-
1
-
-
20544440861
-
Aging muscle
-
Nair KS. 2005. Aging muscle. Am. J. Clin. Nutr. 81:953-963.
-
(2005)
Am. J. Clin. Nutr.
, vol.81
, pp. 953-963
-
-
Nair, K.S.1
-
2
-
-
84875902181
-
Organ-specific mediation of lifespan extension: more than a gut feeling?
-
Rera M, Azizi MJ, Walker DW. 2013. Organ-specific mediation of lifespan extension: more than a gut feeling? Ageing Res. Rev. 12:436-444. http://dx.doi.org/10.1016/j.arr.2012.05.003.
-
(2013)
Ageing Res. Rev.
, vol.12
, pp. 436-444
-
-
Rera, M.1
Azizi, M.J.2
Walker, D.W.3
-
3
-
-
78650918920
-
FOXO/4E-BP signaling in Drosophila muscles regulates organism-wide proteostasis during aging
-
Demontis F, Perrimon N. 2010. FOXO/4E-BP signaling in Drosophila muscles regulates organism-wide proteostasis during aging. Cell 143:813-825. http://dx.doi.org/10.1016/j.cell.2010.10.007.
-
(2010)
Cell
, vol.143
, pp. 813-825
-
-
Demontis, F.1
Perrimon, N.2
-
4
-
-
39349083915
-
Adapting proteostasis for disease intervention
-
Balch WE, Morimoto RI, Dillin A, Kelly JW. 2008. Adapting proteostasis for disease intervention. Science 319:916-919. http://dx.doi.org/10.1126/science.1141448.
-
(2008)
Science
, vol.319
, pp. 916-919
-
-
Balch, W.E.1
Morimoto, R.I.2
Dillin, A.3
Kelly, J.W.4
-
5
-
-
77955647254
-
Towards the treatment of polyglutamine diseases: the modulatory role of protein context
-
Robertson AL, Bottomley SP. 2010. Towards the treatment of polyglutamine diseases: the modulatory role of protein context. Curr. Med. Chem. 17:3058-3068. http://dx.doi.org/10.2174/092986710791959800.
-
(2010)
Curr. Med. Chem.
, vol.17
, pp. 3058-3068
-
-
Robertson, A.L.1
Bottomley, S.P.2
-
6
-
-
56749104288
-
Inclusion-body myositis: muscle-fiber molecular pathology and possible pathogenic significance of its similarity to Alzheimer's and Parkinson's disease brains
-
Askanas V, Engel WK. 2008. Inclusion-body myositis: muscle-fiber molecular pathology and possible pathogenic significance of its similarity to Alzheimer's and Parkinson's disease brains. Acta Neuropathol. 116:583-595. http://dx.doi.org/10.1007/s00401-008-0449-0.
-
(2008)
Acta Neuropathol
, vol.116
, pp. 583-595
-
-
Askanas, V.1
Engel, W.K.2
-
7
-
-
84872320106
-
Protein aggregate myopathies: the many faces of an expanding disease group
-
Schröder R. 2013. Protein aggregate myopathies: the many faces of an expanding disease group. Acta Neuropathol. 125:1-2. http://dx.doi.org /10.1007/s00401-012-1071-8.
-
(2013)
Acta Neuropathol
, vol.125
, pp. 1-2
-
-
Schröder, R.1
-
8
-
-
66949145779
-
Inclusion body myositis: a degenerative muscle disease associated with intra-muscle fiber multiprotein aggregates, proteasome inhibition, endoplasmic reticulum stress and decreased lysosomal degradation
-
Askanas V, Engel WK, Nogalska A. 2009. Inclusion body myositis: a degenerative muscle disease associated with intra-muscle fiber multiprotein aggregates, proteasome inhibition, endoplasmic reticulum stress and decreased lysosomal degradation. Brain Pathol. 19:493-506. http://dx.doi.org/10.1111/j.1750-3639.2009.00290.x.
-
(2009)
Brain Pathol
, vol.19
, pp. 493-506
-
-
Askanas, V.1
Engel, W.K.2
Nogalska, A.3
-
10
-
-
46549084254
-
Protein misfolding and disease: from the test tube to the organism
-
Luheshi LM, Crowther DC, Dobson CM. 2008. Protein misfolding and disease: from the test tube to the organism. Curr. Opin. Chem. Biol. 12: 25-31. http://dx.doi.org/10.1016/j.cbpa.2008.02.011.
-
(2008)
Curr. Opin. Chem. Biol.
, vol.12
, pp. 25-31
-
-
Luheshi, L.M.1
Crowther, D.C.2
Dobson, C.M.3
-
11
-
-
79954628218
-
Drosophila as a model for age-related impairment in locomotor and other behaviors
-
Jones MA, Grotewiel M. 2011. Drosophila as a model for age-related impairment in locomotor and other behaviors. Exp. Gerontol. 46:320-325. http://dx.doi.org/10.1016/j.exger.2010.08.012.
-
(2011)
Exp. Gerontol.
, vol.46
, pp. 320-325
-
-
Jones, M.A.1
Grotewiel, M.2
-
12
-
-
79954995198
-
Expression of human amyloid precursor protein in the skeletal muscles of Drosophila results in age- and activity-dependent muscle weakness
-
Kim C, Srivastava S, Rice M, Godenschwege TA, Bentley B, Ravi S, Shao S, Woodard CT, Schwartz LM. 2011. Expression of human amyloid precursor protein in the skeletal muscles of Drosophila results in age- and activity-dependent muscle weakness. BMC Physiol. 11:7. http://dx.doi.org/10.1186/1472-6793-11-7.
-
(2011)
BMC Physiol
, vol.11
, pp. 7
-
-
Kim, C.1
Srivastava, S.2
Rice, M.3
Godenschwege, T.A.4
Bentley, B.5
Ravi, S.6
Shao, S.7
Woodard, C.T.8
Schwartz, L.M.9
-
13
-
-
33646768641
-
A Drosophila model of oculopharyngeal muscular dystrophy reveals intrinsic toxicity of PABPN1
-
Chartier A, Benoit B, Simonelig M. 2006. A Drosophila model of oculopharyngeal muscular dystrophy reveals intrinsic toxicity of PABPN1. EMBO J. 25:2253-2262. http://dx.doi.org/10.1038/sj.emboj.7601117.
-
(2006)
EMBO J
, vol.25
, pp. 2253-2262
-
-
Chartier, A.1
Benoit, B.2
Simonelig, M.3
-
14
-
-
84861702034
-
Expression of the inclusion body myopathy 3 mutation in Drosophila depresses myosin function and stability and recapitulates muscle inclusions and weakness
-
Wang Y, Melkani GC, Suggs JA, Melkani A, Kronert WA, Cammarato A, Bernstein SI. 2012. Expression of the inclusion body myopathy 3 mutation in Drosophila depresses myosin function and stability and recapitulates muscle inclusions and weakness. Mol. Biol. Cell 23:2057-2065. http://dx.doi.org/10.1091/mbc.E12-02-0120.
-
(2012)
Mol. Biol. Cell
, vol.23
, pp. 2057-2065
-
-
Wang, Y.1
Melkani, G.C.2
Suggs, J.A.3
Melkani, A.4
Kronert, W.A.5
Cammarato, A.6
Bernstein, S.I.7
-
15
-
-
30444440735
-
Regulation of skeletal muscle gene expression by p38 MAP kinases
-
Lluís F, Perdiguero E, Nebreda AR, Muñoz-Cánoves P. 2006. Regulation of skeletal muscle gene expression by p38 MAP kinases. Trends Cell Biol. 16:36-44. http://dx.doi.org/10.1016/j.tcb.2005.11.002.
-
(2006)
Trends Cell Biol
, vol.16
, pp. 36-44
-
-
Lluís, F.1
Perdiguero, E.2
Nebreda, A.R.3
Muñoz-Cánoves, P.4
-
16
-
-
34547687918
-
Genetic deficiency of p38 reveals its critical role in myoblast cell cycle exit: the p38-JNK connection
-
Perdiguero E, Ruiz-Bonilla V, Serrano AL, Muñoz-Cánoves P. 2007. Genetic deficiency of p38 reveals its critical role in myoblast cell cycle exit: the p38-JNK connection. Cell Cycle 6:1298-1303. http://dx.doi.org /10.4161/cc.6.11.4315.
-
(2007)
Cell Cycle
, vol.6
, pp. 1298-1303
-
-
Perdiguero, E.1
Ruiz-Bonilla, V.2
Serrano, A.L.3
Muñoz-Cánoves, P.4
-
17
-
-
80054722470
-
A muscle-specific p38 MAPK/Mef2/MnSOD pathway regulates stress, motor function, and life span in Drosophila
-
Vrailas-Mortimer A, del Rivero T, Mukherjee S, Nag S, Gaitanidis A, Kadas D, Consoulas C, Duttaroy A, Sanyal S. 2011. A muscle-specific p38 MAPK/Mef2/MnSOD pathway regulates stress, motor function, and life span in Drosophila. Dev. Cell 21:783-795. http://dx.doi.org/10.1016/j.devcel.2011.09.002.
-
(2011)
Dev. Cell
, vol.21
, pp. 783-795
-
-
Vrailas-Mortimer, A.1
del Rivero, T.2
Mukherjee, S.3
Nag, S.4
Gaitanidis, A.5
Kadas, D.6
Consoulas, C.7
Duttaroy, A.8
Sanyal, S.9
-
18
-
-
77957352000
-
Inactivation of VCP/ter94 suppresses retinal pathology caused by misfolded rhodopsin in Drosophila
-
Griciuc A, Aron L, Roux MJ, Klein R, Giangrande A, Ueffing M. 2010. Inactivation of VCP/ter94 suppresses retinal pathology caused by misfolded rhodopsin in Drosophila. PLoS Genet. 6:e1001075. http://dx.doi.org/10.1371/journal.pgen.1001075.
-
(2010)
PLoS Genet
, vol.6
-
-
Griciuc, A.1
Aron, L.2
Roux, M.J.3
Klein, R.4
Giangrande, A.5
Ueffing, M.6
-
19
-
-
84866401324
-
High-resolution protein interaction map of the Drosophila melanogaster p38 mitogen-activated protein kinases reveals limited functional redundancy
-
Belozerov VE, Lin ZY, Gingras AC, McDermott JC, Michael Siu KW. 2012. High-resolution protein interaction map of the Drosophila melanogaster p38 mitogen-activated protein kinases reveals limited functional redundancy. Mol. Cell. Biol. 32:3695-3706. http://dx.doi.org/10.1128 /MCB.00232-12.
-
(2012)
Mol. Cell. Biol.
, vol.32
, pp. 3695-3706
-
-
Belozerov, V.E.1
Lin, Z.Y.2
Gingras, A.C.3
McDermott, J.C.4
Michael Siu, K.W.5
-
20
-
-
77957947158
-
ProHits: integrated software for mass spectrometry-based interaction proteomics
-
Liu G, Zhang J, Larsen B, Stark C, Breitkreutz A, Lin ZY, Breitkreutz BJ, Ding Y, Colwill K, Pasculescu A, Pawson T, Wrana JL, Nesvizhskii AI, Raught B, Tyers M, Gingras AC. 2010. ProHits: integrated software for mass spectrometry-based interaction proteomics. Nat. Biotechnol. 28: 1015-1017. http://dx.doi.org/10.1038/nbt1010-1015.
-
(2010)
Nat. Biotechnol.
, vol.28
, pp. 1015-1017
-
-
Liu, G.1
Zhang, J.2
Larsen, B.3
Stark, C.4
Breitkreutz, A.5
Lin, Z.Y.6
Breitkreutz, B.J.7
Ding, Y.8
Colwill, K.9
Pasculescu, A.10
Pawson, T.11
Wrana, J.L.12
Nesvizhskii, A.I.13
Raught, B.14
Tyers, M.15
Gingras, A.C.16
-
21
-
-
38449115435
-
Studying translational control in Drosophila cell-free systems
-
Gebauer F, Hentze MW. 2007. Studying translational control in Drosophila cell-free systems. Methods Enzymol. 429:23-33. http://dx.doi.org/10.1016/S0076-6879(07)29002-0.
-
(2007)
Methods Enzymol
, vol.429
, pp. 23-33
-
-
Gebauer, F.1
Hentze, M.W.2
-
22
-
-
79955548652
-
An efficient factor-depleted mammalian in vitro translation system
-
Rakotondrafara AM, Hentze MW. 2011. An efficient factor-depleted mammalian in vitro translation system. Nat. Protoc. 6:563-571. http://dx.doi.org/10.1038/nprot.2011.314.
-
(2011)
Nat. Protoc.
, vol.6
, pp. 563-571
-
-
Rakotondrafara, A.M.1
Hentze, M.W.2
-
23
-
-
34948889112
-
Global analyses of mRNA translational control during early Drosophila embryogenesis
-
Qin X, Ahn S, Speed TP, Rubin GM. 2007. Global analyses of mRNA translational control during early Drosophila embryogenesis. Genome Biol. 8:R63. http://dx.doi.org/10.1186/gb-2007-8-4-r63.
-
(2007)
Genome Biol
, vol.8
-
-
Qin, X.1
Ahn, S.2
Speed, T.P.3
Rubin, G.M.4
-
24
-
-
77952480068
-
Specific regulation of noncanonical p38 activation by Hsp90-Cdc37 chaperone complex in cardiomyocyte
-
Ota A, Zhang J, Ping P, Han J, Wang Y. 2010. Specific regulation of noncanonical p38 activation by Hsp90-Cdc37 chaperone complex in cardiomyocyte. Circ. Res. 106:1404-1412. http://dx.doi.org/10.1161 /CIRCRESAHA.109.213769.
-
(2010)
Circ. Res.
, vol.106
, pp. 1404-1412
-
-
Ota, A.1
Zhang, J.2
Ping, P.3
Han, J.4
Wang, Y.5
-
25
-
-
0030894683
-
Activation of the transcription factor MEF2C by the MAP kinase p38 in inflammation
-
Han J, Jiang Y, Li Z, Kravchenko VV, Ulevitch RJ. 1997. Activation of the transcription factor MEF2C by the MAP kinase p38 in inflammation. Nature 386:296-299. http://dx.doi.org/10.1038/386296a0.
-
(1997)
Nature
, vol.386
, pp. 296-299
-
-
Han, J.1
Jiang, Y.2
Li, Z.3
Kravchenko, V.V.4
Ulevitch, R.J.5
-
26
-
-
80053537984
-
RACK1 A multifaceted scaffolding protein: structure and function
-
Adams DR, Ron D, Kiely PA. 2011. RACK1, A multifaceted scaffolding protein: structure and function. Cell Commun. Signal. 9:22. http://dx.doi.org/10.1186/1478-811X-9-22.
-
(2011)
-Cell Commun. Signal
, vol.9
, pp. 22
-
-
Adams, D.R.1
Ron, D.2
Kiely, P.A.3
-
27
-
-
34248525404
-
Scaffold proteins of MAP-kinase modules
-
Dhanasekaran DN, Kashef K, Lee CM, Xu H, Reddy EP. 2007. Scaffold proteins of MAP-kinase modules. Oncogene 26:3185-3202. http://dx.doi.org/10.1038/sj.onc.1210411.
-
(2007)
Oncogene
, vol.26
, pp. 3185-3202
-
-
Dhanasekaran, D.N.1
Kashef, K.2
Lee, C.M.3
Xu, H.4
Reddy, E.P.5
-
28
-
-
34548100280
-
Character-ization of RACK1 function in Drosophila development
-
Kadrmas JL, Smith MA, Pronovost SM, Beckerle MC. 2007. Character-ization of RACK1 function in Drosophila development. Dev. Dyn. 236: 2207-2215. http://dx.doi.org/10.1002/dvdy.21217.
-
(2007)
Dev. Dyn.
, vol.236
, pp. 2207-2215
-
-
Kadrmas, J.L.1
Smith, M.A.2
Pronovost, S.M.3
Beckerle, M.C.4
-
29
-
-
0018938819
-
Differential decrease in protein synthesis by microsomes from aging Drosophila melanogaster
-
Webster GC, Beachell VT, Webster SL. 1980. Differential decrease in protein synthesis by microsomes from aging Drosophila melanogaster. Exp. Gerontol. 15:495-497. http://dx.doi.org/10.1016/0531-5565(80) 90058-3.
-
(1980)
Exp. Gerontol.
, vol.15
, pp. 495-497
-
-
Webster, G.C.1
Beachell, V.T.2
Webster, S.L.3
-
30
-
-
63949084607
-
SUnSET, a nonradioactive method to monitor protein synthesis
-
Schmidt EK, Clavarino G, Ceppi M, Pierre P. 2009. SUnSET, a nonradioactive method to monitor protein synthesis. Nat. Methods 6:275-277. http://dx.doi.org/10.1038/nmeth.1314.
-
(2009)
Nat. Methods
, vol.6
, pp. 275-277
-
-
Schmidt, E.K.1
Clavarino, G.2
Ceppi, M.3
Pierre, P.4
-
31
-
-
79954618679
-
Novel insights into the regulation of skeletal muscle protein synthesis as revealed by a new nonradioactive in vivo technique
-
Goodman CA, Mabrey DM, Frey JW, Miu MH, Schmidt EK, Pierre P, Hornberger TA. 2011. Novel insights into the regulation of skeletal muscle protein synthesis as revealed by a new nonradioactive in vivo technique. FASEB J. 25:1028-1039. http://dx.doi.org/10.1096/fj.10-168799.
-
(2011)
FASEB J
, vol.25
, pp. 1028-1039
-
-
Goodman, C.A.1
Mabrey, D.M.2
Frey, J.W.3
Miu, M.H.4
Schmidt, E.K.5
Pierre, P.6
Hornberger, T.A.7
-
32
-
-
84872361961
-
Phosphorylation of Atg5 by the Gadd45β-MEKK4-p38 pathway inhibits autophagy
-
Keil E, Höcker R, Schuster M, Essmann F, Ueffing N, Hoffman B, Liebermann DA, Pfeffer K, Schulze-Osthoff K, Schmitz I. 2013. Phosphorylation of Atg5 by the Gadd45β-MEKK4-p38 pathway inhibits autophagy. Cell Death Differ. 20:321-332. http://dx.doi.org/10.1038/cdd.2012.129.
-
(2013)
Cell Death Differ
, vol.20
, pp. 321-332
-
-
Keil, E.1
Höcker, R.2
Schuster, M.3
Essmann, F.4
Ueffing, N.5
Hoffman, B.6
Liebermann, D.A.7
Pfeffer, K.8
Schulze-Osthoff, K.9
Schmitz, I.10
-
33
-
-
75649085703
-
Coordinated regulation of autophagy by p38 MAPK through mAtg9 and p38IP
-
Webber JL, Tooze SA. 2010. Coordinated regulation of autophagy by p38 MAPK through mAtg9 and p38IP. EMBO J. 29:27-40. http://dx.doi.org/10.1038/emboj.2009.321.
-
(2010)
EMBO J
, vol.29
, pp. 27-40
-
-
Webber, J.L.1
Tooze, S.A.2
-
34
-
-
44349107112
-
Autophagy induced by Alexander disease-mutant GFAP accumulation is regulated by p38/MAPK and mTOR signaling pathways
-
Tang G, Yue Z, Talloczy Z, Hagemann T, Cho W, Messing A, Sulzer DL, Goldman JE. 2008. Autophagy induced by Alexander disease-mutant GFAP accumulation is regulated by p38/MAPK and mTOR signaling pathways. Hum. Mol. Genet. 17:1540-1555. http://dx.doi.org/10.1093 /hmg/ddn042.
-
(2008)
Hum. Mol. Genet.
, vol.17
, pp. 1540-1555
-
-
Tang, G.1
Yue, Z.2
Talloczy, Z.3
Hagemann, T.4
Cho, W.5
Messing, A.6
Sulzer, D.L.7
Goldman, J.E.8
-
35
-
-
77957852191
-
Regulation of eukaryotic initiation factor 4E (eIF4E) phosphorylation by mitogen-activated protein kinase occurs through modulation of Mnk1-eIF4G interaction
-
Shveygert M, Kaiser C, Bradrick SS, Gromeier M. 2010. Regulation of eukaryotic initiation factor 4E (eIF4E) phosphorylation by mitogen-activated protein kinase occurs through modulation of Mnk1-eIF4G interaction. Mol. Cell. Biol. 30:5160-5167. http://dx.doi.org/10.1128/MCB.00448-10.
-
(2010)
Mol. Cell. Biol.
, vol.30
, pp. 5160-5167
-
-
Shveygert, M.1
Kaiser, C.2
Bradrick, S.S.3
Gromeier, M.4
-
36
-
-
0346243923
-
Release of eIF6 (p27BBP) from the 60S subunit allows 80S ribosome assembly
-
Ceci M, Gaviraghi C, Gorrini C, Sala LA, Offenhäuser N, Marchisio PC, Biffo S. 2003. Release of eIF6 (p27BBP) from the 60S subunit allows 80S ribosome assembly. Nature 426:579-584. http://dx.doi.org/10.1038 /nature02160.
-
(2003)
Nature
, vol.426
, pp. 579-584
-
-
Ceci, M.1
Gaviraghi, C.2
Gorrini, C.3
Sala, L.A.4
Offenhäuser, N.5
Marchisio, P.C.6
Biffo, S.7
-
37
-
-
84863549085
-
Ribosomal RACK1 promotes chemoresistance and growth in human hepatocellular carcinoma
-
Ruan Y, Sun L, Hao Y, Wang L, Xu J, Zhang W, Xie J, Guo L, Zhou L, Yun X, Zhu H, Shen A, Gu J. 2012. Ribosomal RACK1 promotes chemoresistance and growth in human hepatocellular carcinoma. J. Clin. Invest. 122:2554-2566. http://dx.doi.org/10.1172/JCI58488.
-
(2012)
J. Clin. Invest
, vol.122
, pp. 2554-2566
-
-
Ruan, Y.1
Sun, L.2
Hao, Y.3
Wang, L.4
Xu, J.5
Zhang, W.6
Xie, J.7
Guo, L.8
Zhou, L.9
Yun, X.10
Zhu, H.11
Shen, A.12
Gu, J.13
-
38
-
-
4444351205
-
Yeast Asc1p and mammalian RACK1 are functionally orthologous core 40S ribosomal proteins that repress gene expression
-
Gerbasi VR, Weaver CM, Hill S, Friedman DB, Link AJ. 2004. Yeast Asc1p and mammalian RACK1 are functionally orthologous core 40S ribosomal proteins that repress gene expression. Mol. Cell. Biol. 24:8276-8287. http://dx.doi.org/10.1128/MCB.24.18.8276-8287.2004.
-
(2004)
Mol. Cell. Biol
, vol.24
, pp. 8276-8287
-
-
Gerbasi, V.R.1
Weaver, C.M.2
Hill, S.3
Friedman, D.B.4
Link, A.J.5
-
39
-
-
78649472341
-
Receptor for activated C kinase 1 stimulates nascent polypeptidedependent translation arrest
-
Kuroha K, Akamatsu M, Dimitrova L, Ito T, Kato Y, Shirahige K, Inada T. 2010. Receptor for activated C kinase 1 stimulates nascent polypeptidedependent translation arrest. EMBO Rep. 11:956-961. http://dx.doi.org /10.1038/embor.2010.169.
-
(2010)
EMBO Rep
, vol.11
, pp. 956-961
-
-
Kuroha, K.1
Akamatsu, M.2
Dimitrova, L.3
Ito, T.4
Kato, Y.5
Shirahige, K.6
Inada, T.7
-
40
-
-
67649639495
-
The SESA network links duplication of the yeast centrosome with the protein translation machinery
-
Sezen B, Seedorf M, Schiebel E. 2009. The SESA network links duplication of the yeast centrosome with the protein translation machinery. Genes Dev. 23:1559-1570. http://dx.doi.org/10.1101/gad.524209.
-
(2009)
Genes Dev
, vol.23
, pp. 1559-1570
-
-
Sezen, B.1
Seedorf, M.2
Schiebel, E.3
|