Hypothalamic GPR40 signaling activated by free long chain fatty acids suppresses CFA-induced inflammatory chronic pain

PLoS ONE

Volumn 8, Issue 12, 2013, Pages

  Nakamoto, Kazuo ^a   Nishinaka, Takashi ^a   Sato, Naoya ^a   Mankura, Mitsumasa ^b   Koyama, Yutaka ^c   Kasuya, Fumiyo ^a   Tokuyama, Shogo ^a  

^a KOBE GAKUIN UNIVERSITY   (Japan)

^b Bizen Chemical Co Ltd   (Japan)

^c OSAKA OHTANI UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BETA ENDORPHIN; DOCOSAHEXAENOIC ACID; FLAVOPIRIDOL; FREUND ADJUVANT; G PROTEIN COUPLED RECEPTOR 40; GLIAL FIBRILLARY ACIDIC PROTEIN; LONG CHAIN FATTY ACID; NEURON SPECIFIC NUCLEAR PROTEIN; PROOPIOMELANOCORTIN; PROTEIN C FOS;

ALLODYNIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARCUATE NUCLEUS; ARTICLE; ASTROCYTE; BRAIN TISSUE; CHRONIC PAIN; CONTROLLED STUDY; HYPERALGESIA; HYPERPLASIA; HYPOTHALAMUS; IMMUNOFLUORESCENCE; INFLAMMATORY PAIN; MALE; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

ANIMALS; ARCUATE NUCLEUS; ASTROCYTES; BENZOATES; BETA-ENDORPHIN; CHRONIC PAIN; DISEASE MODELS, ANIMAL; DOCOSAHEXAENOIC ACIDS; FLAVONOIDS; FREUND'S ADJUVANT; GENE EXPRESSION; HYPERALGESIA; INJECTIONS, INTRAVENTRICULAR; MALE; METHYLAMINES; MICE; NERVE TISSUE PROTEINS; NEUROGLIA; NUCLEAR PROTEINS; PAIN MANAGEMENT; PIPERIDINES; PRO-OPIOMELANOCORTIN; PROPIONATES; PYRIMIDINES; RECEPTORS, G-PROTEIN-COUPLED; SIGNAL TRANSDUCTION; TIME FACTORS;

EID: 84892597440     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0081563     Document Type: Article

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