Proton-coupled electron transfer and adduct configuration are important for C4a-hydroperoxyflavin formation and stabilization in a flavoenzyme

Journal of the American Chemical Society

Volumn 136, Issue 1, 2014, Pages 241-253

  Wongnate, Thanyaporn ^a   Surawatanawong, Panida ^a   Visitsatthawong, Surawit ^a   Sucharitakul, Jeerus ^b   Scrutton, Nigel S ^c   Chaiyen, Pimchai ^a  

^a Mahidol University ^*  (Thailand)

^b CHULALONGKORN UNIVERSITY   (Thailand)

^c UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

COMPUTATIONAL RESULTS; DIOXYGEN ACTIVATION; KINETIC ISOTOPE EFFECTS; POSITIVELY CHARGED; PROTON-COUPLED ELECTRON TRANSFER; SINGLE ELECTRON TRANSFER; SITE DIRECTED MUTAGENESIS; UNIMOLECULAR REACTIONS;

CATALYSIS; ISOTOPES; KINETICS; PROTON TRANSFER; REACTION KINETICS;

ELECTRON TRANSITIONS;

C4A HYDROPEROXYFLAVIN; FLAVOPROTEIN; OXYGEN; PYRANOSE 2 OXIDASE; QUERCETIN; SUPEROXIDE; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; DENSITY FUNCTIONAL THEORY; ENTHALPY; PH; PROTON TRANSPORT; SITE DIRECTED MUTAGENESIS; STATIC ELECTRICITY; TEMPERATURE;

CARBOHYDRATE DEHYDROGENASES; CATALYTIC DOMAIN; COMPUTER SIMULATION; ELECTRON-TRANSFERRING FLAVOPROTEINS; ENZYME STABILITY; FLAVINS; MODELS, MOLECULAR; OXIDATION-REDUCTION; OXYGEN; PROTONS; QUANTUM THEORY; TEMPERATURE;

EID: 84892170130     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja4088055     Document Type: Article

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