Engagement of two distinct binding domains on CCL17 is required for signaling through CCR4 and establishment of localized inflammatory conditions in the lung

PLoS ONE

Volumn 8, Issue 12, 2013, Pages

  Santulli Marotto, Sandra ^a,b   Boakye, Ken ^a   Lacy, Eilyn ^a   Wu, Sheng Jiun ^a   Luongo, Jennifer ^a   Kavalkovich, Karl ^a   Coelho, Ana ^b   Hogaboam, Cory M ^b   Ryan, Mary ^a  

^a JANSSEN RESEARCH AND DEVELOPMENT   (Belgium)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; B202 ANTIBODY; B225 ANTIBODY; BETA ARRESTIN; CHEMOKINE RECEPTOR CCR4; MACROPHAGE DERIVED CHEMOKINE; THYMUS AND ACTIVATION REGULATED CHEMOKINE; UNCLASSIFIED DRUG; CCL17 PROTEIN, MOUSE; CCR4 PROTEIN, MOUSE; NEUTRALIZING ANTIBODY; PROTEIN BINDING;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN BINDING; ARTICLE; ASTHMA; BINDING AFFINITY; BINDING SITE; CALCIUM MOBILIZATION; CONTROLLED STUDY; FEMALE; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; ANIMAL; CHEMISTRY; IMMUNOLOGY; LUNG; METABOLISM; PATHOLOGY; PROTEIN TERTIARY STRUCTURE;

ANIMALS; ANTIBODIES, NEUTRALIZING; CHEMOKINE CCL17; CHEMOKINE CCL22; FEMALE; LUNG; MICE; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, CCR4; SIGNAL TRANSDUCTION;

EID: 84891937678     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0081465     Document Type: Article

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