Expression of human amyloid precursor protein in the skeletal muscles of Drosophila results in age- and activity-dependent muscle weakness

BMC Physiology

Volumn 11, Issue 1, 2011, Pages

  Kim, Chul ^a   Srivastava, Sapeckshita ^a   Rice, Marian ^b   Godenschwege, Tanja A ^c   Bentley, Brooke ^d   Ravi, Saranya ^b   Shao, Shuang ^b   Woodard, Craig T ^b   Schwartz, Lawrence M ^a,d  

^a UNIVERSITY OF MASSACHUSETTS   (United States)

^b MOUNT HOLYOKE COLLEGE   (United States)

^c FLORIDA ATLANTIC UNIVERSITY   (United States)

^d Pioneer Valley Life Sciences Institute   (United States)

Author keywords

amyloid precursor protein (APP); apoptosis; Drosophila; electron microscopy; mitochondria; muscle; Parkin

Indexed keywords

AMYLOID PRECURSOR PROTEIN; GLASS; HYBRID PROTEIN; PLASTIC;

AGING; ANIMAL; ANIMAL HOUSING; ARTICLE; BIOSYNTHESIS; DISEASE MODEL; DROSOPHILA MELANOGASTER; EXERCISE; FLYING; GANGLION; GENETICS; HUMAN; LACTOSE OPERON; MOTONEURON; MUSCLE; MUSCLE WEAKNESS; NEUROMUSCULAR SYNAPSE; PATHOPHYSIOLOGY; PHYSIOLOGY; TRANSGENE; TRANSGENIC ANIMAL; ULTRASTRUCTURE;

AGING; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; ANIMALS, GENETICALLY MODIFIED; DISEASE MODELS, ANIMAL; DROSOPHILA MELANOGASTER; EXERCISE; FLIGHT, ANIMAL; GANGLIA, INVERTEBRATE; GLASS; HOUSING, ANIMAL; HUMANS; LAC OPERON; MOTOR NEURONS; MUSCLE WEAKNESS; MUSCLES; NEUROMUSCULAR JUNCTION; PLASTICS; RECOMBINANT FUSION PROTEINS; TRANSGENES;

EID: 79954995198     PISSN: None     EISSN: 14726793     Source Type: Journal    
DOI: 10.1186/1472-6793-11-7     Document Type: Article

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