Reach task-associated excitatory overdrive of motor cortical neurons following infusion with ALS-CSF

Journal of Neural Transmission

Volumn 121, Issue 1, 2014, Pages 49-58

  Sankaranarayani, R ^a   Raghavan, Mohan ^b   Nalini, A ^a   Laxmi, T R ^a   Raju, T R ^a  

^a NATIONAL INSTITUTE OF MENTAL HEALTH AND NEUROSCIENCES   (India)

^b INDIAN INSTITUTE OF SCIENCE   (India)

Author keywords

Amyotrophic lateral sclerosis; CSF infusion; Firing rate; Rat motor cortex; Reach to grasp task; Single unit activity

Indexed keywords

AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN CELL; BRAIN VENTRICLE; CEREBROSPINAL FLUID; CONTROLLED STUDY; HISTOLOGY; INDEX OF FIRING RATE CHANGE; MALE; MOTONEURON; MOTOR CORTEX; MOTOR DYSFUNCTION; NERVE CELL EXCITABILITY; NERVOUS SYSTEM PARAMETERS; NONHUMAN; PERI REACH FIRING RATE CHANGE; PRIORITY JOURNAL; PYRAMIDAL NERVE CELL; RAT; SINGLE UNIT ACTIVITY; TASK PERFORMANCE;

ACTION POTENTIALS; AMYOTROPHIC LATERAL SCLEROSIS; ANIMALS; CEREBROSPINAL FLUID; HAND STRENGTH; HUMANS; MALE; MOTOR CORTEX; MOTOR NEURONS; RATS; RATS, WISTAR;

EID: 84892678549     PISSN: 03009564     EISSN: 14351463     Source Type: Journal    
DOI: 10.1007/s00702-013-1071-4     Document Type: Article

References (30)

1. Alaverdashvili M, Whishaw IQ (2008) Motor cortex stroke impairs individual digit movement in skilled reaching by the rat. Eur J Neurosci 28:311-322
2. Beers DR, Ho BK, Siklos L, Alexianu ME, Mosier DR, Mohamed AH, Otsuka Y, Kozovska ME, McAlhany RE, Smith RG, Appel SH (2001) Parvalbumin overexpression alters immune-mediated increases in intracellular calcium, and delays disease onset in a transgenic model of familial amyotrophic lateral sclerosis. J Neurochem 79:499-509 (Pubitemid 33029923)
3. Bland BH, Oddie SD (2001) Theta band oscillation and synchrony in the hippocampal formation and associated structures: the case for its role in sensorimotor integration. Behav Brain Res 127:119-136 (Pubitemid 33069358)
4. Buzsaki G (2004) Large-scale recording of neuronal ensembles. Nat Neurosci 7:446-451 (Pubitemid 38544574)
5. Donoghue JP, Wise SP (1982) The motor cortex of the rat: cytoarchitecture and micro stimulation mapping. J Comp Neurol 212:76-88 (Pubitemid 13208310)
6. Fromm GH, Bond HW (1964) Slow changes in the electrocorticogram and the activity of cortical neurons. Electroencephalogr Clin Neurophysiol 17:520-523
7. Goldberg JA, Rokni U, Boraud T, Vaadia E, Bergman H (2004) Spike synchronization in the cortex/basal-ganglia networks of Parkinsonian primates reflects global dynamics of the local field potentials. J Neurosci 24:6003-6010 (Pubitemid 38859396)
8. Gunasekaran R, Narayani RS, Vijayalakshmi K, Alladi PA, Shobha K, Nalini A, Sathyaprabha TN, Raju TR (2009) Exposure to cerebrospinal fluid of sporadic amyotrophic lateral sclerosis patients alters Nav1.6 and Kv1.6 channel expression in rat spinal motor neurons. Brain Res 1255:170-179
9. Kew JJ, Leigh PN, Playford ED, Passingham RE, Goldstein LH, Frackowiak RS, Brooks DJ (1993) Cortical function in amyotrophic lateral sclerosis. A positron emission tomography study. Brain 116(Pt 3):655-680 (Pubitemid 23203643)
10. Konrad C, Henningsen H, Bremer J, Mock B, Deppe M, Buchinger C, Turski P, Knecht S, Brooks B (2002) Pattern of cortical reorganization in amyotrophic lateral sclerosis: a functional magnetic resonance imaging study. Exp Brain Res 143:51-56 (Pubitemid 34516358)
11. Kuo JJ, Siddique T, Fu R, Heckman CJ (2005) Increased persistent Na (+) current and its effect on excitability in motoneurons cultured from mutant SOD1 mice. J Physiol 563:843-854 (Pubitemid 40425599)
12. Maekawa S, Al Sarraj S, Kibble M, Landau S, Parnavelas J, Cotter D, Everall I, Leigh PN (2004) Cortical selective vulnerability in motor neuron disease: a morphometric study. Brain 127:1237-1251 (Pubitemid 38745505)
13. Moyanova S, Kirov R, Kortenska L (2003) Multi-unit activity suppression and sensorimotor deficits after endothelin-1-induced middle cerebral artery occlusion in conscious rats. J Neurol Sci 212:59-67 (Pubitemid 36693966)
14. Neafsey EJ, Bold EL, Haas G, Hurley-Gius KM, Quirk G, Sievert CF, Terreberry RR (1986) The organization of the rat motor cortex: a micro stimulation mapping study. Brain Res 396:77-96 (Pubitemid 16126208)
15. Nihei K, McKee AC, Kowall NW (1993) Patterns of neuronal degeneration in the motor cortex of amyotrophic lateral sclerosis patients. Acta Neuropathol 86:55-64 (Pubitemid 23249074)
16. Paxinos G, Watson C (1986) The rat brain in stereotaxic coordinates, 2nd edn. Academic Press, Sydney, Australia
17. Petri S, Kiaei M, Wille E, Calingasan NY, Flint BM (2006a) Loss of Fas ligand-function improves survival in G93A-transgenic ALS mice. J Neurol Sci 251:44-49 (Pubitemid 44792137)
18. Petri S, Kollewe K, Grothe C, Hori A, Dengler R, Bufler J, Krampfl K (2006b) GABA (A)-receptor mRNA expression in the prefrontal and temporal cortex of ALS patients. J Neurol Sci 250:124-132 (Pubitemid 44665945)
19. Pieri M, Carunchio I, Curcio L, Mercuri NB, Zona C (2009) Increased persistent sodium current determines cortical hyperexcitability in a genetic model of amyotrophic lateral sclerosis. Exp Neurol 215:368-379
20. Sankaranarayani R, Nalini A, Rao LT, Raju TR (2010) Altered neuronal activities in the motor cortex with impaired motor performance in adult rats observed after infusion of cerebrospinal fluid from amyotrophic lateral sclerosis patients. Behav Brain Res 206:109-119
21. Schoenfeld MA, Tempelmann C, Gaul C, Kuhnel GR, Duzel E, Hopf JM, Feistner H, Zierz S, Heinze HJ, Vielhaber S (2005) Functional motor compensation in amyotrophic lateral sclerosis. J Neurol 252:944-952 (Pubitemid 41186966)
22. Shahani N, Nalini A, Gourie-Devi M, Raju TR (1998) Reactive astrogliosis in neonatal rat spinal cord after exposure to cerebrospinal fluid from patients with amyotrophic lateral sclerosis. Exp Neurol 149:295-298 (Pubitemid 28091039)
23. Turner MR, Kiernan MC, Leigh PN, Talbot K (2009) Biomarkers in amyotrophic lateral sclerosis. Lan Neurol 8:94-109
24. Vijayalakshmi K, Alladi PA, Sathyaprabha TN, Subramaniam JR, Nalini A, Raju TR (2009) Cerebrospinal fluid from sporadic amyotrophic lateral sclerosis patients induces degeneration of a cultured motor neuron cell line. Brain Res 1263:122-133
25. Wadhwa S (2003) Quantitative stereology: the use of camera lucida for counting neurons by physical dissector method in chick brainstem auditory nuclei. J Postgrad Med 49:376-378 (Pubitemid 38714084)
26. Whishaw IQ, Pellis SM, Gorny BP, Pellis VC (1991) The impairments in reaching and the movements of compensation in rats with motor cortex lesions: an endpoint, videorecording, and movement notation analysis. Behav Brain Res 42(1):77-91
27. Zanette G, Tamburin S, Manganotti P, Refatti N, Forgione A, Rizzuto N (2002) Different mechanisms contribute to motor cortex hyperexcitability in amyotrophic lateral sclerosis. Clin Neurophysiol 113:1688-1697 (Pubitemid 35335457)
28. Zang DW, Cheema SS (2002) Degeneration of corticospinal and bulbospinal systems in the superoxide dismutase 1(G93A G1H) transgenic mouse model of familial amyotrophic lateral sclerosis. Neurosci Lett 332:99-102 (Pubitemid 35217850)
29. Zona C, Ferri A, Gabbianelli R, Mercuri NB, Bernardi G, Rotilio G, Carri MT (1998) Voltage-activated sodium currents in a cell line expressing a Cu, Zn superoxide dismutase typical of familial ALS. Neuro Report 9:3515-3518 (Pubitemid 28566140)
30. Zona C, Pieri M, Carunchio I (2006) Voltage-dependent sodium channels in spinal cord motor neurons display rapid recovery from fast inactivation in a mouse model of amyotrophic lateral sclerosis. J Neurophysiol 96:3314-3322 (Pubitemid 44837875)