메뉴 건너뛰기




Volumn 15, Issue 1, 2014, Pages

Generation of SNP datasets for orangutan population genomics using improved reduced-representation sequencing and direct comparisons of SNP calling algorithms

(15)  Greminger, Maja P a   Stölting, Kai N b   Nater, Alexander a   Goossens, Benoit c,d,e   Arora, Natasha a   Bruggmann, Rémy a,f   Patrignani, Andrea a   Nussberger, Beatrice a   Sharma, Reeta g   Kraus, Robert H S h   Ambu, Laurentius N e   Singleton, Ian i,j   Chikhi, Lounes g,k,l   van Schaik, Carel P a   Krützen, Michael a  


Author keywords

Bioinformatics; CLC genomics workbench; GATK; Great apes; Next generation sequencing; Reduced representation libraries; SAMtools; Single nucleotide polymorphisms

Indexed keywords

ALGORITHM; ANIMAL TISSUE; ARTICLE; COMPUTER PROGRAM; CONTROLLED STUDY; DEMOGRAPHY; DNA SEQUENCE; GENE FREQUENCY; GENE SEQUENCE; GENE TECHNOLOGY; GENOMICS; GENOTYPE; HETEROZYGOTE; HOMOZYGOTE; NONHUMAN; ORANG UTAN; POPULATION GENOMICS; REDUCED REPRESENTATION LIBRARY SEQUENCING; SEQUENCE HOMOLOGY; SINGLE NUCLEOTIDE POLYMORPHISM; STATISTICAL BIAS;

EID: 84892408488     PISSN: None     EISSN: 14712164     Source Type: Journal    
DOI: 10.1186/1471-2164-15-16     Document Type: Article
Times cited : (20)

References (73)
  • 1
    • 79951766233 scopus 로고    scopus 로고
    • Single-nucleotide polymorphism (SNP) discovery and applications of SNP genotyping in nonmodel organisms
    • Seeb JE, Carvalho G, Hauser L, Naish K, Roberts S, Seeb LW. Single-nucleotide polymorphism (SNP) discovery and applications of SNP genotyping in nonmodel organisms. Mol Ecol Resour 2011, 11:1-8.
    • (2011) Mol Ecol Resour , vol.11 , pp. 1-8
    • Seeb, J.E.1    Carvalho, G.2    Hauser, L.3    Naish, K.4    Roberts, S.5    Seeb, L.W.6
  • 2
    • 34250659350 scopus 로고    scopus 로고
    • More genes underwent positive selection in chimpanzee evolution than in human evolution
    • 10.1073/pnas.0701705104, 1863478, 17449636
    • Bakewell MA, Shi P, Zhang J. More genes underwent positive selection in chimpanzee evolution than in human evolution. Proc Natl Acad Sci 2007, 104(18):7489-7494. 10.1073/pnas.0701705104, 1863478, 17449636.
    • (2007) Proc Natl Acad Sci , vol.104 , Issue.18 , pp. 7489-7494
    • Bakewell, M.A.1    Shi, P.2    Zhang, J.3
  • 3
    • 77649215825 scopus 로고    scopus 로고
    • Human and Non-human primate genomes share hotspots of positive selection
    • 10.1371/journal.pgen.1000840, 2816677, 20140238
    • Enard D, Depaulis F, Roest Crollius H. Human and Non-human primate genomes share hotspots of positive selection. PLoS Genet 2010, 6(2):e1000840. 10.1371/journal.pgen.1000840, 2816677, 20140238.
    • (2010) PLoS Genet , vol.6 , Issue.2
    • Enard, D.1    Depaulis, F.2    Roest Crollius, H.3
  • 7
    • 77649219524 scopus 로고    scopus 로고
    • Population genomics of parallel adaptation in threespine stickleback using sequenced RAD tags
    • 10.1371/journal.pgen.1000862, 2829049, 20195501
    • Hohenlohe PA, Bassham S, Etter PD, Stiffler N, Johnson EA, Cresko WA. Population genomics of parallel adaptation in threespine stickleback using sequenced RAD tags. PLoS Genet 2010, 6(2):e1000862. 10.1371/journal.pgen.1000862, 2829049, 20195501.
    • (2010) PLoS Genet , vol.6 , Issue.2
    • Hohenlohe, P.A.1    Bassham, S.2    Etter, P.D.3    Stiffler, N.4    Johnson, E.A.5    Cresko, W.A.6
  • 12
    • 68249140383 scopus 로고    scopus 로고
    • The 1001 genomes project for Arabidopsis thaliana
    • 10.1186/gb-2009-10-5-107, 2718507, 19519932
    • Weigel D, Mott R. The 1001 genomes project for Arabidopsis thaliana. Genome Biol 2009, 10(5):107. 10.1186/gb-2009-10-5-107, 2718507, 19519932.
    • (2009) Genome Biol , vol.10 , Issue.5 , pp. 107
    • Weigel, D.1    Mott, R.2
  • 14
    • 84856998493 scopus 로고    scopus 로고
    • 959 Nematode genomes: a semantic wiki for coordinating sequencing projects
    • 10.1093/nar/gkr826, 3245058, 22058131
    • Kumar S, Schiffer PH, Blaxter M. 959 Nematode genomes: a semantic wiki for coordinating sequencing projects. Nucleic Acids Res 2012, 40(D1):D1295-D1300. 10.1093/nar/gkr826, 3245058, 22058131.
    • (2012) Nucleic Acids Res , vol.40 , Issue.D1
    • Kumar, S.1    Schiffer, P.H.2    Blaxter, M.3
  • 16
    • 84863231960 scopus 로고    scopus 로고
    • Signatures of selection in the genomes of commercial and non-commercial chicken breeds
    • 10.1371/journal.pone.0032720, 3287981, 22384281
    • Elferink MG, Megens H-J, Vereijken A, Hu X, Crooijmans RPMA, Groenen MAM. Signatures of selection in the genomes of commercial and non-commercial chicken breeds. PLoS One 2012, 7(2):e32720. 10.1371/journal.pone.0032720, 3287981, 22384281.
    • (2012) PLoS One , vol.7 , Issue.2
    • Elferink, M.G.1    Megens, H.-J.2    Vereijken, A.3    Hu, X.4    Crooijmans, R.P.M.A.5    Groenen, M.A.M.6
  • 18
    • 79956314887 scopus 로고    scopus 로고
    • Genotype and SNP calling from next-generation sequencing data
    • 10.1038/nrg2986, 3593722, 21587300
    • Nielsen R, Paul JS, Albrechtsen A, Song YS. Genotype and SNP calling from next-generation sequencing data. Nat Rev Genet 2011, 12(6):443-451. 10.1038/nrg2986, 3593722, 21587300.
    • (2011) Nat Rev Genet , vol.12 , Issue.6 , pp. 443-451
    • Nielsen, R.1    Paul, J.S.2    Albrechtsen, A.3    Song, Y.S.4
  • 22
    • 79955783956 scopus 로고    scopus 로고
    • A robust, simple genotyping-by-sequencing (GBS) approach for high diversity species
    • 10.1371/journal.pone.0019379, 3087801, 21573248
    • Elshire RJ, Glaubitz JC, Sun Q, Poland JA, Kawamoto K, Buckler ES, Mitchell SE. A robust, simple genotyping-by-sequencing (GBS) approach for high diversity species. PLoS One 2011, 6(5):e19379. 10.1371/journal.pone.0019379, 3087801, 21573248.
    • (2011) PLoS One , vol.6 , Issue.5
    • Elshire, R.J.1    Glaubitz, J.C.2    Sun, Q.3    Poland, J.A.4    Kawamoto, K.5    Buckler, E.S.6    Mitchell, S.E.7
  • 23
    • 79551526853 scopus 로고    scopus 로고
    • Structural variation in the chicken genome identified by paired-end next-generation DNA sequencing of reduced representation libraries
    • 10.1186/1471-2164-12-94, 3039614, 21291514
    • Kerstens H, Crooijmans R, Dibbits B, Vereijken A, Okimoto R, Groenen M. Structural variation in the chicken genome identified by paired-end next-generation DNA sequencing of reduced representation libraries. BMC Genomics 2011, 12(1):94. 10.1186/1471-2164-12-94, 3039614, 21291514.
    • (2011) BMC Genomics , vol.12 , Issue.1 , pp. 94
    • Kerstens, H.1    Crooijmans, R.2    Dibbits, B.3    Vereijken, A.4    Okimoto, R.5    Groenen, M.6
  • 24
    • 75649147867 scopus 로고    scopus 로고
    • A new strategy for genome assembly using short sequence reads and reduced representation libraries
    • 10.1101/gr.097956.109, 2813480, 20123915
    • Young AL, Abaan HO, Zerbino D, Mullikin JC, Birney E, Margulies EH. A new strategy for genome assembly using short sequence reads and reduced representation libraries. Genome Res 2010, 20(2):249-256. 10.1101/gr.097956.109, 2813480, 20123915.
    • (2010) Genome Res , vol.20 , Issue.2 , pp. 249-256
    • Young, A.L.1    Abaan, H.O.2    Zerbino, D.3    Mullikin, J.C.4    Birney, E.5    Margulies, E.H.6
  • 25
    • 84878456756 scopus 로고    scopus 로고
    • Reference-free SNP discovery for the Eurasian beaver from restriction site-associated DNA paired-end data
    • 10.1111/mec.12242, 23432348
    • Senn H, Ogden R, Cezard T, Gharbi K, Iqbal Z, Johnson E, Kamps-Hughes N, Rosell F, McEwing R. Reference-free SNP discovery for the Eurasian beaver from restriction site-associated DNA paired-end data. Mol Ecol 2013, 22(11):3141-3150. 10.1111/mec.12242, 23432348.
    • (2013) Mol Ecol , vol.22 , Issue.11 , pp. 3141-3150
    • Senn, H.1    Ogden, R.2    Cezard, T.3    Gharbi, K.4    Iqbal, Z.5    Johnson, E.6    Kamps-Hughes, N.7    Rosell, F.8    McEwing, R.9
  • 27
    • 79751491452 scopus 로고    scopus 로고
    • Single nucleotide polymorphisms across a species' range: implications for conservation studies of Pacific salmon
    • Seeb LW, Templin WD, Sato S, Abe S, Warheit K, Park JY, Seeb JE. Single nucleotide polymorphisms across a species' range: implications for conservation studies of Pacific salmon. Mol Ecol Resour 2011, 11:195-217.
    • (2011) Mol Ecol Resour , vol.11 , pp. 195-217
    • Seeb, L.W.1    Templin, W.D.2    Sato, S.3    Abe, S.4    Warheit, K.5    Park, J.Y.6    Seeb, J.E.7
  • 28
    • 0034727107 scopus 로고    scopus 로고
    • An SNP map of the human genome generated by reduced representation shotgun sequencing
    • 10.1038/35035083, 11029002
    • Altshuler D, Pollara VJ, Cowles CR, Van Etten WJ, Baldwin J, Linton L, Lander ES. An SNP map of the human genome generated by reduced representation shotgun sequencing. Nature 2000, 407(6803):513-516. 10.1038/35035083, 11029002.
    • (2000) Nature , vol.407 , Issue.6803 , pp. 513-516
    • Altshuler, D.1    Pollara, V.J.2    Cowles, C.R.3    Van Etten, W.J.4    Baldwin, J.5    Linton, L.6    Lander, E.S.7
  • 29
    • 70349574066 scopus 로고    scopus 로고
    • Application of massive parallel sequencing to whole genome SNP discovery in the porcine genome
    • 10.1186/1471-2164-10-374, 2739861, 19674453
    • Amaral A, Megens H-J, Kerstens H, Heuven H, Dibbits B, Crooijmans R, den Dunnen J, Groenen M. Application of massive parallel sequencing to whole genome SNP discovery in the porcine genome. BMC Genomics 2009, 10(1):374. 10.1186/1471-2164-10-374, 2739861, 19674453.
    • (2009) BMC Genomics , vol.10 , Issue.1 , pp. 374
    • Amaral, A.1    Megens, H.-J.2    Kerstens, H.3    Heuven, H.4    Dibbits, B.5    Crooijmans, R.6    den Dunnen, J.7    Groenen, M.8
  • 30
    • 70549092207 scopus 로고    scopus 로고
    • Large scale single nucleotide polymorphism discovery in unsequenced genomes using second generation high throughput sequencing technology: applied to turkey
    • 10.1186/1471-2164-10-479, 2772860, 19835600
    • Kerstens H, Crooijmans R, Veenendaal A, Dibbits B, Chin-A-Woeng T, den Dunnen J, Groenen M. Large scale single nucleotide polymorphism discovery in unsequenced genomes using second generation high throughput sequencing technology: applied to turkey. BMC Genomics 2009, 10(1):479. 10.1186/1471-2164-10-479, 2772860, 19835600.
    • (2009) BMC Genomics , vol.10 , Issue.1 , pp. 479
    • Kerstens, H.1    Crooijmans, R.2    Veenendaal, A.3    Dibbits, B.4    Chin-A-Woeng, T.5    den Dunnen, J.6    Groenen, M.7
  • 31
    • 76749130701 scopus 로고    scopus 로고
    • High-throughput SNP discovery through deep resequencing of a reduced representation library to anchor and orient scaffolds in the soybean whole genome sequence
    • 10.1186/1471-2164-11-38, 2817691, 20078886
    • Hyten D, Cannon S, Song Q, Weeks N, Fickus E, Shoemaker R, Specht J, Farmer A, May G, Cregan P. High-throughput SNP discovery through deep resequencing of a reduced representation library to anchor and orient scaffolds in the soybean whole genome sequence. BMC Genomics 2010, 11(1):38. 10.1186/1471-2164-11-38, 2817691, 20078886.
    • (2010) BMC Genomics , vol.11 , Issue.1 , pp. 38
    • Hyten, D.1    Cannon, S.2    Song, Q.3    Weeks, N.4    Fickus, E.5    Shoemaker, R.6    Specht, J.7    Farmer, A.8    May, G.9    Cregan, P.10
  • 33
    • 58149327065 scopus 로고    scopus 로고
    • SNP discovery in swine by reduced representation and high throughput pyrosequencing
    • 10.1186/1471-2156-9-81, 2612698, 19055830
    • Wiedmann R, Smith T, Nonneman D. SNP discovery in swine by reduced representation and high throughput pyrosequencing. BMC Genet 2008, 9(1):81. 10.1186/1471-2156-9-81, 2612698, 19055830.
    • (2008) BMC Genet , vol.9 , Issue.1 , pp. 81
    • Wiedmann, R.1    Smith, T.2    Nonneman, D.3
  • 34
    • 78751664988 scopus 로고    scopus 로고
    • To pool, or Not to pool?
    • 10.1534/genetics.110.121012, 2940305, 20855575
    • Cutler DJ, Jensen JD. To pool, or Not to pool?. Genetics 2010, 186(1):41-43. 10.1534/genetics.110.121012, 2940305, 20855575.
    • (2010) Genetics , vol.186 , Issue.1 , pp. 41-43
    • Cutler, D.J.1    Jensen, J.D.2
  • 38
    • 77956295988 scopus 로고    scopus 로고
    • The genome analysis toolkit: a mapreduce framework for analyzing next-generation DNA sequencing data
    • 10.1101/gr.107524.110, 2928508, 20644199
    • McKenna A, Hanna M, Banks E, Sivachenko A, Cibulskis K, Kernytsky A, Garimella K, Altshuler D, Gabriel S, Daly M, et al. The genome analysis toolkit: a mapreduce framework for analyzing next-generation DNA sequencing data. Genome Res 2010, 20(9):1297-1303. 10.1101/gr.107524.110, 2928508, 20644199.
    • (2010) Genome Res , vol.20 , Issue.9 , pp. 1297-1303
    • McKenna, A.1    Hanna, M.2    Banks, E.3    Sivachenko, A.4    Cibulskis, K.5    Kernytsky, A.6    Garimella, K.7    Altshuler, D.8    Gabriel, S.9    Daly, M.10
  • 39
    • 79957950801 scopus 로고    scopus 로고
    • SNP detection and genotyping from low-coverage sequencing data on multiple diploid samples
    • 10.1101/gr.113084.110, 3106328, 20980557
    • Le SQ, Durbin R. SNP detection and genotyping from low-coverage sequencing data on multiple diploid samples. Genome Res 2011, 21(6):952-960. 10.1101/gr.113084.110, 3106328, 20980557.
    • (2011) Genome Res , vol.21 , Issue.6 , pp. 952-960
    • Le, S.Q.1    Durbin, R.2
  • 40
    • 77649263292 scopus 로고    scopus 로고
    • Population genetic inference from genomic sequence variation
    • 10.1101/gr.079509.108, 2840988, 20067940
    • Pool JE, Hellmann I, Jensen JD, Nielsen R. Population genetic inference from genomic sequence variation. Genome Res 2010, 20(3):291-300. 10.1101/gr.079509.108, 2840988, 20067940.
    • (2010) Genome Res , vol.20 , Issue.3 , pp. 291-300
    • Pool, J.E.1    Hellmann, I.2    Jensen, J.D.3    Nielsen, R.4
  • 41
    • 29444452921 scopus 로고    scopus 로고
    • Molecular signatures of natural selection
    • 10.1146/annurev.genet.39.073003.112420, 16285858
    • Nielsen R. Molecular signatures of natural selection. Annu Rev Genet 2005, 39(1):197-218. 10.1146/annurev.genet.39.073003.112420, 16285858.
    • (2005) Annu Rev Genet , vol.39 , Issue.1 , pp. 197-218
    • Nielsen, R.1
  • 42
    • 71949101266 scopus 로고    scopus 로고
    • Single nucleotide polymorphism discovery in rainbow trout by deep sequencing of a reduced representation library
    • 10.1186/1471-2164-10-559, 2790473, 19939274
    • Sanchez C, Smith T, Wiedmann R, Vallejo R, Salem M, Yao J, Rexroad C. Single nucleotide polymorphism discovery in rainbow trout by deep sequencing of a reduced representation library. BMC Genomics 2009, 10(1):559. 10.1186/1471-2164-10-559, 2790473, 19939274.
    • (2009) BMC Genomics , vol.10 , Issue.1 , pp. 559
    • Sanchez, C.1    Smith, T.2    Wiedmann, R.3    Vallejo, R.4    Salem, M.5    Yao, J.6    Rexroad, C.7
  • 43
    • 0004084108 scopus 로고    scopus 로고
    • Washington, DC (USA): Smithsonian Books
    • Groves C. Primate Taxonomy 2001, Washington, DC (USA): Smithsonian Books.
    • (2001) Primate Taxonomy
    • Groves, C.1
  • 44
    • 0034354919 scopus 로고    scopus 로고
    • The behavioral ecology and conservation of the orangutan (pongo pygmaeus): a tale of two islands
    • Delgado AR, van Schaik CP. The behavioral ecology and conservation of the orangutan (pongo pygmaeus): a tale of two islands. Evol Anthropol 2000, 9(5):201-218.
    • (2000) Evol Anthropol , vol.9 , Issue.5 , pp. 201-218
    • Delgado, A.R.1    van Schaik, C.P.2
  • 54
    • 33646187369 scopus 로고    scopus 로고
    • Population history, biogeography, and taxonomy of orangutans (Genus: Pongo) based on a population genetic meta-analysis of multiple loci
    • 10.1016/j.jhevol.2005.12.005, 16472840
    • Steiper ME. Population history, biogeography, and taxonomy of orangutans (Genus: Pongo) based on a population genetic meta-analysis of multiple loci. J Hum Evol 2006, 50(5):509-522. 10.1016/j.jhevol.2005.12.005, 16472840.
    • (2006) J Hum Evol , vol.50 , Issue.5 , pp. 509-522
    • Steiper, M.E.1
  • 58
    • 84871611925 scopus 로고    scopus 로고
    • 1000 Genomes project
    • 1000 Genomes project. [http://www.1000genomes.org/analysis.
  • 61
    • 79751509492 scopus 로고    scopus 로고
    • Short reads and nonmodel species: exploring the complexities of next-generation sequence assembly and SNP discovery in the absence of a reference genome
    • Everett MV, Grau ED, Seeb JE. Short reads and nonmodel species: exploring the complexities of next-generation sequence assembly and SNP discovery in the absence of a reference genome. Mol Ecol Resour 2011, 11:93-108.
    • (2011) Mol Ecol Resour , vol.11 , pp. 93-108
    • Everett, M.V.1    Grau, E.D.2    Seeb, J.E.3
  • 62
    • 84869784350 scopus 로고    scopus 로고
    • Two different high throughput sequencing approaches identify thousands of de novo genomic markers for the genetically depleted Bornean elephant
    • 10.1371/journal.pone.0049533, 3504023, 23185354
    • Sharma R, Goossens B, Kun-Rodrigues C, Teixeira T, Othman N, Boone JQ, Jue NK, Obergfell C, O'Neill RJ, Chikhi L. Two different high throughput sequencing approaches identify thousands of de novo genomic markers for the genetically depleted Bornean elephant. PLoS One 2012, 7(11):e49533. 10.1371/journal.pone.0049533, 3504023, 23185354.
    • (2012) PLoS One , vol.7 , Issue.11
    • Sharma, R.1    Goossens, B.2    Kun-Rodrigues, C.3    Teixeira, T.4    Othman, N.5    Boone, J.Q.6    Jue, N.K.7    Obergfell, C.8    O'Neill, R.J.9    Chikhi, L.10
  • 64
    • 13444283975 scopus 로고    scopus 로고
    • Patterns of genetic diversity and migration in increasingly fragmented and declining orang-utan (Pongo pygmaeus) populations from Sabah, Malaysia
    • Goossens B, Chikhi L, Jalil M, Ancrenaz M, Lackman-Ancrenaz I, Mohamed M, Andau P, Bruford MW. Patterns of genetic diversity and migration in increasingly fragmented and declining orang-utan (Pongo pygmaeus) populations from Sabah, Malaysia. Mol Ecol 2005, 14(2):441-456.
    • (2005) Mol Ecol , vol.14 , Issue.2 , pp. 441-456
    • Goossens, B.1    Chikhi, L.2    Jalil, M.3    Ancrenaz, M.4    Lackman-Ancrenaz, I.5    Mohamed, M.6    Andau, P.7    Bruford, M.W.8
  • 65
    • 0036801005 scopus 로고    scopus 로고
    • Population subdivision and gene flow among wild orangutans
    • 10.1007/BF02629605, 12426465
    • Kanthaswamy S, Smith DG. Population subdivision and gene flow among wild orangutans. Primates 2002, 43(4):315-327. 10.1007/BF02629605, 12426465.
    • (2002) Primates , vol.43 , Issue.4 , pp. 315-327
    • Kanthaswamy, S.1    Smith, D.G.2
  • 66
    • 70349506039 scopus 로고    scopus 로고
    • Detecting loci under selection in a hierarchically structured population
    • 10.1038/hdy.2009.74, 19623208
    • Excoffier L, Hofer T, Foll M. Detecting loci under selection in a hierarchically structured population. Heredity 2009, 103(4):285-298. 10.1038/hdy.2009.74, 19623208.
    • (2009) Heredity , vol.103 , Issue.4 , pp. 285-298
    • Excoffier, L.1    Hofer, T.2    Foll, M.3
  • 67
    • 78650059479 scopus 로고    scopus 로고
    • Application of single nucleotide polymorphisms to non-model species: a technical review
    • 10.1111/j.1755-0998.2010.02891.x, 21565101
    • Garvin MR, Saitoh K, Gharrett AJ. Application of single nucleotide polymorphisms to non-model species: a technical review. Mol Ecol Resour 2010, 10(6):915-934. 10.1111/j.1755-0998.2010.02891.x, 21565101.
    • (2010) Mol Ecol Resour , vol.10 , Issue.6 , pp. 915-934
    • Garvin, M.R.1    Saitoh, K.2    Gharrett, A.J.3
  • 68
    • 33644763127 scopus 로고    scopus 로고
    • Approximate bayesian inference reveals evidence for a recent, severe bottleneck in a Netherlands population of Drosophila melanogaster
    • 1456302, 16299396
    • Thornton K, Andolfatto P. Approximate bayesian inference reveals evidence for a recent, severe bottleneck in a Netherlands population of Drosophila melanogaster. Genetics 2006, 172(3):1607-1619. 1456302, 16299396.
    • (2006) Genetics , vol.172 , Issue.3 , pp. 1607-1619
    • Thornton, K.1    Andolfatto, P.2
  • 69
    • 0036196885 scopus 로고    scopus 로고
    • The signature of positive selection at randomly chosen Loci
    • 1462030, 11901132
    • Przeworski M. The signature of positive selection at randomly chosen Loci. Genetics 2002, 160(3):1179-1189. 1462030, 11901132.
    • (2002) Genetics , vol.160 , Issue.3 , pp. 1179-1189
    • Przeworski, M.1
  • 70
    • 0027305597 scopus 로고
    • The effect of deleterious mutations on neutral molecular variation
    • 1205596, 8375663
    • Charlesworth B, Morgan MT, Charlesworth D. The effect of deleterious mutations on neutral molecular variation. Genetics 1993, 134(4):1289-1303. 1205596, 8375663.
    • (1993) Genetics , vol.134 , Issue.4 , pp. 1289-1303
    • Charlesworth, B.1    Morgan, M.T.2    Charlesworth, D.3
  • 71
    • 77951770756 scopus 로고    scopus 로고
    • BEDTools: a flexible suite of utilities for comparing genomic features
    • 10.1093/bioinformatics/btq033, 2832824, 20110278
    • Quinlan AR, Hall IM. BEDTools: a flexible suite of utilities for comparing genomic features. Bioinformatics 2010, 26(6):841-842. 10.1093/bioinformatics/btq033, 2832824, 20110278.
    • (2010) Bioinformatics , vol.26 , Issue.6 , pp. 841-842
    • Quinlan, A.R.1    Hall, I.M.2
  • 72
    • 0033990048 scopus 로고    scopus 로고
    • Primer3 on the WWW for General Users and for Biologist Programmers
    • Totowa, New Jersey, USA: Humana Press, Misener S, Krawetz S
    • Rozen S, Skaletsky H. Primer3 on the WWW for General Users and for Biologist Programmers. Bioinformatics Methods and Protocols, Volume 132 1999, 365-386. Totowa, New Jersey, USA: Humana Press, Misener S, Krawetz S.
    • (1999) Bioinformatics Methods and Protocols, Volume 132 , pp. 365-386
    • Rozen, S.1    Skaletsky, H.2
  • 73
    • 78649738178 scopus 로고    scopus 로고
    • R package 'sm': nonparametric smoothing methods (version 2.2-4)
    • Bowman AW, Azzalini A. R package 'sm': nonparametric smoothing methods (version 2.2-4). 2010
    • (2010)
    • Bowman, A.W.1    Azzalini, A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.