메뉴 건너뛰기




Volumn 44, Issue 1, 2014, Pages 129-136

Serum response factor induces epithelial to mesenchymal transition with resistance to sorafenib in hepatocellular carcinoma

Author keywords

Carcinoma; Chemoresistance; Hepatocellular; Serum response factor

Indexed keywords

SERUM RESPONSE FACTOR; SORAFENIB; TRANSCRIPTION FACTOR SNAIL; UVOMORULIN;

EID: 84891930752     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo.2013.2154     Document Type: Article
Times cited : (22)

References (42)
  • 1
    • 84860287080 scopus 로고    scopus 로고
    • Epidemiology of viral hepatitis and hepatocellular carcinoma
    • El-Serag HB: Epidemiology of viral hepatitis and hepatocellular carcinoma. Gastroenterology 142: 1264-1273, 2012.
    • (2012) Gastroenterology , vol.142 , pp. 1264-1273
    • El-Serag, H.B.1
  • 3
    • 33745547361 scopus 로고    scopus 로고
    • New therapies for hepatocellular carcinoma
    • Avila MA, Berasain C, Sangro B and Prieto J: New therapies for hepatocellular carcinoma. Oncogene 25: 3866-3884, 2006.
    • (2006) Oncogene , vol.25 , pp. 3866-3884
    • Avila, M.A.1    Berasain, C.2    Sangro, B.3    Prieto, J.4
  • 4
    • 63049123066 scopus 로고    scopus 로고
    • Transitions between epithelial and mesenchymal states: Acquisition of malignant and stem cell traits
    • Polyak K and Weinberg RA: Transitions between epithelial and mesenchymal states: acquisition of malignant and stem cell traits. Nat Rev Cancer 9: 265-273, 2009.
    • (2009) Nat Rev Cancer , vol.9 , pp. 265-273
    • Polyak, K.1    Weinberg, R.A.2
  • 5
    • 67650999875 scopus 로고    scopus 로고
    • The basics of epithelial-mesenchymal transition
    • Kalluri R and Weinberg RA: The basics of epithelial-mesenchymal transition. J Clin Invest 119: 1420-1428, 2009.
    • (2009) J Clin Invest , vol.119 , pp. 1420-1428
    • Kalluri, R.1    Weinberg, R.A.2
  • 6
    • 69549131213 scopus 로고    scopus 로고
    • Residual breast cancers after conventional therapy display mesenchymal as well as tumor-initiating features
    • Creighton CJ, Li X, Landis M, et al: Residual breast cancers after conventional therapy display mesenchymal as well as tumor-initiating features. Proc Natl Acad Sci USA 106: 13820-13825, 2009.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 13820-13825
    • Creighton, C.J.1    Li, X.2    Landis, M.3
  • 7
    • 77956178360 scopus 로고    scopus 로고
    • EMT, cancer stem cells and drug resistance: An emerging axis of evil in the war on cancer
    • Singh A and Settleman J: EMT, cancer stem cells and drug resistance: an emerging axis of evil in the war on cancer. Oncogene 29: 4741-4751, 2010.
    • (2010) Oncogene , vol.29 , pp. 4741-4751
    • Singh, A.1    Settleman, J.2
  • 8
    • 70349859809 scopus 로고    scopus 로고
    • Snail and slug mediate radioresistance and chemoresistance by antagonizing P53-mediated apoptosis and acquiring a stem-like phenotype in ovarian cancer cells
    • Kurrey NK, Jalgaonkar SP, Joglekar AV, et al: Snail and slug mediate radioresistance and chemoresistance by antagonizing P53-mediated apoptosis and acquiring a stem-like phenotype in ovarian cancer cells. Stem Cells 27: 2059-2068, 2009.
    • (2009) Stem Cells , vol.27 , pp. 2059-2068
    • Kurrey, N.K.1    Jalgaonkar, S.P.2    Joglekar, A.V.3
  • 9
    • 65549141305 scopus 로고    scopus 로고
    • Acquisition of epithelial-mesenchymal transition phenotype of gemcitabine-resistant pancreatic cancer cells is linked with activation of the notch signaling pathway
    • Wang Z, Li Y, Kong D, et al: Acquisition of epithelial-mesenchymal transition phenotype of gemcitabine-resistant pancreatic cancer cells is linked with activation of the notch signaling pathway. Cancer Res 69: 2400-2407, 2009.
    • (2009) Cancer Res , vol.69 , pp. 2400-2407
    • Wang, Z.1    Li, Y.2    Kong, D.3
  • 10
    • 34249289041 scopus 로고    scopus 로고
    • Snail, ZEB and bHLH factors in tumour progression: An alliance against the epithelial phenotype?
    • Peinado H, Olmeda D and Cano A: Snail, ZEB and bHLH factors in tumour progression: an alliance against the epithelial phenotype? Nat Rev Cancer 7: 415-428, 2007.
    • (2007) Nat Rev Cancer , vol.7 , pp. 415-428
    • Peinado, H.1    Olmeda, D.2    Cano, A.3
  • 11
    • 0022486539 scopus 로고
    • Identification of a protein-binding site that mediates transcriptional response of the c-fos gene to serum factors
    • Treisman R: Identification of a protein-binding site that mediates transcriptional response of the c-fos gene to serum factors. Cell 46: 567-574, 1986.
    • (1986) Cell , vol.46 , pp. 567-574
    • Treisman, R.1
  • 12
    • 0023411439 scopus 로고
    • Identification and purification of a polypeptide that binds to the c-fos serum response element
    • Treisman R: Identification and purification of a polypeptide that binds to the c-fos serum response element. EMBO J 6: 2711-2717, 1987.
    • (1987) EMBO J , vol.6 , pp. 2711-2717
    • Treisman, R.1
  • 13
    • 0028934434 scopus 로고
    • The MADS-box family of transcription factors
    • Shore P and Sharrocks AD: The MADS-box family of transcription factors. Eur J Biochem 229: 1-3, 1995.
    • (1995) Eur J Biochem , vol.229 , pp. 1-3
    • Shore, P.1    Sharrocks, A.D.2
  • 14
    • 77952665466 scopus 로고    scopus 로고
    • Serum response factor: Look into the gut
    • Modak C and Chai J: Serum response factor: look into the gut. World J Gastroenterol 16: 2195-2201, 2010.
    • (2010) World J Gastroenterol , vol.16 , pp. 2195-2201
    • Modak, C.1    Chai, J.2
  • 15
    • 77956260813 scopus 로고    scopus 로고
    • Role of serum response factor in the pathogenesis of disease
    • Miano JM: Role of serum response factor in the pathogenesis of disease. Lab Invest 90: 1274-1284, 2010.
    • (2010) Lab Invest , vol.90 , pp. 1274-1284
    • Miano, J.M.1
  • 16
    • 0037119356 scopus 로고    scopus 로고
    • High activity of serum response factor in the mesenchymal transition of epithelial tumor cells is regulated by RhoA signaling
    • Psichari E, Balmain A, Plows D, Zoumpourlis V and Pintzas A: High activity of serum response factor in the mesenchymal transition of epithelial tumor cells is regulated by RhoA signaling. J Biol Chem 277: 29490-29495, 2002.
    • (2002) J Biol Chem , vol.277 , pp. 29490-29495
    • Psichari, E.1    Balmain, A.2    Plows, D.3    Zoumpourlis, V.4    Pintzas, A.5
  • 17
    • 38449102928 scopus 로고    scopus 로고
    • Expression of the serum response factor in hepatocellular carcinoma: Implications for epithelial-mesenchymal transition
    • Park MY, Kim KR, Park HS, et al: Expression of the serum response factor in hepatocellular carcinoma: Implications for epithelial-mesenchymal transition. Int J Oncol 31: 1309-1315, 2007.
    • (2007) Int J Oncol , vol.31 , pp. 1309-1315
    • Park, M.Y.1    Kim, K.R.2    Park, H.S.3
  • 18
    • 77956521605 scopus 로고    scopus 로고
    • The role of serum response factor in hepatocellular carcinoma: Implications for disease progression
    • Kwon CY, Kim KR, Choi HN, et al: The role of serum response factor in hepatocellular carcinoma: Implications for disease progression. Int J Oncol 37: 837-844, 2010.
    • (2010) Int J Oncol , vol.37 , pp. 837-844
    • Kwon, C.Y.1    Kim, K.R.2    Choi, H.N.3
  • 19
    • 61449495071 scopus 로고    scopus 로고
    • Serum response factor enhances liver metastasis of colorectal carcinoma via alteration of the E-cadherin/β-catenin complex
    • Choi HN, Kim KR, Lee JH, et al: Serum response factor enhances liver metastasis of colorectal carcinoma via alteration of the E-cadherin/β- catenin complex. Oncol Rep 21: 57-63, 2009.
    • (2009) Oncol Rep , vol.21 , pp. 57-63
    • Choi, H.N.1    Kim, K.R.2    Lee, J.H.3
  • 20
    • 77951025471 scopus 로고    scopus 로고
    • Serum response factor depletion affects the proliferation of the hepatocellular carcinoma cells HepG2 and JHH6
    • Farra R, Dapas B, Pozzato G, et al: Serum response factor depletion affects the proliferation of the hepatocellular carcinoma cells HepG2 and JHH6. Biochimie 92: 455-463, 2010.
    • (2010) Biochimie , vol.92 , pp. 455-463
    • Farra, R.1    Dapas, B.2    Pozzato, G.3
  • 21
    • 33749238553 scopus 로고    scopus 로고
    • Discovery and development of sorafenib: A multikinase inhibitor for treating cancer
    • Wilhelm S, Carter C, Lynch M, et al: Discovery and development of sorafenib: a multikinase inhibitor for treating cancer. Nat Rev Drug Discov 5: 835-844, 2006.
    • (2006) Nat Rev Drug Discov , vol.5 , pp. 835-844
    • Wilhelm, S.1    Carter, C.2    Lynch, M.3
  • 22
    • 55749088393 scopus 로고    scopus 로고
    • Preclinical overview of sorafenib, a multikinase inhibitor that targets both Raf and VEGF and PDGF receptor tyrosine kinase signaling
    • Wilhelm SM, Adnane L, Newell P, Villanueva A, Llovet JM and Lynch M: Preclinical overview of sorafenib, a multikinase inhibitor that targets both Raf and VEGF and PDGF receptor tyrosine kinase signaling. Mol Cancer Ther 7: 3129-3140, 2008.
    • (2008) Mol Cancer Ther , vol.7 , pp. 3129-3140
    • Wilhelm, S.M.1    Adnane, L.2    Newell, P.3    Villanueva, A.4    Llovet, J.M.5    Lynch, M.6
  • 23
    • 61449175950 scopus 로고    scopus 로고
    • Sorafenib for the treatment of unresectable hepatocellular carcinoma
    • Kane RC, Farrell AT, Madabushi R, et al: Sorafenib for the treatment of unresectable hepatocellular carcinoma. Oncologist 14: 95-100, 2009.
    • (2009) Oncologist , vol.14 , pp. 95-100
    • Kane, R.C.1    Farrell, A.T.2    Madabushi, R.3
  • 25
    • 0037081848 scopus 로고    scopus 로고
    • A comprehensive karyotypic analysis on a newly established sarcomatoid hepatocellular carcinoma cell line SH-J1 by comparative genomic hybridization and chromosome painting
    • Kim DG, Park SY, Kim H, Chun YH, Moon WS and Park SH: A comprehensive karyotypic analysis on a newly established sarcomatoid hepatocellular carcinoma cell line SH-J1 by comparative genomic hybridization and chromosome painting. Cancer Genet Cytogenet 132: 120-124, 2002.
    • (2002) Cancer Genet Cytogenet , vol.132 , pp. 120-124
    • Kim, D.G.1    Park, S.Y.2    Kim, H.3    Chun, Y.H.4    Moon, W.S.5    Park, S.H.6
  • 26
    • 84861978789 scopus 로고    scopus 로고
    • Expression of K19 and K7 in dysplastic nodules and hepatocellular carcinoma
    • Bae JS, Choi HN, Noh SJ, et al: Expression of K19 and K7 in dysplastic nodules and hepatocellular carcinoma. Oncol Lett 4: 213-220, 2012.
    • (2012) Oncol Lett , vol.4 , pp. 213-220
    • Bae, J.S.1    Choi, H.N.2    Noh, S.J.3
  • 27
    • 38449095879 scopus 로고    scopus 로고
    • A peroxisome proliferator-activated receptor γ antagonist induces vimentin cleavage and inhibits invasion in high-grade hepatocellular carcinoma
    • Kim KR, Choi HN, Lee HJ, et al: A peroxisome proliferator-activated receptor γ antagonist induces vimentin cleavage and inhibits invasion in high-grade hepatocellular carcinoma. Oncol Rep 18: 825-832, 2007.
    • (2007) Oncol Rep , vol.18 , pp. 825-832
    • Kim, K.R.1    Choi, H.N.2    Lee, H.J.3
  • 28
    • 0033784843 scopus 로고    scopus 로고
    • The transcription factor Snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression
    • Cano A, Pérez-Moreno MA, Rodrigo I, et al: The transcription factor Snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression. Nat Cell Biol 2: 76-83, 2000.
    • (2000) Nat Cell Biol , vol.2 , pp. 76-83
    • Cano, A.1    Pérez-Moreno, M.A.2    Rodrigo, I.3
  • 29
    • 77951229724 scopus 로고    scopus 로고
    • Expression and prognostic significance of serum response factor in cholangiocarcinoma
    • Park SY, Jang KY, Kim YN, et al: Expression and prognostic significance of serum response factor in cholangiocarcinoma. Korean J Pathol 43: 517-522, 2009.
    • (2009) Korean J Pathol , vol.43 , pp. 517-522
    • Park, S.Y.1    Jang, K.Y.2    Kim, Y.N.3
  • 30
    • 80053494147 scopus 로고    scopus 로고
    • The role of serum response factor in hepatocellular carcinoma: An association with matrix metalloproteinase
    • Kim KR, Bae JS, Choi HN, et al: The role of serum response factor in hepatocellular carcinoma: An association with matrix metalloproteinase. Oncol Rep 26: 1567-1572, 2011.
    • (2011) Oncol Rep , vol.26 , pp. 1567-1572
    • Kim, K.R.1    Bae, J.S.2    Choi, H.N.3
  • 31
    • 84873949249 scopus 로고    scopus 로고
    • Role of sorafenib in the treatment of advanced hepatocellular carcinoma: An update
    • Gauthier A and Ho M: Role of sorafenib in the treatment of advanced hepatocellular carcinoma: an update. Hepatol Res 43: 147-154, 2013.
    • (2013) Hepatol Res , vol.43 , pp. 147-154
    • Gauthier, A.1    Ho, M.2
  • 32
    • 35148825636 scopus 로고    scopus 로고
    • Chemoresistance to paclitaxel induces epithelial-mesenchymal transition and enhances metastatic potential for epithelial ovarian carcinoma cells
    • Kajiyama H, Shibata K, Terauchi M, et al: Chemoresistance to paclitaxel induces epithelial-mesenchymal transition and enhances metastatic potential for epithelial ovarian carcinoma cells. Int J Oncol 31: 277-283, 2007.
    • (2007) Int J Oncol , vol.31 , pp. 277-283
    • Kajiyama, H.1    Shibata, K.2    Terauchi, M.3
  • 33
    • 33847327128 scopus 로고    scopus 로고
    • Chronic oxaliplatin resistance induces epithelial-to-mesenchymal transition in colorectal cancer cell lines
    • Yang AD, Fan F, Camp ER, et al: Chronic oxaliplatin resistance induces epithelial-to-mesenchymal transition in colorectal cancer cell lines. Clin Cancer Res 12: 4147-4153, 2006.
    • (2006) Clin Cancer Res , vol.12 , pp. 4147-4153
    • Yang, A.D.1    Fan, F.2    Camp, E.R.3
  • 34
    • 58049200145 scopus 로고    scopus 로고
    • Epithelial to mesenchymal transition derived from repeated exposure to gefitinib determines the sensitivity to EGFR inhibitors in A549, a non-small cell lung cancer cell line
    • Rho JK, Choi YJ, Lee JK, et al: Epithelial to mesenchymal transition derived from repeated exposure to gefitinib determines the sensitivity to EGFR inhibitors in A549, a non-small cell lung cancer cell line. Lung Cancer 63: 219-226, 2009.
    • (2009) Lung Cancer , vol.63 , pp. 219-226
    • Rho, J.K.1    Choi, Y.J.2    Lee, J.K.3
  • 35
    • 84871721735 scopus 로고    scopus 로고
    • Long-term exposure to sorafenib of liver cancer cells induces resistance with epithelial-to-mesenchymal transition, increased invasion and risk of rebound growth
    • Van Malenstein H, Dekervel J, Verslype C, et al: Long-term exposure to sorafenib of liver cancer cells induces resistance with epithelial-to- mesenchymal transition, increased invasion and risk of rebound growth. Cancer Lett 329: 74-83, 2013.
    • (2013) Cancer Lett , vol.329 , pp. 74-83
    • Van Malenstein, H.1    Dekervel, J.2    Verslype, C.3
  • 36
    • 84879074139 scopus 로고    scopus 로고
    • αB-crystallin complexes with 14-3-3ζ to induce epithelial-mesenchymal transition and resistance to sorafenib in hepatocellular carcinoma
    • Huang XY, Ke AW, Shi GM, et al: αB-crystallin complexes with 14-3-3ζ to induce epithelial-mesenchymal transition and resistance to sorafenib in hepatocellular carcinoma. Hepatology 57: 2235-2247, 2013.
    • (2013) Hepatology , vol.57 , pp. 2235-2247
    • Huang, X.Y.1    Ke, A.W.2    Shi, G.M.3
  • 37
    • 78751523982 scopus 로고    scopus 로고
    • Sorafenib inhibits the hepatocyte growth factor-mediated epithelial mesenchymal transition in hepatocellular carcinoma
    • Nagai T, Arao T, Furuta K, et al: Sorafenib inhibits the hepatocyte growth factor-mediated epithelial mesenchymal transition in hepatocellular carcinoma. Mol Cancer Ther 10: 169-177, 2011.
    • (2011) Mol Cancer Ther , vol.10 , pp. 169-177
    • Nagai, T.1    Arao, T.2    Furuta, K.3
  • 38
    • 79960297620 scopus 로고    scopus 로고
    • 388 enhances prostate cancer progression via extracellular signal-related kinase and serum response factor signaling
    • 388 enhances prostate cancer progression via extracellular signal-related kinase and serum response factor signaling. Clin Cancer Res 17: 4355-4366, 2011.
    • (2011) Clin Cancer Res , vol.17 , pp. 4355-4366
    • Yu, W.1    Feng, S.2    Dakhova, O.3
  • 39
    • 84876287828 scopus 로고    scopus 로고
    • Identification of transcription factors associated with castration-resistance: Is the serum responsive factor a potential therapeutic target?
    • Prencipe M, Madden SF, O'Neill A, et al: Identification of transcription factors associated with castration-resistance: is the serum responsive factor a potential therapeutic target? Prostate 73: 743-753, 2013.
    • (2013) Prostate , vol.73 , pp. 743-753
    • Prencipe, M.1    Madden, S.F.2    O'Neill, A.3
  • 40
    • 34548689625 scopus 로고    scopus 로고
    • Tumor recurrence after liver transplantation for hepatocellular carcinoma: Recurrence pathway and prognostic factors
    • Pérez-Saborido B, de los Galanes SJ, Menéu-Díaz JC, et al: Tumor recurrence after liver transplantation for hepatocellular carcinoma: recurrence pathway and prognostic factors. Transplant Proc 39: 2304-2307, 2007.
    • (2007) Transplant Proc , vol.39 , pp. 2304-2307
    • Pérez-Saborido, B.1    De Los Galanes, S.J.2    Menéu-Díaz, J.C.3
  • 41
    • 61849140657 scopus 로고    scopus 로고
    • Myocardin-related transcription factors and SRF are required for cytoskeletal dynamics and experimental metastasis
    • Medjkane S, Perez-Sanchez C, Gaggioli C, Sahai E and Treisman R: Myocardin-related transcription factors and SRF are required for cytoskeletal dynamics and experimental metastasis. Nat Cell Biol 11: 257-268, 2009.
    • (2009) Nat Cell Biol , vol.11 , pp. 257-268
    • Medjkane, S.1    Perez-Sanchez, C.2    Gaggioli, C.3    Sahai, E.4    Treisman, R.5
  • 42
    • 70450285075 scopus 로고    scopus 로고
    • MicroRNA-122 inhibits tumorigenic properties of hepatocellular carcinoma cells and sensitizes these cells to sorafenib
    • Bai S, Nasser MW, Wang B, et al: MicroRNA-122 inhibits tumorigenic properties of hepatocellular carcinoma cells and sensitizes these cells to sorafenib. J Biol Chem 284: 32015-32027, 2009.
    • (2009) J Biol Chem , vol.284 , pp. 32015-32027
    • Bai, S.1    Nasser, M.W.2    Wang, B.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.