Expression of an anti-RNA autoantibody in a mouse model of SLE increases neutrophil and monocyte numbers as well as IFN-I expression

European Journal of Immunology

Volumn 44, Issue 1, 2014, Pages 215-226

  Han, Jin Hwan ^a   Umiker, Benjamin R ^a   Kazimirova, Anastasia A ^a   Fray, Michael ^a   Korgaonkar, Parimal ^b   Selsing, Erik ^a,b   Imanishi Kari, Thereza ^a,b  

^a TUFTS UNIVERSITY   (United States)

^b TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Autoantibody; Fc receptors; Myeloid cells; Systemic lupus erythematosus; Type I interferon (IFN I)

Indexed keywords

ACTIVATION INDUCED CYTIDINE DEAMINASE; AUTOANTIBODY; COMPLEMENT COMPONENT C1Q; FC RECEPTOR; IMMUNOGLOBULIN G2A; IMMUNOGLOBULIN G2B; INTERFERON; RNA ANTIBODY; TOLL LIKE RECEPTOR 7; FCGR3A PROTEIN, HUMAN; IMMUNOGLOBULIN G; MEMBRANE PROTEIN; RNA; TLR7 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY PRODUCTION; ANTIGEN ANTIBODY COMPLEX; ARTICLE; AUTOCRINE EFFECT; B LYMPHOCYTE; BLOOD CELL; BONE MARROW CELL; CELL EXPANSION; CELL MATURATION; CELL POPULATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; EFFECTOR CELL; GENE EXPRESSION; GENE TARGETING; GENETIC RECOMBINATION; HEAVY CHAIN; IMMUNOPATHOGENESIS; LEUKOCYTE COUNT; LIGHT CHAIN; MONOCYTE; MOUSE; NEUTROPHIL; NEUTROPHIL COUNT; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SPLEEN CELL; SYSTEMIC LUPUS ERYTHEMATOSUS; UPREGULATION; ANIMAL; C57BL MOUSE; CELL CULTURE; CELL GROWTH; DISEASE MODEL; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETICS; HUMAN; IMMUNOGLOBULIN GENE; IMMUNOLOGY; METABOLISM; TRANSGENIC MOUSE;

ANIMALS; AUTOANTIBODIES; AUTOCRINE COMMUNICATION; B-LYMPHOCYTES; CELL GROWTH PROCESSES; CELLS, CULTURED; DISEASE MODELS, ANIMAL; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENES, IMMUNOGLOBULIN; HUMANS; IMMUNOGLOBULIN G; INTERFERON TYPE I; LUPUS ERYTHEMATOSUS, SYSTEMIC; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MONOCYTES; NEUTROPHILS; RECEPTORS, IGG; RNA; TOLL-LIKE RECEPTOR 7;

EID: 84892449662     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.201343714     Document Type: Article

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