Identification of genes needed for regeneration, stem cell function, and tissue homeostasis by systematic gene perturbation in planaria

Developmental Cell

Volumn 8, Issue 5, 2005, Pages 635-649

  Reddien, Peter W ^a   Bermange, Adam L ^a,b   Murfitt, Kenneth J ^a   Jennings, Joya R ^a   Sánchez Alvarado, Alejandro ^a  

^a UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^b London Research Institute   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; MESSENGER RNA;

ANIMAL EXPERIMENT; ANTIBODY LABELING; ARTICLE; BLASTEMA; CELL DIVISION; CELL FUNCTION; CELL PROLIFERATION; CONTROLLED STUDY; DNA LIBRARY; DNA TRANSFER; GENE FUNCTION; GENE IDENTIFICATION; GENETIC SCREENING; HOMEOSTASIS; MOLECULAR GENETICS; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN FUNCTION; RNA INTERFERENCE; STEM CELL; TISSUE REGENERATION; TURBELLARIA;

ANIMALS; BODY PATTERNING; CELL DIFFERENTIATION; CONSERVED SEQUENCE; DNA, HELMINTH; GENES, HELMINTH; GENETIC SCREENING; HOMEOSTASIS; PHENOTYPE; PLANARIANS; REGENERATION; RNA INTERFERENCE; STEM CELLS; TERMINOLOGY; WOUND HEALING;

EID: 17844395204     PISSN: 15345807     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.devcel.2005.02.014     Document Type: Article

References (42)

1. A. Adoutte G. Balavoine N. Lartillot O. Lespinet B. Prud'homme and R. de Rosa The new animal phylogeny: Reliability and implications Proc. Natl. Acad. Sci. USA 97 2000 4453-4456
2. C.R. Bardeen and F.H. Baetjer The inhibitive action of the Roentgen rays on regeneration in planarians J. Exp. Zool. 1 1904 191-195
3. A.P. Beltrami L. Barlucchi D. Torella M. Baker F. Limana S. Chimenti H. Kasahara M. Rota E. Musso K. Urbanek et al. Adult cardiac stem cells are multipotent and support myocardial regeneration Cell 114 2003 763-776
4. V. Bennett and A.J. Baines Spectrin and ankyrin-based pathways: Metazoan inventions for integrating cells into tissues Physiol. Rev. 81 2001 1353-1392
5. F. Bergeron R. Leduc and R. Day Subtilase-like pro-protein convertases: from molecular specificity to therapeutic applications J. Mol. Endocrinol. 24 2000 1-22
6. C. Blanpain W.E. Lowry A. Geoghegan L. Polak and E. Fuchs Self-renewal, multipotency, and the existence of two cell populations within an epithelial stem cell niche Cell 118 2004 635-648
7. S. Brenner The genetics of Caenorhabditis elegans Genetics 77 1974 71-94
8. K. Carpenter M. Morita and J. Best Ultrastructure of the photoreceptor of the planarian Dugesia dorotocephala. I. Normal eye Cell Tissue Res. 148 1974 143-158
9. G. Casari M. De Fusco S. Ciarmatori M. Zeviani M. Mora P. Fernandez G. De Michele A. Filla S. Cocozza R. Marconi et al. Spastic paraplegia and OXPHOS impairment caused by mutations in paraplegin, a nuclear-encoded mitochondrial metalloprotease Cell 93 1998 973-983
10. F. Castets T. Rakitina S. Gaillard A. Moqrich M.G. Mattei and A. Monneron Zinedin, SG2NA, and striatin are calmodulin-binding, WD repeat proteins principally expressed in the brain J. Biol. Chem. 275 2000 19970-19977
11. E.M. De Robertis and H. Kuroda Dorsal-ventral patterning and neural induction in Xenopus embryos Annu. Rev. Cell Dev. Biol. 20 2004 285-308
12. W. Driever L. Solnica-Krezel A.F. Schier S.C. Neuhauss J. Malicki D.L. Stemple D.Y. Stainier F. Zwartkruis S. Abdelilah Z. Rangini et al. A genetic screen for mutations affecting embryogenesis in zebrafish Development 123 1996 37-46
13. A. Fire S. Xu M.K. Montgomery S.A. Kostas S.E. Driver and C.C. Mello Potent and specific genetic interference by double-standed RNA in Caenorhabditis elegans Nature 391 1998 806-811
14. A.G. Fraser R.S. Kamath P. Zipperlen M. Martinez-Campos M. Sohrmann and J. Ahringer Functional genomic analysis of C. elegans chromosome I by systematic RNA interference Nature 408 2000 325-330
15. P. Gonczy C. Echeverri K. Oegema A. Coulson S.J. Jones R.R. Copley J. Duperon J. Oegema M. Brehm and E. Cassin Functional genomic analysis of cell division in C. elegans using RNAi of genes on chromosome III Nature 408 2000 331-336
16. P. Haffter M. Granato M. Brand M.C. Mullins M. Hammerschmidt D.A. Kane J. Odenthal F.J. van Eeden Y.J. Jiang C.P. Heisenberg et al. The identification of genes with unique and essential functions in the development of the zebrafish, Danio rerio Development 123 1996 1-36
17. M.J. Hendzel Y. Wei M.A. Mancini A. Van Hooser T. Ranalli B.R. Brinkley D.P. Bazett-Jones and C.D. Allis Mitosis-specific phosphorylation of histone H3 initiates primarily within pericentromeric heterochromatin during G2 and spreads in an ordered fashion coincident with mitotic chromosome condensation Chromosoma 106 1997 348-360
18. O. Hobert Behavioral plasticity in C. elegans: Paradigms, circuits, genes J. Neurobiol. 54 2003 203-223
19. L.H. Hyman The Invertebrates: Platyhelminthes and Rhynchocoela, The acoelomate bilateia, II 1951 McGraw-Hill Book Company New York
20. V. Irish R. Lehmann and M. Akam The Drosophila posterior-group gene nanos functions by repressing hunchback activity Nature 338 1989 646-648
21. T.H. Morgan Experimental studies of the regeneration of Planaria maculata Arch. Entw. Mech. Org. 7 1898 364-397
22. P. Newmark and A. Sánchez Alvarado Bromodeoxyuridine specifically labels the regenerative stem cells of planarians Dev. Biol. 220 2000 142-153
23. P.A. Newmark P.W. Reddien F. Cebria and A. Sánchez Alvarado Ingestion of bacterially expressed double-stranded RNA inhibits gene expression in planarians Proc. Natl. Acad. Sci. USA 100 2003 11861-11865
24. K.M. Nishiguchi M.A. Sandberg A.C. Kooijman K.A. Martemyanov J.W. Pott S.A. Hagstrom V.Y. Arshavsky E.L. Berson and T.P. Dryja Defects in RGS9 or its anchor protein R9AP in patients with slow photoreceptor deactivation Nature 427 2004 75-78
25. C. Nusslein-Volhard and E. Wieschaus Mutations affecting segment number and polarity in Drosophila Nature 287 1980 795-801
26. N.J. Oviedo P.A. Newmark and A. Sánchez Alvarado Allometric scaling and proportion regulation in the freshwater planarian Schmidtea mediterranea Dev. Dyn. 226 2003 326-333
27. J.M. Peters The anaphase-promoting complex: Proteolysis in mitosis and beyond Mol. Cell 9 2002 931-943
28. H. Randolph Observations and experiments on regeneration in planarians Arch. Entw. Mech. Org. 5 1897 352-372
29. P.W. Reddien and A. Sánchez Alvarado Fundamentals of planarian regeneration Annu. Rev. Cell Dev. Biol. 20 2004 725-757
30. F. Sakai K. Agata H. Orii and K. Watanabe Organization and regeneration ability of spontaneous supernumerary eyes in planarians-eye regeneration field and pathway selection by optic nerves Zool. Sci. 17 2000 375-381
31. A. Sánchez Alvarado and P.A. Newmark Double-stranded RNA specifically disrupts gene expression during planarian regeneration Proc. Natl. Acad. Sci. USA 96 1999 5049-5054
32. A. Sánchez Alvarado P.A. Newmark S.M. Robb and R. Juste The Schmidtea mediterranea database as a molecular resource for studying platyhelminthes, stem cells and regeneration Development 129 2002 5659-5665
33. A. Spradling D. Drummond-Barbosa and T. Kai Stem cells find their niche Nature 414 2001 98-104
34. P. ten Dijke and C.S. Hill New insights into TGF-beta-Smad signalling Trends Biochem. Sci. 29 2004 265-273
35. L. Timmons D.L. Court and A. Fire Ingestion of bacterially expressed dsRNAs can produce specific and potent genetic interference in Caenorhabditis elegans Gene 263 2001 103-112
36. N. Uchida D.W. Buck D. He M.J. Reitsma M. Masek T.V. Phan A.S. Tsukamoto F.H. Gage and I.L. Weissman Direct isolation of human central nervous system stem cells Proc. Natl. Acad. Sci. USA 97 2000 14720-14725
37. A.M. Weaver M.E. Young W.L. Lee and J.A. Cooper Integration of signals to the Arp2/3 complex Curr. Opin. Cell Biol. 15 2003 23-30
38. I.L. Weissman Stem cells: Units of development, units of regeneration, and units in evolution Cell 100 2000 157-168
39. I.L. Weissman D.J. Anderson and F. Gage Stem and progenitor cells: origins, phenotypes, lineage commitments, and transdifferentiations Annu. Rev. Cell Dev. Biol. 17 2001 387-403
40. D.M. Willis A.P. Loewy N. Charlton-Kachigian J.S. Shao D.M. Ornitz and D.A. Towler Regulation of osteocalcin gene expression by a novel Ku antigen transcription factor complex J. Biol. Chem. 277 2002 37280-37291
41. J. Yang X. Liu G. Yue M. Adamian O. Bulgakov T. and Li Rootletin, a novel coiled-coil protein, is a structural component of the ciliary rootlet J. Cell Biol. 159 2002 431-440
42. P.S. Zammit J.P. Golding Y. Nagata V. Hudon T.A. Partridge and J.R. Beauchamp Muscle satellite cells adopt divergent fates: A mechanism for self-renewal? J. Cell Biol. 166 2004 347-357