메뉴 건너뛰기




Volumn 7, Issue , 2014, Pages 117-134

Therapeutic targeting of Neu1 sialidase with oseltamivir phosphate (Tamiflu®) disables cancer cell survival in human pancreatic cancer with acquired chemoresistance

Author keywords

Cancer cell survival; Chemoresistance; Human pancreatic cancer; PANC1 cell lines

Indexed keywords

CISPLATIN; GEMCITABINE; NERVE CELL ADHESION MOLECULE; NEUL SIALIDASE; OSELTAMIVIR; SIALIDASE; UNCLASSIFIED DRUG; UVOMORULIN; VASCULAR ENDOTHELIAL CADHERIN;

EID: 84892538604     PISSN: 11786930     EISSN: None     Source Type: Journal    
DOI: 10.2147/OTT.S55344     Document Type: Article
Times cited : (53)

References (72)
  • 1
    • 4544267592 scopus 로고    scopus 로고
    • Selenoprotein P, as a predictor for evaluating gemcitabine resistance in human pancreatic cancer cells
    • Maehara S, Tanaka S, Shimada M, etal. Selenoprotein P, as a predictor for evaluating gemcitabine resistance in human pancreatic cancer cells. Int J Cancer. 2004;112(2):184-189.
    • (2004) Int J Cancer. , vol.112 , Issue.2 , pp. 184-189
    • Maehara, S.1    Tanaka, S.2    Shimada, M.3
  • 2
    • 36349006961 scopus 로고    scopus 로고
    • Development and characterization of gemcitabine-resistant pancreatic tumor cells
    • Shah AN, Summy JM, Zhang J, Park SI, Parikh NU, Gallick GE. Development and characterization of gemcitabine-resistant pancreatic tumor cells. Ann Surg Oncol. 2007;14(12):3629-3637.
    • (2007) Ann Surg Oncol. , vol.14 , Issue.12 , pp. 3629-3637
    • Shah, A.N.1    Summy, J.M.2    Zhang, J.3    Park, S.I.4    Parikh, N.U.5    Gallick, G.E.6
  • 3
    • 65649095142 scopus 로고    scopus 로고
    • Side population of pancreatic cancer cells predominates in TGF-beta-mediated epithelial to mesenchymal transition and invasion
    • Kabashima A, Higuchi H, Takaishi H, etal. Side population of pancreatic cancer cells predominates in TGF-beta-mediated epithelial to mesenchymal transition and invasion. Int J Cancer. 2009;124(12):2771-2779.
    • (2009) Int J Cancer. , vol.124 , Issue.12 , pp. 2771-2779
    • Kabashima, A.1    Higuchi, H.2    Takaishi, H.3
  • 4
    • 40849102700 scopus 로고    scopus 로고
    • Activity of lapatinib a novel HER2 and EGFR dual kinase inhibitor in human endometrial cancer cells
    • Konecny GE, Venkatesan N, Yang G, etal. Activity of lapatinib a novel HER2 and EGFR dual kinase inhibitor in human endometrial cancer cells. Br J Cancer. 2008;98(6):1076-1084.
    • (2008) Br J Cancer. , vol.98 , Issue.6 , pp. 1076-1084
    • Konecny, G.E.1    Venkatesan, N.2    Yang, G.3
  • 5
    • 84881075538 scopus 로고    scopus 로고
    • The role of epithelial-mesenchymal transition programming in invasion and metastasis: A clinical perspective
    • Creighton CJ, Gibbons DL, Kurie JM. The role of epithelial-mesenchymal transition programming in invasion and metastasis: a clinical perspective. Cancer Manag Res. 2013;5:187-195.
    • (2013) Cancer Manag Res. , vol.5 , pp. 187-195
    • Creighton, C.J.1    Gibbons, D.L.2    Kurie, J.M.3
  • 6
    • 67650999217 scopus 로고    scopus 로고
    • Epithelial to transition contributes to drug resistance in pancreatic cancer
    • Arumugam T, Ramachandran V, Fournier KF, etal. Epithelial to transition contributes to drug resistance in pancreatic cancer. Cancer Res. 2009;69(14):5820-5828.
    • (2009) Cancer Res. , vol.69 , Issue.14 , pp. 5820-5828
    • Arumugam, T.1    Ramachandran, V.2    Fournier, K.F.3
  • 7
    • 33847327128 scopus 로고    scopus 로고
    • Chronic oxaliplatin resistance induces epithelial-to-mesenchymal transition in colorectal cancer cell lines
    • Yang AD, Fan F, Camp ER, etal. Chronic oxaliplatin resistance induces epithelial-to-mesenchymal transition in colorectal cancer cell lines. Clin Cancer Res. 2006;12(14 Pt 1):4147-4153.
    • (2006) Clin Cancer Res. , vol.12 , Issue.14 PART 1 , pp. 4147-4153
    • Yang, A.D.1    Fan, F.2    Camp, E.R.3
  • 8
    • 58049200145 scopus 로고    scopus 로고
    • Epithelial to mesenchymal transition derived from repeated exposure to gefitinib determines the sensitivity to EGFR inhibitors in A549, a non-small cell lung cancer cell line
    • Rho JK, Choi YJ, Lee JK, etal. Epithelial to mesenchymal transition derived from repeated exposure to gefitinib determines the sensitivity to EGFR inhibitors in A549, a non-small cell lung cancer cell line. Lung Cancer. 2009;63(2):219-226.
    • (2009) Lung Cancer. , vol.63 , Issue.2 , pp. 219-226
    • Rho, J.K.1    Choi, Y.J.2    Lee, J.K.3
  • 9
    • 24644487312 scopus 로고    scopus 로고
    • TGF-beta and epithelial-to-mesenchymal transitions
    • Zavadil J, Bottinger EP. TGF-beta and epithelial-to-mesenchymal transitions. Oncogene. 2005;24(37):5764-5774.
    • (2005) Oncogene. , vol.24 , Issue.37 , pp. 5764-5774
    • Zavadil, J.1    Bottinger, E.P.2
  • 10
    • 78650517027 scopus 로고    scopus 로고
    • The Cain and Abl of epithelial-mesenchymal transition and transforming growth factor-beta in mammary epithelial cells
    • Allington TM, Schiemann WP. The Cain and Abl of epithelial-mesenchymal transition and transforming growth factor-beta in mammary epithelial cells. Cells Tissues Organs. 2011;193(1-2):98-113.
    • (2011) Cells Tissues Organs. , vol.193 , Issue.1-2 , pp. 98-113
    • Allington, T.M.1    Schiemann, W.P.2
  • 11
    • 79952706985 scopus 로고    scopus 로고
    • Transforming growth factor-beta and the hallmarks of cancer
    • Tian M, Neil JR, Schiemann WP. Transforming growth factor-beta and the hallmarks of cancer. Cell Signal. 2011;23(6):951-962.
    • (2011) Cell Signal. , vol.23 , Issue.6 , pp. 951-962
    • Tian, M.1    Neil, J.R.2    Schiemann, W.P.3
  • 12
    • 78649987710 scopus 로고    scopus 로고
    • Transforming growth factor-beta-induced epithelial-mesenchymal transition facilitates epidermal growth factor-dependent breast cancer progression
    • Wendt MK, Smith JA, Schiemann WP. Transforming growth factor-beta-induced epithelial-mesenchymal transition facilitates epidermal growth factor-dependent breast cancer progression. Oncogene. 2010;29(49):6485-6498.
    • (2010) Oncogene. , vol.29 , Issue.49 , pp. 6485-6498
    • Wendt, M.K.1    Smith, J.A.2    Schiemann, W.P.3
  • 13
    • 77954862083 scopus 로고    scopus 로고
    • The pathophysiology of epithelial-mesenchymal transition induced by transforming growth factor-beta in normal and malignant mammary epithelial cells
    • Taylor MA, Parvani JG, Schiemann WP. The pathophysiology of epithelial-mesenchymal transition induced by transforming growth factor-beta in normal and malignant mammary epithelial cells. J Mammary Gland Biol Neoplasia. 2010;15(2):169-190.
    • (2010) J Mammary Gland Biol Neoplasia. , vol.15 , Issue.2 , pp. 169-190
    • Taylor, M.A.1    Parvani, J.G.2    Schiemann, W.P.3
  • 14
    • 72049091524 scopus 로고    scopus 로고
    • Targeting the transforming growth factor-beta signaling pathway in human cancer
    • Nagaraj NS, Datta PK. Targeting the transforming growth factor-beta signaling pathway in human cancer. Expert Opin Investig Drugs. 2010;19(1):77-91.
    • (2010) Expert Opin Investig Drugs. , vol.19 , Issue.1 , pp. 77-91
    • Nagaraj, N.S.1    Datta, P.K.2
  • 15
    • 53049097596 scopus 로고    scopus 로고
    • Hedgehog signaling, epithelial-to-mesenchymal transition and miRNA
    • Katoh Y, Katoh M. Hedgehog signaling, epithelial-to-mesenchymal transition and miRNA. Int J Mol Med. 2008;22(3):271-275.
    • (2008) Int J Mol Med. , vol.22 , Issue.3 , pp. 271-275
    • Katoh, Y.1    Katoh, M.2
  • 16
    • 67149143399 scopus 로고    scopus 로고
    • Inhibition of Hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer
    • Olive KP, Jacobetz MA, Davidson CJ, etal. Inhibition of Hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer. Science. 2009;324(5933):1457-1461.
    • (2009) Science. , vol.324 , Issue.5933 , pp. 1457-1461
    • Olive, K.P.1    Jacobetz, M.A.2    Davidson, C.J.3
  • 17
    • 79959736865 scopus 로고    scopus 로고
    • Epidermal growth factor receptor in pancreatic cancer
    • Oliveira-Cunha M, Newman WG, Siriwardena AK. Epidermal growth factor receptor in pancreatic cancer. Cancers. 2011;3(2):1513-1526.
    • (2011) Cancers. , vol.3 , Issue.2 , pp. 1513-1526
    • Oliveira-Cunha, M.1    Newman, W.G.2    Siriwardena, A.K.3
  • 18
    • 84863625227 scopus 로고    scopus 로고
    • Suppression of the epidermal growth factor receptor inhibits epithelial-mesenchymal transition in human pancreatic cancer PANC1 cells
    • Chang ZG, Wei JM, Qin CF, etal. Suppression of the epidermal growth factor receptor inhibits epithelial-mesenchymal transition in human pancreatic cancer PANC1 cells. Dig Dis Sci. 2012;57(5): 1181-1189.
    • (2012) Dig Dis Sci. , vol.57 , Issue.5 , pp. 1181-1189
    • Chang, Z.G.1    Wei, J.M.2    Qin, C.F.3
  • 19
    • 80055035200 scopus 로고    scopus 로고
    • DeltaNp63alpha-mediated induction of epidermal growth factor receptor promotes pancreatic cancer cell growth and chemoresistance
    • Danilov AV, Neupane D, Nagaraja AS, etal. DeltaNp63alpha-mediated induction of epidermal growth factor receptor promotes pancreatic cancer cell growth and chemoresistance. PLoS One. 2011;6(10): e26815.
    • (2011) PLoS One. , vol.6 , Issue.10
    • Danilov, A.V.1    Neupane, D.2    Nagaraja, A.S.3
  • 20
    • 84867306379 scopus 로고    scopus 로고
    • EGFR inhibition abrogates leiomyosarcoma cell chemoresistance through inactivation of survival pathways and impairment of CSC potential
    • Sette G, Salvati V, Memeo L, etal. EGFR inhibition abrogates leiomyosarcoma cell chemoresistance through inactivation of survival pathways and impairment of CSC potential. PLoS One. 2012;7(10):e46891.
    • (2012) PLoS One. , vol.7 , Issue.10
    • Sette, G.1    Salvati, V.2    Memeo, L.3
  • 21
    • 80655149151 scopus 로고    scopus 로고
    • Epithelial-mesenchymal-transition induced by EGFR activation interferes with cell migration and response to irradiation and cetuximab in head and neck cancer cells
    • Holz C, Niehr F, Boyko M, etal. Epithelial-mesenchymal-transition induced by EGFR activation interferes with cell migration and response to irradiation and cetuximab in head and neck cancer cells. Radiother Oncol. 2011;101(1):158-164.
    • (2011) Radiother Oncol. , vol.101 , Issue.1 , pp. 158-164
    • Holz, C.1    Niehr, F.2    Boyko, M.3
  • 22
    • 77955715149 scopus 로고    scopus 로고
    • Treatment of pancreatic cancer with epidermal growth factor receptor-targeted therapy
    • Faller BA, Burtness B. Treatment of pancreatic cancer with epidermal growth factor receptor-targeted therapy. Biologics. 2009;3:419-428.
    • (2009) Biologics. , vol.3 , pp. 419-428
    • Faller, B.A.1    Burtness, B.2
  • 23
    • 84884379324 scopus 로고    scopus 로고
    • A novel epidermal growth factor receptor-signaling platform and its targeted translation in pancreatic cancer
    • Gilmour AM, Abdulkhalek S, Cheng TSW, etal. A novel epidermal growth factor receptor-signaling platform and its targeted translation in pancreatic cancer. Cell Signal. 2013;25(12):2587-2603.
    • (2013) Cell Signal. , vol.25 , Issue.12 , pp. 2587-2603
    • Gilmour, A.M.1    Abdulkhalek, S.2    Cheng, T.S.W.3
  • 24
    • 77953028002 scopus 로고    scopus 로고
    • Neu1 sialidase and matrix metalloproteinase-9 cross-talk is essential for neurotrophin activation of Trk receptors and cellular signaling
    • Jayanth P, Amith SR, Gee K, Szewczuk MR. Neu1 sialidase and matrix metalloproteinase-9 cross-talk is essential for neurotrophin activation of Trk receptors and cellular signaling. Cell Signal. 2010;22(8): 1193-1205.
    • (2010) Cell Signal. , vol.22 , Issue.8 , pp. 1193-1205
    • Jayanth, P.1    Amith, S.R.2    Gee, K.3    Szewczuk, M.R.4
  • 25
    • 80054686618 scopus 로고    scopus 로고
    • Neu1 sialidase and matrix metalloproteinase-9 cross-talk is essential for Toll-like receptor activation and cellular signaling
    • Abdulkhalek S, Amith SR, Franchuk SL, etal. Neu1 sialidase and matrix metalloproteinase-9 cross-talk is essential for Toll-like receptor activation and cellular signaling. J Biol Chem. 2011;286(42):36532-36549.
    • (2011) J Biol Chem. , vol.286 , Issue.42 , pp. 36532-36549
    • Abdulkhalek, S.1    Amith, S.R.2    Franchuk, S.L.3
  • 26
    • 84865325434 scopus 로고    scopus 로고
    • G-protein coupled receptor agonists mediate Neu1 sialidase and matrix metalloproteinase-9 cross-talk to induce transactivation of TOLL-like receptors and cellular signaling
    • Abdulkhalek S, Guo M, Amith SR, Jayanth P, Szewczuk MR. G-protein coupled receptor agonists mediate Neu1 sialidase and matrix metalloproteinase-9 cross-talk to induce transactivation of TOLL-like receptors and cellular signaling. Cell Signal. 2012;24(11):2035-2042.
    • (2012) Cell Signal. , vol.24 , Issue.11 , pp. 2035-2042
    • Abdulkhalek, S.1    Guo, M.2    Amith, S.R.3    Jayanth, P.4    Szewczuk, M.R.5
  • 27
    • 80355133835 scopus 로고    scopus 로고
    • Detection of Neu1 sialidase activity in regulating Toll-like receptor activation
    • Amith SR, Jayanth P, Finlay T, etal. Detection of Neu1 sialidase activity in regulating Toll-like receptor activation. J Vis Exp. 2010(43).
    • (2010) J Vis Exp. , Issue.43
    • Amith, S.R.1    Jayanth, P.2    Finlay, T.3
  • 28
    • 70450223518 scopus 로고    scopus 로고
    • Neu1 desialylation of sialyl alpha-2,3-linked beta-galactosyl residues of Toll-like receptor 4 is essential for receptor activation and cellular signaling
    • Amith SR, Jayanth P, Franchuk S, etal. Neu1 desialylation of sialyl alpha-2,3-linked beta-galactosyl residues of Toll-like receptor 4 is essential for receptor activation and cellular signaling. Cell Signal. 2010;22(2):314-324.
    • (2010) Cell Signal. , vol.22 , Issue.2 , pp. 314-324
    • Amith, S.R.1    Jayanth, P.2    Franchuk, S.3
  • 29
    • 77649257934 scopus 로고    scopus 로고
    • Dependence of pathogen molecule-induced toll-like receptor activation and cell function on Neu1 sialidase
    • Amith SR, Jayanth P, Franchuk S, etal. Dependence of pathogen molecule-induced toll-like receptor activation and cell function on Neu1 sialidase. Glycoconjug J. 2009;26(9):1197-1212.
    • (2009) Glycoconjug J. , vol.26 , Issue.9 , pp. 1197-1212
    • Amith, S.R.1    Jayanth, P.2    Franchuk, S.3
  • 30
    • 84880440988 scopus 로고    scopus 로고
    • Neu1 sialidase and matrix metalloproteinase-9 cross-talk regulates nucleic acid-induced endosomal TOLL-like receptor-7 and-9 activation, cellular signaling and pro-inflammatory responses
    • Abdulkhalek S, Szewczuk MR. Neu1 sialidase and matrix metalloproteinase-9 cross-talk regulates nucleic acid-induced endosomal TOLL-like receptor-7 and-9 activation, cellular signaling and pro-inflammatory responses. Cell Signal. 2013;25(11):2093-2105.
    • (2013) Cell Signal. , vol.25 , Issue.11 , pp. 2093-2105
    • Abdulkhalek, S.1    Szewczuk, M.R.2
  • 31
    • 84880426665 scopus 로고    scopus 로고
    • A novel G-protein-coupled receptor-signaling platform and its targeted translation in human disease
    • Abdulkhalek S, Hrynyk M, Szewczuk MR. A novel G-protein-coupled receptor-signaling platform and its targeted translation in human disease. Research and Reports in Biochemistry. 2013;3:17-30.
    • (2013) Research and Reports in Biochemistry. , vol.3 , pp. 17-30
    • Abdulkhalek, S.1    Hrynyk, M.2    Szewczuk, M.R.3
  • 32
    • 54049124684 scopus 로고    scopus 로고
    • Limited inhibitory effects of oseltamivir and zanamivir on human sialidases
    • Hata K, Koseki K, Yamaguchi K, etal. Limited inhibitory effects of oseltamivir and zanamivir on human sialidases. Antimicrob Agents Chemother. 2008;52(10):3484-3491.
    • (2008) Antimicrob Agents Chemother. , vol.52 , Issue.10 , pp. 3484-3491
    • Hata, K.1    Koseki, K.2    Yamaguchi, K.3
  • 33
    • 33845881168 scopus 로고    scopus 로고
    • Sialidase expression in activated human T lymphocytes influences production of IFN-gamma
    • Nan X, Carubelli I, Stamatos NM. Sialidase expression in activated human T lymphocytes influences production of IFN-gamma. J Leukoc Biol. 2007;81(1):284-296.
    • (2007) J Leukoc Biol. , vol.81 , Issue.1 , pp. 284-296
    • Nan, X.1    Carubelli, I.2    Stamatos, N.M.3
  • 34
    • 0034697387 scopus 로고    scopus 로고
    • Superoxide produced by activated neutrophils efficiently reduces the tetrazolium salt, WST-1 to produce a soluble formazan: A simple colorimetric assay for measuring respiratory burst activation and for screening anti-inflammatory agents
    • Tan AS, Berridge MV. Superoxide produced by activated neutrophils efficiently reduces the tetrazolium salt, WST-1 to produce a soluble formazan: a simple colorimetric assay for measuring respiratory burst activation and for screening anti-inflammatory agents. J Immunol Methods. 2000;238(1-2):59-68.
    • (2000) J Immunol Methods. , vol.238 , Issue.1-2 , pp. 59-68
    • Tan, A.S.1    Berridge, M.V.2
  • 35
    • 79952453864 scopus 로고    scopus 로고
    • Pancreatic cancer cells resistant to chemoradiotherapy rich in "stem-cell-like" tumor cells
    • Du Z, Qin R, Wei C, etal. Pancreatic cancer cells resistant to chemoradiotherapy rich in "stem-cell-like" tumor cells. Dig Dis Sci. 2011;56(3):741-750.
    • (2011) Dig Dis Sci. , vol.56 , Issue.3 , pp. 741-750
    • Du, Z.1    Qin, R.2    Wei, C.3
  • 36
    • 38549128935 scopus 로고    scopus 로고
    • VE-cadherin: The major endothelial adhesion molecule controlling cellular junctions and blood vessel formation
    • Vestweber D. VE-cadherin: the major endothelial adhesion molecule controlling cellular junctions and blood vessel formation. Arterioscler Thromb Vasc Biol. 2008;28(2):223-232.
    • (2008) Arterioscler Thromb Vasc Biol. , vol.28 , Issue.2 , pp. 223-232
    • Vestweber, D.1
  • 37
    • 70349165716 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition in cancer metastasis: Mechanisms, markers and strategies to overcome drug resistance in the clinic
    • Voulgari A, Pintzas A. Epithelial-mesenchymal transition in cancer metastasis: mechanisms, markers and strategies to overcome drug resistance in the clinic. Biochim Biophys Acta. 2009;1796(2): 75-90.
    • (2009) Biochim Biophys Acta. , vol.1796 , Issue.2 , pp. 75-90
    • Voulgari, A.1    Pintzas, A.2
  • 38
    • 70450198396 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transitions in development and disease
    • Thiery JP, Acloque H, Huang RY, Nieto MA. Epithelial-mesenchymal transitions in development and disease. Cell. 2009;139(5):871-890.
    • (2009) Cell. , vol.139 , Issue.5 , pp. 871-890
    • Thiery, J.P.1    Acloque, H.2    Huang, R.Y.3    Nieto, M.A.4
  • 39
    • 0034934078 scopus 로고    scopus 로고
    • Expression and functional significance of VE-cadherin in aggressive human melanoma cells: Role in vasculogenic mimicry
    • Hendrix MJ, Seftor EA, Meltzer PS, etal. Expression and functional significance of VE-cadherin in aggressive human melanoma cells: role in vasculogenic mimicry. Proc Natl Acad Sci U S A. 2001;98(14): 8018-8023.
    • (2001) Proc Natl Acad Sci U S A. , vol.98 , Issue.14 , pp. 8018-8023
    • Hendrix, M.J.1    Seftor, E.A.2    Meltzer, P.S.3
  • 40
    • 84863272837 scopus 로고    scopus 로고
    • Neu1 sialidase expressed in human airway epithelia regulates epidermal growth factor receptor (EGFR) and MUC1 protein signaling
    • Lillehoj EP, Hyun SW, Feng C, etal. Neu1 sialidase expressed in human airway epithelia regulates epidermal growth factor receptor (EGFR) and MUC1 protein signaling. J Biol Chem. 2012;287(11): 8214-8231.
    • (2012) J Biol Chem. , vol.287 , Issue.11 , pp. 8214-8231
    • Lillehoj, E.P.1    Hyun, S.W.2    Feng, C.3
  • 41
    • 84879824031 scopus 로고    scopus 로고
    • MUC1 induces drug resistance in pancreatic cancer cells via upregulation of multidrug resistance genes
    • Nath S, Daneshvar K, Roy LD, etal. MUC1 induces drug resistance in pancreatic cancer cells via upregulation of multidrug resistance genes. Oncogenesis. 2013;2:e51.
    • (2013) Oncogenesis. , vol.2
    • Nath, S.1    Daneshvar, K.2    Roy, L.D.3
  • 42
    • 62049084618 scopus 로고    scopus 로고
    • Contribution of sialidase NEU1 to suppression of metastasis of human colon cancer cells through desialylation of integrin beta4
    • Uemura T, Shiozaki K, Yamaguchi K, etal. Contribution of sialidase NEU1 to suppression of metastasis of human colon cancer cells through desialylation of integrin beta4. Oncogene. 2009;28(9):1218-1229.
    • (2009) Oncogene. , vol.28 , Issue.9 , pp. 1218-1229
    • Uemura, T.1    Shiozaki, K.2    Yamaguchi, K.3
  • 43
    • 0034630507 scopus 로고    scopus 로고
    • Modulation of EGF receptor activity by changes in the GM3 content in a human epidermoid carcinoma cell line, A431
    • Meuillet EJ, Mania-Farnell B, George D, Inokuchi JI, Bremer EG. Modulation of EGF receptor activity by changes in the GM3 content in a human epidermoid carcinoma cell line, A431. Exp Cell Res. 2000;256(1):74-82.
    • (2000) Exp Cell Res. , vol.256 , Issue.1 , pp. 74-82
    • Meuillet, E.J.1    Mania-Farnell, B.2    George, D.3    Inokuchi, J.I.4    Bremer, E.G.5
  • 44
    • 0035871076 scopus 로고    scopus 로고
    • Modulation of epidermal growth factor receptor phosphorylation by endogenously expressed gangliosides
    • Zurita AR, Maccioni HJ, Daniotti JL. Modulation of epidermal growth factor receptor phosphorylation by endogenously expressed gangliosides. Biochem J. 2001;355(Pt 2):465-472.
    • (2001) Biochem J. , vol.355 , Issue.PART 2 , pp. 465-472
    • Zurita, A.R.1    McCioni, H.J.2    Daniotti, J.L.3
  • 45
    • 0037155799 scopus 로고    scopus 로고
    • Interaction of the extracellular domain of the epidermal growth factor receptor with gangliosides
    • Miljan EA, Meuillet EJ, Mania-Farnell B, etal. Interaction of the extracellular domain of the epidermal growth factor receptor with gangliosides. J Biol Chem. 2002;277(12):10108-10113.
    • (2002) J Biol Chem. , vol.277 , Issue.12 , pp. 10108-10113
    • Miljan, E.A.1    Meuillet, E.J.2    Mania-Farnell, B.3
  • 46
    • 0036277843 scopus 로고    scopus 로고
    • Inhibition of human neuroblastoma cell proliferation and EGF receptor phosphorylation by gangliosides GM1, GM3, GD1A and GT1B
    • Mirkin BL, Clark SH, Zhang C. Inhibition of human neuroblastoma cell proliferation and EGF receptor phosphorylation by gangliosides GM1, GM3, GD1A and GT1B. Cell Prolif. 2002;35(2):105-115.
    • (2002) Cell Prolif. , vol.35 , Issue.2 , pp. 105-115
    • Mirkin, B.L.1    Clark, S.H.2    Zhang, C.3
  • 47
    • 1542676831 scopus 로고    scopus 로고
    • Ganglioside GM3 blocks the activation of epidermal growth factor receptor induced by integrin at specific tyrosine sites
    • Wang XQ, Sun P, Paller AS. Ganglioside GM3 blocks the activation of epidermal growth factor receptor induced by integrin at specific tyrosine sites. J Biol Chem. 2003;278(49):48770-48778.
    • (2003) J Biol Chem. , vol.278 , Issue.49 , pp. 48770-48778
    • Wang, X.Q.1    Sun, P.2    Paller, A.S.3
  • 48
    • 80755163563 scopus 로고    scopus 로고
    • Regulation of epidermal growth factor receptor through interaction of ganglioside GM3 with GlcNAc of N-linked glycan of the receptor: Demonstration in ldlD cells
    • Guan F, Handa K, Hakomori SI. Regulation of epidermal growth factor receptor through interaction of ganglioside GM3 with GlcNAc of N-linked glycan of the receptor: demonstration in ldlD cells. Neurochem Res. 2011;36(9):1645-1653.
    • (2011) Neurochem Res. , vol.36 , Issue.9 , pp. 1645-1653
    • Guan, F.1    Handa, K.2    Hakomori, S.I.3
  • 49
    • 84877711924 scopus 로고    scopus 로고
    • Ganglioside GM3 inhibits murine ascites hepatoma cell motility and migration in vitro through inhibition of phosphorylation of EGFR at specific tyrosine sites and PI3K/AKT signaling pathway
    • Huang X, Li Y, Zhang J, Xu Y, Tian Y, Ma K. Ganglioside GM3 inhibits murine ascites hepatoma cell motility and migration in vitro through inhibition of phosphorylation of EGFR at specific tyrosine sites and PI3K/AKT signaling pathway. J Cell Biochem. 2013;114(7): 1616-1624.
    • (2013) J Cell Biochem. , vol.114 , Issue.7 , pp. 1616-1624
    • Huang, X.1    Li, Y.2    Zhang, J.3    Xu, Y.4    Tian, Y.5    Ma, K.6
  • 50
    • 0032922085 scopus 로고    scopus 로고
    • Sialidase gene transfection enhances epidermal growth factor receptor activity in an epidermoid carcinoma cell line, A431
    • Meuillet EJ, Kroes R, Yamamoto H, etal. Sialidase gene transfection enhances epidermal growth factor receptor activity in an epidermoid carcinoma cell line, A431. Cancer Res. 1999;59(1):234-240.
    • (1999) Cancer Res. , vol.59 , Issue.1 , pp. 234-240
    • Meuillet, E.J.1    Kroes, R.2    Yamamoto, H.3
  • 51
    • 35148825636 scopus 로고    scopus 로고
    • Chemoresistance to paclitaxel induces epithelial-mesenchymal transition and enhances metastatic potential for epithelial ovarian carcinoma cells
    • Kajiyama H, Shibata K, Terauchi M, etal. Chemoresistance to paclitaxel induces epithelial-mesenchymal transition and enhances metastatic potential for epithelial ovarian carcinoma cells. Int J Oncol. 2007;31(2): 277-283.
    • (2007) Int J Oncol. , vol.31 , Issue.2 , pp. 277-283
    • Kajiyama, H.1    Shibata, K.2    Terauchi, M.3
  • 52
    • 69249111313 scopus 로고    scopus 로고
    • Reversibility of epithelial-mesenchymal transition (EMT) induced in breast cancer cells by activation of urokinase receptor-dependent cell signaling
    • Jo M, Lester RD, Montel V, Eastman B, Takimoto S, Gonias SL. Reversibility of epithelial-mesenchymal transition (EMT) induced in breast cancer cells by activation of urokinase receptor-dependent cell signaling. J Biol Chem. 2009;284(34):22825-22833.
    • (2009) J Biol Chem. , vol.284 , Issue.34 , pp. 22825-22833
    • Jo, M.1    Lester, R.D.2    Montel, V.3    Eastman, B.4    Takimoto, S.5    Gonias, S.L.6
  • 53
    • 84870425389 scopus 로고    scopus 로고
    • Interplay between neural-cadherin and vascular endothelial-cadherin in breast cancer progression
    • Rezaei M, Friedrich K, Wielockx B, etal. Interplay between neural-cadherin and vascular endothelial-cadherin in breast cancer progression. Breast Cancer Res. 2012;14(6):R154.
    • (2012) Breast Cancer Res. , vol.14 , Issue.6
    • Rezaei, M.1    Friedrich, K.2    Wielockx, B.3
  • 54
    • 40449093134 scopus 로고    scopus 로고
    • Vascular endothelial cadherin promotes breast cancer progression via transforming growth factor beta signaling
    • Labelle M, Schnittler HJ, Aust DE, etal. Vascular endothelial cadherin promotes breast cancer progression via transforming growth factor beta signaling. Cancer Res. 2008;68(5):1388-1397.
    • (2008) Cancer Res. , vol.68 , Issue.5 , pp. 1388-1397
    • Labelle, M.1    Schnittler, H.J.2    Aust, D.E.3
  • 55
    • 84872185689 scopus 로고    scopus 로고
    • N-cadherin expression is a potential survival mechanism of gefitinib-resistant lung cancer cells
    • Yamauchi M, Yoshino I, Yamaguchi R, etal. N-cadherin expression is a potential survival mechanism of gefitinib-resistant lung cancer cells. Am J Cancer Res. 2011;1(7):823-833.
    • (2011) Am J Cancer Res. , vol.1 , Issue.7 , pp. 823-833
    • Yamauchi, M.1    Yoshino, I.2    Yamaguchi, R.3
  • 56
    • 79954596010 scopus 로고    scopus 로고
    • Slug confers resistance to the epidermal growth factor receptor tyrosine kinase inhibitor
    • Chang TH, Tsai MF, Su KY, etal. Slug confers resistance to the epidermal growth factor receptor tyrosine kinase inhibitor. Am J Respir Crit Care Med. 2011;183(8):1071-1079.
    • (2011) Am J Respir Crit Care Med. , vol.183 , Issue.8 , pp. 1071-1079
    • Chang, T.H.1    Tsai, M.F.2    Su, K.Y.3
  • 57
    • 84867578091 scopus 로고    scopus 로고
    • EMT-activating transcription factors in cancer: Beyond EMT and tumor invasiveness
    • Sanchez-Tillo E, Liu Y, de Barrios O, etal. EMT-activating transcription factors in cancer: beyond EMT and tumor invasiveness. Cell Mol Life Sci. 2012;69(20):3429-3456.
    • (2012) Cell Mol Life Sci. , vol.69 , Issue.20 , pp. 3429-3456
    • Sanchez-Tillo, E.1    Liu, Y.2    de Barrios, O.3
  • 58
    • 0038756636 scopus 로고    scopus 로고
    • Transforming growth factor beta-1 induces snail transcription factor in epithelial cell lines: Mechanisms for epithelial mesenchymal transitions
    • Peinado H, Quintanilla M, Cano A. Transforming growth factor beta-1 induces snail transcription factor in epithelial cell lines: mechanisms for epithelial mesenchymal transitions. J Biol Chem. 2003;278(23):21113-21123.
    • (2003) J Biol Chem. , vol.278 , Issue.23 , pp. 21113-21123
    • Peinado, H.1    Quintanilla, M.2    Cano, A.3
  • 59
    • 0037326569 scopus 로고    scopus 로고
    • The transcription factor Slug represses E-cadherin expression and induces epithelial to mesenchymal transitions: A comparison with Snail and E47 repressors
    • Bolos V, Peinado H, Perez-Moreno MA, Fraga MF, Esteller M, Cano A. The transcription factor Slug represses E-cadherin expression and induces epithelial to mesenchymal transitions: a comparison with Snail and E47 repressors. J Cell Sci. 2003;116(Pt 3):499-511.
    • (2003) J Cell Sci. , vol.116 , Issue.PART 3 , pp. 499-511
    • Bolos, V.1    Peinado, H.2    Perez-Moreno, M.A.3    Fraga, M.F.4    Esteller, M.5    Cano, A.6
  • 60
    • 58149316623 scopus 로고    scopus 로고
    • Snail and Slug promote epithelial-mesenchymal transition through beta-catenin-T-cell factor-4-dependent expression of transforming growth factor-beta3
    • Medici D, Hay ED, Olsen BR. Snail and Slug promote epithelial-mesenchymal transition through beta-catenin-T-cell factor-4-dependent expression of transforming growth factor-beta3. Mol Biol Cell. 2008;19(11):4875-4887.
    • (2008) Mol Biol Cell. , vol.19 , Issue.11 , pp. 4875-4887
    • Medici, D.1    Hay, E.D.2    Olsen, B.R.3
  • 61
    • 0036233040 scopus 로고    scopus 로고
    • Role of basic fibroblast growth factor-2 in epithelial-mesenchymal transformation
    • Strutz F, Zeisberg M, Ziyadeh FN, etal. Role of basic fibroblast growth factor-2 in epithelial-mesenchymal transformation. Kidney Int. 2002;61(5):1714-1728.
    • (2002) Kidney Int. , vol.61 , Issue.5 , pp. 1714-1728
    • Strutz, F.1    Zeisberg, M.2    Ziyadeh, F.N.3
  • 62
    • 0037513432 scopus 로고    scopus 로고
    • Role of TGF-beta signaling in extracellular matrix production under high glucose conditions
    • Li JH, Huang XR, Zhu HJ, Johnson R, Lan HY. Role of TGF-beta signaling in extracellular matrix production under high glucose conditions. Kidney Int. 2003;63(6):2010-2019.
    • (2003) Kidney Int. , vol.63 , Issue.6 , pp. 2010-2019
    • Li, J.H.1    Huang, X.R.2    Zhu, H.J.3    Johnson, R.4    Lan, H.Y.5
  • 63
    • 0034799176 scopus 로고    scopus 로고
    • Renal fibrosis: Collagen composition and assembly regulates epithelial-mesenchymal transdifferentiation
    • Zeisberg M, Bonner G, Maeshima Y, etal. Renal fibrosis: collagen composition and assembly regulates epithelial-mesenchymal transdifferentiation. Am J Pathol. 2001;159(4):1313-1321.
    • (2001) Am J Pathol. , vol.159 , Issue.4 , pp. 1313-1321
    • Zeisberg, M.1    Bonner, G.2    Maeshima, Y.3
  • 64
    • 85047698213 scopus 로고    scopus 로고
    • Correlation of Snail expression with histological grade and lymph node status in breast carcinomas
    • Blanco MJ, Moreno-Bueno G, Sarrio D, etal. Correlation of Snail expression with histological grade and lymph node status in breast carcinomas. Oncogene. 2002;21(20):3241-3246.
    • (2002) Oncogene. , vol.21 , Issue.20 , pp. 3241-3246
    • Blanco, M.J.1    Moreno-Bueno, G.2    Sarrio, D.3
  • 65
    • 24344483881 scopus 로고    scopus 로고
    • Upregulation of MMP-9 in MDCK epithelial cell line in response to expression of the Snail transcription factor
    • Jorda M, Olmeda D, Vinyals A, etal. Upregulation of MMP-9 in MDCK epithelial cell line in response to expression of the Snail transcription factor. J Cell Sci. 2005;118(Pt 15):3371-3385.
    • (2005) J Cell Sci. , vol.118 , Issue.PART 15 , pp. 3371-3385
    • Jorda, M.1    Olmeda, D.2    Vinyals, A.3
  • 66
    • 65549154497 scopus 로고    scopus 로고
    • Critical role of Smad2 in tumor suppression and transforming growth factor-beta-induced apoptosis of prostate epithelial cells
    • Yang J, Wahdan-Alaswad R, Danielpour D. Critical role of Smad2 in tumor suppression and transforming growth factor-beta-induced apoptosis of prostate epithelial cells. Cancer Res. 2009;69(6): 2185-2190.
    • (2009) Cancer Res. , vol.69 , Issue.6 , pp. 2185-2190
    • Yang, J.1    Wahdan-Alaswad, R.2    Danielpour, D.3
  • 67
    • 0347626102 scopus 로고    scopus 로고
    • Reduction in Smad2/3 signaling enhances tumorigenesis but suppresses metastasis of breast cancer cell lines
    • Tian F, DaCosta Byfield S, Parks WT, etal. Reduction in Smad2/3 signaling enhances tumorigenesis but suppresses metastasis of breast cancer cell lines. Cancer Res. 2003;63(23):8284-8292.
    • (2003) Cancer Res. , vol.63 , Issue.23 , pp. 8284-8292
    • Tian, F.1    DaCosta Byfield, S.2    Parks, W.T.3
  • 68
    • 48749122568 scopus 로고    scopus 로고
    • Keratinocyte-specific Smad2 ablation results in increased epithelial-mesenchymal transition during skin cancer formation and progression
    • Hoot KE, Lighthall J, Han G, etal. Keratinocyte-specific Smad2 ablation results in increased epithelial-mesenchymal transition during skin cancer formation and progression. J Clin Invest. 2008;118(8): 2722-2732.
    • (2008) J Clin Invest. , vol.118 , Issue.8 , pp. 2722-2732
    • Hoot, K.E.1    Lighthall, J.2    Han, G.3
  • 69
    • 77957855880 scopus 로고    scopus 로고
    • HGF upregulation contributes to angiogenesis in mice with keratinocyte-specific Smad2 deletion
    • Hoot KE, Oka M, Han G, Bottinger E, Zhang Q, Wang XJ. HGF upregulation contributes to angiogenesis in mice with keratinocyte-specific Smad2 deletion. J Clin Invest. 2010;120(10): 3606-3616.
    • (2010) J Clin Invest. , vol.120 , Issue.10 , pp. 3606-3616
    • Hoot, K.E.1    Oka, M.2    Han, G.3    Bottinger, E.4    Zhang, Q.5    Wang, X.J.6
  • 70
    • 84856772032 scopus 로고    scopus 로고
    • Key signaling nodes in mammary gland development and cancer: Smad signal integration in epithelial cell plasticity
    • Sundqvist A, Ten Dijke P, van Dam H. Key signaling nodes in mammary gland development and cancer: Smad signal integration in epithelial cell plasticity. Breast Cancer Res. 2012;14(1):204.
    • (2012) Breast Cancer Res. , vol.14 , Issue.1 , pp. 204
    • Sundqvist, A.1    Ten Dijke, P.2    van Dam, H.3
  • 71
    • 0037621860 scopus 로고    scopus 로고
    • Regulation of TGF-beta signaling and its roles in progression of tumors
    • Miyazono K, Suzuki H, Imamura T. Regulation of TGF-beta signaling and its roles in progression of tumors. Cancer Sci. 2003;94(3): 230-234.
    • (2003) Cancer Sci. , vol.94 , Issue.3 , pp. 230-234
    • Miyazono, K.1    Suzuki, H.2    Imamura, T.3
  • 72
    • 84881236485 scopus 로고    scopus 로고
    • Specific interactions between Smad proteins and AP-1 components determine TGFbeta-induced breast cancer cell invasion
    • Sundqvist A, Zieba A, Vasilaki E, etal. Specific interactions between Smad proteins and AP-1 components determine TGFbeta-induced breast cancer cell invasion. Oncogene. 2013;32(31):3606-3615.
    • (2013) Oncogene. , vol.32 , Issue.31 , pp. 3606-3615
    • Sundqvist, A.1    Zieba, A.2    Vasilaki, E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.