NF-κB inhibition significantly upregulates the norepinephrine transporter system, causes apoptosis in pheochromocytoma cell lines and prevents metastasis in an animal model

International Journal of Cancer

Volumn 131, Issue 10, 2012, Pages 2445-2455

  Pacak, Karel ^a,b   Sirova, Marta ^b   Giubellino, Alessio ^a   Lencesova, Lubomira ^b   Csaderova, Lucia ^c   Laukova, Marcela ^b   Hudecova, Sona ^b   Krizanova, Olga ^b  

^a EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

^b INSTITUTE OF MOLECULAR PHYSIOLOGY AND GENETICS   (Slovakia)

^c INSTITUTE OF CHEMISTRY   (Slovakia)

Author keywords

apoptosis; NF B inhibition; norepinephrine transporter; pheochromocytoma

Indexed keywords

(3 IODOBENZYL)GUANIDINE I 131; CAPSAICIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MESSENGER RNA; NORADRENALIN TRANSPORTER; PEPTIDE ANTIBODY; TRIPTOLIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CANCER INHIBITION; CELL MEMBRANE; CONTROLLED STUDY; DISEASE MODEL; GENE SILENCING; METASTASIS INHIBITION; MOUSE; NONHUMAN; PHEOCHROMOCYTOMA; PHEOCHROMOCYTOMA CELL; PRIORITY JOURNAL; RAT; UPREGULATION;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL LINE, TUMOR; DISEASE MODELS, ANIMAL; DITERPENES; EPOXY COMPOUNDS; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MICE; MICE, NUDE; NEOPLASM METASTASIS; NF-KAPPA B; NOREPINEPHRINE PLASMA MEMBRANE TRANSPORT PROTEINS; PARAGANGLIOMA; PHENANTHRENES; PHEOCHROMOCYTOMA; RATS; RNA INTERFERENCE; TRANSCRIPTION, GENETIC; TUMOR BURDEN;

EID: 84867070588     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.27524     Document Type: Article

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