Expression of the inclusion body myopathy 3 mutation in Drosophila depresses myosin function and stability and recapitulates muscle inclusions and weakness

Molecular Biology of the Cell

Volumn 23, Issue 11, 2012, Pages 2057-2065

  Wang, Yang ^a   Melkani, Girish C ^a   Suggs, Jennifer A ^a   Melkani, Anju ^a   Kronert, William A ^a   Cammarato, Anthony ^a,b   Bernstein, Sanford I ^a  

^a SAN DIEGO STATE UNIVERSITY   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE; MUTANT PROTEIN; MYOSIN;

ARTICLE; CELL INCLUSION; CONTROLLED STUDY; DROSOPHILA; ELECTRON MICROSCOPY; GENETIC CODE; HOMOZYGOTE; INCLUSION BODY MYOPATHY; LIGHT SCATTERING; MISSENSE MUTATION; MUSCLE CELL; MUSCLE WEAKNESS; MYOFILAMENT; MYOPATHY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN STABILITY;

ACTINS; AMINO ACID SEQUENCE; ANIMALS; ANIMALS, GENETICALLY MODIFIED; CA(2+) MG(2+)-ATPASE; CONSERVED SEQUENCE; CONTRACTURE; DROSOPHILA MELANOGASTER; HOMOZYGOTE; HUMANS; INCLUSION BODIES; KINETICS; LOCOMOTION; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUSCLE WEAKNESS; MUTANT PROTEINS; MUTATION; MYOFIBRILS; MYOSIN HEAVY CHAINS; MYOSITIS, INCLUSION BODY; OPHTHALMOPLEGIA; PROTEIN STABILITY; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, SECONDARY; TEMPERATURE;

EID: 84861702034     PISSN: 10591524     EISSN: 19394586     Source Type: Journal    
DOI: 10.1091/mbc.E12-02-0120     Document Type: Article

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