Identifying novel targets in renal cell carcinoma: Design and synthesis of affinity chromatography reagents

Bioorganic and Medicinal Chemistry

Volumn 22, Issue 2, 2014, Pages 711-720

  Bonnet, Muriel ^a   Flanagan, Jack U ^a,b   Chan, Denise A ^c   Giaccia, Amato J ^c   Hay, Michael P ^a,b  

^a UNIVERSITY OF AUCKLAND   (New Zealand)

^b UNIVERSITY OF AUCKLAND   (New Zealand)

^c STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Click chemistry; GLUT 1; Renal cell carcinoma; Sonogashira cross coupling; Von Hippel Lindau factor

Indexed keywords

20 [4 [4 [2 (3 METHYLPHENYL) 1,3 THIAZOL 4 YL] 3 PYRIDINYL] 1H 1,2,3 TRIAZOL 1 YL] 3,6,9,12,15,18 HEXAOXAICOSAN 1 AMMONIUM TRIFLUOROACETATE; 20 [4 [4 [2 (ETHYL 3 METHYLANILINO) 1,3 THIAZOL 4 YL] 3 PYRIDINYL] 1H 1,2,3 TRIAZOL 1 YL] 3,6,9,12,15,18 HEXAOXAICOSAN 1 AMMONIUM TRIFLUOROACETATE; 4 (2 BROMO 4 PYRIDINYL) N ETHYL N (3 METHYLPHENYL) 1,3 THIAZOL 2 AMINE; 4 (3 BROMO 4 PYRIDINYL) N ETHYL N (3 METHYLPHENYL) 1,3 THIAZOL 2 AMINE; 4 (AMINOMETHYL) N (3 PYRIDINYL)BENZAMIDE DIHYDROBROMIDE; 4 (AMINOMETHYL) N PHENYLBENZAMIDE HYDROBROMIDE; 4 [(4 IODOPHENYLSULFONAMIDO)METHYL] N (PYRIDIN 3 YL)BENZAMIDE; 4 [2 [1 (20 AMINO 3,6,9,12,15,18 HEXAOXAICOS 1 YL) 1H 1,2,3 TRIAZOL 4 YL] 4 PYRIDINYL] N (3 METHYLPHENYL) 1,3 THIAZOL 2 AMINE; 4 [2 [1 (20 AMINO 3,6,9,12,15,18 HEXAOXAICOS 1 YL) 1H 1,2,3 TRIAZOL 4 YL] 4 PYRIDINYL] N ETHYL N (3 METHYLPHENYL) 1,3 THIAZOL 2 AMINE; 4 [[[(4 IODOPHENYL)SULFONYL]AMINO]METHYL] N PHENYLBENZAMIDE; 4 [[[[4 (21 AMINO 4,7,10,13,16,19 HEXAOXAHENICOS 1 YL)PHENYL]SULFONYL]AMINO]METHYL] N (3 PYRIDINYL)BENZAMIDE; 4 [[[[4 (21 AMINO 4,7,10,13,16,19 HEXAOXAHENICOS 1 YL)PHENYL]SULFONYL]AMINO]METHYL] N PHENYLBENZAMIDE; 4 [[[[4 (21 AMINO 4,7,10,13,16,19 HEXAOXAHENICOS 1 YN 1 YL)PHENYL]SULFONYL]AMINO]METHYL] N (3 PYRIDINYL)BENZAMIDE; 6 [4 [4 [2 (3 METHYLPHENYL) 1,3 THIAZOL 4 YL] 2 PYRIDINYL] 1H 1,2,3 TRIAZOL 1 YL] 1 HEXANAMMONIUM TRIFLUOROACETATE; BENZAMIDE DERIVATIVE; BENZYL 4 (PYRIDINE 3 YLCARBAMOYL)BENZYLCARBAMATE; N ETHYL 4 (2 ETHYNYL 4 PYRIDINYL) N (3 METHYLPHENYL) 1,3 THIAZOL 2 AMINE; N ETHYL 4 (3 ETHYNYL 4 PYRIDINYL)N (3 METHYLPHENYL) 1,3 THIAZOL 2 AMINE; TERT BUTYL 17 HYDROXY 3,6,9,12,15 PENTAOXAHEPTADEC 1 YLCARBAMATE; TERT BUTYL 21 [4 [[[4 (ANILINOCARBONYL)BENZYL]AMINO]SULFONYL]PHENYL] 3,6,9,12,15,18 HEXAOXAHENICOS 20 YN 1 YLCARBAMATE; TERT BUTYL 21 [4 [[[4 [(3 PYRIDINYLAMINO)CARBONYL]BENZYL]AMINO]SULFONYL]PHENYL] 3,6,9,12,15,18 HEXAOXAHENICOS 1 YLCARBAMATE; TERT BUTYL 21 [4 [[[4 [(3 PYRIDINYLAMINO)CARBONYL]BENZYL]AMINO]SULFONYL]PHENYL] 3,6,9,12,15,18 HEXAOXAHENICOS 20 YN 1 YLCARBAMATE; TERT BUTYL 3,6,9,12,15,18 HEXAOXAHENICOS 20 YN 1 YLCARBAMATE; TERT BUTYL 6 [4 [4 [2 (3 TOLUIDINO) 1,3 THIAZOL 4 YL] 2 PYRIDINYL] 1H 1,2,3 TRIAZOL 1 YL]HEXYLCARBAMATE; UNCLASSIFIED DRUG; 3-PYRIDYLPHENYLSULFONYL BENZAMIDE; 4-PYRIDYLANILINOTHIAZOLE; ANTINEOPLASTIC AGENT; PYRIDINE DERIVATIVE; SULFONE; THIAZOLE DERIVATIVE;

AFFINITY CHROMATOGRAPHY; ARTICLE; CHEMICAL STRUCTURE; CONTROLLED STUDY; DRUG DESIGN; DRUG IDENTIFICATION; DRUG SYNTHESIS; HUMAN; HUMAN CELL; KIDNEY CARCINOMA; MATHEMATICAL MODEL; PHYSICAL CHEMISTRY; STRUCTURE ACTIVITY RELATION; VON HIPPEL LINDAU DISEASE; CARCINOMA, RENAL CELL; CELL PROLIFERATION; CHEMISTRY; DOSE RESPONSE; DRUG EFFECTS; DRUG SCREENING; KIDNEY NEOPLASMS; PATHOLOGY; SYNTHESIS; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS; BENZAMIDES; CARCINOMA, RENAL CELL; CELL LINE, TUMOR; CELL PROLIFERATION; CHROMATOGRAPHY, AFFINITY; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG DESIGN; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; KIDNEY NEOPLASMS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; PYRIDINES; STRUCTURE-ACTIVITY RELATIONSHIP; SULFONES; THIAZOLES;

EID: 84892369712     PISSN: 09680896     EISSN: 14643391     Source Type: Journal    
DOI: 10.1016/j.bmc.2013.12.028     Document Type: Article

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