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Volumn 522, Issue 4, 2014, Pages 921-936

Electron tomography on γ-aminobutyric acid-ergic synapses reveals a discontinuous postsynaptic network of filaments

Author keywords

aminobutyric acid receptor; Gephyrin; Glycine receptor; Inhibitory synapse; Postsynaptic density

Indexed keywords

GEPHYRIN;

EID: 84892461037     PISSN: 00219967     EISSN: 10969861     Source Type: Journal    
DOI: 10.1002/cne.23453     Document Type: Article
Times cited : (16)

References (73)
  • 1
    • 0027462315 scopus 로고
    • In vivo observations of pre- and postsynaptic changes during the transition from multiple to single innervation at developing neuromuscular junctions
    • Balice-Gordon RJ, Lichtman JW. 1993. In vivo observations of pre- and postsynaptic changes during the transition from multiple to single innervation at developing neuromuscular junctions. J Neurosci 13:834-855.
    • (1993) J Neurosci , vol.13 , pp. 834-855
    • Balice-Gordon, R.J.1    Lichtman, J.W.2
  • 5
    • 0029054571 scopus 로고
    • Postsynaptic gephyrin immunoreactivity exhibits a nearly one-to-one correspondence with gamma-aminobutyric acid-like immunogold-labeled synaptic inputs to sympathetic preganglionic neurons
    • Cabot JB, Bushnell A, Alessi V, Mendell NR. 1995. Postsynaptic gephyrin immunoreactivity exhibits a nearly one-to-one correspondence with gamma-aminobutyric acid-like immunogold-labeled synaptic inputs to sympathetic preganglionic neurons. J Comp Neurol 356:418-432.
    • (1995) J Comp Neurol , vol.356 , pp. 418-432
    • Cabot, J.B.1    Bushnell, A.2    Alessi, V.3    Mendell, N.R.4
  • 7
    • 0023879477 scopus 로고
    • Characterization of the proteins purified with monoclonal antibodies to glutamic acid decarboxylase
    • Chang, Gottlieb 1988. Characterization of the proteins purified with monoclonal antibodies to glutamic acid decarboxylase. J Neurosci. 8:(6):2123-2130.
    • (1988) J Neurosci , vol.8 , Issue.6 , pp. 2123-2130
    • Chang, G.1
  • 8
    • 33748185659 scopus 로고    scopus 로고
    • Cytoskeleton regulation of glycine receptor number at synapses and diffusion in the plasma membrane
    • Charrier C, Ehrensperger MV, Dahan M, Lévi S, Triller A. 2006. Cytoskeleton regulation of glycine receptor number at synapses and diffusion in the plasma membrane. J Neurosci 26:8502-8511.
    • (2006) J Neurosci , vol.26 , pp. 8502-8511
    • Charrier, C.1    Ehrensperger, M.V.2    Dahan, M.3    Lévi, S.4    Triller, A.5
  • 11
    • 58149339624 scopus 로고    scopus 로고
    • Life inside a thin section: tomography
    • Chen X, Winters CA, Reese TS. 2008b. Life inside a thin section: tomography. J Neurosci 28:9321-9327
    • (2008) J Neurosci , vol.28 , pp. 9321-9327
    • Chen, X.1    Winters, C.A.2    Reese, T.S.3
  • 13
    • 0017396421 scopus 로고
    • The structure of postsynaptic densities isolated from dog cerebral cortex
    • Cohen RS, Blomberg F, Berzins F, Siekevitz P. 1977. The structure of postsynaptic densities isolated from dog cerebral cortex. J Cell Biol 74:181-203.
    • (1977) J Cell Biol , vol.74 , pp. 181-203
    • Cohen, R.S.1    Blomberg, F.2    Berzins, F.3    Siekevitz, P.4
  • 14
    • 0014305851 scopus 로고
    • Synaptic patterns on different cell types in the different laminae of the cat visual cortex: an electron microscope study
    • Colonnier M. 1968. Synaptic patterns on different cell types in the different laminae of the cat visual cortex: an electron microscope study. Brain Res 9:268-287.
    • (1968) Brain Res , vol.9 , pp. 268-287
    • Colonnier, M.1
  • 16
    • 0029968898 scopus 로고    scopus 로고
    • Clustering of gephyrin at GABAergic but non glutamatergic synapses in cultured rat hippocampal neurons
    • Craig AM, Banker G, Chang W, McGrath ME, Serpinskaya AS. 1996. Clustering of gephyrin at GABAergic but non glutamatergic synapses in cultured rat hippocampal neurons. J Neurosci 16:3166-3177.
    • (1996) J Neurosci , vol.16 , pp. 3166-3177
    • Craig, A.M.1    Banker, G.2    Chang, W.3    McGrath, M.E.4    Serpinskaya, A.S.5
  • 17
    • 0142116238 scopus 로고    scopus 로고
    • Diffusion dynamics of glycine receptors revealed by single-quantum dot tracking
    • Dahan M, Lévi S, Luccardini C, Rostaing P, Riveau B, Triller A. 2003. Diffusion dynamics of glycine receptors revealed by single-quantum dot tracking. Science 302:442-445.
    • (2003) Science , vol.302 , pp. 442-445
    • Dahan, M.1    Lévi, S.2    Luccardini, C.3    Rostaing, P.4    Riveau, B.5    Triller, A.6
  • 18
    • 0038044682 scopus 로고    scopus 로고
    • A receptors varies during development in cultured hippocampal neurons
    • A receptors varies during development in cultured hippocampal neurons. Mol Cell Neurosci 23:264-278.
    • (2003) Mol Cell Neurosci , vol.23 , pp. 264-278
    • Danglot, L.1    Triller, A.2    Bessis, A.3
  • 19
    • 9144269975 scopus 로고    scopus 로고
    • Morphologically identified glycinergic synapses in the hippocampus
    • Danglot L, Rostaing P, Triller A, Bessis, A. 2004. Morphologically identified glycinergic synapses in the hippocampus. Mol Cell Neurosci 27:394-403.
    • (2004) Mol Cell Neurosci , vol.27 , pp. 394-403
    • Danglot, L.1    Rostaing, P.2    Triller, A.3    Bessis, A.4
  • 20
    • 79960669630 scopus 로고    scopus 로고
    • Inhibitory synapse dynamics: coordinated presynaptic and postsynaptic mobility and the major contribution of recycled vesicles to new synapse formation
    • Dobie FA, Craig AM. 2011. Inhibitory synapse dynamics: coordinated presynaptic and postsynaptic mobility and the major contribution of recycled vesicles to new synapse formation. J Neurosci 31:10481-93.
    • (2011) J Neurosci , vol.31 , pp. 10481-10493
    • Dobie, F.A.1    Craig, A.M.2
  • 21
    • 0031938769 scopus 로고    scopus 로고
    • v2.1, is apposed to astrocytic processes and is associated with inhibitory postsynaptic membranes in hippocampal and cortical principal neurons and inhibitory interneurons
    • v2.1, is apposed to astrocytic processes and is associated with inhibitory postsynaptic membranes in hippocampal and cortical principal neurons and inhibitory interneurons. Neuroscience 84:37-48.
    • (1998) Neuroscience , vol.84 , pp. 37-48
    • Du, J.1    Tao-Cheng, J.H.2    Zerfas, P.3    McBain, C.J.4
  • 23
    • 0029961402 scopus 로고    scopus 로고
    • Prominent expression of two forms of glutamate decarboxylase in the embryonic and early postnatal rat hippocampal formation
    • Dupuy ST, Houser CR. 1996 Prominent expression of two forms of glutamate decarboxylase in the embryonic and early postnatal rat hippocampal formation. J Neurosci 16:6919-6932.
    • (1996) J Neurosci , vol.16 , pp. 6919-6932
    • Dupuy, S.T.1    Houser, C.R.2
  • 24
    • 0028324791 scopus 로고
    • Comparative localization of two forms of glutamic acid decarboxylase and their mRNAs in rat brain supports the concept of functional differences between the forms
    • Esclapez M, Tillakaratne NJK, Kaufman DL, Tobin AJ, Houser CR. 1994. Comparative localization of two forms of glutamic acid decarboxylase and their mRNAs in rat brain supports the concept of functional differences between the forms. J Neurosci 14:1834-1855.
    • (1994) J Neurosci , vol.14 , pp. 1834-1855
    • Esclapez, M.1    Tillakaratne, N.J.K.2    Kaufman, D.L.3    Tobin, A.J.4    Houser, C.R.5
  • 26
    • 0036828550 scopus 로고    scopus 로고
    • Long-term plasticity at GABAergic and glycinergic synapses: mechanisms and functional significance
    • Gaiarsa JL, Caillard O, Ben-Ari, Y. 2002. Long-term plasticity at GABAergic and glycinergic synapses: mechanisms and functional significance. Trends Neurosci 25:564-570.
    • (2002) Trends Neurosci , vol.25 , pp. 564-570
    • Gaiarsa, J.L.1    Caillard, O.2    Ben-Ari, Y.3
  • 27
    • 0032103933 scopus 로고    scopus 로고
    • Localization of the clustering protein gephyrin at GABAergic synapses in the main olfactory bulb of the rat
    • Giustetto M, Kirsch J, Fritschy JM, Cantino D, Sassoè-Pognetto M. 1998. Localization of the clustering protein gephyrin at GABAergic synapses in the main olfactory bulb of the rat. J Comp Neurol 395:231-244.
    • (1998) J Comp Neurol , vol.395 , pp. 231-244
    • Giustetto, M.1    Kirsch, J.2    Fritschy, J.M.3    Cantino, D.4    Sassoè-Pognetto, M.5
  • 28
    • 0001186564 scopus 로고
    • Axo-somatic and axo-dendritic synaptses of the cerebral cortex: an electron microscope study
    • Gray EG. 1959. Axo-somatic and axo-dendritic synaptses of the cerebral cortex: an electron microscope study. J Anat 93:420-433.
    • (1959) J Anat , vol.93 , pp. 420-433
    • Gray, E.G.1
  • 29
    • 33646850883 scopus 로고    scopus 로고
    • Activity-dependent movements of postsynaptic scaffolds at inhibitory synapses
    • Hanus C, Ehrensperger MV, Triller A. 2006. Activity-dependent movements of postsynaptic scaffolds at inhibitory synapses. J Neurosci 26:4586-4595.
    • (2006) J Neurosci , vol.26 , pp. 4586-4595
    • Hanus, C.1    Ehrensperger, M.V.2    Triller, A.3
  • 30
    • 84859760208 scopus 로고    scopus 로고
    • Splice-specific glycine receptor binding, folding, and phosphorylation of the scaffolding protein gephyrin
    • Herweg J, Schwarz G. 2012. Splice-specific glycine receptor binding, folding, and phosphorylation of the scaffolding protein gephyrin. J Biol Chem 287:12645-12656.
    • (2012) J Biol Chem , vol.287 , pp. 12645-12656
    • Herweg, J.1    Schwarz, G.2
  • 32
    • 5044224260 scopus 로고    scopus 로고
    • PDZ domain proteins of synapses
    • Kim E, Sheng M. 2004. PDZ domain proteins of synapses. Nat Rev Neurosci 5:771-781.
    • (2004) Nat Rev Neurosci , vol.5 , pp. 771-781
    • Kim, E.1    Sheng, M.2
  • 33
    • 0027323367 scopus 로고
    • Widespread expression of gephyrin, a putative glycine receptor-tubulin linker protein, in rat brain
    • Kirsch J, Betz H. 1993. Widespread expression of gephyrin, a putative glycine receptor-tubulin linker protein, in rat brain. Brain Res 621:301-310.
    • (1993) Brain Res , vol.621 , pp. 301-310
    • Kirsch, J.1    Betz, H.2
  • 34
    • 0028998303 scopus 로고
    • The postsynaptic localization of the glycine receptor-associated protein gephyrin is regulated by the cytoskeleton
    • Kirsch J, Betz H. 1995. The postsynaptic localization of the glycine receptor-associated protein gephyrin is regulated by the cytoskeleton. J Neurosci 15:4148-4156.
    • (1995) J Neurosci , vol.15 , pp. 4148-4156
    • Kirsch, J.1    Betz, H.2
  • 36
    • 0034284148 scopus 로고    scopus 로고
    • Clustering of inhibitory neurotransmitter receptors at postsynaptic sites: the membrane activation model
    • Kneussel M, Betz H. 2000. Clustering of inhibitory neurotransmitter receptors at postsynaptic sites: the membrane activation model. Trends Neurosci 23:429-435.
    • (2000) Trends Neurosci , vol.23 , pp. 429-435
    • Kneussel, M.1    Betz, H.2
  • 37
    • 0021336819 scopus 로고
    • GABAergic synaptic boutons in the granule cell layer of rate dentate gyrus
    • Kosaka T, Hama K, Wu JY. 1984. GABAergic synaptic boutons in the granule cell layer of rate dentate gyrus. Brain Res 293:353-359.
    • (1984) Brain Res , vol.293 , pp. 353-359
    • Kosaka, T.1    Hama, K.2    Wu, J.Y.3
  • 38
    • 84856775533 scopus 로고    scopus 로고
    • Activity-dependent coordinated mobility of hippocampal inhibitory synapses visualized with presynaptic and postsynaptic tagged-molecular makers
    • Kuriu T, Yanagawa Y, Konishi S. 2012. Activity-dependent coordinated mobility of hippocampal inhibitory synapses visualized with presynaptic and postsynaptic tagged-molecular makers. Mol Cell Neurosci 49:184-195.
    • (2012) Mol Cell Neurosci , vol.49 , pp. 184-195
    • Kuriu, T.1    Yanagawa, Y.2    Konishi, S.3
  • 40
    • 84892456127 scopus 로고    scopus 로고
    • Electron tomography of the GABAergic PSD in dissociated hippocampal cultures. Poster presented at: Neuroscience 2011. 41st Annual Meeting of the Society for Neuroscience, November, 2011, Washington, DC.
    • Linsalata AE, Chen X, Winters CA, Reese TS. 2011.Electron tomography of the GABAergic PSD in dissociated hippocampal cultures. Poster presented at: Neuroscience 2011. 41st Annual Meeting of the Society for Neuroscience, November, 2011, Washington, DC.
    • (2011)
    • Linsalata, A.E.1    Chen, X.2    Winters, C.A.3    Reese, T.S.4
  • 41
    • 0032432056 scopus 로고    scopus 로고
    • Ribosome association contributes to restricting mRNAs to the cell body of hippocamapal neurons
    • Lu Z, McLaren RS, Winters CA, Ralston E. 1998. Ribosome association contributes to restricting mRNAs to the cell body of hippocamapal neurons. Mol Cell Neurosci 12:363-375.
    • (1998) Mol Cell Neurosci , vol.12 , pp. 363-375
    • Lu, Z.1    McLaren, R.S.2    Winters, C.A.3    Ralston, E.4
  • 42
    • 3042818495 scopus 로고    scopus 로고
    • A receptor trafficking, channel activity, and functional plasticity of inhibitory synapses
    • A receptor trafficking, channel activity, and functional plasticity of inhibitory synapses. Pharmacol Ther 102:195-221.
    • (2004) Pharmacol Ther , vol.102 , pp. 195-221
    • Lüscher, B.1    Keller, C.A.2
  • 43
    • 0036305484 scopus 로고    scopus 로고
    • AMPA receptor trafficking and synaptic plasticity
    • Malinow R, Malenka RC. 2002. AMPA receptor trafficking and synaptic plasticity. Annu Rev Neurosci 25:103-126.
    • (2002) Annu Rev Neurosci , vol.25 , pp. 103-126
    • Malinow, R.1    Malenka, R.C.2
  • 45
    • 0016698218 scopus 로고
    • Immunocytochemical localization of glutamate decarboxylase in rat spinal cord
    • McLaughlin BJ, Barber R, Saito K, Roberts E, Wu JY. 1975a. Immunocytochemical localization of glutamate decarboxylase in rat spinal cord. J Comp Neurol 164:305-322.
    • (1975) J Comp Neurol , vol.164 , pp. 305-322
    • McLaughlin, B.J.1    Barber, R.2    Saito, K.3    Roberts, E.4    Wu, J.Y.5
  • 46
    • 0016632638 scopus 로고
    • The fine structural localization of glutamate decarboxylase in developing axonal processes and presynaptic terminals of rodent cerebellum
    • McLaughlin BJ, Wood JG, Saito K, Roberts E, Wu JY. 1975b. The fine structural localization of glutamate decarboxylase in developing axonal processes and presynaptic terminals of rodent cerebellum. Brain Res 85:355-371.
    • (1975) Brain Res , vol.85 , pp. 355-371
    • McLaughlin, B.J.1    Wood, J.G.2    Saito, K.3    Roberts, E.4    Wu, J.Y.5
  • 48
    • 0035112736 scopus 로고    scopus 로고
    • Fast and reversible trapping of surface glycine receptors by gephyrin
    • Meier J, Vannier C, Sergé A, Triller A, Choquet D. 2001. Fast and reversible trapping of surface glycine receptors by gephyrin. Nat Neurosci 4:253-260.
    • (2001) Nat Neurosci , vol.4 , pp. 253-260
    • Meier, J.1    Vannier, C.2    Sergé, A.3    Triller, A.4    Choquet, D.5
  • 49
    • 0029124881 scopus 로고
    • Identification of a gephyrin binding motif on the glycine receptor β subunit
    • Meyer G, Kirsch J, Betz H, Langosch D. 1995. Identification of a gephyrin binding motif on the glycine receptor β subunit. Neuron 15:563-572.
    • (1995) Neuron , vol.15 , pp. 563-572
    • Meyer, G.1    Kirsch, J.2    Betz, H.3    Langosch, D.4
  • 50
    • 0027299482 scopus 로고
    • An immunocytochemical study of glycine and GABA in laminae I-III of rat spinal dorsal horn
    • Mitchell K, Spike RC, Todd AJ. 1993. An immunocytochemical study of glycine and GABA in laminae I-III of rat spinal dorsal horn. J Neurosci 13:2371-2381.
    • (1993) J Neurosci , vol.13 , pp. 2371-2381
    • Mitchell, K.1    Spike, R.C.2    Todd, A.J.3
  • 51
    • 0035319805 scopus 로고    scopus 로고
    • Constructing inhibitory synapses
    • Moss SJ, Smart TG. 2001. Constructing inhibitory synapses. Nat Rev Neurosci 2:240-250.
    • (2001) Nat Rev Neurosci , vol.2 , pp. 240-250
    • Moss, S.J.1    Smart, T.G.2
  • 53
    • 0020405932 scopus 로고
    • Purification by affinity chromatography of the glycine receptor of rat spinal cord
    • Pfeiffer F, Graham D, Betz H. 1982. Purification by affinity chromatography of the glycine receptor of rat spinal cord. J Biol Chem 257:9389-9393.
    • (1982) J Biol Chem , vol.257 , pp. 9389-9393
    • Pfeiffer, F.1    Graham, D.2    Betz, H.3
  • 55
    • 0014085991 scopus 로고
    • Light and electron microscopic observations on the inner plexiform layer of the rabbit retina
    • Raviola G, Raviola E. 1967. Light and electron microscopic observations on the inner plexiform layer of the rabbit retina. Am J Anat 120:402-426.
    • (1967) Am J Anat , vol.120 , pp. 402-426
    • Raviola, G.1    Raviola, E.2
  • 60
    • 0035860322 scopus 로고    scopus 로고
    • Crystal structures of human gephyrin and plant Cnx1 G domains: comparative analysis and functional implications
    • Schwarz G, Schrader N, Mendel RR, Hecht HJ, Schindelin H. 2001. Crystal structures of human gephyrin and plant Cnx1 G domains: comparative analysis and functional implications. J Mol Biol 312:405-418.
    • (2001) J Mol Biol , vol.312 , pp. 405-418
    • Schwarz, G.1    Schrader, N.2    Mendel, R.R.3    Hecht, H.J.4    Schindelin, H.5
  • 61
    • 0037174634 scopus 로고    scopus 로고
    • Postsynaptic signaling and plasticity mechanisms
    • Sheng M, Kim MJ. 2002. Postsynaptic signaling and plasticity mechanisms. Science 298:776-780.
    • (2002) Science , vol.298 , pp. 776-780
    • Sheng, M.1    Kim, M.J.2
  • 63
    • 77956926830 scopus 로고    scopus 로고
    • Kernel bandwidth optimization in spike rate estimation
    • Shimazaki H, Shinomoto S. 2010. Kernel bandwidth optimization in spike rate estimation. J Comput Neurosci 29:171-182.
    • (2010) J Comput Neurosci , vol.29 , pp. 171-182
    • Shimazaki, H.1    Shinomoto, S.2
  • 64
    • 0035816706 scopus 로고    scopus 로고
    • X-ray crystal structure of the trimeric N-terminal domain of gephyrin
    • Sola M, Kneussel M, Heck IS, Betz H, Weissenhorn W. 2001. X-ray crystal structure of the trimeric N-terminal domain of gephyrin. J Biol Chem 276:25294-25301.
    • (2001) J Biol Chem , vol.276 , pp. 25294-25301
    • Sola, M.1    Kneussel, M.2    Heck, I.S.3    Betz, H.4    Weissenhorn, W.5
  • 66
    • 33746445842 scopus 로고    scopus 로고
    • Activity-related redistribution of presynaptic proteins at the active zone
    • Tao-Cheng JH. 2006. Activity-related redistribution of presynaptic proteins at the active zone. Neuroscience 141:1217-1224.
    • (2006) Neuroscience , vol.141 , pp. 1217-1224
    • Tao-Cheng, J.H.1
  • 67
    • 0028801734 scopus 로고
    • The relationship between glycine and gephyrin in synapses of the rat spinal cord
    • Todd AJ, Spike RC, Chong D, Neilson M. 1995. The relationship between glycine and gephyrin in synapses of the rat spinal cord. Eur J Neurosci 7:1-11.
    • (1995) Eur J Neurosci , vol.7 , pp. 1-11
    • Todd, A.J.1    Spike, R.C.2    Chong, D.3    Neilson, M.4
  • 71
    • 0022415961 scopus 로고
    • Distribution of glycine receptors at central synapses: an immunoelectron microscopy study
    • Triller A, Cluzeaud F, Pfeiffer F, Betz H, Korn H. 1985. Distribution of glycine receptors at central synapses: an immunoelectron microscopy study. J Cell Biol 101:683-688.
    • (1985) J Cell Biol , vol.101 , pp. 683-688
    • Triller, A.1    Cluzeaud, F.2    Pfeiffer, F.3    Betz, H.4    Korn, H.5
  • 72
    • 0023245759 scopus 로고
    • Gamma-aminobutyric acid-containing terminals can be apposed to glycine receptors at central synapses
    • Triller A, Cluzeaud F, Korn H. 1987. Gamma-aminobutyric acid-containing terminals can be apposed to glycine receptors at central synapses. J Cell Biol 104:947-956.
    • (1987) J Cell Biol , vol.104 , pp. 947-956
    • Triller, A.1    Cluzeaud, F.2    Korn, H.3
  • 73
    • 0034880831 scopus 로고    scopus 로고
    • The crystal structure of Escherichia coli MoeA and its relationship to the multifunctional protein gephyrin
    • Xiang S, Nichols J, Rajagopalan KV, Schindelin H. 2001. The crystal structure of Escherichia coli MoeA and its relationship to the multifunctional protein gephyrin. Structure 9:299-310.
    • (2001) Structure , vol.9 , pp. 299-310
    • Xiang, S.1    Nichols, J.2    Rajagopalan, K.V.3    Schindelin, H.4


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