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Volumn 6, Issue 6, 2013, Pages 624-633

Identification of chemicals inducing cardiomyocyte proliferation in developmental stage-specific manner with pluripotent stem cells

Author keywords

Cardiac; Cell proliferation; Embryonic stem cells; Myocytes

Indexed keywords

1 [N,O BIS(5 ISOQUINOLINESULFONYL) N METHYLTYROSYL] 4 PHENYLPIPERAZINE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; BIO; CARDIAC MYOSIN; CHIR 99021; CYCLIN D2; CYCLIN D3; CYCLIN DEPENDENT KINASE INHIBITOR 2B; GLYCOGEN SYNTHASE KINASE 3 INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE P38 INHIBITOR; N [2 [[N [3 (4 CHLOROPHENYL) 2 PROPENYL] N METHYLAMINO]METHYL]PHENYL] N (2 HYDROXYETHYL) 4 METHOXYBENZENESULFONAMIDE; N [5 (3 DIMETHYLAMINOBENZAMIDO) 2 METHYLPHENYL] 4 HYDROXYBENZAMIDE; SU 1498; TROPONIN T; UNCLASSIFIED DRUG;

EID: 84892377400     PISSN: 1942325X     EISSN: 19423268     Source Type: Journal    
DOI: 10.1161/CIRCGENETICS.113.000330     Document Type: Article
Times cited : (49)

References (48)
  • 4
  • 5
    • 33750298315 scopus 로고    scopus 로고
    • FGF1/p38 MAP kinase inhibitor therapy induces cardiomyocyte mitosis, reduces scarring, and rescues function after myocardial infarction
    • Engel FB, Hsieh PC, Lee RT, Keating MT. FGF1/p38 MAP kinase inhibitor therapy induces cardiomyocyte mitosis, reduces scarring, and rescues function after myocardial infarction. Proc Natl Acad Sci U S A. 2006;103:15546-15551.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 15546-15551
    • Engel, F.B.1    Hsieh, P.C.2    Lee, R.T.3    Keating, M.T.4
  • 6
    • 77449131670 scopus 로고    scopus 로고
    • G-CSF promotes the proliferation of developing cardiomyocytes in vivo and in derivation from ESCs and iPSCs
    • Shimoji K, Yuasa S, Onizuka T, Hattori F, Tanaka T, Hara M, et al. G-CSF promotes the proliferation of developing cardiomyocytes in vivo and in derivation from ESCs and iPSCs. Cell Stem Cell. 2010;6:227-237.
    • (2010) Cell Stem Cell , vol.6 , pp. 227-237
    • Shimoji, K.1    Yuasa, S.2    Onizuka, T.3    Hattori, F.4    Tanaka, T.5    Hara, M.6
  • 7
    • 59649110883 scopus 로고    scopus 로고
    • Cardiac fibroblasts regulate myocardial proliferation through beta1 integrin signaling
    • Ieda M, Tsuchihashi T, Ivey KN, Ross RS, Hong TT, Shaw RM, et al. Cardiac fibroblasts regulate myocardial proliferation through beta1 integrin signaling. Dev Cell. 2009;16:233-244.
    • (2009) Dev Cell , vol.16 , pp. 233-244
    • Ieda, M.1    Tsuchihashi, T.2    Ivey, K.N.3    Ross, R.S.4    Hong, T.T.5    Shaw, R.M.6
  • 8
    • 34547691243 scopus 로고    scopus 로고
    • Periostin induces proliferation of differentiated cardiomyocytes and promotes cardiac repair
    • Kühn B, del Monte F, Hajjar RJ, Chang YS, Lebeche D, Arab S, et al. Periostin induces proliferation of differentiated cardiomyocytes and promotes cardiac repair. Nat Med. 2007;13:962-969.
    • (2007) Nat Med , vol.13 , pp. 962-969
    • Kühn, B.1    Del Monte, F.2    Hajjar, R.J.3    Chang, Y.S.4    Lebeche, D.5    Arab, S.6
  • 9
    • 67650569135 scopus 로고    scopus 로고
    • Neuregulin1/ErbB4 signaling induces cardiomyocyte proliferation and repair of heart injury
    • Bersell K, Arab S, Haring B, Kühn B. Neuregulin1/ErbB4 signaling induces cardiomyocyte proliferation and repair of heart injury. Cell. 2009;138:257-270.
    • (2009) Cell , vol.138 , pp. 257-270
    • Bersell, K.1    Arab, S.2    Haring, B.3    Kühn, B.4
  • 10
    • 76249112688 scopus 로고    scopus 로고
    • Gata4 and Gata5 cooperatively regulate cardiac myocyte proliferation in mice
    • Singh MK, Li Y, Li S, Cobb RM, Zhou D, Lu MM, et al. Gata4 and Gata5 cooperatively regulate cardiac myocyte proliferation in mice. J Biol Chem. 2010;285:1765-1772.
    • (2010) J Biol Chem , vol.285 , pp. 1765-1772
    • Singh, M.K.1    Li, Y.2    Li, S.3    Cobb, R.M.4    Zhou, D.5    Lu, M.M.6
  • 11
    • 55549099609 scopus 로고    scopus 로고
    • Transgenic overexpression of Hdac3 in the heart produces increased postnatal cardiac myocyte proliferation but does not induce hypertrophy
    • Trivedi CM, Lu MM, Wang Q, Epstein JA. Transgenic overexpression of Hdac3 in the heart produces increased postnatal cardiac myocyte proliferation but does not induce hypertrophy. J Biol Chem. 2008;283:26484-26489.
    • (2008) J Biol Chem , vol.283 , pp. 26484-26489
    • Trivedi, C.M.1    Lu, M.M.2    Wang, Q.3    Epstein, J.A.4
  • 13
    • 0038010027 scopus 로고    scopus 로고
    • Jumonji downregulates cardiac cell proliferation by repressing cyclin D1 expression
    • Toyoda M, Shirato H, Nakajima K, Kojima M, Takahashi M, Kubota M, et al. Jumonji downregulates cardiac cell proliferation by repressing cyclin D1 expression. Dev Cell. 2003;5:85-97.
    • (2003) Dev Cell , vol.5 , pp. 85-97
    • Toyoda, M.1    Shirato, H.2    Nakajima, K.3    Kojima, M.4    Takahashi, M.5    Kubota, M.6
  • 16
    • 43749104249 scopus 로고    scopus 로고
    • A chemical approach to stem-cell biology and regenerative medicine
    • Xu Y, Shi Y, Ding S. A chemical approach to stem-cell biology and regenerative medicine. Nature. 2008;453:338-344.
    • (2008) Nature. , vol.453 , pp. 338-344
    • Xu, Y.1    Shi, Y.2    Ding, S.3
  • 17
    • 42949139951 scopus 로고    scopus 로고
    • Evaluation of antiangiogenic activity of azumamides by the in vitro vascular organization model using mouse induced pluripotent stem (iPS) cells
    • Nakao Y, Narazaki G, Hoshino T, Maeda S, Yoshida M, Maejima H, et al. Evaluation of antiangiogenic activity of azumamides by the in vitro vascular organization model using mouse induced pluripotent stem (iPS) cells. Bioorg Med Chem Lett. 2008;18:2982-2984.
    • (2008) Bioorg Med Chem Lett , vol.18 , pp. 2982-2984
    • Nakao, Y.1    Narazaki, G.2    Hoshino, T.3    Maeda, S.4    Yoshida, M.5    Maejima, H.6
  • 18
    • 77951975169 scopus 로고    scopus 로고
    • High content screening: Seeing is believing
    • Zanella F, Lorens JB, Link W. High content screening: seeing is believing. Trends Biotechnol. 2010;28:237-245.
    • (2010) Trends Biotechnol , vol.28 , pp. 237-245
    • Zanella, F.1    Lorens, J.B.2    Link, W.3
  • 19
    • 77954605785 scopus 로고    scopus 로고
    • Recent stem cell advances: Induced pluripotent stem cells for disease modeling and stem cell-based regeneration
    • Yoshida Y, Yamanaka S. Recent stem cell advances: induced pluripotent stem cells for disease modeling and stem cell-based regeneration. Circulation. 2010;122:80-87.
    • (2010) Circulation , vol.122 , pp. 80-87
    • Yoshida, Y.1    Yamanaka, S.2
  • 21
    • 84875916922 scopus 로고    scopus 로고
    • Modeling Alzheimer's disease with iPSCs reveals stress phenotypes associated with intracellular Aβ and differential drug responsiveness
    • Kondo T, Asai M, Tsukita K, Kutoku Y, Ohsawa Y, Sunada Y, et al. Modeling Alzheimer's disease with iPSCs reveals stress phenotypes associated with intracellular Aβ and differential drug responsiveness. Cell Stem Cell. 2013;12:487-496.
    • (2013) Cell Stem Cell , vol.12 , pp. 487-496
    • Kondo, T.1    Asai, M.2    Tsukita, K.3    Kutoku, Y.4    Ohsawa, Y.5    Sunada, Y.6
  • 22
    • 34948891467 scopus 로고    scopus 로고
    • Cardiomyocytes derived from human embryonic stem cells in pro-survival factors enhance function of infarcted rat hearts
    • Laflamme MA, Chen KY, Naumova AV, Muskheli V, Fugate JA, Dupras SK, et al. Cardiomyocytes derived from human embryonic stem cells in pro-survival factors enhance function of infarcted rat hearts. Nat Biotechnol. 2007;25:1015-1024.
    • (2007) Nat Biotechnol , vol.25 , pp. 1015-1024
    • Laflamme, M.A.1    Chen, K.Y.2    Naumova, A.V.3    Muskheli, V.4    Fugate, J.A.5    Dupras, S.K.6
  • 23
    • 77955844034 scopus 로고    scopus 로고
    • ES and iPS cell research for cardiovascular regeneration
    • Yamashita JK. ES and iPS cell research for cardiovascular regeneration. Exp Cell Res. 2010;316:2555-2559.
    • (2010) Exp Cell Res. , vol.316 , pp. 2555-2559
    • Yamashita, J.K.1
  • 24
    • 0034597798 scopus 로고    scopus 로고
    • Flk1-positive cells derived from embryonic stem cells serve as vascular progenitors
    • Yamashita J, Itoh H, Hirashima M, Ogawa M, Nishikawa S, Yurugi T, et al. Flk1-positive cells derived from embryonic stem cells serve as vascular progenitors. Nature. 2000;408:92-96.
    • (2000) Nature , vol.408 , pp. 92-96
    • Yamashita, J.1    Itoh, H.2    Hirashima, M.3    Ogawa, M.4    Nishikawa, S.5    Yurugi, T.6
  • 25
    • 24644459320 scopus 로고    scopus 로고
    • Prospective identification of cardiac progenitors by a novel single cell-based cardiomyocyte induction
    • Yamashita JK, Takano M, Hiraoka-Kanie M, Shimazu C, Peishi Y, Yanagi K, et al. Prospective identification of cardiac progenitors by a novel single cell-based cardiomyocyte induction. FASEB J. 2005;19:1534-1536.
    • (2005) FASEB J , vol.19 , pp. 1534-1536
    • Yamashita, J.K.1    Takano, M.2    Hiraoka-Kanie, M.3    Shimazu, C.4    Peishi, Y.5    Yanagi, K.6
  • 26
    • 49649120250 scopus 로고    scopus 로고
    • Directed and systematic differentiation of cardiovascular cells from mouse induced pluripotent stem cells
    • Narazaki G, Uosaki H, Teranishi M, Okita K, Kim B, Matsuoka S, et al. Directed and systematic differentiation of cardiovascular cells from mouse induced pluripotent stem cells. Circulation. 2008;118:498-506.
    • (2008) Circulation. , vol.118 , pp. 498-506
    • Narazaki, G.1    Uosaki, H.2    Teranishi, M.3    Okita, K.4    Kim, B.5    Matsuoka, S.6
  • 28
    • 80051847166 scopus 로고    scopus 로고
    • Efficient and scalable purification of cardiomyocytes from human embryonic and induced pluripotent stem cells by VCAM1 surface expression
    • Uosaki H, Fukushima H, Takeuchi A, Matsuoka S, Nakatsuji N, Yamanaka S, et al. Efficient and scalable purification of cardiomyocytes from human embryonic and induced pluripotent stem cells by VCAM1 surface expression. PLoS One. 2011;6:e23657.
    • (2011) PLoS One. , vol.6
    • Uosaki, H.1    Fukushima, H.2    Takeuchi, A.3    Matsuoka, S.4    Nakatsuji, N.5    Yamanaka, S.6
  • 29
    • 33646269943 scopus 로고    scopus 로고
    • Insulin-like growth factor i secreted from prostate stromal cells mediates tumor-stromal cell interactions of prostate cancer
    • Kawada M, Inoue H, Masuda T, Ikeda D. Insulin-like growth factor I secreted from prostate stromal cells mediates tumor-stromal cell interactions of prostate cancer. Cancer Res. 2006;66:4419-4425.
    • (2006) Cancer Res. , vol.66 , pp. 4419-4425
    • Kawada, M.1    Inoue, H.2    Masuda, T.3    Ikeda, D.4
  • 30
    • 33947116423 scopus 로고    scopus 로고
    • Involvement of protein phosphatase 2A nuclear accumulation and subsequent inactivation of activator protein-1 in leptomycin B-inhibited cyclin D1 expression
    • Tsuchiya A, Tashiro E, Yoshida M, Imoto M. Involvement of protein phosphatase 2A nuclear accumulation and subsequent inactivation of activator protein-1 in leptomycin B-inhibited cyclin D1 expression. Oncogene. 2007;26:1522-1532.
    • (2007) Oncogene , vol.26 , pp. 1522-1532
    • Tsuchiya, A.1    Tashiro, E.2    Yoshida, M.3    Imoto, M.4
  • 31
    • 77952419621 scopus 로고    scopus 로고
    • Regulation of cardiomyocyte polyploidy and multinucleation by CyclinG1
    • Liu Z, Yue S, Chen X, Kubin T, Braun T. Regulation of cardiomyocyte polyploidy and multinucleation by CyclinG1. Circ Res. 2010;106:1498-1506.
    • (2010) Circ Res , vol.106 , pp. 1498-1506
    • Liu, Z.1    Yue, S.2    Chen, X.3    Kubin, T.4    Braun, T.5
  • 32
    • 33748702122 scopus 로고    scopus 로고
    • The GSK-3 inhibitor BIO promotes proliferation in mammalian cardiomyocytes
    • Tseng AS, Engel FB, Keating MT. The GSK-3 inhibitor BIO promotes proliferation in mammalian cardiomyocytes. Chem Biol. 2006;13:957-963.
    • (2006) Chem Biol , vol.13 , pp. 957-963
    • Tseng, A.S.1    Engel, F.B.2    Keating, M.T.3
  • 34
    • 1242294427 scopus 로고    scopus 로고
    • SU1498, an inhibitor of vascular endothelial growth factor receptor 2, causes accumulation of phosphorylated ERK kinases and inhibits their activity in vivo and in vitro
    • Boguslawski G, McGlynn PW, Harvey KA, Kovala AT. SU1498, an inhibitor of vascular endothelial growth factor receptor 2, causes accumulation of phosphorylated ERK kinases and inhibits their activity in vivo and in vitro. J Biol Chem. 2004;279:5716-5724.
    • (2004) J Biol Chem. , vol.279 , pp. 5716-5724
    • Boguslawski, G.1    McGlynn, P.W.2    Harvey, K.A.3    Kovala, A.T.4
  • 35
    • 77957270888 scopus 로고    scopus 로고
    • Neuregulin/ErbB signaling regulates cardiac subtype specification in differentiating human embryonic stem cells
    • Zhu WZ, Xie Y, Moyes KW, Gold JD, Askari B, Laflamme MA. Neuregulin/ErbB signaling regulates cardiac subtype specification in differentiating human embryonic stem cells. Circ Res. 2010;107:776-786.
    • (2010) Circ Res , vol.107 , pp. 776-786
    • Zhu, W.Z.1    Xie, Y.2    Moyes, K.W.3    Gold, J.D.4    Askari, B.5    Laflamme, M.A.6
  • 36
    • 57649198454 scopus 로고    scopus 로고
    • DUSP6 (MKP3) null mice show enhanced ERK1/2 phosphorylation at baseline and increased myocyte proliferation in the heart affecting disease susceptibility
    • Maillet M, Purcell NH, Sargent MA, York AJ, Bueno OF, Molkentin JD. DUSP6 (MKP3) null mice show enhanced ERK1/2 phosphorylation at baseline and increased myocyte proliferation in the heart affecting disease susceptibility. J Biol Chem. 2008;283:31246-31255.
    • (2008) J Biol Chem , vol.283 , pp. 31246-31255
    • Maillet, M.1    Purcell, N.H.2    Sargent, M.A.3    York, A.J.4    Bueno, O.F.5    Molkentin, J.D.6
  • 37
    • 0024455621 scopus 로고
    • Tissue-specific expression of four types of rat calmodulin-dependent protein kinase II mRNAs
    • Tobimatsu T, Fujisawa H. Tissue-specific expression of four types of rat calmodulin-dependent protein kinase II mRNAs. J Biol Chem. 1989;264:17907-17912.
    • (1989) J Biol Chem. , vol.264 , pp. 17907-17912
    • Tobimatsu, T.1    Fujisawa, H.2
  • 38
    • 18844383961 scopus 로고    scopus 로고
    • P38 MAP kinase inhibition enables proliferation of adult mammalian cardiomyocytes
    • Engel FB, Schebesta M, Duong MT, Lu G, Ren S, Madwed JB, et al. p38 MAP kinase inhibition enables proliferation of adult mammalian cardiomyocytes. Genes Dev. 2005;19:1175-1187.
    • (2005) Genes Dev , vol.19 , pp. 1175-1187
    • Engel, F.B.1    Schebesta, M.2    Duong, M.T.3    Lu, G.4    Ren, S.5    Madwed, J.B.6
  • 39
    • 36248937203 scopus 로고    scopus 로고
    • Hyperpolarization-activated cyclic nucleotide-gated channels and T-type calcium channels confer automaticity of embryonic stem cell-derived cardiomyocytes
    • Yanagi K, Takano M, Narazaki G, Uosaki H, Hoshino T, Ishii T, et al. Hyperpolarization-activated cyclic nucleotide-gated channels and T-type calcium channels confer automaticity of embryonic stem cell-derived cardiomyocytes. Stem Cells. 2007;25:2712-2719.
    • (2007) Stem Cells , vol.25 , pp. 2712-2719
    • Yanagi, K.1    Takano, M.2    Narazaki, G.3    Uosaki, H.4    Hoshino, T.5    Ishii, T.6
  • 40
    • 36248966518 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from adult human fibroblasts by defined factors
    • Takahashi K, Tanabe K, Ohnuki M, Narita M, Ichisaka T, Tomoda K, et al. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell. 2007;131:861-872.
    • (2007) Cell , vol.131 , pp. 861-872
    • Takahashi, K.1    Tanabe, K.2    Ohnuki, M.3    Narita, M.4    Ichisaka, T.5    Tomoda, K.6
  • 41
    • 0142074405 scopus 로고    scopus 로고
    • Spatial and temporal patterns of ERK signaling during mouse embryogenesis
    • Corson LB, Yamanaka Y, Lai KM, Rossant J. Spatial and temporal patterns of ERK signaling during mouse embryogenesis. Development. 2003;130:4527-4537.
    • (2003) Development. , vol.130 , pp. 4527-4537
    • Corson, L.B.1    Yamanaka, Y.2    Lai, K.M.3    Rossant, J.4
  • 42
    • 34248210189 scopus 로고    scopus 로고
    • Targeting dual-specificity phosphatases: Manipulating MAP kinase signalling and immune responses
    • Jeffrey KL, Camps M, Rommel C, Mackay CR. Targeting dual-specificity phosphatases: manipulating MAP kinase signalling and immune responses. Nat Rev Drug Discov. 2007;6:391-403.
    • (2007) Nat Rev Drug Discov , vol.6 , pp. 391-403
    • Jeffrey, K.L.1    Camps, M.2    Rommel, C.3    Mackay, C.R.4
  • 43
    • 0034685545 scopus 로고    scopus 로고
    • 2+/calmodulin-dependent kinase II and calcineurin play critical roles in endothelin-1-induced cardiomyocyte hypertrophy
    • 2+/calmodulin-dependent kinase II and calcineurin play critical roles in endothelin-1-induced cardiomyocyte hypertrophy. J Biol Chem. 2000;275:15239-15245.
    • (2000) J Biol Chem. , vol.275 , pp. 15239-15245
    • Zhu, W.1    Zou, Y.2    Shiojima, I.3    Kudoh, S.4    Aikawa, R.5    Hayashi, D.6
  • 44
    • 60549085044 scopus 로고    scopus 로고
    • The delta isoform of CaM kinase II is required for pathological cardiac hypertrophy and remodeling after pressure overload
    • Backs J, Backs T, Neef S, Kreusser MM, Lehmann LH, Patrick DM, et al. The delta isoform of CaM kinase II is required for pathological cardiac hypertrophy and remodeling after pressure overload. Proc Natl Acad Sci U S A. 2009;106:2342-2347.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 2342-2347
    • Backs, J.1    Backs, T.2    Neef, S.3    Kreusser, M.M.4    Lehmann, L.H.5    Patrick, D.M.6
  • 45
    • 84864498547 scopus 로고    scopus 로고
    • Transcriptional regulation of the fetal cardiac gene program
    • Kuwahara K, Nishikimi T, Nakao K. Transcriptional regulation of the fetal cardiac gene program. J Pharmacol Sci. 2012;119:198-203.
    • (2012) J Pharmacol Sci , vol.119 , pp. 198-203
    • Kuwahara, K.1    Nishikimi, T.2    Nakao, K.3
  • 46
    • 34547699399 scopus 로고    scopus 로고
    • Evidence from a genetic fate-mapping study that stem cells refresh adult mammalian cardiomyocytes after injury
    • Hsieh PC, Segers VF, Davis ME, MacGillivray C, Gannon J, Molkentin JD, et al. Evidence from a genetic fate-mapping study that stem cells refresh adult mammalian cardiomyocytes after injury. Nat Med. 2007;13:970-974.
    • (2007) Nat Med , vol.13 , pp. 970-974
    • Hsieh, P.C.1    Segers, V.F.2    Davis, M.E.3    Macgillivray, C.4    Gannon, J.5    Molkentin, J.D.6
  • 48
    • 84861873989 scopus 로고    scopus 로고
    • Pluripotent stem cell-engineered cell sheets reassembled with defined cardiovascular populations ameliorate reduction in infarct heart function through cardiomyocyte-mediated neovascularization
    • Masumoto H, Matsuo T, Yamamizu K, Uosaki H, Narazaki G, Katayama S, et al. Pluripotent stem cell-engineered cell sheets reassembled with defined cardiovascular populations ameliorate reduction in infarct heart function through cardiomyocyte-mediated neovascularization. Stem Cells. 2012;30:1196-1205.
    • (2012) Stem Cells , vol.30 , pp. 1196-1205
    • Masumoto, H.1    Matsuo, T.2    Yamamizu, K.3    Uosaki, H.4    Narazaki, G.5    Katayama, S.6


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