Emulsification using highly hydrophilic surfactants improves the absorption of orally administered coenzyme Q10

Biological and Pharmaceutical Bulletin

Volumn 36, Issue 12, 2013, Pages 2012-2017

  Sato, Yuki ^a   Mutoh, Hanami ^a   Suzuki, Mika ^a   Takekuma, Yoh ^a   Iseki, Ken ^a   Sugawara, Mitsuru ^a  

^a HOKKAIDO UNIVERSITY   (Japan)

Author keywords

Absorption; Bile; Coenzyme Q10; Emulsion; Intestine; Lutein

Indexed keywords

POLYOXYETHYLENE SORBITAN TRISTEARATE; POLYSORBATE 20; POLYSORBATE 80; SORBITAN LAURATE; SURFACTANT; TWEEN 65; UBIDECARENONE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; BILE; CONTROLLED STUDY; DRUG ABSORPTION; DRUG BLOOD LEVEL; DRUG FORMULATION; EMULSION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MALE; NONHUMAN; RAT; SUSPENSION;

ADMINISTRATION, ORAL; ANIMALS; BIOLOGICAL AVAILABILITY; EMULSIONS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; INTESTINAL ABSORPTION; MALE; METHYLCELLULOSE; RATS; RATS, WISTAR; SURFACE-ACTIVE AGENTS; SUSPENSIONS; UBIQUINONE;

EID: 84892606915     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.b13-00447     Document Type: Article

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