Infusion of Trx-1-overexpressing hucMSC prolongs the survival of acutely irradiated NOD/SCID mice by decreasing excessive inflammatory injury

PLoS ONE

Volumn 8, Issue 11, 2013, Pages

  Hu, JiangWei ^a   Yang, ZaiLiang ^a,b   Wang, Jun ^a   Tang, YongYong ^a   Liu, Hao ^a   Zhang, Bin ^a   Chen, Hu ^a  

^a BEIJING INSTITUTE OF MICROBIOLOGY AND EPIDEMIOLOGY   (China)

^b THIRD MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOVIRUS VECTOR; HYDROGEN PEROXIDE; THIOREDOXIN 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; COBALT THERAPY; CONTROLLED STUDY; ERYTHROPOIESIS; GENE OVEREXPRESSION; HEMATOPOIETIC STEM CELL; HEMOLYSIS; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATION; LIPID PEROXIDATION; MALE; MESENCHYMAL STEM CELL TRANSPLANTATION; MOUSE; NONHUMAN; OXIDATION; RADIATION EXPOSURE; RADIATION INJURY; RADIATION PROTECTION; SURVIVAL TIME; TRX 1 GENE; UMBILICAL CORD; VIRAL GENE THERAPY;

ACUTE RADIATION SYNDROME; ADENOVIRIDAE; ANIMALS; ANTIOXIDANTS; BONE MARROW; CELL- AND TISSUE-BASED THERAPY; FETAL BLOOD; GENETIC THERAPY; GENETIC VECTORS; INFLAMMATION; INTESTINES; LIVER; MALE; MESENCHYMAL STEM CELL TRANSPLANTATION; MESENCHYMAL STROMAL CELLS; MICE; MICE, INBRED NOD; MICE, SCID; OXIDATION-REDUCTION; SURVIVAL ANALYSIS; THIOREDOXINS; TRANSGENES; WHOLE-BODY IRRADIATION;

EID: 84892576947     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0078227     Document Type: Article

References (56)

1. Tura II, Veress K, GunalpP B, Souchkevitch G (2004) Medical response to radiation incidents and radio nuclear threats. BMJ 328 (7439): 568-572.
2. Meineke V, Fliedner TM (2005) Radiation-induced multi-organ involvement and failure: challenges for radiation accident medical management and future research. BJR Suppl 27:196-200.
3. Hirama T, Tanosaki S, Kandatsu S, Kuroiwa N, Kamada T, et al. (2003) Initial medical management of patient severely irradiated in the Tokai-mura criticality accident. BRJ. Radiol 76(904): 246-253.
4. Arora R, Gupta D, Chawla R, Sagar R, Sharma A, et al. (2005) Radioprotection by Plant Products: Present Status and Future Prospect. Phytother Res 19(1): 1-22.
5. Srinivasan M, Sudheer AR, Pillai KR, Kumar PR, Sudhakaran PR, et al. (2007) Lycopene as a natural protector against c-radiation induced DNA damage, lipid peroxidation and antioxidant status in primary culture of isolated rat hepatocytes in vitro. Biochimica et Biophysica Acta 1770(4): 659-665.
6. Hosseinimehr SJ (2007) Trends in the Development of Radioprotective agent. Drug Discovery Today 12(19/20): 794-805.
7. Valey-Allanore L, Poulalhon N, Fagot JP, Sekula P, Davidovici B, et al. (2008) Stevens-Johnson syndrome and toxic epidermal necrolysis induced by amifostine during head and neck radiotherapy. Radiother Oncol 87(2): 300-303.
8. Kuter DJ (2010) Biology and chemistry of thrombopoietic agents. Semin Hematol 47: 243-248.
9. Fliedner TM, Dorr H, Meineke V (2005) Multi-organ involvement as a pathogenetic principle of the radiation syndromes: a study involving 110 case histories documented in SEARCH and classified as the bases of haematopoietic indicators of effect. BJR Suppl 27: 1-8.
10. Nakamura H. (2005) Thioredoxin and its related molecules: update 2005. Antioxidants & Redox Signaling 7(5-6): 823-81.
11. Holmgren A (1995) Thioredox in structure and mechanism-conformationa-l changes on oxidation of the active-site sulfhydryls to a disulfide. Structure 3(3): 239-431.
12. Laurent TC, Moore EC, Reichard P (1964) Enzymatic synthesis of deoxyribonucleotides. IV. Isolation and characterization of thioredoxin, the hydrogen donor from Escherichia coli B. J Biol Chem 239: 3436-3444.
13. Nordberg J, Arnér ES (2001) Reactive oxygen species, antioxidants, and the mammalian thioredoxin system. Free Radic Biol Med 31(11): 1287-1312.
14. Gasdaska JR, Berggren M, Powis G (1995) Cell growth stimulation by the redox protein thioredoxin occurs by a novel helper mechanism. Cell Growth Differ 6(12): 1643-1650.
15. Kondo N, Ishii Y, Kwon YW, Tanito M, Horita H, et al. (2004) Redox-sensing release of human thioredoxin, from t lymphocytes with negative feedback loops. J immunol 172(1): 442-448.
16. Saitoh M, Nishitoh H, Fujii M, Takeda K, Tobiume K, et al. (1998) Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1. EMBO J 17(9): 2596-2606.
17. Andoh T, Chock PB, Chiueh CC (2002) The role of thioredox in in protection against oxidative stress - induced apoptosis in SH-SY5Y cells. J Biol Chem 277(12): 9655-9660.
18. Nakamura T, Hoshino Y, Yamada A, Teratani A, Furukawa S, et al. (2007) Recombinant human thioredoxin-1 becomes oxidized in circulation and suppresses bleomycin-induced neutrophil recruitment in the rat airway. Free Radical Research 41 (10): 1089-11981.
19. Tamaki H, Nakamura H, Nishio A, Nakase H, Ueno S, et al. (2006) Human thioredoxin-1 ameliorates experimental murine colitis in association with suppressed m acrophage inhibitory factor production. Gastroenterology 131(4): 1110-1211.
20. Inomata Y, Tanihara H, Tanito M, Okuyama H, Hoshino Y, et al. (2008) Suppression of choroidal neovascularization by thioredoxin-1 via interaction with complement factor. Invest Ophthalmol Vis Sci 49 (11): 5118-251.
21. Powis G, Montfort WR (2001) Properties and biological activities of thioredoxins. Annu Rev Pharmacol Toxicol 41: 261-295
22. Go YM, Ziegler TR, Johnson JM, Gu L, Hansen JM, et al. (2007) Selective protection of nuclear thioredoxin-1 and glutathione redox systems against oxidation during glucose and glutamine deficiency in human colonic epithelial cells. Free Radic Biol Med 42(3): 363-370.
23. Nakamura H (2008) Extracellular functions of thioredoxin. Novartis Found Symp 291(1): 184-92, 192-5, 221-41.
24. Powis G, Oblong JE, Gasdaska PY, Berggren M, Hill SR, et al. (1994) The thioredox in/thioredoxin reductase redox system and control of cell growth. Oncol Res 6(10-11): 539-441.
25. Nakamura H, Matsuda M, Furuke K, Kitaoka Y, Iwata S, et al. (1994) Adult T cell leukemia-derived factor/human thioredox in protects endothelialf-2 cell injury caused by activated neutrophils or hydrogen peroxide. Immunol Lett 42(1-2): 75-801.
26. Kondo N, Ishii Y, Kwon YW, Tanito M, Horita H, et al. (2004) Redox-sensing release of human thioredox in from t lymphocytes with negative feedback loops. J Immunol 172 (1): 442-81.
27. Minguell JJ, Erices A, Conget P (2001) Mesenchymal stem cells. Exp Biol Med 226(6): 507-520.
28. Le Blanc K, Pittenger M (2005) Mesenchymal stem cells: progress toward promise. Cytotherapy 7(1): 36-45.
29. Sharma M, Afrin F, Satija N, Tripathi RP, Gangenahalli GU (2011) Stromal-derived factor-1/CXCR4 signaling: indispensable role in homing and engraftment of hematopoietic stem cells in bone marrow. Stem Cells Dev; 20(6): 933-946.
30. Besse A, Trimoreau F, Praloran V, Denizot Y (2000) Effect of cytokines and growth factors on the macrophage colony-stimulating factor secretion by human bone marrow stromal cells. Cytokine 12(5): 522-525.
31. Tmyer DL, Weiss ML (2008) Wharton's jerlly -derived cells are a primitive stromal cell population. Stem Cells 26(3):591-9
32. Kestendjieva S, Kyurkchiev D, Tsvetkova G, Mehandjiev T, Dimitrov A, et al. (2008) Characterization of mesenchymal stem cells isolated from the human umbilicaI cord. Cell Biol Int 32(7): 724-732.
33. Lu LL, Liu YJ, Yang SG, Zhao QJ, Wang X, et al. (2006) Isolation and characterization of human umbilical cord mesenchymal stem cells with hematopoiesis-supportive function and other potentials. Haematologica 91:1017-1026.
34. Dominici M, Le Blanc K, Mueller I, Slaper-Cortenbach I, Marini F, et al. (2006) Minimal criteria for defining multipotent mesenchymal stromal cells. The international society for cellular therapy position statement. Cytotherapy 8(4): 315-317.
35. Justesen J, Stenderup K, Ebbesen EN, Mosekilde L, Steiniche T, et al. (2001) Adipocyte tissue volume in bone marrow is increased with aging and inpatients with osteoporosis. Biogerontology 2(3): 165-171.
36. Underwood S, Foster M, Raeburn D, Bottoms S, Karlsson JA (1995) Time-course of antigen-induced airway inflammation in the guinea-pig and its relationship to airway hyperresponsiveness. Eur Respir J 8(12): 2104-2113.
37. Ishak K, Baptista A, Bianchi L, Callea F, De Groote J, et al. (1995) Histological grading and staging of chronic hepatitis. Hepatol 22(6): 696-699.
38. Obermeier F, Dunger N, Strauch UG, Grunwald N, Herfarth H, et al. (2003) Contrasting activity of cytosin-guanosin dinucleotide oligonucleotides in mice with experimental colitis. Clin Exp Immunol 134(2):217-224.
39. Sak A, Stuschke M, Wurm R, Budach V (2000) Protection of DNA from radiation-induced double-strand breaks: influence of replication and nuclear proteins. Int J Radiat Biol 76(6): 749-756.
40. Lomax ME, Gulston MK, O'Neill P (2002) Chemical aspects of clustered DNA damage induction by ionising radiation. Radiat Prot Dosim 99(1-4): 63-68.
41. Lorimore SA, Coates PJ, Wright EG (2003) Radiation-induced genomic instability and bystander effects: inter-related nontargeted effects of exposure to ionizing radiation. Oncogene 22(45): 7058-7069.
42. Kyrkanides S, Moore AH, Olschowka JA, Daeschner JC, Williams JP, et al. (2002) Cyclooxygenase-2 Modulates Brain Inflammalion-related Gene Expression in Central Nervous System Radiation Injury. Mol. Brain Res 4(2):159.
43. Rübe CE, Wilfert F, Palm J, König J, Burdak-Rothkamm S, et al. (2004) Irradiation induces a biphasic expression of pro-inflammatory cytokines in the lung. Strahlenther Onkol 180(7): 442-448.
44. Kucerova L, Matuskova M, Pastorakova A, Tyciakova S, Jakubikova J, et al. (2008) Cytosine deaminase expressing human mesenchymal stem cells mediated tumour regression in melanoma bearing mice. J Gene Med 10(10): 1071-1082.
45. Kucerova L, Altanerova V, Matuskova M, Tyciakova S, Altaner C (2007) Adipose tissue-derived human mesenchymal stem cells mediated prodrug cancer gene therapy. Cancer Res 67(13): 6304-6313.
46. Cavarretta IT, Altanerova V, Matuskova M, Kucerova L, Culig Z, et al. (2010) Adipose tissue-derived mesenchymal stem cells expressing prodrug-converting enzyme inhibit human prostate tumor growth. Mol Ther 18(1): 223-231.
47. Kidd S, Caldwell L, Dietrich M, Samudio I, Spaeth EL, et al. (2010) Mesenchymal stromal cells alone or expressing interferonbeta suppress pancreatic tumors in vivo, an effect countered by anti-inflammatory treatment. Cytotherapy 12(5): 615-625.
48. Sato H, Kuwashima N, Sakaida T, Hatano M, Dusak JE, et al. (2005) Epidermal growth factor receptor-transfected bone marrow stromal cells exhibit enhanced migratory response and therapeutic potential against murine brain tumors. Cancer Gene Ther 12(9): 757-768.
49. Ren C, Kumar S, Chanda D, Kallman L, Chen J, et al. (2008) Cancer gene therapy using mesenchymal stem cells expressing interferon-beta in a mouse prostate cancer lung metastasis model. Gene Ther 15(21): 1446-1453.
50. Xin H, Kanehira M, Mizuguchi H, Hayakawa T, Kikuchi T, et al. (2007) Targeted delivery of CX3CL1 to multiple lung tumors by mesenchymal stem cells. Stem Cells 25(7): 1618-1626.
51. Kurozumi K, Nakamura K, Tamiya T, Kawano Y, Kobune M, et al. (2004) BDNF gene-modified mesenchymal stem cells promote functional recovery and reduce infarct size in the rat middle cerebral artery occlusion model. Mol Ther 9(2): 189-197.
52. Dainiak N (2002) Hematologic consequences of exposure to ionizing radiation. Exp Hematol 30(6):513-528.
53. Fliedner TM, Friesecke I, Beyrer K (2001) Medical management of radiation accidents: Manual on the acute radiation syndrome. Oxford: British Institute of Radiology 18.
54. Takamiya M, Haider KH, Ashraf M (2011) Identification and characterization of a novel multipotent sub-population of sca-1 cardiac progenitor cells for myocardial regeneration. PLoS One 6(9): e25265.
55. Xia S, Guo Z, Xu X, Yi H, Wang Q, et al. (2008) Hepatic microenvironment programs hematopoietic progenitor differentiation into regulatory dendritic cells, maintaining liver tolerance. Blood 112(8): 3175-3185.
56. Okada S, Nakauchi H, Nagayoshi K, Nishikawa S, Miura Y, et al. (1992) In vivo and in vitro stem cell function of c-kit- and sca-1- positive murine hematopoietic cells. Blood 80(12): 3044-3050.