Improving permeability and oral absorption of mangiferin by phospholipid complexation

Fitoterapia

Volumn 93, Issue , 2014, Pages 54-61

  Ma, Hequn ^a   Chen, Hongming ^a   Sun, Le ^a   Tong, Lijin ^a   Zhang, Tianhong ^a  

^a SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

Intestinal absorption; Mangiferin; Pharmacokinetics; Phospholipid complex; Physicochemical properties

Indexed keywords

LIPOID E 80; MANGIFERIN; MANGIFERIN PHOSPHOLIPID COMPLEX; OCTANOL; PHOSPHOLIPID; UNCLASSIFIED DRUG; WATER; XANTHONE DERIVATIVE;

ABSORPTION SPECTROSCOPY; ANIMAL EXPERIMENT; ANIMAL TISSUE; AQUEOUS SOLUTION; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DIFFERENTIAL SCANNING CALORIMETRY; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG ELIMINATION; DRUG HALF LIFE; DRUG PENETRATION; DRUG SOLUBILITY; IN VITRO STUDY; INFRARED SPECTROSCOPY; INTESTINE ABSORPTION; INTESTINE MUCOSA PERMEABILITY; INTESTINE PERFUSION; MALE; MAXIMUM PLASMA CONCENTRATION; NONHUMAN; PARTITION COEFFICIENT; PHYSICAL CHEMISTRY; PLASMA CONCENTRATION-TIME CURVE; PRIORITY JOURNAL; RAT; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SCANNING ELECTRON MICROSCOPY; SINGLE DRUG DOSE; TIME TO MAXIMUM PLASMA CONCENTRATION; ANIMAL; BIOAVAILABILITY; CHEMISTRY; DRUG FORMULATION; INFRARED SPECTROPHOTOMETRY; ORAL DRUG ADMINISTRATION; PERMEABILITY; PHYTOTHERAPY; RANDOMIZATION; SOLUBILITY; SPRAGUE DAWLEY RAT;

ADMINISTRATION, ORAL; ANIMALS; BIOLOGICAL AVAILABILITY; CALORIMETRY, DIFFERENTIAL SCANNING; DRUG COMPOUNDING; INTESTINAL ABSORPTION; MALE; MICROSCOPY, ELECTRON, SCANNING; PERMEABILITY; PHOSPHOLIPIDS; PHYTOTHERAPY; RANDOM ALLOCATION; RATS; RATS, SPRAGUE-DAWLEY; SOLUBILITY; SPECTROPHOTOMETRY, INFRARED; XANTHONES;

EID: 84892710938     PISSN: 0367326X     EISSN: 18736971     Source Type: Journal    
DOI: 10.1016/j.fitote.2013.10.016     Document Type: Article

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