 3242758909 scopus 로고    scopus 로고
    • Complete Freunds adjuvant-induced peripheral inflammation evokes glial activation and proinflammatory cytokine expression in the CNS
    • V. Raghavendra, F.Y. Tanga, and J.A. DeLeo Complete Freunds adjuvant-induced peripheral inflammation evokes glial activation and proinflammatory cytokine expression in the CNS Eur J Neurosci 20 2004 467 473
    • (2004) Eur J Neurosci , vol.20 , pp. 467-473
    • Raghavendra, V.1    Tanga, F.Y.2    Deleo, J.A.3
  • 36
    • 78149357276 scopus 로고    scopus 로고
    • Interactions between the immune and nervous systems in pain
    • K. Ren, and R. Dubner Interactions between the immune and nervous systems in pain Nat Med 16 2010 1267 1276
    • (2010) Nat Med , vol.16 , pp. 1267-1276
    • Ren, K.1    Dubner, R.2
  • 37
    • 3042698916 scopus 로고    scopus 로고
    • Joint cytokine quantification in two rodent arthritis models: Kinetics of expression, correlation of mRNA and protein levels and response to prednisolone treatment
    • I. Rioja, K.A. Bush, J.B. Buckton, M.C. Dickson, and P.F. Life Joint cytokine quantification in two rodent arthritis models: kinetics of expression, correlation of mRNA and protein levels and response to prednisolone treatment Clin Exp Immunol 137 2004 65 73
    • (2004) Clin Exp Immunol , vol.137 , pp. 65-73
    • Rioja, I.1    Bush, K.A.2    Buckton, J.B.3    Dickson, M.C.4    Life, P.F.5
  • 38
    • 57349114132 scopus 로고    scopus 로고
    • Immune system, pain and analgesia
    • M.C. Bushnell, A.I. Basbaum, Academic Press San Diego
    • H.L. Rittner, H. Machelska, and C. Stein Immune system, pain and analgesia M.C. Bushnell, A.I. Basbaum, The senses: a comprehensive reference 2008 Academic Press San Diego 407 428
    • (2008) The Senses: A Comprehensive Reference , pp. 407-428
    • Rittner, H.L.1    Machelska, H.2    Stein, C.3
  • 40
    • 34548610908 scopus 로고    scopus 로고
    • Costorage of BDNF and neuropeptides within individual dense-core vesicles in central and peripheral neurons
    • C. Salio, S. Averill, J.V. Priestley, and A. Merighi Costorage of BDNF and neuropeptides within individual dense-core vesicles in central and peripheral neurons Dev Neurobiol 67 2007 326 338
    • (2007) Dev Neurobiol , vol.67 , pp. 326-338
    • Salio, C.1    Averill, S.2    Priestley, J.V.3    Merighi, A.4
  • 41
    • 67349202612 scopus 로고    scopus 로고
    • Models and mechanisms of hyperalgesia and allodynia
    • J. Sandkuhler Models and mechanisms of hyperalgesia and allodynia Physiol Rev 89 2009 707 758
    • (2009) Physiol Rev , vol.89 , pp. 707-758
    • Sandkuhler, J.1
  • 42
    • 0022341560 scopus 로고
    • Effects of an experimental arthritis on the sensory properties of fine articular afferent units
    • H.G. Schaible, and R.F. Schmidt Effects of an experimental arthritis on the sensory properties of fine articular afferent units J Neurophysiol 54 1985 1109 1122
    • (1985) J Neurophysiol , vol.54 , pp. 1109-1122
    • Schaible, H.G.1    Schmidt, R.F.2
  • 43
    • 0023243573 scopus 로고
    • Enhancement of the responses of ascending tract cells in the cat spinal cord by acute inflammation of the knee joint
    • H.G. Schaible, R.F. Schmidt, and W.D. Willis Enhancement of the responses of ascending tract cells in the cat spinal cord by acute inflammation of the knee joint Exp Brain Res 66 1987 489 499
    • (1987) Exp Brain Res , vol.66 , pp. 489-499
    • Schaible, H.G.1    Schmidt, R.F.2    Willis, W.D.3
  • 44
    • 0032433519 scopus 로고    scopus 로고
    • Treatment of adjustment disorder with anxiety: Efficacy and tolerance of etifoxine in a double-blind controlled study
    • D. Servant, P.L. Graziani, D. Moyse, and P.J. Parquet Treatment of adjustment disorder with anxiety: efficacy and tolerance of etifoxine in a double-blind controlled study Encephale 24 1998 569 574
    • (1998) Encephale , vol.24 , pp. 569-574
    • Servant, D.1    Graziani, P.L.2    Moyse, D.3    Parquet, P.J.4
  • 45
    • 34248573424 scopus 로고    scopus 로고
    • Is functional state of spinal microglia involved in the anti-allodynic and anti-hyperalgesic effects of electroacupuncture in rat model of monoarthritis?
    • S. Shan, M.Y. Qi-Liang, C. Hong, L. Tingting, H. Mei, P. Haili, W. Yan-Qing, Z. Zhi-Qi, and Z. Yu-Qiu Is functional state of spinal microglia involved in the anti-allodynic and anti-hyperalgesic effects of electroacupuncture in rat model of monoarthritis? Neurobiol Dis 26 2007 558 568
    • (2007) Neurobiol Dis , vol.26 , pp. 558-568
    • Shan, S.1    Qi-Liang, M.Y.2    Hong, C.3    Tingting, L.4    Mei, H.5    Haili, P.6    Yan-Qing, W.7    Zhi-Qi, Z.8    Yu-Qiu, Z.9
  • 46
    • 2342646193 scopus 로고    scopus 로고
    • Recent findings on how proinflammatory cytokines cause pain: Peripheral mechanisms in inflammatory and neuropathic hyperalgesia
    • C. Sommer, and M. Kress Recent findings on how proinflammatory cytokines cause pain: peripheral mechanisms in inflammatory and neuropathic hyperalgesia Neurosci Lett 361 2004 184 187
    • (2004) Neurosci Lett , vol.361 , pp. 184-187
    • Sommer, C.1    Kress, M.2
  • 47
    • 34047266975 scopus 로고    scopus 로고
    • New evidence for the involvement of spinal fractalkine receptor in pain facilitation and spinal glial activation in rat model of monoarthritis
    • S. Sun, H. Cao, M. Han, T.T. Li, H.L. Pan, Z.Q. Zhao, and Y.Q. Zhang New evidence for the involvement of spinal fractalkine receptor in pain facilitation and spinal glial activation in rat model of monoarthritis PAIN® 129 2007 64 75
    • (2007) PAIN® , vol.129 , pp. 64-75
    • Sun, S.1    Cao, H.2    Han, M.3    Li, T.T.4    Pan, H.L.5    Zhao, Z.Q.6    Zhang, Y.Q.7
  • 48
    • 0035081365 scopus 로고    scopus 로고
    • Prostaglandins and cyclooxygenases in the spinal cord
    • H. Vanegas, and H.G. Schaible Prostaglandins and cyclooxygenases in the spinal cord Prog Neurobiol 64 2001 327 363
    • (2001) Prog Neurobiol , vol.64 , pp. 327-363
    • Vanegas, H.1    Schaible, H.G.2
  • 49
    • 0035890261 scopus 로고    scopus 로고
    • Spinal prostaglandins are involved in the development but not the maintenance of inflammation-induced spinal hyperexcitability
    • E. Vasquez, K.J. Bar, A. Ebersberger, B. Klein, H. Vanegas, and H.G. Schaible Spinal prostaglandins are involved in the development but not the maintenance of inflammation-induced spinal hyperexcitability J Neurosci 21 2001 9001 9008
    • (2001) J Neurosci , vol.21 , pp. 9001-9008
    • Vasquez, E.1    Bar, K.J.2    Ebersberger, A.3    Klein, B.4    Vanegas, H.5    Schaible, H.G.6
  • 50
    • 0033656015 scopus 로고    scopus 로고
    • The pain of being sick: Implications of immune-to-brain communication for understanding pain
    • L.R. Watkins, and S.F. Maier The pain of being sick: implications of immune-to-brain communication for understanding pain Annu Rev Psychol 51 2000 29 57
    • (2000) Annu Rev Psychol , vol.51 , pp. 29-57
    • Watkins, L.R.1    Maier, S.F.2
  • 51
    • 0030273264 scopus 로고    scopus 로고
    • Characterization of time course of spinal amino acids, citrulline and PGE2 release after carrageenan/kaolin-induced knee joint inflammation: A chronic microdialysis study
    • L.C. Yang, M. Marsala, and T.L. Yaksh Characterization of time course of spinal amino acids, citrulline and PGE2 release after carrageenan/kaolin-induced knee joint inflammation: a chronic microdialysis study PAIN® 67 1996 345 354
    • (1996) PAIN® , vol.67 , pp. 345-354
    • Yang, L.C.1    Marsala, M.2    Yaksh, T.L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.