메뉴 건너뛰기




Volumn 61, Issue 4, 2013, Pages 440-446

The current state of niacin in cardiovascular disease prevention: A systematic review and meta-regression

Author keywords

cardiovascular disease; HDL cholesterol; lipids; niacin

Indexed keywords

CLOFIBRATE; COLESTIPOL; COLESTYRAMINE; EZETIMIBE; GEMFIBROZIL; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; NICOTINIC ACID; PLACEBO; SIMVASTATIN;

EID: 84872679028     PISSN: 07351097     EISSN: 15583597     Source Type: Journal    
DOI: 10.1016/j.jacc.2012.10.030     Document Type: Article
Times cited : (162)

References (50)
  • 1
    • 0037126526 scopus 로고    scopus 로고
    • Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) Final Report
    • Adult Treatment Panel III
    • Adult Treatment Panel III Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) Final Report Circulation 106 2002 3143 3421
    • (2002) Circulation , vol.106 , pp. 3143-3421
  • 2
    • 4544275379 scopus 로고    scopus 로고
    • Implications of recent clinical trials for the National Cholesterol Education Program Adult Treatment Panel III Guidelines
    • S.M. Grundy, J.I. Cleeman, C.N.B. Merz Implications of recent clinical trials for the National Cholesterol Education Program Adult Treatment Panel III Guidelines J Am Coll Cardiol 44 2004 720 732
    • (2004) J Am Coll Cardiol , vol.44 , pp. 720-732
    • Grundy, S.M.1    Cleeman, J.I.2    Merz, C.N.B.3
  • 3
    • 81855224663 scopus 로고    scopus 로고
    • AHA/ACCF secondary prevention and risk reduction therapy for patients with coronary and other atherosclerotic vascular disease: 2011 update: A guideline from the American Heart Association and American College of Cardiology Foundation endorsed by the World Heart Federation and the Preventive Cardiovascular Nurses Association
    • S.C. Smith, E.J. Benjamin, R.O. Bonow AHA/ACCF secondary prevention and risk reduction therapy for patients with coronary and other atherosclerotic vascular disease: 2011 update: a guideline from the American Heart Association and American College of Cardiology Foundation endorsed by the World Heart Federation and the Preventive Cardiovascular Nurses Association J Am Coll Cardiol 58 2011 2432 2446
    • (2011) J Am Coll Cardiol , vol.58 , pp. 2432-2446
    • Smith, S.C.1    Benjamin, E.J.2    Bonow, R.O.3
  • 4
    • 26244432388 scopus 로고    scopus 로고
    • Efficacy and safety of cholesterol-lowering treatment: Prospective meta-analysis of data from 90,056 participants in 14 randomised trials of statins
    • C. Baigent, A. Keech, P.M. Kearney Efficacy and safety of cholesterol-lowering treatment: prospective meta-analysis of data from 90,056 participants in 14 randomised trials of statins Lancet 366 2005 1267 1278
    • (2005) Lancet , vol.366 , pp. 1267-1278
    • Baigent, C.1    Keech, A.2    Kearney, P.M.3
  • 5
    • 78449281377 scopus 로고    scopus 로고
    • Efficacy and safety of more intensive lowering of LDL cholesterol: A meta-analysis of data from 170,000 participants in 26 randomised trials
    • C. Baigent, L. Blackwell, J. Emberson Efficacy and safety of more intensive lowering of LDL cholesterol: a meta-analysis of data from 170,000 participants in 26 randomised trials Lancet 376 2010 1670 1681
    • (2010) Lancet , vol.376 , pp. 1670-1681
    • Baigent, C.1    Blackwell, L.2    Emberson, J.3
  • 6
    • 33746355566 scopus 로고    scopus 로고
    • Meta-analysis of cardiovascular outcomes trials comparing intensive versus moderate statin therapy
    • C.P. Cannon, B.A. Steinberg, S.A. Murphy, J.L. Mega, E. Braunwald Meta-analysis of cardiovascular outcomes trials comparing intensive versus moderate statin therapy J Am Coll Cardiol 48 2006 438 445
    • (2006) J Am Coll Cardiol , vol.48 , pp. 438-445
    • Cannon, C.P.1    Steinberg, B.A.2    Murphy, S.A.3    Mega, J.L.4    Braunwald, E.5
  • 7
    • 11144355354 scopus 로고    scopus 로고
    • Intensive versus moderate lipid lowering with statins after acute coronary syndromes
    • C. Cannon, E. Braunwald, C. McCabe Intensive versus moderate lipid lowering with statins after acute coronary syndromes N Engl J Med 350 2004 1495 1504
    • (2004) N Engl J Med , vol.350 , pp. 1495-1504
    • Cannon, C.1    Braunwald, E.2    McCabe, C.3
  • 8
    • 15944410609 scopus 로고    scopus 로고
    • Intensive lipid lowering with atorvastatin in patients with stable coronary disease
    • J.C. LaRosa, S.M. Grundy, D.D. Waters Intensive lipid lowering with atorvastatin in patients with stable coronary disease N Engl J Med 352 2005 1425 1435
    • (2005) N Engl J Med , vol.352 , pp. 1425-1435
    • Larosa, J.C.1    Grundy, S.M.2    Waters, D.D.3
  • 9
    • 4544243333 scopus 로고    scopus 로고
    • Early intensive vs a delayed conservative simvastatin strategy in patients with acute coronary syndromes: Phase Z of the A to Z trial
    • J. de Lemos, M. Blazing, S. Wiviott Early intensive vs a delayed conservative simvastatin strategy in patients with acute coronary syndromes: phase Z of the A to Z trial JAMA 292 2004 1307 1316
    • (2004) JAMA , vol.292 , pp. 1307-1316
    • De Lemos, J.1    Blazing, M.2    Wiviott, S.3
  • 10
    • 27744603499 scopus 로고    scopus 로고
    • High-dose atorvastatin vs usual-dose simvastatin for secondary prevention after myocardial infarction
    • T. Pedersen, O. Faergeman, J. Kastelein High-dose atorvastatin vs usual-dose simvastatin for secondary prevention after myocardial infarction JAMA 294 2005 2437 2445
    • (2005) JAMA , vol.294 , pp. 2437-2445
    • Pedersen, T.1    Faergeman, O.2    Kastelein, J.3
  • 11
    • 78449267756 scopus 로고    scopus 로고
    • Intensive lowering of LDL cholesterol with 80 mg versus 20 mg simvastatin daily in 12,064 survivors of myocardial infarction: A double-blind randomised trial
    • J. Armitage, L. Bowman, K. Wallendszus Intensive lowering of LDL cholesterol with 80 mg versus 20 mg simvastatin daily in 12,064 survivors of myocardial infarction: a double-blind randomised trial Lancet 376 2010 1658 1669
    • (2010) Lancet , vol.376 , pp. 1658-1669
    • Armitage, J.1    Bowman, L.2    Wallendszus, K.3
  • 12
    • 0033751381 scopus 로고    scopus 로고
    • Mechanism of action of niacin on lipoprotein metabolism
    • V.S. Kamanna, M.L. Kashyap Mechanism of action of niacin on lipoprotein metabolism Curr Atheroscler Rep 2 2000 36 46
    • (2000) Curr Atheroscler Rep , vol.2 , pp. 36-46
    • Kamanna, V.S.1    Kashyap, M.L.2
  • 13
    • 36448978498 scopus 로고    scopus 로고
    • Nicotinic acid (niacin) receptor agonists: Will they be useful therapeutic agents?
    • V.S. Kamanna, M.L. Kashyap Nicotinic acid (niacin) receptor agonists: will they be useful therapeutic agents? Am J Cardiol 100 2007 S53 S61
    • (2007) Am J Cardiol , vol.100
    • Kamanna, V.S.1    Kashyap, M.L.2
  • 15
    • 0016630250 scopus 로고
    • Clofibrate and niacin in coronary heart disease
    • Coronary Drug Project Research Group
    • Coronary Drug Project Research Group Clofibrate and niacin in coronary heart disease JAMA 231 1975 360 381
    • (1975) JAMA , vol.231 , pp. 360-381
  • 16
    • 0035969564 scopus 로고    scopus 로고
    • Simvastatin and niacin, antioxidant vitamins, or the combination for the prevention of coronary disease
    • B. Brown, X. Zhao, A. Chait Simvastatin and niacin, antioxidant vitamins, or the combination for the prevention of coronary disease N Engl J Med 345 2001 1583 1592
    • (2001) N Engl J Med , vol.345 , pp. 1583-1592
    • Brown, B.1    Zhao, X.2    Chait, A.3
  • 17
    • 10044281651 scopus 로고    scopus 로고
    • Arterial Biology for the Investigation of the Treatment Effects of Reducing Cholesterol (ARBITER) 2: A double-blind, placebo-controlled study of extended-release niacin on atherosclerosis progression in secondary prevention patients treated with statins
    • A.J. Taylor, L.E. Sullenberger, H.J. Lee, J.K. Lee, K.A. Grace Arterial Biology for the Investigation of the Treatment Effects of Reducing Cholesterol (ARBITER) 2: a double-blind, placebo-controlled study of extended-release niacin on atherosclerosis progression in secondary prevention patients treated with statins Circulation 110 2004 3512 3517
    • (2004) Circulation , vol.110 , pp. 3512-3517
    • Taylor, A.J.1    Sullenberger, L.E.2    Lee, H.J.3    Lee, J.K.4    Grace, K.A.5
  • 18
    • 33751217682 scopus 로고    scopus 로고
    • The effect of 24 months of combination statin and extended-release niacin on carotid intima-media thickness: ARBITER 3
    • A.J. Taylor, H.J. Lee, L.E. Sullenberger The effect of 24 months of combination statin and extended-release niacin on carotid intima-media thickness: ARBITER 3 Curr Med Res Opin 22 2006 2243 2250
    • (2006) Curr Med Res Opin , vol.22 , pp. 2243-2250
    • Taylor, A.J.1    Lee, H.J.2    Sullenberger, L.E.3
  • 19
    • 72049129430 scopus 로고    scopus 로고
    • Extended-release niacin or ezetimibe and carotid intima-media thickness
    • A. Taylor, T. Villines, E. Stanek Extended-release niacin or ezetimibe and carotid intima-media thickness N Engl J Med 361 2009 2113 2122
    • (2009) N Engl J Med , vol.361 , pp. 2113-2122
    • Taylor, A.1    Villines, T.2    Stanek, E.3
  • 20
    • 77953121328 scopus 로고    scopus 로고
    • The ARBITER 6-HALTS Trial (Arterial Biology for the Investigation of the Treatment Effects of Reducing Cholesterol 6-HDL and LDL Treatment Strategies in Atherosclerosis): Final results and the impact of medication adherence, dose, and treatment duration
    • T.C. Villines, E.J. Stanek, P.J. Devine The ARBITER 6-HALTS Trial (Arterial Biology for the Investigation of the Treatment Effects of Reducing Cholesterol 6-HDL and LDL Treatment Strategies in Atherosclerosis): final results and the impact of medication adherence, dose, and treatment duration J Am Coll Cardiol 55 2010 2721 2726
    • (2010) J Am Coll Cardiol , vol.55 , pp. 2721-2726
    • Villines, T.C.1    Stanek, E.J.2    Devine, P.J.3
  • 21
    • 70350516769 scopus 로고    scopus 로고
    • Effects of high-dose modified-release nicotinic acid on atherosclerosis and vascular function: A randomized, placebo-controlled, magnetic resonance imaging study
    • J.M.S. Lee, M.D. Robson, L.-M. Yu Effects of high-dose modified-release nicotinic acid on atherosclerosis and vascular function: a randomized, placebo-controlled, magnetic resonance imaging study J Am Coll Cardiol 54 2009 1787 1794
    • (2009) J Am Coll Cardiol , vol.54 , pp. 1787-1794
    • Lee, J.M.S.1    Robson, M.D.2    Yu, L.-M.3
  • 22
    • 84855171302 scopus 로고    scopus 로고
    • Niacin in patients with low HDL cholesterol levels receiving intensive statin therapy
    • W.E. Boden, J.L. Probstfield, T. Anderson Niacin in patients with low HDL cholesterol levels receiving intensive statin therapy N Engl J Med 365 2011 2255 2267
    • (2011) N Engl J Med , vol.365 , pp. 2255-2267
    • Boden, W.E.1    Probstfield, J.L.2    Anderson, T.3
  • 23
    • 77952397461 scopus 로고    scopus 로고
    • Meta-analysis of the effect of nicotinic acid alone or in combination on cardiovascular events and atherosclerosis
    • E. Bruckert, J. Labreuche, P. Amarenco Meta-analysis of the effect of nicotinic acid alone or in combination on cardiovascular events and atherosclerosis Atherosclerosis 210 2010 353 361
    • (2010) Atherosclerosis , vol.210 , pp. 353-361
    • Bruckert, E.1    Labreuche, J.2    Amarenco, P.3
  • 24
    • 77951928738 scopus 로고    scopus 로고
    • Effect of niacin therapy on cardiovascular outcomes in patients with coronary artery disease
    • J.K. Duggal, M. Singh, N. Attri Effect of niacin therapy on cardiovascular outcomes in patients with coronary artery disease J Cardiovasc Pharmacol Ther 15 2010 158 166
    • (2010) J Cardiovasc Pharmacol Ther , vol.15 , pp. 158-166
    • Duggal, J.K.1    Singh, M.2    Attri, N.3
  • 25
    • 0025183769 scopus 로고
    • Regression of coronary artery disease as a result of intensive lipid-lowering therapy in men with high levels of apolipoprotein B
    • G. Brown, J. Albers, L. Fisher Regression of coronary artery disease as a result of intensive lipid-lowering therapy in men with high levels of apolipoprotein B N Engl J Med 323 1990 1289 1298
    • (1990) N Engl J Med , vol.323 , pp. 1289-1298
    • Brown, G.1    Albers, J.2    Fisher, L.3
  • 26
    • 41949131921 scopus 로고    scopus 로고
    • Lipid-altering efficacy and safety of ezetimibe/simvastatin coadministered with extended-release niacin in patients with type IIa or type IIb hyperlipidemia
    • J.R. Guyton, B.G. Brown, S. Fazio, A. Polis, J.E. Tomassini, A.M. Tershakovec Lipid-altering efficacy and safety of ezetimibe/simvastatin coadministered with extended-release niacin in patients with type IIa or type IIb hyperlipidemia J Am Coll Cardiol 51 2008 1564 1572
    • (2008) J Am Coll Cardiol , vol.51 , pp. 1564-1572
    • Guyton, J.R.1    Brown, B.G.2    Fazio, S.3    Polis, A.4    Tomassini, J.E.5    Tershakovec, A.M.6
  • 27
    • 0029914622 scopus 로고    scopus 로고
    • Assessing the quality of reports of randomized clinical trials: Is blinding necessary?
    • A.R. Jadad, R.A. Moore, D. Carroll Assessing the quality of reports of randomized clinical trials: is blinding necessary? Control Clin Trials 17 1996 1 12
    • (1996) Control Clin Trials , vol.17 , pp. 1-12
    • Jadad, A.R.1    Moore, R.A.2    Carroll, D.3
  • 28
    • 19944426989 scopus 로고    scopus 로고
    • A randomized trial of a strategy for increasing high-density lipoprotein cholesterol levels: Effects on progression of coronary heart disease and clinical events
    • E.J. Whitney, R.A. Krasuski, B.E. Personius, J.E. Michalek, A.M. Maranian, M.W. Kolasa A randomized trial of a strategy for increasing high-density lipoprotein cholesterol levels: effects on progression of coronary heart disease and clinical events Ann Intern Med 142 2005 95 104
    • (2005) Ann Intern Med , vol.142 , pp. 95-104
    • Whitney, E.J.1    Krasuski, R.A.2    Personius, B.E.3    Michalek, J.E.4    Maranian, A.M.5    Kolasa, M.W.6
  • 29
    • 84948007950 scopus 로고
    • Beneficial effects of combined colestipol-niacin therapy on coronary atherosclerosis and coronary venous bypass grafts
    • D.H. Blankenhorn, S.A. Nessim, R.L. Johnson, M.E. Sanmarco, S.P. Azen, L. Cashin-Hemphill Beneficial effects of combined colestipol-niacin therapy on coronary atherosclerosis and coronary venous bypass grafts JAMA 257 1987 3233 3240
    • (1987) JAMA , vol.257 , pp. 3233-3240
    • Blankenhorn, D.H.1    Nessim, S.A.2    Johnson, R.L.3    Sanmarco, M.E.4    Azen, S.P.5    Cashin-Hemphill, L.6
  • 30
    • 0023910325 scopus 로고
    • Reduction of mortality in the Stockholm Ischaemic Heart Disease Secondary Prevention Study by combined treatment with clofibrate and nicotinic acid
    • L.A. Carlson, G. Rosenhamer Reduction of mortality in the Stockholm Ischaemic Heart Disease Secondary Prevention Study by combined treatment with clofibrate and nicotinic acid Acta Med Scand 223 1988 405 418
    • (1988) Acta Med Scand , vol.223 , pp. 405-418
    • Carlson, L.A.1    Rosenhamer, G.2
  • 31
    • 0025685469 scopus 로고
    • Regression of coronary atherosclerosis during treatment of familial hypercholesterolemia with combined drug regimens
    • J.P. Kane, M.J. Malloy, T.A. Ports, N.R. Phillips, J.C. Diehl, R.J. Havel Regression of coronary atherosclerosis during treatment of familial hypercholesterolemia with combined drug regimens JAMA 264 1990 3007 3012
    • (1990) JAMA , vol.264 , pp. 3007-3012
    • Kane, J.P.1    Malloy, M.J.2    Ports, T.A.3    Phillips, N.R.4    Diehl, J.C.5    Havel, R.J.6
  • 32
    • 0033596281 scopus 로고    scopus 로고
    • Effect of statins on risk of coronary disease: A meta-analysis of randomized controlled trials
    • J.C. Larosa, J. He, S. Vupputuri, M.S. Headings Effect of statins on risk of coronary disease: a meta-analysis of randomized controlled trials JAMA 282 1999 2340 2346
    • (1999) JAMA , vol.282 , pp. 2340-2346
    • Larosa, J.C.1    He, J.2    Vupputuri, S.3    Headings, M.S.4
  • 33
    • 78751640788 scopus 로고    scopus 로고
    • Meta-analysis: Statin therapy does not alter the association between low levels of high-density lipoprotein cholesterol and increased cardiovascular risk
    • H. Jafri, A.A. Alsheikh-Ali, R.H. Karas Meta-analysis: statin therapy does not alter the association between low levels of high-density lipoprotein cholesterol and increased cardiovascular risk Ann Intern Med 153 2010 800 808
    • (2010) Ann Intern Med , vol.153 , pp. 800-808
    • Jafri, H.1    Alsheikh-Ali, A.A.2    Karas, R.H.3
  • 34
    • 0017384270 scopus 로고
    • High density lipoprotein as a protective factor against coronary heart disease the Framingham Study
    • T. Gordon, W. Castelli, M. Hjortland, W. Kannel, T. Daber High density lipoprotein as a protective factor against coronary heart disease The Framingham Study Am J Med 62 1977 707 714
    • (1977) Am J Med , vol.62 , pp. 707-714
    • Gordon, T.1    Castelli, W.2    Hjortland, M.3    Kannel, W.4    Daber, T.5
  • 35
    • 0018949549 scopus 로고
    • Prevalence of coronary heart disease in the Framingham Offspring Study: Role of lipoprotein cholesterols
    • P. Wilson, R. Garrison, W. Castelli, M. Feinleib, P. McNamara, W. Kannel Prevalence of coronary heart disease in the Framingham Offspring Study: role of lipoprotein cholesterols Am J Cardiol 46 1980 649 654
    • (1980) Am J Cardiol , vol.46 , pp. 649-654
    • Wilson, P.1    Garrison, R.2    Castelli, W.3    Feinleib, M.4    McNamara, P.5    Kannel, W.6
  • 36
    • 0023029454 scopus 로고
    • Incidence of coronary heart disease and lipoprotein cholesterol levels the Framingham Study
    • W. Castelli, R. Garrison, P. Wilson, R. Abbott, S. Kalousdian, W. Kannel Incidence of coronary heart disease and lipoprotein cholesterol levels The Framingham Study JAMA 256 1986 2835 2838
    • (1986) JAMA , vol.256 , pp. 2835-2838
    • Castelli, W.1    Garrison, R.2    Wilson, P.3    Abbott, R.4    Kalousdian, S.5    Kannel, W.6
  • 37
    • 0024501678 scopus 로고
    • High-density lipoprotein cholesterol and cardiovascular disease Four prospective American studies
    • D.J. Gordon, J.L. Probstfield, R.J. Garrison High-density lipoprotein cholesterol and cardiovascular disease Four prospective American studies Circulation 79 1989 8 15
    • (1989) Circulation , vol.79 , pp. 8-15
    • Gordon, D.J.1    Probstfield, J.L.2    Garrison, R.J.3
  • 38
    • 33748038025 scopus 로고    scopus 로고
    • Effects of extended-release niacin on lipoprotein particle size, distribution, and inflammatory markers in patients with coronary artery disease
    • J.T. Kuvin, D.M. Dave, K.A. Sliney Effects of extended-release niacin on lipoprotein particle size, distribution, and inflammatory markers in patients with coronary artery disease Am J Cardiol 98 2006 743 745
    • (2006) Am J Cardiol , vol.98 , pp. 743-745
    • Kuvin, J.T.1    Dave, D.M.2    Sliney, K.A.3
  • 39
    • 77049084050 scopus 로고    scopus 로고
    • Anti-inflammatory effects of nicotinic acid in adipocytes demonstrated by suppression of fractalkine, RANTES, and MCP-1 and upregulation of adiponectin
    • J.E. Digby, E. McNeill, O.J. Dyar, V. Lam, D.R. Greaves, R.P. Choudhury Anti-inflammatory effects of nicotinic acid in adipocytes demonstrated by suppression of fractalkine, RANTES, and MCP-1 and upregulation of adiponectin Atherosclerosis 209 2010 89 95
    • (2010) Atherosclerosis , vol.209 , pp. 89-95
    • Digby, J.E.1    McNeill, E.2    Dyar, O.J.3    Lam, V.4    Greaves, D.R.5    Choudhury, R.P.6
  • 40
    • 67349267972 scopus 로고    scopus 로고
    • Effects of extended-release niacin on lipid profile and adipocyte biology in patients with impaired glucose tolerance
    • A. Linke, M. Sonnabend, M. Fasshauer Effects of extended-release niacin on lipid profile and adipocyte biology in patients with impaired glucose tolerance Atherosclerosis 205 2009 207 213
    • (2009) Atherosclerosis , vol.205 , pp. 207-213
    • Linke, A.1    Sonnabend, M.2    Fasshauer, M.3
  • 41
    • 70350516769 scopus 로고    scopus 로고
    • Effects of high-dose modified-release nicotinic acid on atherosclerosis and vascular function: A randomized, placebo-controlled, magnetic resonance imaging study
    • J.M.S. Lee, M.D. Robson, L.-M. Yu Effects of high-dose modified-release nicotinic acid on atherosclerosis and vascular function: a randomized, placebo-controlled, magnetic resonance imaging study J Am Coll Cardiol 54 2009 1787 1794
    • (2009) J Am Coll Cardiol , vol.54 , pp. 1787-1794
    • Lee, J.M.S.1    Robson, M.D.2    Yu, L.-M.3
  • 42
    • 77951483195 scopus 로고    scopus 로고
    • Evidence that niacin inhibits acute vascular inflammation and improves endothelial dysfunction independent of changes in plasma lipids
    • B.J. Wu, L. Yan, F. Charlton, P. Witting, P.J. Barter, K.-A. Rye Evidence that niacin inhibits acute vascular inflammation and improves endothelial dysfunction independent of changes in plasma lipids Arterioscler Thromb Vasc Biol 30 2010 968 975
    • (2010) Arterioscler Thromb Vasc Biol , vol.30 , pp. 968-975
    • Wu, B.J.1    Yan, L.2    Charlton, F.3    Witting, P.4    Barter, P.J.5    Rye, K.-A.6
  • 43
    • 79952240405 scopus 로고    scopus 로고
    • Nicotinic acid inhibits progression of atherosclerosis in mice through its receptor GPR109a expressed by immune cells
    • M. Lukasova, C. Malaval, A. Gille, J. Kero Nicotinic acid inhibits progression of atherosclerosis in mice through its receptor GPR109a expressed by immune cells J Clin Invest 121 2011 1163 1173
    • (2011) J Clin Invest , vol.121 , pp. 1163-1173
    • Lukasova, M.1    Malaval, C.2    Gille, A.3    Kero, J.4
  • 44
    • 79954995814 scopus 로고    scopus 로고
    • Nicotinic acid has anti-atherogenic and anti-inflammatory properties on advanced atherosclerotic lesions independent of its lipid-modifying capabilities
    • E. Holzhäuser, C. Albrecht, Q. Zhou Nicotinic acid has anti-atherogenic and anti-inflammatory properties on advanced atherosclerotic lesions independent of its lipid-modifying capabilities J Cardiovasc Pharmacol 57 2011 447 454
    • (2011) J Cardiovasc Pharmacol , vol.57 , pp. 447-454
    • Holzhäuser, E.1    Albrecht, C.2    Zhou, Q.3
  • 47
    • 84864845456 scopus 로고    scopus 로고
    • Plasma HDL cholesterol and risk of myocardial infarction: A mendelian randomisation study
    • B.F. Voight, G.M. Peloso, M. Orho-Melander Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study Lancet 6736 2012 1 9
    • (2012) Lancet , vol.6736 , pp. 1-9
    • Voight, B.F.1    Peloso, G.M.2    Orho-Melander, M.3
  • 48
    • 41149151640 scopus 로고    scopus 로고
    • The safety of niacin in the US Food and Drug Administration adverse event reporting database
    • A.A. Alsheikh-Ali, R.H. Karas The safety of niacin in the US Food and Drug Administration adverse event reporting database Am J Cardiol 101 2008 9B 13B
    • (2008) Am J Cardiol , vol.101
    • Alsheikh-Ali, A.A.1    Karas, R.H.2
  • 49
    • 33846508107 scopus 로고    scopus 로고
    • Safety of lovastatin/extended release niacin compared with lovastatin alone, atorvastatin alone, pravastatin alone, and simvastatin alone (from the United States Food and Drug Administration adverse event reporting system)
    • A.A. Alsheikh-Ali, R.H. Karas Safety of lovastatin/extended release niacin compared with lovastatin alone, atorvastatin alone, pravastatin alone, and simvastatin alone (from the United States Food and Drug Administration adverse event reporting system) Am J Cardiol 99 2007 379 381
    • (2007) Am J Cardiol , vol.99 , pp. 379-381
    • Alsheikh-Ali, A.A.1    Karas, R.H.2
  • 50
    • 40649097282 scopus 로고    scopus 로고
    • Comparison of the efficacy and safety of a combination tablet of niacin extended-release and simvastatin with simvastatin 80 mg monotherapy: The SEACOAST II (high-dose) study
    • C.M. Ballantyne, M.H. Davidson, J.M. McKenney, L.H. Keller, D.R. Bajorunas, R.H. Karas Comparison of the efficacy and safety of a combination tablet of niacin extended-release and simvastatin with simvastatin 80 mg monotherapy: the SEACOAST II (high-dose) study J Clin Lipidol 2 2008 79 90
    • (2008) J Clin Lipidol , vol.2 , pp. 79-90
    • Ballantyne, C.M.1    Davidson, M.H.2    McKenney, J.M.3    Keller, L.H.4    Bajorunas, D.R.5    Karas, R.H.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.