Propofol protects against focal cerebral ischemia via inhibition of microglia-mediated proinflammatory cytokines in a rat model of experimental stroke

PLoS ONE

Volumn 8, Issue 12, 2013, Pages

  Zhou, Rong ^a   Yang, Zailiang ^b,c   Tang, Xurong ^a   Tan, Yan ^c   Wu, Xiaofeng ^c   Liu, Feng ^a  

^a CHONGQING MEDICAL UNIVERSITY   (China)

^b BEIJING INSTITUTE OF MICROBIOLOGY AND EPIDEMIOLOGY   (China)

^c THIRD MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

C REACTIVE PROTEIN; CD68 ANTIGEN; COMPLEMENT COMPONENT C5A RECEPTOR; INTERLEUKIN 1BETA; INTERLEUKIN 6; MESSENGER RNA; PROPOFOL; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN INFARCTION SIZE; BRAIN PERFUSION; CEREBROVASCULAR ACCIDENT; CONTROLLED STUDY; CYTOKINE PRODUCTION; EXPERIMENTAL STROKE; IMMUNOHISTOCHEMISTRY; MALE; MICROGLIA; MIDDLE CEREBRAL ARTERY OCCLUSION; NEUROPROTECTION; NONHUMAN; PROTEIN EXPRESSION; RAT; REAL TIME POLYMERASE CHAIN REACTION; ROTAROD TEST; WESTERN BLOTTING;

ANIMALS; BIOLOGICAL MARKERS; BRAIN ISCHEMIA; CYTOKINES; DISEASE MODELS, ANIMAL; GENE EXPRESSION; INFARCTION, MIDDLE CEREBRAL ARTERY; INFLAMMATION MEDIATORS; MALE; MICROGLIA; NEUROPROTECTIVE AGENTS; PROPOFOL; RATS; STROKE;

EID: 84891920974     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0082729     Document Type: Article

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