The CCR4-NOT Complex Mediates Deadenylation and Degradation of Stem Cell mRNAs and Promotes Planarian Stem Cell Differentiation

PLoS Genetics

Volumn 9, Issue 12, 2013, Pages

  Solana, Jordi ^a,b   Gamberi, Chiara ^c,d   Mihaylova, Yuliana ^a,e   Grosswendt, Stefanie ^b   Chen, Chen ^a   Lasko, Paul ^c   Rajewsky, Nikolaus ^b   Aboobaker, A Aziz ^a,e  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^b MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

^c MCGILL UNIVERSITY   (Canada)

^d Gina Cody School of Engineering and Computer Science   (Canada)

^e UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CCR4 NOT COMPLEX; MESSENGER RNA; POLYADENYLIC ACID; REGULATOR PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL METABOLISM; CELL PROLIFERATION; CHEMICAL MODIFICATION; CONTROLLED STUDY; DEADENYLATION; GENE; GENE EXPRESSION; GENE FUNCTION; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN FUNCTION; RNA DEGRADATION; SMED NOT1 GENE; STEM CELL; TRANSCRIPTION REGULATION;

ANIMALS; BACTERIAL PROTEINS; CELL DIFFERENTIATION; CELL PROLIFERATION; GENE EXPRESSION REGULATION, DEVELOPMENTAL; PLANARIANS; REGENERATION; RIBONUCLEASES; RNA INTERFERENCE; RNA STABILITY; RNA, MESSENGER; STEM CELLS;

EID: 84892741340     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1004003     Document Type: Article

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