메뉴 건너뛰기




Volumn 141, Issue 3, 2014, Pages 358-367

Remnant cholesterol as a cause of ischemic heart disease: Evidence, definition, measurement, atherogenicity, high risk patients, and present and future treatment

Author keywords

Atherosclerosis; Cardiovascular disease; Causal; Cholesterol; Lipoprotein; Remnants

Indexed keywords

CHOLESTEROL; FISH OIL; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; LOMITAPIDE; LOW DENSITY LIPOPROTEIN CHOLESTEROL; MIPOMERSEN; NICOTINIC ACID; OMEGA 3 FATTY ACID; TRIACYLGLYCEROL;

EID: 84892366435     PISSN: 01637258     EISSN: 1879016X     Source Type: Journal    
DOI: 10.1016/j.pharmthera.2013.11.008     Document Type: Review
Times cited : (183)

References (110)
  • 2
    • 0026065576 scopus 로고
    • Plasma triglyceride and coronary heart disease
    • M.A. Austin Plasma triglyceride and coronary heart disease Arterioscler Thromb 11 1991 2 14
    • (1991) Arterioscler Thromb , vol.11 , pp. 2-14
    • Austin, M.A.1
  • 3
    • 34447520136 scopus 로고    scopus 로고
    • Fasting compared with nonfasting triglycerides and risk of cardiovascular events in women
    • S. Bansal, J.E. Buring, N. Rifai, S. Mora, F.M. Sacks, and P.M. Ridker Fasting compared with nonfasting triglycerides and risk of cardiovascular events in women JAMA 298 2007 309 316
    • (2007) JAMA , vol.298 , pp. 309-316
    • Bansal, S.1    Buring, J.E.2    Rifai, N.3    Mora, S.4    Sacks, F.M.5    Ridker, P.M.6
  • 5
    • 84870297571 scopus 로고    scopus 로고
    • Icosapent ethyl, a pure EPA omega-3 fatty acid: Effects on lipoprotein particle concentration and size in patients with very high triglyceride levels (the MARINE study)
    • H.E. Bays, R.A. Braeckman, C.M. Ballantyne, J.J. Kastelein, J.D. Otvos, and W.G. Stirtan et al. Icosapent ethyl, a pure EPA omega-3 fatty acid: Effects on lipoprotein particle concentration and size in patients with very high triglyceride levels (the MARINE study) J Clin Lipidol 6 2012 565 572
    • (2012) J Clin Lipidol , vol.6 , pp. 565-572
    • Bays, H.E.1    Braeckman, R.A.2    Ballantyne, C.M.3    Kastelein, J.J.4    Otvos, J.D.5    Stirtan, W.G.6
  • 6
    • 0029808302 scopus 로고    scopus 로고
    • Premature atherosclerosis in patients with familial chylomicronemia caused by mutations in the lipoprotein lipase gene
    • P. Benlian, J.L. De Gennes, L. Foubert, H. Zhang, S.E. Gagne, and M. Hayden Premature atherosclerosis in patients with familial chylomicronemia caused by mutations in the lipoprotein lipase gene N Engl J Med 335 1996 848 854
    • (1996) N Engl J Med , vol.335 , pp. 848-854
    • Benlian, P.1    De Gennes, J.L.2    Foubert, L.3    Zhang, H.4    Gagne, S.E.5    Hayden, M.6
  • 8
    • 0002316655 scopus 로고    scopus 로고
    • Familial lipoprotein lipase deficiency, Apo C-II deficiency, and hepatic lipase deficiency
    • C.R. Scriver, A.L. Beaudet, W.S. Sly, D. Valle, 8th ed. Mc-Graw-Hill, Medical Publishing Division
    • J.D. Brunzell, and S.S. Deeb Familial lipoprotein lipase deficiency, Apo C-II deficiency, and hepatic lipase deficiency C.R. Scriver, A.L. Beaudet, W.S. Sly, D. Valle, The metabolic and molecular bases of inherited diseases 8th ed. 2001 Mc-Graw-Hill, Medical Publishing Division 2789 2816
    • (2001) The Metabolic and Molecular Bases of Inherited Diseases , pp. 2789-2816
    • Brunzell, J.D.1    Deeb, S.S.2
  • 10
    • 78549235583 scopus 로고    scopus 로고
    • Safety of anacetrapib in patients with or at high risk for coronary heart disease
    • C.P. Cannon, S. Shah, H.M. Dansky, M. Davidson, E.A. Brinton, and A.M. Gotto et al. Safety of anacetrapib in patients with or at high risk for coronary heart disease N Engl J Med 363 2010 2406 2415
    • (2010) N Engl J Med , vol.363 , pp. 2406-2415
    • Cannon, C.P.1    Shah, S.2    Dansky, H.M.3    Davidson, M.4    Brinton, E.A.5    Gotto, A.M.6
  • 11
    • 0023910325 scopus 로고
    • Reduction of mortality in the Stockholm Ischaemic Heart Disease Secondary Prevention Study by combined treatment with clofibrate and nicotinic acid
    • L.A. Carlson, and G. Rosenhamer Reduction of mortality in the Stockholm Ischaemic Heart Disease Secondary Prevention Study by combined treatment with clofibrate and nicotinic acid Acta Med Scand 223 1988 405 418
    • (1988) Acta Med Scand , vol.223 , pp. 405-418
    • Carlson, L.A.1    Rosenhamer, G.2
  • 12
    • 84881638790 scopus 로고    scopus 로고
    • Long-term effect of high dose omega-3 fatty acid supplementation for secondary prevention of cardiovascular outcomes: A meta-analysis of randomized, double blind, placebo controlled trials
    • M. Casula, D. Soranna, A.L. Catapano, and G. Corrao Long-term effect of high dose omega-3 fatty acid supplementation for secondary prevention of cardiovascular outcomes: A meta-analysis of randomized, double blind, placebo controlled trials Atheroscler Suppl 14 2013 243 251
    • (2013) Atheroscler Suppl , vol.14 , pp. 243-251
    • Casula, M.1    Soranna, D.2    Catapano, A.L.3    Corrao, G.4
  • 13
    • 79958148945 scopus 로고    scopus 로고
    • Triglyceride-rich lipoproteins and high-density lipoprotein cholesterol in patients at high risk of cardiovascular disease: Evidence and guidance for management
    • M.J. Chapman, H.N. Ginsberg, P. Amarenco, F. Andreotti, J. Boren, and A.L. Catapano et al. Triglyceride-rich lipoproteins and high-density lipoprotein cholesterol in patients at high risk of cardiovascular disease: Evidence and guidance for management Eur Heart J 32 2011 1345 1361
    • (2011) Eur Heart J , vol.32 , pp. 1345-1361
    • Chapman, M.J.1    Ginsberg, H.N.2    Amarenco, P.3    Andreotti, F.4    Boren, J.5    Catapano, A.L.6
  • 14
    • 0016630250 scopus 로고
    • Clofibrate, niacin in coronary heart disease
    • Clofibrate, niacin in coronary heart disease JAMA 231 1975 360 381
    • (1975) JAMA , vol.231 , pp. 360-381
  • 15
    • 33846151732 scopus 로고    scopus 로고
    • Inhibition of microsomal triglyceride transfer protein in familial hypercholesterolemia
    • M. Cuchel, L.T. Bloedon, P.O. Szapary, D.M. Kolansky, M.L. Wolfe, and A. Sarkis et al. Inhibition of microsomal triglyceride transfer protein in familial hypercholesterolemia N Engl J Med 356 2007 148 156
    • (2007) N Engl J Med , vol.356 , pp. 148-156
    • Cuchel, M.1    Bloedon, L.T.2    Szapary, P.O.3    Kolansky, D.M.4    Wolfe, M.L.5    Sarkis, A.6
  • 16
    • 84871945617 scopus 로고    scopus 로고
    • Efficacy and safety of a microsomal triglyceride transfer protein inhibitor in patients with homozygous familial hypercholesterolaemia: A single-arm, open-label, phase 3 study
    • M. Cuchel, E.A. Meagher, T.H. du Toit, D.J. Blom, A.D. Marais, and R.A. Hegele et al. Efficacy and safety of a microsomal triglyceride transfer protein inhibitor in patients with homozygous familial hypercholesterolaemia: A single-arm, open-label, phase 3 study Lancet 381 2013 40 46
    • (2013) Lancet , vol.381 , pp. 40-46
    • Cuchel, M.1    Meagher, E.A.2    Du Toit, T.H.3    Blom, D.J.4    Marais, A.D.5    Hegele, R.A.6
  • 17
    • 0029800916 scopus 로고    scopus 로고
    • Stability and instability: Two faces of coronary atherosclerosis. The Paul Dudley White Lecture 1995
    • M.J. Davies Stability and instability: Two faces of coronary atherosclerosis. The Paul Dudley White Lecture 1995 Circulation 94 1996 2013 2020
    • (1996) Circulation , vol.94 , pp. 2013-2020
    • Davies, M.J.1
  • 18
    • 0032076553 scopus 로고    scopus 로고
    • Remnant-like particle cholesterol levels in patients with dysbetalipoproteinemia or coronary artery disease
    • S. Devaraj, G. Vega, R. Lange, S.M. Grundy, and I. Jialal Remnant-like particle cholesterol levels in patients with dysbetalipoproteinemia or coronary artery disease Am J Med 104 1998 445 450
    • (1998) Am J Med , vol.104 , pp. 445-450
    • Devaraj, S.1    Vega, G.2    Lange, R.3    Grundy, S.M.4    Jialal, I.5
  • 21
  • 22
    • 56149115017 scopus 로고    scopus 로고
    • Nonfasting triglycerides and risk of ischemic stroke in the general population
    • J.J. Freiberg, A. Tybjaerg-Hansen, J.S. Jensen, and B.G. Nordestgaard Nonfasting triglycerides and risk of ischemic stroke in the general population JAMA 300 2008 2142 2152
    • (2008) JAMA , vol.300 , pp. 2142-2152
    • Freiberg, J.J.1    Tybjaerg-Hansen, A.2    Jensen, J.S.3    Nordestgaard, B.G.4
  • 23
    • 0033748494 scopus 로고    scopus 로고
    • Context-dependent and invariant associations between lipids, lipoproteins, and apolipoproteins and apolipoprotein e genotype
    • R. Frikke-Schmidt, B.G. Nordestgaard, B. Agerholm-Larsen, P. Schnohr, and A. Tybjærg-Hansen Context-dependent and invariant associations between lipids, lipoproteins, and apolipoproteins and apolipoprotein E genotype J Lipid Res 41 2000 1812 1822
    • (2000) J Lipid Res , vol.41 , pp. 1812-1822
    • Frikke-Schmidt, R.1    Nordestgaard, B.G.2    Agerholm-Larsen, B.3    Schnohr, P.4    Tybjærg-Hansen, A.5
  • 24
    • 0035893334 scopus 로고    scopus 로고
    • Comparison of remnant-like lipoprotein particles in postmenopausal women with and without coronary artery disease and in men with coronary artery disease
    • H. Fukushima, K. Kugiyama, S. Sugiyama, O. Honda, S. Koide, and S. Nakamura et al. Comparison of remnant-like lipoprotein particles in postmenopausal women with and without coronary artery disease and in men with coronary artery disease Am J Cardiol 88 2001 1370 1373
    • (2001) Am J Cardiol , vol.88 , pp. 1370-1373
    • Fukushima, H.1    Kugiyama, K.2    Sugiyama, S.3    Honda, O.4    Koide, S.5    Nakamura, S.6
  • 25
    • 2942611117 scopus 로고    scopus 로고
    • Prognostic value of remnant-like lipoprotein particle levels in patients with coronary artery disease and type II diabetes mellitus
    • H. Fukushima, S. Sugiyama, O. Honda, S. Koide, S. Nakamura, and T. Sakamoto et al. Prognostic value of remnant-like lipoprotein particle levels in patients with coronary artery disease and type II diabetes mellitus J Am Coll Cardiol 43 2004 2219 2224
    • (2004) J Am Coll Cardiol , vol.43 , pp. 2219-2224
    • Fukushima, H.1    Sugiyama, S.2    Honda, O.3    Koide, S.4    Nakamura, S.5    Sakamoto, T.6
  • 26
    • 84863984123 scopus 로고    scopus 로고
    • Gene therapy for lipoprotein lipase deficiency
    • D. Gaudet, J. Methot, and J. Kastelein Gene therapy for lipoprotein lipase deficiency Curr Opin Lipidol 23 2012 310 320
    • (2012) Curr Opin Lipidol , vol.23 , pp. 310-320
    • Gaudet, D.1    Methot, J.2    Kastelein, J.3
  • 28
    • 0001190507 scopus 로고
    • Evaluation of serum lipoprotein and cholesterol measurements as predictors of clinical complications of atherosclerosis; Report of a cooperative study of lipoproteins and atherosclerosis
    • J.W. Gofman, M. Hanig, J.B. Jones, M.A. Lauffer, E.Y. Lawry, and L.A. Lewis et al. Evaluation of serum lipoprotein and cholesterol measurements as predictors of clinical complications of atherosclerosis; report of a cooperative study of lipoproteins and atherosclerosis Circulation 14 1956 691 742
    • (1956) Circulation , vol.14 , pp. 691-742
    • Gofman, J.W.1    Hanig, M.2    Jones, J.B.3    Lauffer, M.A.4    Lawry, E.Y.5    Lewis, L.A.6
  • 30
    • 84862239765 scopus 로고    scopus 로고
    • Recent clinical studies of the effects of lipid-modifying therapies
    • A.M. Gotto Jr., and J.E. Moon Recent clinical studies of the effects of lipid-modifying therapies Am J Cardiol 110 2012 15A 26A
    • (2012) Am J Cardiol , vol.110
    • Gotto, Jr.A.M.1    Moon, J.E.2
  • 31
    • 84884591325 scopus 로고    scopus 로고
    • Pharmacotherapies for lipid modification: Beyond the statins
    • A.M. Gotto Jr., and J.E. Moon Pharmacotherapies for lipid modification: Beyond the statins Nat Rev Cardiol 10 2013 560 570
    • (2013) Nat Rev Cardiol , vol.10 , pp. 560-570
    • Gotto, Jr.A.M.1    Moon, J.E.2
  • 32
    • 84878637167 scopus 로고    scopus 로고
    • Antisense oligonucleotide inhibition of apolipoprotein C-III reduces plasma triglycerides in rodents, nonhuman primates, and humans
    • M.J. Graham, R.G. Lee, T.A. Bell III, W. Fu, A.E. Mullick, and V.J. Alexander et al. Antisense oligonucleotide inhibition of apolipoprotein C-III reduces plasma triglycerides in rodents, nonhuman primates, and humans Circ Res 112 2013 1479 1490
    • (2013) Circ Res , vol.112 , pp. 1479-1490
    • Graham, M.J.1    Lee, R.G.2    Bell III, T.A.3    Fu, W.4    Mullick, A.E.5    Alexander, V.J.6
  • 33
    • 34447633353 scopus 로고    scopus 로고
    • Diabetes mellitus as a prothrombotic condition
    • P.J. Grant Diabetes mellitus as a prothrombotic condition J Intern Med 262 2007 157 172
    • (2007) J Intern Med , vol.262 , pp. 157-172
    • Grant, P.J.1
  • 34
    • 3142729178 scopus 로고    scopus 로고
    • Implications of recent clinical trials for the National Cholesterol Education Program Adult Treatment Panel III guidelines
    • S.M. Grundy, J.I. Cleeman, C.N. Merz, H.B. Brewer Jr., L.T. Clark, and D.B. Hunninghake et al. Implications of recent clinical trials for the National Cholesterol Education Program Adult Treatment Panel III guidelines Circulation 110 2004 227 239
    • (2004) Circulation , vol.110 , pp. 227-239
    • Grundy, S.M.1    Cleeman, J.I.2    Merz, C.N.3    Brewer, Jr.H.B.4    Clark, L.T.5    Hunninghake, D.B.6
  • 35
    • 82955212918 scopus 로고    scopus 로고
    • Establishment of chemiluminescence enzyme immunoassay for apolipoprotein B-48 and its clinical applications for evaluation of impaired chylomicron remnant metabolism
    • H. Hanada, S. Mugii, M. Okubo, I. Maeda, K. Kuwayama, and Y. Hidaka et al. Establishment of chemiluminescence enzyme immunoassay for apolipoprotein B-48 and its clinical applications for evaluation of impaired chylomicron remnant metabolism Clin Chim Acta 413 2012 160 165
    • (2012) Clin Chim Acta , vol.413 , pp. 160-165
    • Hanada, H.1    Mugii, S.2    Okubo, M.3    Maeda, I.4    Kuwayama, K.5    Hidaka, Y.6
  • 36
    • 0033669114 scopus 로고    scopus 로고
    • Remnant lipoproteins as therapeutic targets
    • R.J. Havel Remnant lipoproteins as therapeutic targets Curr Opin Lipidol 11 2000 615 620
    • (2000) Curr Opin Lipidol , vol.11 , pp. 615-620
    • Havel, R.J.1
  • 37
    • 73849123494 scopus 로고    scopus 로고
    • Triglyceride-rich lipoproteins and plasma lipid transport
    • R.J. Havel Triglyceride-rich lipoproteins and plasma lipid transport Arterioscler Thromb Vasc Biol 30 2010 9 19
    • (2010) Arterioscler Thromb Vasc Biol , vol.30 , pp. 9-19
    • Havel, R.J.1
  • 38
    • 0002548590 scopus 로고    scopus 로고
    • Introduction: Structure and metabolism of plasma lipoproteins
    • C.R. Scriver, A.L. Beaudet, W.S. Sly, D. Valle, 8th ed. Mc-Graw-Hill, Medical Publishing Division
    • R.J. Havel, and J.P. Kane Introduction: Structure and metabolism of plasma lipoproteins C.R. Scriver, A.L. Beaudet, W.S. Sly, D. Valle, The metabolic and molecular bases of inherited diseases 8th ed. 2001 Mc-Graw-Hill, Medical Publishing Division 2705 2716
    • (2001) The Metabolic and Molecular Bases of Inherited Diseases , pp. 2705-2716
    • Havel, R.J.1    Kane, J.P.2
  • 39
    • 84877299845 scopus 로고    scopus 로고
    • HPS2-THRIVE randomized placebo-controlled trial in 25 673 high-risk patients of ER niacin/laropiprant: Trial design, pre-specified muscle and liver outcomes, and reasons for stopping study treatment
    • R. Haynes, L. Jiang, J.C. Hopewell, J. Li, F. Chen, and S. Parish et al. HPS2-THRIVE randomized placebo-controlled trial in 25 673 high-risk patients of ER niacin/laropiprant: Trial design, pre-specified muscle and liver outcomes, and reasons for stopping study treatment Eur Heart J 34 2013 1279 1291
    • (2013) Eur Heart J , vol.34 , pp. 1279-1291
    • Haynes, R.1    Jiang, L.2    Hopewell, J.C.3    Li, J.4    Chen, F.5    Parish, S.6
  • 40
    • 70349983266 scopus 로고    scopus 로고
    • A polygenic basis for four classical Fredrickson hyperlipoproteinemia phenotypes that are characterized by hypertriglyceridemia
    • R.A. Hegele, M.R. Ban, N. Hsueh, B.A. Kennedy, H. Cao, and G.Y. Zou et al. A polygenic basis for four classical Fredrickson hyperlipoproteinemia phenotypes that are characterized by hypertriglyceridemia Hum Mol Genet 18 2009 4189 4194
    • (2009) Hum Mol Genet , vol.18 , pp. 4189-4194
    • Hegele, R.A.1    Ban, M.R.2    Hsueh, N.3    Kennedy, B.A.4    Cao, H.5    Zou, G.Y.6
  • 41
    • 0035652186 scopus 로고    scopus 로고
    • Remnant-like particles cholesterol is higher in diabetic patients with coronary artery disease
    • K. Higashi, T. Ito, K. Nakajima, A. Yonemura, H. Nakamura, and F. Ohsuzu Remnant-like particles cholesterol is higher in diabetic patients with coronary artery disease Metabolism 50 2001 1462 1465
    • (2001) Metabolism , vol.50 , pp. 1462-1465
    • Higashi, K.1    Ito, T.2    Nakajima, K.3    Yonemura, A.4    Nakamura, H.5    Ohsuzu, F.6
  • 42
    • 58249128372 scopus 로고    scopus 로고
    • Serum levels of remnant lipoprotein cholesterol and oxidized low-density lipoprotein in patients with coronary artery disease
    • M. Hiki, K. Shimada, H. Ohmura, T. Kiyanagi, A. Kume, and K. Sumiyoshi et al. Serum levels of remnant lipoprotein cholesterol and oxidized low-density lipoprotein in patients with coronary artery disease J Cardiol 53 2009 108 116
    • (2009) J Cardiol , vol.53 , pp. 108-116
    • Hiki, M.1    Shimada, K.2    Ohmura, H.3    Kiyanagi, T.4    Kume, A.5    Sumiyoshi, K.6
  • 43
    • 0029838433 scopus 로고    scopus 로고
    • Plasma triglyceride level is a risk factor for cardiovascular disease independent of high-density lipoprotein cholesterol level: A meta-analysis of population-based prospective studies
    • J.E. Hokanson, and M.A. Austin Plasma triglyceride level is a risk factor for cardiovascular disease independent of high-density lipoprotein cholesterol level: A meta-analysis of population-based prospective studies J Cardiovasc Risk 3 1996 213 219
    • (1996) J Cardiovasc Risk , vol.3 , pp. 213-219
    • Hokanson, J.E.1    Austin, M.A.2
  • 44
    • 15944403233 scopus 로고    scopus 로고
    • Plasma triglycerides and type III hyperlipidemia are independently associated with premature familial coronary artery disease
    • P.N. Hopkins, L.L. Wu, S.C. Hunt, and E.A. Brinton Plasma triglycerides and type III hyperlipidemia are independently associated with premature familial coronary artery disease J Am Coll Cardiol 45 2005 1003 1012
    • (2005) J Am Coll Cardiol , vol.45 , pp. 1003-1012
    • Hopkins, P.N.1    Wu, L.L.2    Hunt, S.C.3    Brinton, E.A.4
  • 46
    • 23244457015 scopus 로고    scopus 로고
    • Are remnant-like particles independent predictors of coronary heart disease incidence? the Honolulu Heart study
    • C. Imke, B.L. Rodriguez, J.S. Grove, J.R. McNamara, C. Waslien, and A.R. Katz et al. Are remnant-like particles independent predictors of coronary heart disease incidence? The Honolulu Heart study Arterioscler Thromb Vasc Biol 25 2005 1718 1722
    • (2005) Arterioscler Thromb Vasc Biol , vol.25 , pp. 1718-1722
    • Imke, C.1    Rodriguez, B.L.2    Grove, J.S.3    McNamara, J.R.4    Waslien, C.5    Katz, A.R.6
  • 47
    • 2542612842 scopus 로고    scopus 로고
    • Remnant-like lipoprotein particles as risk factors for coronary artery disease in elderly patients
    • T. Inoue, T. Uchida, H. Kamishirado, K. Takayanagi, T. Hayashi, and S. Morooka et al. Remnant-like lipoprotein particles as risk factors for coronary artery disease in elderly patients Horm Metab Res 36 2004 298 302
    • (2004) Horm Metab Res , vol.36 , pp. 298-302
    • Inoue, T.1    Uchida, T.2    Kamishirado, H.3    Takayanagi, K.4    Hayashi, T.5    Morooka, S.6
  • 48
    • 79960644031 scopus 로고    scopus 로고
    • Genetic bases of hypertriglyceridemic phenotypes
    • C.T. Johansen, and R.A. Hegele Genetic bases of hypertriglyceridemic phenotypes Curr Opin Lipidol 22 2011 247 253
    • (2011) Curr Opin Lipidol , vol.22 , pp. 247-253
    • Johansen, C.T.1    Hegele, R.A.2
  • 49
    • 78751519853 scopus 로고    scopus 로고
    • Genetic determinants of plasma triglycerides
    • C.T. Johansen, S. Kathiresan, and R.A. Hegele Genetic determinants of plasma triglycerides J Lipid Res 52 2011 189 206
    • (2011) J Lipid Res , vol.52 , pp. 189-206
    • Johansen, C.T.1    Kathiresan, S.2    Hegele, R.A.3
  • 50
    • 80051551063 scopus 로고    scopus 로고
    • An increased burden of common and rare lipid-associated risk alleles contributes to the phenotypic spectrum of hypertriglyceridemia
    • C.T. Johansen, J. Wang, M.B. Lanktree, A.D. McIntyre, M.R. Ban, and R.A. Martins et al. An increased burden of common and rare lipid-associated risk alleles contributes to the phenotypic spectrum of hypertriglyceridemia Arterioscler Thromb Vasc Biol 31 2011 1916 1926
    • (2011) Arterioscler Thromb Vasc Biol , vol.31 , pp. 1916-1926
    • Johansen, C.T.1    Wang, J.2    Lanktree, M.B.3    McIntyre, A.D.4    Ban, M.R.5    Martins, R.A.6
  • 51
    • 84876175810 scopus 로고    scopus 로고
    • Genetically elevated non-fasting triglycerides and calculated remnant cholesterol as causal risk factors for myocardial infarction
    • A.B. Jorgensen, R. Frikke-Schmidt, A.S. West, P. Grande, B.G. Nordestgaard, and A. Tybjaerg-Hansen Genetically elevated non-fasting triglycerides and calculated remnant cholesterol as causal risk factors for myocardial infarction Eur Heart J 34 2013 1826 1833
    • (2013) Eur Heart J , vol.34 , pp. 1826-1833
    • Jorgensen, A.B.1    Frikke-Schmidt, R.2    West, A.S.3    Grande, P.4    Nordestgaard, B.G.5    Tybjaerg-Hansen, A.6
  • 52
    • 77952708442 scopus 로고    scopus 로고
    • Effects of fibrates on cardiovascular outcomes: A systematic review and meta-analysis
    • M. Jun, C. Foote, J. Lv, B. Neal, A. Patel, and S.J. Nicholls et al. Effects of fibrates on cardiovascular outcomes: A systematic review and meta-analysis Lancet 375 2010 1875 1884
    • (2010) Lancet , vol.375 , pp. 1875-1884
    • Jun, M.1    Foote, C.2    Lv, J.3    Neal, B.4    Patel, A.5    Nicholls, S.J.6
  • 53
    • 0035135827 scopus 로고    scopus 로고
    • Remnant lipoproteins are related to intima-media thickness of the carotid artery independently of LDL cholesterol and plasma triglycerides
    • F. Karpe, S. Boquist, R. Tang, G.M. Bond, F.U. De, and A. Hamsten Remnant lipoproteins are related to intima-media thickness of the carotid artery independently of LDL cholesterol and plasma triglycerides J Lipid Res 42 2001 17 21
    • (2001) J Lipid Res , vol.42 , pp. 17-21
    • Karpe, F.1    Boquist, S.2    Tang, R.3    Bond, G.M.4    De, F.U.5    Hamsten, A.6
  • 54
    • 38649132270 scopus 로고    scopus 로고
    • Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans
    • S. Kathiresan, O. Melander, C. Guiducci, A. Surti, N.P. Burtt, and M.J. Rieder et al. Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans Nat Genet 40 2008 189 197
    • (2008) Nat Genet , vol.40 , pp. 189-197
    • Kathiresan, S.1    Melander, O.2    Guiducci, C.3    Surti, A.4    Burtt, N.P.5    Rieder, M.J.6
  • 55
    • 5644285309 scopus 로고    scopus 로고
    • Human tribbles, a protein family controlling mitogen-activated protein kinase cascades
    • E. Kiss-Toth, S.M. Bagstaff, H.Y. Sung, V. Jozsa, C. Dempsey, and J.C. Caunt et al. Human tribbles, a protein family controlling mitogen-activated protein kinase cascades J Biol Chem 279 2004 42703 42708
    • (2004) J Biol Chem , vol.279 , pp. 42703-42708
    • Kiss-Toth, E.1    Bagstaff, S.M.2    Sung, H.Y.3    Jozsa, V.4    Dempsey, C.5    Caunt, J.C.6
  • 56
    • 0034660437 scopus 로고    scopus 로고
    • Plasminogen-activator inhibitor type 1 and coronary artery disease
    • H.P. Kohler, and P.J. Grant Plasminogen-activator inhibitor type 1 and coronary artery disease N Engl J Med 342 2000 1792 1801
    • (2000) N Engl J Med , vol.342 , pp. 1792-1801
    • Kohler, H.P.1    Grant, P.J.2
  • 57
    • 79955582390 scopus 로고    scopus 로고
    • Assessment and clinical relevance of non-fasting and postprandial triglycerides: An expert panel statement
    • G.D. Kolovou, D.P. Mikhailidis, J. Kovar, D. Lairon, B.G. Nordestgaard, and T.C. Ooi et al. Assessment and clinical relevance of non-fasting and postprandial triglycerides: An expert panel statement Curr Vasc Pharmacol 9 2011 258 270
    • (2011) Curr Vasc Pharmacol , vol.9 , pp. 258-270
    • Kolovou, G.D.1    Mikhailidis, D.P.2    Kovar, J.3    Lairon, D.4    Nordestgaard, B.G.5    Ooi, T.C.6
  • 58
    • 84871674237 scopus 로고    scopus 로고
    • Lipoprotein(a): Resurrected by genetics
    • F. Kronenberg, and G. Utermann Lipoprotein(a): Resurrected by genetics J Intern Med 273 2013 6 30
    • (2013) J Intern Med , vol.273 , pp. 6-30
    • Kronenberg, F.1    Utermann, G.2
  • 59
    • 0033535977 scopus 로고    scopus 로고
    • Remnant lipoprotein levels in fasting serum predict coronary events in patients with coronary artery disease
    • K. Kugiyama, H. Doi, K. Takazoe, H. Kawano, H. Soejima, and Y. Mizuno et al. Remnant lipoprotein levels in fasting serum predict coronary events in patients with coronary artery disease Circulation 99 1999 2858 2860
    • (1999) Circulation , vol.99 , pp. 2858-2860
    • Kugiyama, K.1    Doi, H.2    Takazoe, K.3    Kawano, H.4    Soejima, H.5    Mizuno, Y.6
  • 60
    • 84861128254 scopus 로고    scopus 로고
    • Efficacy of omega-3 fatty acid supplements (eicosapentaenoic acid and docosahexaenoic acid) in the secondary prevention of cardiovascular disease: A meta-analysis of randomized, double-blind, placebo-controlled trials
    • S.M. Kwak, S.K. Myung, Y.J. Lee, and H.G. Seo Efficacy of omega-3 fatty acid supplements (eicosapentaenoic acid and docosahexaenoic acid) in the secondary prevention of cardiovascular disease: A meta-analysis of randomized, double-blind, placebo-controlled trials Arch Intern Med 172 2012 686 694
    • (2012) Arch Intern Med , vol.172 , pp. 686-694
    • Kwak, S.M.1    Myung, S.K.2    Lee, Y.J.3    Seo, H.G.4
  • 61
    • 40749133780 scopus 로고    scopus 로고
    • Plasma levels of HDL subpopulations and remnant lipoproteins predict the extent of angiographically-defined coronary artery disease in postmenopausal women
    • S. Lamon-Fava, D.M. Herrington, D.M. Reboussin, M. Sherman, K.V. Horvath, and L.A. Cupples et al. Plasma levels of HDL subpopulations and remnant lipoproteins predict the extent of angiographically-defined coronary artery disease in postmenopausal women Arterioscler Thromb Vasc Biol 28 2008 575 579
    • (2008) Arterioscler Thromb Vasc Biol , vol.28 , pp. 575-579
    • Lamon-Fava, S.1    Herrington, D.M.2    Reboussin, D.M.3    Sherman, M.4    Horvath, K.V.5    Cupples, L.A.6
  • 62
    • 79959356255 scopus 로고    scopus 로고
    • Nonfasting cholesterol and triglycerides and association with risk of myocardial infarction and total mortality: The Copenhagen City Heart Study with 31 years of follow-up
    • A. Langsted, J.J. Freiberg, A. Tybjaerg-Hansen, P. Schnohr, G.B. Jensen, and B.G. Nordestgaard Nonfasting cholesterol and triglycerides and association with risk of myocardial infarction and total mortality: The Copenhagen City Heart Study with 31 years of follow-up J Intern Med 270 2011 65 75
    • (2011) J Intern Med , vol.270 , pp. 65-75
    • Langsted, A.1    Freiberg, J.J.2    Tybjaerg-Hansen, A.3    Schnohr, P.4    Jensen, G.B.5    Nordestgaard, B.G.6
  • 63
    • 84872679028 scopus 로고    scopus 로고
    • The current state of niacin in cardiovascular disease prevention: A systematic review and meta-regression
    • P.M. Lavigne, and R.H. Karas The current state of niacin in cardiovascular disease prevention: A systematic review and meta-regression J Am Coll Cardiol 61 2013 440 446
    • (2013) J Am Coll Cardiol , vol.61 , pp. 440-446
    • Lavigne, P.M.1    Karas, R.H.2
  • 64
    • 84885729848 scopus 로고    scopus 로고
    • Current Phase II proprotein convertase subtilisin/kexin 9 inhibitor therapies for dyslipidemia
    • P. Lee, and R.A. Hegele Current Phase II proprotein convertase subtilisin/kexin 9 inhibitor therapies for dyslipidemia Expert Opin Investig Drugs 22 2013 1411 1423
    • (2013) Expert Opin Investig Drugs , vol.22 , pp. 1411-1423
    • Lee, P.1    Hegele, R.A.2
  • 65
    • 33846012847 scopus 로고    scopus 로고
    • Liver heparan sulfate proteoglycans mediate clearance of triglyceride-rich lipoproteins independently of LDL receptor family members
    • J.P. MacArthur, J.R. Bishop, K.I. Stanford, L. Wang, A. Bensadoun, and J.L. Witztum et al. Liver heparan sulfate proteoglycans mediate clearance of triglyceride-rich lipoproteins independently of LDL receptor family members J Clin Invest 117 2007 153 164
    • (2007) J Clin Invest , vol.117 , pp. 153-164
    • MacArthur, J.P.1    Bishop, J.R.2    Stanford, K.I.3    Wang, L.4    Bensadoun, A.5    Witztum, J.L.6
  • 66
    • 0031848478 scopus 로고    scopus 로고
    • Predictive value of remnant-like particles cholesterol/high-density lipoprotein cholesterol ratio as a new indicator of coronary artery disease
    • H. Masuoka, K. Ishikura, S. Kamei, T. Obe, T. Seko, and K. Okuda et al. Predictive value of remnant-like particles cholesterol/high-density lipoprotein cholesterol ratio as a new indicator of coronary artery disease Am Heart J 136 1998 226 230
    • (1998) Am Heart J , vol.136 , pp. 226-230
    • Masuoka, H.1    Ishikura, K.2    Kamei, S.3    Obe, T.4    Seko, T.5    Okuda, K.6
  • 67
    • 0034222861 scopus 로고    scopus 로고
    • Predictive value of remnant-like particle cholesterol as an indicator of coronary artery stenosis in patients with normal serum triglyceride levels
    • H. Masuoka, S. Kamei, M. Ozaki, A. Kawasaki, U. Shintani, and M. Ito et al. Predictive value of remnant-like particle cholesterol as an indicator of coronary artery stenosis in patients with normal serum triglyceride levels Intern Med 39 2000 540 546
    • (2000) Intern Med , vol.39 , pp. 540-546
    • Masuoka, H.1    Kamei, S.2    Ozaki, M.3    Kawasaki, A.4    Shintani, U.5    Ito, M.6
  • 68
    • 0033971682 scopus 로고    scopus 로고
    • Association of remnant-like particle cholesterol with coronary artery disease in patients with normal total cholesterol levels
    • H. Masuoka, S. Kamei, H. Wagayama, M. Ozaki, A. Kawasaki, and T. Tanaka et al. Association of remnant-like particle cholesterol with coronary artery disease in patients with normal total cholesterol levels Am Heart J 139 2000 305 310
    • (2000) Am Heart J , vol.139 , pp. 305-310
    • Masuoka, H.1    Kamei, S.2    Wagayama, H.3    Ozaki, M.4    Kawasaki, A.5    Tanaka, T.6
  • 69
    • 0035177104 scopus 로고    scopus 로고
    • Remnant-like particle (RLP) cholesterol is an independent cardiovascular disease risk factor in women: Results from the Framingham Heart Study
    • J.R. McNamara, P.K. Shah, K. Nakajima, L.A. Cupples, P.W. Wilson, and J.M. Ordovas et al. Remnant-like particle (RLP) cholesterol is an independent cardiovascular disease risk factor in women: Results from the Framingham Heart Study Atherosclerosis 154 2001 229 236
    • (2001) Atherosclerosis , vol.154 , pp. 229-236
    • McNamara, J.R.1    Shah, P.K.2    Nakajima, K.3    Cupples, L.A.4    Wilson, P.W.5    Ordovas, J.M.6
  • 70
    • 2542584599 scopus 로고    scopus 로고
    • High remnant lipoprotein levels in patients with variant angina
    • K. Miwa, T. Makita, K. Ishii, N. Okuda, and A. Taniguchi High remnant lipoprotein levels in patients with variant angina Clin Cardiol 27 2004 338 342
    • (2004) Clin Cardiol , vol.27 , pp. 338-342
    • Miwa, K.1    Makita, T.2    Ishii, K.3    Okuda, N.4    Taniguchi, A.5
  • 71
    • 52149109922 scopus 로고    scopus 로고
    • Fasting compared with nonfasting lipids and apolipoproteins for predicting incident cardiovascular events
    • S. Mora, N. Rifai, J.E. Buring, and P.M. Ridker Fasting compared with nonfasting lipids and apolipoproteins for predicting incident cardiovascular events Circulation 118 2008 993 1001
    • (2008) Circulation , vol.118 , pp. 993-1001
    • Mora, S.1    Rifai, N.2    Buring, J.E.3    Ridker, P.M.4
  • 73
    • 33645838370 scopus 로고    scopus 로고
    • The oxidative modification hypothesis of atherosclerosis: The comparison of atherogenic effects on oxidized LDL and remnant lipoproteins in plasma
    • K. Nakajima, T. Nakano, and A. Tanaka The oxidative modification hypothesis of atherosclerosis: The comparison of atherogenic effects on oxidized LDL and remnant lipoproteins in plasma Clin Chim Acta 367 2006 36 47
    • (2006) Clin Chim Acta , vol.367 , pp. 36-47
    • Nakajima, K.1    Nakano, T.2    Tanaka, A.3
  • 75
    • 0027745291 scopus 로고
    • Cholesterol in remnant-like lipoproteins in human serum using monoclonal anti apo B-100 and anti apo A-I immunoaffinity mixed gels
    • K. Nakajima, T. Saito, A. Tamura, M. Suzuki, T. Nakano, and M. Adachi et al. Cholesterol in remnant-like lipoproteins in human serum using monoclonal anti apo B-100 and anti apo A-I immunoaffinity mixed gels Clin Chim Acta 223 1993 53 71
    • (1993) Clin Chim Acta , vol.223 , pp. 53-71
    • Nakajima, K.1    Saito, T.2    Tamura, A.3    Suzuki, M.4    Nakano, T.5    Adachi, M.6
  • 76
    • 22544446477 scopus 로고    scopus 로고
    • Remnant lipoproteinemia is a risk factor for endothelial vasomotor dysfunction and coronary artery disease in metabolic syndrome
    • T. Nakamura, H. Takano, K. Umetani, K. Kawabata, J.E. Obata, and Y. Kitta et al. Remnant lipoproteinemia is a risk factor for endothelial vasomotor dysfunction and coronary artery disease in metabolic syndrome Atherosclerosis 181 2005 321 327
    • (2005) Atherosclerosis , vol.181 , pp. 321-327
    • Nakamura, T.1    Takano, H.2    Umetani, K.3    Kawabata, K.4    Obata, J.E.5    Kitta, Y.6
  • 77
    • 81255125373 scopus 로고    scopus 로고
    • Effects of the CETP inhibitor evacetrapib administered as monotherapy or in combination with statins on HDL and LDL cholesterol: A randomized controlled trial
    • S.J. Nicholls, H.B. Brewer, J.J. Kastelein, K.A. Krueger, M.D. Wang, and M. Shao et al. Effects of the CETP inhibitor evacetrapib administered as monotherapy or in combination with statins on HDL and LDL cholesterol: A randomized controlled trial JAMA 306 2011 2099 2109
    • (2011) JAMA , vol.306 , pp. 2099-2109
    • Nicholls, S.J.1    Brewer, H.B.2    Kastelein, J.J.3    Krueger, K.A.4    Wang, M.D.5    Shao, M.6
  • 78
    • 34447511196 scopus 로고    scopus 로고
    • Nonfasting triglycerides and risk of myocardial infarction, ischemic heart disease, and death in men and women
    • B.G. Nordestgaard, M. Benn, P. Schnohr, and A. Tybjaerg-Hansen Nonfasting triglycerides and risk of myocardial infarction, ischemic heart disease, and death in men and women JAMA 298 2007 299 308
    • (2007) JAMA , vol.298 , pp. 299-308
    • Nordestgaard, B.G.1    Benn, M.2    Schnohr, P.3    Tybjaerg-Hansen, A.4
  • 80
    • 79955583131 scopus 로고    scopus 로고
    • Clinical relevance of non-fasting and postprandial hypertriglyceridemia and remnant cholesterol
    • B.G. Nordestgaard, and J.J. Freiberg Clinical relevance of non-fasting and postprandial hypertriglyceridemia and remnant cholesterol Curr Vasc Pharmacol 9 2011 281 286
    • (2011) Curr Vasc Pharmacol , vol.9 , pp. 281-286
    • Nordestgaard, B.G.1    Freiberg, J.J.2
  • 82
    • 0023677501 scopus 로고
    • Reduced atherogenesis in cholesterol-fed diabetic rabbits. Giant lipoproteins do not enter the arterial wall
    • B.G. Nordestgaard, S. Stender, and K. Kjeldsen Reduced atherogenesis in cholesterol-fed diabetic rabbits. Giant lipoproteins do not enter the arterial wall Arteriosclerosis 8 1988 421 428
    • (1988) Arteriosclerosis , vol.8 , pp. 421-428
    • Nordestgaard, B.G.1    Stender, S.2    Kjeldsen, K.3
  • 83
    • 0026499897 scopus 로고
    • Influx in vivo of low density, intermediate density, and very low density lipoproteins into aortic intimas of genetically hyperlipidemic rabbits. Roles of plasma concentrations, extent of aortic lesion, and lipoprotein particle size as determinants
    • B.G. Nordestgaard, A. Tybjaerg-Hansen, and B. Lewis Influx in vivo of low density, intermediate density, and very low density lipoproteins into aortic intimas of genetically hyperlipidemic rabbits. Roles of plasma concentrations, extent of aortic lesion, and lipoprotein particle size as determinants Arterioscler Thromb 12 1992 6 18
    • (1992) Arterioscler Thromb , vol.12 , pp. 6-18
    • Nordestgaard, B.G.1    Tybjaerg-Hansen, A.2    Lewis, B.3
  • 84
    • 0028903142 scopus 로고
    • Selective retention of VLDL, IDL, and LDL in the arterial intima of genetically hyperlipidemic rabbits in vivo. Molecular size as a determinant of fractional loss from the intima-inner media
    • B.G. Nordestgaard, R. Wootton, and B. Lewis Selective retention of VLDL, IDL, and LDL in the arterial intima of genetically hyperlipidemic rabbits in vivo. Molecular size as a determinant of fractional loss from the intima-inner media Arterioscler Thromb Vasc Biol 15 1995 534 542
    • (1995) Arterioscler Thromb Vasc Biol , vol.15 , pp. 534-542
    • Nordestgaard, B.G.1    Wootton, R.2    Lewis, B.3
  • 85
    • 0024216203 scopus 로고
    • Large lipoproteins are excluded from the arterial wall in diabetic cholesterol-fed rabbits
    • B.G. Nordestgaard, and D.B. Zilversmit Large lipoproteins are excluded from the arterial wall in diabetic cholesterol-fed rabbits J Lipid Res 29 1988 1491 1500
    • (1988) J Lipid Res , vol.29 , pp. 1491-1500
    • Nordestgaard, B.G.1    Zilversmit, D.B.2
  • 86
    • 3042785737 scopus 로고    scopus 로고
    • Postprandial increase in plasma concentrations of remnant-like particles: An independent risk factor for restenosis after percutaneous coronary intervention
    • K. Oi, H. Shimokawa, Y. Hirakawa, H. Tashiro, R. Nakaike, and T. Kozai et al. Postprandial increase in plasma concentrations of remnant-like particles: An independent risk factor for restenosis after percutaneous coronary intervention J Cardiovasc Pharmacol 44 2004 66 73
    • (2004) J Cardiovasc Pharmacol , vol.44 , pp. 66-73
    • Oi, K.1    Shimokawa, H.2    Hirakawa, Y.3    Tashiro, H.4    Nakaike, R.5    Kozai, T.6
  • 87
  • 88
    • 77949485460 scopus 로고    scopus 로고
    • Mipomersen, an apolipoprotein B synthesis inhibitor, for lowering of LDL cholesterol concentrations in patients with homozygous familial hypercholesterolaemia: A randomised, double-blind, placebo-controlled trial
    • F.J. Raal, R.D. Santos, D.J. Blom, A.D. Marais, M.J. Charng, and W.C. Cromwell et al. Mipomersen, an apolipoprotein B synthesis inhibitor, for lowering of LDL cholesterol concentrations in patients with homozygous familial hypercholesterolaemia: A randomised, double-blind, placebo-controlled trial Lancet 375 2010 998 1006
    • (2010) Lancet , vol.375 , pp. 998-1006
    • Raal, F.J.1    Santos, R.D.2    Blom, D.J.3    Marais, A.D.4    Charng, M.J.5    Cromwell, W.C.6
  • 89
    • 84910137476 scopus 로고    scopus 로고
    • Recent advances in physiological lipoprotein metabolism
    • I. Ramasamy Recent advances in physiological lipoprotein metabolism Clin Chem Lab Med 12 2013 1 33
    • (2013) Clin Chem Lab Med , vol.12 , pp. 1-33
    • Ramasamy, I.1
  • 90
    • 0028172762 scopus 로고
    • Triglyceride-rich lipoproteins isolated by selected-affinity anti-apolipoprotein B immunosorption from human atherosclerotic plaque
    • J.H. Rapp, A. Lespine, R.L. Hamilton, N. Colyvas, A.H. Chaumeton, and J. Tweedie-Hardman et al. Triglyceride-rich lipoproteins isolated by selected-affinity anti-apolipoprotein B immunosorption from human atherosclerotic plaque Arterioscler Thromb 14 1994 1767 1774
    • (1994) Arterioscler Thromb , vol.14 , pp. 1767-1774
    • Rapp, J.H.1    Lespine, A.2    Hamilton, R.L.3    Colyvas, N.4    Chaumeton, A.H.5    Tweedie-Hardman, J.6
  • 91
    • 84866070612 scopus 로고    scopus 로고
    • Association between omega-3 fatty acid supplementation and risk of major cardiovascular disease events: A systematic review and meta-analysis
    • E.C. Rizos, E.E. Ntzani, E. Bika, M.S. Kostapanos, and M.S. Elisaf Association between omega-3 fatty acid supplementation and risk of major cardiovascular disease events: A systematic review and meta-analysis JAMA 308 2012 1024 1033
    • (2012) JAMA , vol.308 , pp. 1024-1033
    • Rizos, E.C.1    Ntzani, E.E.2    Bika, E.3    Kostapanos, M.S.4    Elisaf, M.S.5
  • 92
    • 85048354213 scopus 로고    scopus 로고
    • Combination lipid therapy in type 2 diabetes
    • F.M. Sacks, V.J. Carey, and J.C. Fruchart Combination lipid therapy in type 2 diabetes N Engl J Med 363 2010 692 694
    • (2010) N Engl J Med , vol.363 , pp. 692-694
    • Sacks, F.M.1    Carey, V.J.2    Fruchart, J.C.3
  • 93
    • 0032007349 scopus 로고    scopus 로고
    • Remnant-like particle cholesterol is a major risk factor for myocardial infarction in vasospastic angina with nearly normal coronary artery
    • K. Sakata, N. Miho, M. Shirotani, H. Yoshida, Y. Takada, and A. Takada Remnant-like particle cholesterol is a major risk factor for myocardial infarction in vasospastic angina with nearly normal coronary artery Atherosclerosis 136 1998 225 231
    • (1998) Atherosclerosis , vol.136 , pp. 225-231
    • Sakata, K.1    Miho, N.2    Shirotani, M.3    Yoshida, H.4    Takada, Y.5    Takada, A.6
  • 94
    • 0037465510 scopus 로고    scopus 로고
    • Role of risk factors in the modulation of tissue factor activity and blood thrombogenicity
    • A. Sambola, J. Osende, J. Hathcock, M. Degen, Y. Nemerson, and V. Fuster et al. Role of risk factors in the modulation of tissue factor activity and blood thrombogenicity Circulation 107 2003 973 977
    • (2003) Circulation , vol.107 , pp. 973-977
    • Sambola, A.1    Osende, J.2    Hathcock, J.3    Degen, M.4    Nemerson, Y.5    Fuster, V.6
  • 96
    • 0025797421 scopus 로고
    • Quantitative studies of transfer in vivo of low density, Sf 12-60, and Sf 60-400 lipoproteins between plasma and arterial intima in humans
    • M. Shaikh, R. Wootton, B.G. Nordestgaard, P. Baskerville, J.S. Lumley, and A.E. La Ville et al. Quantitative studies of transfer in vivo of low density, Sf 12-60, and Sf 60-400 lipoproteins between plasma and arterial intima in humans Arterioscler Thromb 11 1991 569 577
    • (1991) Arterioscler Thromb , vol.11 , pp. 569-577
    • Shaikh, M.1    Wootton, R.2    Nordestgaard, B.G.3    Baskerville, P.4    Lumley, J.S.5    La Ville, A.E.6
  • 97
    • 0033852044 scopus 로고    scopus 로고
    • Remnant-like particle cholesterol levels in Korean patients with coronary artery disease and non-insulin dependent diabetes mellitus
    • J. Song, H. Park, S.H. Hong, H.K. Lee, Y.B. Park, and J.Q. Kim Remnant-like particle cholesterol levels in Korean patients with coronary artery disease and non-insulin dependent diabetes mellitus Clin Chem Lab Med 38 2000 427 432
    • (2000) Clin Chem Lab Med , vol.38 , pp. 427-432
    • Song, J.1    Park, H.2    Hong, S.H.3    Lee, H.K.4    Park, Y.B.5    Kim, J.Q.6
  • 98
    • 53149112407 scopus 로고    scopus 로고
    • Association of fasting and nonfasting serum triglycerides with cardiovascular disease and the role of remnant-like lipoproteins and small dense LDL
    • A.F. Stalenhoef, and J. de Graaf Association of fasting and nonfasting serum triglycerides with cardiovascular disease and the role of remnant-like lipoproteins and small dense LDL Curr Opin Lipidol 19 2008 355 361
    • (2008) Curr Opin Lipidol , vol.19 , pp. 355-361
    • Stalenhoef, A.F.1    De Graaf, J.2
  • 99
    • 20244385536 scopus 로고    scopus 로고
    • Association of plasma triglyceride-rich lipoprotein remnants with coronary atherosclerosis in cases of sudden cardiac death
    • S. Takeichi, N. Yukawa, Y. Nakajima, M. Osawa, T. Saito, and Y. Seto et al. Association of plasma triglyceride-rich lipoprotein remnants with coronary atherosclerosis in cases of sudden cardiac death Atherosclerosis 142 1999 309 315
    • (1999) Atherosclerosis , vol.142 , pp. 309-315
    • Takeichi, S.1    Yukawa, N.2    Nakajima, Y.3    Osawa, M.4    Saito, T.5    Seto, Y.6
  • 101
    • 33847010885 scopus 로고    scopus 로고
    • Triglyceride-rich lipoproteins prime aortic endothelium for an enhanced inflammatory response to tumor necrosis factor-alpha
    • H.J. Ting, J.P. Stice, U.Y. Schaff, D.Y. Hui, J.C. Rutledge, and A.A. Knowlton et al. Triglyceride-rich lipoproteins prime aortic endothelium for an enhanced inflammatory response to tumor necrosis factor-alpha Circ Res 100 2007 381 390
    • (2007) Circ Res , vol.100 , pp. 381-390
    • Ting, H.J.1    Stice, J.P.2    Schaff, U.Y.3    Hui, D.Y.4    Rutledge, J.C.5    Knowlton, A.A.6
  • 102
    • 79551479646 scopus 로고    scopus 로고
    • TRIB1 and GCKR polymorphisms, lipid levels, and risk of ischemic heart disease in the general population
    • A. Varbo, M. Benn, A. Tybjaerg-Hansen, P. Grande, and B.G. Nordestgaard TRIB1 and GCKR polymorphisms, lipid levels, and risk of ischemic heart disease in the general population Arterioscler Thromb Vasc Biol 31 2011 451 457
    • (2011) Arterioscler Thromb Vasc Biol , vol.31 , pp. 451-457
    • Varbo, A.1    Benn, M.2    Tybjaerg-Hansen, A.3    Grande, P.4    Nordestgaard, B.G.5
  • 104
    • 84884284181 scopus 로고    scopus 로고
    • Elevated remnant cholesterol causes both low-grade inflammation and ischemic heart disease, while elevated low-density lipoprotein cholesterol causes ischemic heart disease without inflammation
    • A. Varbo, M. Benn, A. Tybjaerg-Hansen, and B.G. Nordestgaard Elevated remnant cholesterol causes both low-grade inflammation and ischemic heart disease, while elevated low-density lipoprotein cholesterol causes ischemic heart disease without inflammation Circulation 128 2013 1298 1309
    • (2013) Circulation , vol.128 , pp. 1298-1309
    • Varbo, A.1    Benn, M.2    Tybjaerg-Hansen, A.3    Nordestgaard, B.G.4
  • 106
    • 64749100482 scopus 로고    scopus 로고
    • Triglyceride-rich lipoprotein lipolysis releases neutral and oxidized FFAs that induce endothelial cell inflammation
    • L. Wang, R. Gill, T.L. Pedersen, L.J. Higgins, J.W. Newman, and J.C. Rutledge Triglyceride-rich lipoprotein lipolysis releases neutral and oxidized FFAs that induce endothelial cell inflammation J Lipid Res 50 2009 204 213
    • (2009) J Lipid Res , vol.50 , pp. 204-213
    • Wang, L.1    Gill, R.2    Pedersen, T.L.3    Higgins, L.J.4    Newman, J.W.5    Rutledge, J.C.6
  • 107
    • 38649125868 scopus 로고    scopus 로고
    • Newly identified loci that influence lipid concentrations and risk of coronary artery disease
    • C.J. Willer, S. Sanna, A.U. Jackson, A. Scuteri, L.L. Bonnycastle, and R. Clarke et al. Newly identified loci that influence lipid concentrations and risk of coronary artery disease Nat Genet 40 2008 161 169
    • (2008) Nat Genet , vol.40 , pp. 161-169
    • Willer, C.J.1    Sanna, S.2    Jackson, A.U.3    Scuteri, A.4    Bonnycastle, L.L.5    Clarke, R.6
  • 108
    • 34247471569 scopus 로고    scopus 로고
    • Hypertriglyceridemia: Its etiology, effects and treatment
    • G. Yuan, K.Z. Al-Shali, and R.A. Hegele Hypertriglyceridemia: Its etiology, effects and treatment CMAJ 176 2007 1113 1120
    • (2007) CMAJ , vol.176 , pp. 1113-1120
    • Yuan, G.1    Al-Shali, K.Z.2    Hegele, R.A.3
  • 109
    • 34548166870 scopus 로고    scopus 로고
    • Remnant-like lipoprotein particles impair endothelial function: Direct and indirect effects on nitric oxide synthase
    • X.Y. Zheng, and L. Liu Remnant-like lipoprotein particles impair endothelial function: Direct and indirect effects on nitric oxide synthase J Lipid Res 48 2007 1673 1680
    • (2007) J Lipid Res , vol.48 , pp. 1673-1680
    • Zheng, X.Y.1    Liu, L.2
  • 110
    • 0018649439 scopus 로고
    • Atherogenesis: A postprandial phenomenon
    • D.B. Zilversmit Atherogenesis: A postprandial phenomenon Circulation 60 1979 473 485
    • (1979) Circulation , vol.60 , pp. 473-485
    • Zilversmit, D.B.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.