SCOPUS 정보 검색 플랫폼

Volumn 19, Issue 11, 2011, Pages 3347-3356

SAR studies of 4-pyridyl heterocyclic anilines that selectively induce autophagic cell death in von Hippel-Lindau-deficient renal cell carcinoma cells

(7) Bonnet, Muriel a Flanagan, Jack U a Chan, Denise A b Lai, Edwin W b Nguyen, Phuong b Giaccia, Amato J b Hay, Michael P a

a UNIVERSITY OF AUCKLAND (New Zealand)

b STANFORD UNIVERSITY SCHOOL OF MEDICINE (United States)

Author keywords

Autophagy; Drug design; QSAR; Renal cell carcinoma; Sonogashira; Structure activity relationships; Suzuki Miyaura; von Hippel Lindau

Indexed keywords

2,6 DICHLORO PYRAZINE; 2,6 DICHLORO PYRIMIDINE; 2,6 DICHLOROPYRIDINE; 3 BROMOANILINE; ANILINE DERIVATIVE; BROMOPYRIDINE DERIVATIVE; IODOPYRIDINE DERIVATIVE; PYRIDYL 2 BROMOETHANONE; THIAZOLE DERIVATIVE; UNCLASSIFIED DRUG; VON HIPPEL LINDAU PROTEIN;

ARTICLE; AUTOPHAGY; CANCER INHIBITION; CARCINOMA CELL; CATALYSIS; CELL DEATH; CELL VIABILITY; CLEAR CELL CARCINOMA; COMPARATIVE MOLECULAR FIELD ANALYSIS; CROSS COUPLING REACTION; DRUG CONFORMATION; DRUG STRUCTURE; HUMAN; HUMAN CELL; KIDNEY CARCINOMA; MOLECULAR MODEL; NUCLEOPHILICITY; POLYMERIZATION; SONOGASHIRA REACTION; STRUCTURE ACTIVITY RELATION; SUZUKI REACTION;

ANILINE COMPOUNDS; AUTOPHAGY; CARCINOMA, RENAL CELL; HUMANS; KIDNEY NEOPLASMS; MODELS, MOLECULAR; PYRIDINES; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; THIAZOLES; VON HIPPEL-LINDAU TUMOR SUPPRESSOR PROTEIN;

EID: 79957529163 PISSN: 09680896 EISSN: 14643391 Source Type: Journal
DOI: 10.1016/j.bmc.2011.04.042 Document Type: Article

Times cited : (20)

References (25)

1
- 0032772880
- R.J. Motzer, M. Mazumdar, J. Bacik, W. Berg, A. Amsterdam, and J. Ferrara J. Clin. Oncol. 17 1999 2530
- (1999) J. Clin. Oncol. , vol.17 , pp. 2530
- Motzer, R.J.¹ Mazumdar, M.² Bacik, J.³ Berg, W.⁴ Amsterdam, A.⁵ Ferrara, J.⁶

2
- 3142765935
- M. Murai, and M. Oya Curr. Opin. Urol. 14 2004 229
- (2004) Curr. Opin. Urol. , vol.14 , pp. 229
- Murai, M.¹ Oya, M.²

3
- 0027954044
- J.R. Gnarra, K. Tory, Y. Weng, L. Schmidt, M.H. Wei, H. Li, F. Latif, S. Liu, F. Chen, F.-M. Duh, I. Lubensky, D.R. Duan, C. Florence, R. Pozzatti, M.M. Walther, N.H. Bander, H.B. Grossman, H. Brauch, S. Pomer, J.D. Brooks, W.B. Isaacs, M.I. Lerman, B. Zbar, and W.M. Linehan Nat. Genet. 7 1994 85
- (1994) Nat. Genet. , vol.7 , pp. 85
- Gnarra, J.R.¹ Tory, K.² Weng, Y.³ Schmidt, L.⁴ Wei, M.H.⁵ Li, H.⁶ Latif, F.⁷ Liu, S.⁸ Chen, F.⁹ Duh, F.-M.¹⁰ Lubensky, I.¹¹ Duan, D.R.¹² Florence, C.¹³ Pozzatti, R.¹⁴ Walther, M.M.¹⁵ Bander, N.H.¹⁶ Grossman, H.B.¹⁷ Brauch, H.¹⁸ Pomer, S.¹⁹ Brooks, J.D.²⁰ more..

4
- 16644373473
- W.Y. Kim, and W.G. Kaelin Jr. J. Clin. Oncol. 22 2004 4991
- (2004) J. Clin. Oncol. , vol.22 , pp. 4991
- Kim, W.Y.¹ Kaelin, Jr.W.G.²

5
- 0033587146
- P.H. Maxwell, M.S. Wiesener, G.W. Chang, S.C. Clifford, E.C. Vaux, M.E. Cockman, C.C. Wykoff, C.W. Pugh, E.R. Maher, and P.J. Ratcliffe Nature 399 1999 271
- (1999) Nature , vol.399 , pp. 271
- Maxwell, P.H.¹ Wiesener, M.S.² Chang, G.W.³ Clifford, S.C.⁴ Vaux, E.C.⁵ Cockman, M.E.⁶ Wykoff, C.C.⁷ Pugh, C.W.⁸ Maher, E.R.⁹ Ratcliffe, P.J.¹⁰

6
- 0029785838
- J.R. Gnarra, S. Zhou, M.J. Merrill, J.R. Wagner, A. Krumm, E. Papavassiliou, E.H. Oldfield, R.D. Klausner, and W.M. Linehan Proc. Natl. Acad. Sci. U.S.A. 93 1996 10589
- (1996) Proc. Natl. Acad. Sci. U.S.A. , vol.93 , pp. 10589
- Gnarra, J.R.¹ Zhou, S.² Merrill, M.J.³ Wagner, J.R.⁴ Krumm, A.⁵ Papavassiliou, E.⁶ Oldfield, E.H.⁷ Klausner, R.D.⁸ Linehan, W.M.⁹

7
- 0029785321
- O. Iliopoulos, A.P. Levy, C. Jiang, W.G. Kaelin Jr., and M.A. Goldberg Proc. Natl. Acad. Sci. U.S.A. 93 1996 10595
- (1996) Proc. Natl. Acad. Sci. U.S.A. , vol.93 , pp. 10595
- Iliopoulos, O.¹ Levy, A.P.² Jiang, C.³ Kaelin, Jr.W.G.⁴ Goldberg, M.A.⁵

8
- 0031964099
- B. Knebelmann, S. Ananth, H.T. Cohen, and V.P. Sukhatme Cancer Res. 58 1998 226
- (1998) Cancer Res. , vol.58 , pp. 226
- Knebelmann, B.¹ Ananth, S.² Cohen, H.T.³ Sukhatme, V.P.⁴

9
- 0141828145
- P. Staller, J. Sulitkova, J. Lisztwan, H. Moch, E.J. Oakeley, and W. Krek Nature 425 2003 307
- (2003) Nature , vol.425 , pp. 307
- Staller, P.¹ Sulitkova, J.² Lisztwan, J.³ Moch, H.⁴ Oakeley, E.J.⁵ Krek, W.⁶

10
- 33646365644
- J.T. Erler, K.L. Bennewith, M. Nicolau, N. Dornhofer, C. Kong, Q.T. Le, J.T. Chi, S.S. Jeffrey, and A.J. Giaccia Nature 440 2006 1222
- (2006) Nature , vol.440 , pp. 1222
- Erler, J.T.¹ Bennewith, K.L.² Nicolau, M.³ Dornhofer, N.⁴ Kong, C.⁵ Le, Q.T.⁶ Chi, J.T.⁷ Jeffrey, S.S.⁸ Giaccia, A.J.⁹

11
- 0032085240
- M. Ohh, R.L. Yauch, K.M. Lonergan, J.M. Whaley, A.O. Stemmer-Rachamimov, D.N. Louis, B.J. Gavin, N. Kley, W.G. Kaelin Jr., and O. Iliopoulos Mol. Cell 1 1998 959
- (1998) Mol. Cell , vol.1 , pp. 959
- Ohh, M.¹ Yauch, R.L.² Lonergan, K.M.³ Whaley, J.M.⁴ Stemmer-Rachamimov, A.O.⁵ Louis, D.N.⁶ Gavin, B.J.⁷ Kley, N.⁸ Kaelin, Jr.W.G.⁹ Iliopoulos, O.¹⁰

12
- 0037223823
- A. Hergovich, J. Lisztwan, R. Barry, P. Ballschmieter, and W. Krek Nat. Cell Biol. 5 2003 64
- (2003) Nat. Cell Biol. , vol.5 , pp. 64
- Hergovich, A.¹ Lisztwan, J.² Barry, R.³ Ballschmieter, P.⁴ Krek, W.⁵

13
- 0035941291
- H. Okuda, K. Saitoh, S. Hirai, K. Iwai, Y. Takaki, M. Baba, N. Minato, S. Ohno, and T. Shuin J. Biol. Chem. 276 2001 43611
- (2001) J. Biol. Chem. , vol.276 , pp. 43611
- Okuda, H.¹ Saitoh, K.² Hirai, S.³ Iwai, K.⁴ Takaki, Y.⁵ Baba, M.⁶ Minato, N.⁷ Ohno, S.⁸ Shuin, T.⁹

14
- 0042466570
- X. Na, H.O. Duan, E.M. Messing, S.R. Schoen, C.K. Ryan, P.A. di Sant'Agnese, E.A. Golemis, and G. Wu EMBO J. 22 2003 4249
- (2003) EMBO J. , vol.22 , pp. 4249
- Na, X.¹ Duan, H.O.² Messing, E.M.³ Schoen, S.R.⁴ Ryan, C.K.⁵ Di Sant'Agnese, P.A.⁶ Golemis, E.A.⁷ Wu, G.⁸

15
- 25444497278
- W.G. Kaelin Jr. Nat. Rev. Cancer 5 2005 689
- (2005) Nat. Rev. Cancer , vol.5 , pp. 689
- Kaelin, Jr.W.G.¹

16
- 53649098582
- D.A. Chan, and A.J. Giaccia Cell Cycle 7 2008 2987
- (2008) Cell Cycle , vol.7 , pp. 2987
- Chan, D.A.¹ Giaccia, A.J.²

17
- 45849147350
- S. Turcotte, P.D. Sutphin, D.A. Chan, M.P. Hay, W.A. Denny, and A.J. Giaccia Cancer Cell 14 2008 90
- (2008) Cancer Cell , vol.14 , pp. 90
- Turcotte, S.¹ Sutphin, P.D.² Chan, D.A.³ Hay, M.P.⁴ Denny, W.A.⁵ Giaccia, A.J.⁶

18
- 77951247552
- S. Turcotte, and A.J. Giaccia Curr. Opin. Cell Biol. 22 2010 246
- (2010) Curr. Opin. Cell Biol. , vol.22 , pp. 246
- Turcotte, S.¹ Giaccia, A.J.²

19
- 78650448754
- A. Fleming, T. Noda, T. Yoshimori, and D.C. Rubinstein Nat. Chem. Biol. 7 2011 9
- (2011) Nat. Chem. Biol. , vol.7 , pp. 9
- Fleming, A.¹ Noda, T.² Yoshimori, T.³ Rubinstein, D.C.⁴

20
- 77249159398
- M.P. Hay, S. Turcotte, J.U. Flanagan, M. Bonnet, D.A. Chan, P.D. Sutphin, P. Nguyen, A.J. Giaccia, and W.A. Denny J. Med. Chem. 53 2010 787
- (2010) J. Med. Chem. , vol.53 , pp. 787
- Hay, M.P.¹ Turcotte, S.² Flanagan, J.U.³ Bonnet, M.⁴ Chan, D.A.⁵ Sutphin, P.D.⁶ Nguyen, P.⁷ Giaccia, A.J.⁸ Denny, W.A.⁹

21
- 0040790523
- Molecular hologram QSAR
- T.W. Heritage, and D.R. Lowis Molecular hologram QSAR A.L. Parrill, M.R. Reddy, Rational Drug Design Novel Methodology and Practical Applications ACS Symposium Series Vol. 719 1999 American Chemical Society Washington, DC 212 225 (Pubitemid 129547002)
- (1999) ACS Symposium Series , vol.719 , pp. 212-225
- Heritage, T.W.¹ Lowis, D.R.²

22
- 45849148111
- S. Mahboobi, A. Sellmer, A. Eswayah, S. Elz, A. Uecker, and F.-D. Böhmer Eur. J. Med. Chem. 43 2008 1444
- (2008) Eur. J. Med. Chem. , vol.43 , pp. 1444
- Mahboobi, S.¹ Sellmer, A.² Eswayah, A.³ Elz, S.⁴ Uecker, A.⁵ Böhmer, F.-D.⁶

23
- 4444288154
- F.X. Tavares, S.H. Boucheron, R.J. Griffin, F. Preugschat, S.A. Thomson, T.Y. Wang, and H.-Q. Zhou J. Med. Chem. 47 2004 4716
- (2004) J. Med. Chem. , vol.47 , pp. 4716
- Tavares, F.X.¹ Boucheron, S.H.² Griffin, R.J.³ Preugschat, F.⁴ Thomson, S.A.⁵ Wang, T.Y.⁶ Zhou, H.-Q.⁷

24
- 20544462877
- H. Adams, S.R. Batten, G.M. Davies, M.B. Duriska, J.C. Jeffery, P. Jensen, J. Lu, G.R. Motson, S.J. Coles, M.B. Hursthouse, and M.D. Ward Dalton Trans. 2005 1910
- (2005) Dalton Trans. , pp. 1910
- Adams, H.¹ Batten, S.R.² Davies, G.M.³ Duriska, M.B.⁴ Jeffery, J.C.⁵ Jensen, P.⁶ Lu, J.⁷ Motson, G.R.⁸ Coles, S.J.⁹ Hursthouse, M.B.¹⁰ Ward, M.D.¹¹

25
- 84923549167
- Y. Miki, N. Nakamura, H. Hachiken, and S. Takemura J. Heterocycl. Chem. 26 1989 1739
- (1989) J. Heterocycl. Chem. , vol.26 , pp. 1739
- Miki, Y.¹ Nakamura, N.² Hachiken, H.³ Takemura, S.⁴

* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.