Hydrogen peroxide elimination from C4a-hydroperoxyflavin in a flavoprotein oxidase occurs through a single proton transfer from flavin N5 to a peroxide leaving group

Journal of Biological Chemistry

Volumn 286, Issue 19, 2011, Pages 16900-16909

  Sucharitakul, Jeerus ^a   Wongnate, Thanyaporn ^b   Chaiyen, Pimchai ^b  

^a CHULALONGKORN UNIVERSITY   (Thailand)

^b MAHIDOL UNIVERSITY   (Thailand)

Author keywords

[No Author keywords available]

Indexed keywords

ELECTRON ACCEPTOR; FLAVIN-DEPENDENT; INTRAMOLECULAR HYDROGEN BRIDGES; INVENTORY ANALYSIS; KINETIC ISOTOPE EFFECTS; LEAVING GROUPS; MONOOXYGENASES; OXYGEN ATOM; PYRANOSE; SOLVENT KINETIC ISOTOPE EFFECTS; STOPPED FLOW EXPERIMENTS; TRANSFER PROCESS; TRANSIENT KINETICS; TRANSITION STATE;

CARRIER MOBILITY; DEUTERIUM; ENZYMES; EXPERIMENTS; HYDROGEN; HYDROGEN PEROXIDE; KINETICS; OXYGEN; PROTON TRANSFER; REACTION INTERMEDIATES; REACTION KINETICS; SUGARS;

OXIDATION;

C4A HYDROPEROXYFLAVIN; FLAVIN N5; FLAVOPROTEIN; HYDROGEN PEROXIDE; QUERCETIN; UNCLASSIFIED DRUG; UNSPECIFIC MONOOXYGENASE;

ARTICLE; CHEMICAL ANALYSIS; CHEMICAL STRUCTURE; ELIMINATION REACTION; ENZYME KINETICS; HYDROGEN BOND; OXYGENATION; PRIORITY JOURNAL; PROTON TRANSPORT; SPECTROSCOPY;

CATALYSIS; FLAVINS; FLAVOPROTEINS; HYDROGEN PEROXIDE; KINETICS; MODELS, CHEMICAL; OXIDOREDUCTASES; OXYGEN; PEROXIDES; PROTONS; SPECTROPHOTOMETRY, ULTRAVIOLET; SUBSTRATE SPECIFICITY; TEMPERATURE; TIME FACTORS;

EID: 79955750085     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.222976     Document Type: Article

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