Combining chemotherapeutic agents and netrin-1 interference potentiates cancer cell death

EMBO Molecular Medicine

Volumn 5, Issue 12, 2013, Pages 1821-1834

  Paradisi, Andrea ^a   Creveaux, Marion ^a   Gibert, Benjamin ^a   Devailly, Guillaume ^a   Redoulez, Emeline ^a   Neves, David ^b   Cleyssac, Elsa ^b   Treilleux, Isabelle ^c   Klein, Christian ^d   Niederfellner, Gerhard ^d   Cassier, Philippe A ^a   Bernet, Agnès ^a,b   Mehlen, Patrick ^a  

^a UNIVERSITÉ DE LYON   (France)

^b Netris Pharma   (France)

^c CENTRE LÉON BÉRARD   (France)

^d ROCHE DIAGNOSTICS GMBH   (Germany)

Author keywords

Cancer therapy; DCC; Dependence receptor; Netrin 1, p53

Indexed keywords

ANTINEOPLASTIC AGENT; CASPASE 3; CISPLATIN; DOXORUBICIN; FLUOROURACIL; NETRIN 1; PACLITAXEL; PROTEIN P53; TRAP NETRIN DCC; TRAP NETRIN UNC5A; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER COMBINATION CHEMOTHERAPY; CANCER INHIBITION; CANCER SIZE; CELL DEATH; CELL SURVIVAL; CHROMATIN IMMUNOPRECIPITATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG POTENTIATION; ENZYME ACTIVATION; FEMALE; FLOW CYTOMETRY; GENE EXPRESSION; GENE SILENCING; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; IMMUNOPRECIPITATION; IN VITRO STUDY; LUNG CANCER; MOUSE; NONHUMAN; OVARY CANCER; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; TREATMENT DURATION; UPREGULATION;

CANCER THERAPY; DCC; DEPENDENCE RECEPTOR; NETRIN-1, P53;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL LINE, TUMOR; CISPLATIN; DOXORUBICIN; FEMALE; FLUOROURACIL; HUMANS; LUNG NEOPLASMS; MICE; MICE, NUDE; NERVE GROWTH FACTORS; RECEPTORS, CELL SURFACE; RNA INTERFERENCE; RNA, SMALL INTERFERING; TRANSPLANTATION, HETEROLOGOUS; TUMOR SUPPRESSOR PROTEIN P53; TUMOR SUPPRESSOR PROTEINS; UP-REGULATION;

EID: 84892430450     PISSN: 17574676     EISSN: 17574684     Source Type: Journal    
DOI: 10.1002/emmm.201302654     Document Type: Article

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