Structural characterization of mutations at the oxygen activation site in monomeric sarcosine oxidase

Biochemistry

Volumn 49, Issue 17, 2010, Pages 3631-3639

  Jorns, Marilyn Schuman ^a   Chen, Zhi Wei ^b   Mathews, F Scott ^b  

^a DREXEL UNIVERSITY COLLEGE OF MEDICINE   (United States)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APPARENT KINETICS; BINDING CAVITY; BULK SOLVENTS; OXYGEN ACTIVATIONS; OXYGEN REACTIVITY; OXYGEN REDUCTION; PROTON-RELAY SYSTEMS; REACTION INTERMEDIATE; SARCOSINE; SARCOSINE OXIDASE; SIDE CHAINS; STRUCTURAL CHARACTERIZATION; STRUCTURAL WATER; WILD TYPES;

CONFORMATIONS; ELECTROLYTIC REDUCTION; POSITIVE IONS; REACTION INTERMEDIATES; REACTION RATES;

OXYGEN;

ARGININE; FLAVOPROTEIN; LYSINE; METHIONINE; MONOMERIC SARCOSINE OXIDASE; OXYGEN; PROTON; SARCOSINE OXIDASE; STRUCTURAL WATER WAT1; UNCLASSIFIED DRUG; WATER;

ARTICLE; BINDING AFFINITY; CATALYSIS; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME KINETICS; ENZYME STABILITY; ENZYME STRUCTURE; MOLECULE; MUTATIONAL ANALYSIS; OXIDATION; OXIDATION REDUCTION REACTION; OXYGEN AFFINITY; PRIORITY JOURNAL; PROTEIN CONFORMATION; SOLUTION AND SOLUBILITY; WILD TYPE;

AMINO ACID SUBSTITUTION; BINDING SITES; CATALYSIS; CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; FLAVINS; KINETICS; LYSINE; MODELS, MOLECULAR; MOLECULAR STRUCTURE; MUTAGENESIS, SITE-DIRECTED; MUTATION; OXIDATION-REDUCTION; OXYGEN; PROTEIN CONFORMATION; SARCOSINE; SARCOSINE OXIDASE;

EID: 77951698123     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi100160j     Document Type: Article

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