The essential function of Not1 lies within the Ccr4-Not complex

Journal of Molecular Biology

Volumn 303, Issue 2, 2000, Pages 131-143

  Maillet, Laurent ^a   Tu, Chi ^a   Hong, Young Kwon ^a   Shuster, Elisabeth O ^b   Collart, Martine A ^a  

^a UNIVERSITY OF GENEVA MEDICAL SCHOOL   (Switzerland)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

CCR4; Complex; NOT1; Transcription; Yeast

Indexed keywords

CHEMOKINE RECEPTOR CXCR4;

ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL FUNCTION; CELL VIABILITY; COMPLEX FORMATION; DNA TEMPLATE; GENE EXPRESSION REGULATION; GENE MUTATION; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; SACCHAROMYCES CEREVISIAE; TATA BOX; TRANSCRIPTION REGULATION;

ANIMALIA; SACCHAROMYCES CEREVISIAE;

EID: 0034692875     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.2000.4131     Document Type: Article

References (19)

1. The CCR4 and CAF1 proteins of the CCR4-NOT complex are physically and functionally separated from NOT2
2. Association of distinct yeast Not2 functional domains with components of Gcn5 histone acetylase and Ccr4 transcriptional regulatory complexes
3. A complex containing RNA polymerase II, Paf1p, Cdc73p, Hpr1p, and Ccr4p plays a role in protein kinase C signaling
4. Protein interaction cloning in yeast: Identification of mammalian proteins that react with the leucine zipper of Jun
5. The NOT, SPT3, and MOT1 genes functionally interact to regulate transcription at core promoters
6. CDC39, an essential nuclear protein that negatively regulates transcription and differentially affects the constitutive and inducible HIS3 promoters
7. NOT1(CDC39), NOT2(CDC36), NOT3, and NOT4 encode a global-negative regulator of transcription that differentially affects TATA-element utilization
8. Identification of new genes involved in the regulation of yeast alcohol dehydrogenase II
9. The CCR4 gene from Saccharomyces cerevisiae is required for both nonfermentative and spt-mediated gene expression
10. Identification of a mouse protein whose homolog in Saccharomyces cerevisiae is a component of the CCR4 transcriptional regulatory complex
11. SPT3 interacts with TFIID to allow normal transcription in Saccharomyces cerevisiae
12. Molecular genetics of the RNA polymerase II general transcription machinery
13. Efficient site-directed mutagenesis using uracil-containing DNA
14. Interplay of positive and negative regulators in transcription initiation by RNA polymerase II holoenzyme
15. The TATA binding protein-associated factor yTaf(11)19p functionally interacts with components of the global transcriptional regulator Ccr4-Not complex and physically interacts with the Not5 subunit
16. The NOT proteins are part of the CCR4 transcriptional complex and affect gene expression both positively and negatively
17. Characterization of NOT5 that encodes a new component of the Not protein complex
18. Five SWI/SNF gene products are components of a large multisubunit complex required for transcriptional enhancement
19. Essential functional interactions of SAGA, a Saccharomyces cerevisiae complex of Spt, Ada, and Gcn5 proteins, with the Snf/Swi and Srb/mediator complexes