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Volumn 31, Issue 1, 2014, Pages 287-297

Suppression of the invasive potential of highly malignant tumor cells by KIOM-C, a novel herbal medicine, via inhibition of NF-κB activation and MMP-9 expression

Author keywords

Herbal medicine; Matrix metalloproteinases; Metastasis; NF B

Indexed keywords

GELATINASE B; HERBACEOUS AGENT; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; KIOM-C; UNCLASSIFIED DRUG;

EID: 84891920245     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.2013.2822     Document Type: Article
Times cited : (15)

References (40)
  • 1
    • 0026027556 scopus 로고
    • Cancer metastasis and angiogenesis: An imbalance of positive and negative regulation
    • Liotta LA, Steeg PS and Stetler-Stevenson WG: Cancer metastasis and angiogenesis: an imbalance of positive and negative regulation. Cell 64: 327-336, 1991.
    • (1991) Cell , vol.64 , pp. 327-336
    • Liotta, L.A.1    Steeg, P.S.2    Stetler-Stevenson, W.G.3
  • 2
    • 33745260422 scopus 로고    scopus 로고
    • Metalloproteinases in tumor progression
    • In Spanish
    • Arvelo F and Cotte C: Metalloproteinases in tumor progression. Review. Invest Clin 47: 185-205, 2006 (In Spanish).
    • (2006) Review. Invest Clin , vol.47 , pp. 185-205
    • Arvelo, F.1    Cotte, C.2
  • 4
    • 0034176764 scopus 로고    scopus 로고
    • Matrix metalloproteinases: Multifunctional contributors to tumor progression
    • McCawley LJ and Matrisian LM: Matrix metalloproteinases: multifunctional contributors to tumor progression. Mol Med Today 6: 149-156, 2000.
    • (2000) Mol Med Today , vol.6 , pp. 149-156
    • McCawley, L.J.1    Matrisian, L.M.2
  • 5
    • 0041851264 scopus 로고    scopus 로고
    • Relationship between expression of matrix metalloproteinase (MMP-9) and tumor angiogenesis, cancer cell proliferation, invasion, and metastasis in invasive carcinoma of cervix
    • In Chinese
    • Jiang ZQ, Zhu FC, Qu JY, Zheng X and You CL: Relationship between expression of matrix metalloproteinase (MMP-9) and tumor angiogenesis, cancer cell proliferation, invasion, and metastasis in invasive carcinoma of cervix. Ai Zheng 22: 178-184, 2003 (In Chinese).
    • (2003) Ai Zheng , vol.22 , pp. 178-184
    • Jiang, Z.Q.1    Zhu, F.C.2    Qu, J.Y.3    Zheng, X.4    You, C.L.5
  • 6
    • 0033146396 scopus 로고    scopus 로고
    • Correlation between expression of matrix metalloproteinase-2 (MMP-2), and matrix metalloproteinase-9 (MMP-9) and angiogenesis in colorectal adenocarcinoma
    • Kim TS and Kim YB: Correlation between expression of matrix metalloproteinase-2 (MMP-2), and matrix metalloproteinase-9 (MMP-9) and angiogenesis in colorectal adenocarcinoma. J Korean Med Sci 14: 263-270, 1999.
    • (1999) J Korean Med Sci , vol.14 , pp. 263-270
    • Kim, T.S.1    Kim, Y.B.2
  • 7
    • 0242658826 scopus 로고    scopus 로고
    • A novel antisense inhibitor of MMP-9 attenuates angiogenesis, human prostate cancer cell invasion and tumorigenicity
    • London CA, Sekhon HS, Arora V, Stein DA, Iversen PL and Devi GR: A novel antisense inhibitor of MMP-9 attenuates angiogenesis, human prostate cancer cell invasion and tumorigenicity. Cancer Gene Ther 10: 823-832, 2003.
    • (2003) Cancer Gene Ther , vol.10 , pp. 823-832
    • London, C.A.1    Sekhon, H.S.2    Arora, V.3    Stein, D.A.4    Iversen, P.L.5    Devi, G.R.6
  • 8
    • 2942718949 scopus 로고    scopus 로고
    • Inhibition of cathepsin B and MMP-9 gene expression in glioblastoma cell line via RNA interference reduces tumor cell invasion, tumor growth and angiogenesis
    • Lakka SS, Gondi CS, Yanamandra N, et al: Inhibition of cathepsin B and MMP-9 gene expression in glioblastoma cell line via RNA interference reduces tumor cell invasion, tumor growth and angiogenesis. Oncogene 23: 4681-4689, 2004.
    • (2004) Oncogene , vol.23 , pp. 4681-4689
    • Lakka, S.S.1    Gondi, C.S.2    Yanamandra, N.3
  • 9
    • 34248178375 scopus 로고    scopus 로고
    • Inhibition of angiogenesis and invasion by 3,3′-diindolylmethane is mediated by the nuclear factor-κB downstream target genes MMP-9 and uPA that regulated bioavailability of vascular endothelial growth factor in prostate cancer
    • Kong D, Li Y, Wang Z, Banerjee S and Sarkar FH: Inhibition of angiogenesis and invasion by 3,3′-diindolylmethane is mediated by the nuclear factor-κB downstream target genes MMP-9 and uPA that regulated bioavailability of vascular endothelial growth factor in prostate cancer. Cancer Res 67: 3310-3319, 2007.
    • (2007) Cancer Res , vol.67 , pp. 3310-3319
    • Kong, D.1    Li, Y.2    Wang, Z.3    Banerjee, S.4    Sarkar, F.H.5
  • 10
    • 34548279788 scopus 로고    scopus 로고
    • Molecular understanding and modern application of traditional medicines: Triumphs and trials
    • Corson TW and Crews CM: Molecular understanding and modern application of traditional medicines: triumphs and trials. Cell 130: 769-774, 2007.
    • (2007) Cell , vol.130 , pp. 769-774
    • Corson, T.W.1    Crews, C.M.2
  • 11
    • 14744297337 scopus 로고    scopus 로고
    • Combination effects of herbs in a multi-herbal formula: Expression of Juzen-taiho-to's immuno-modulatory activity on the intestinal immune system
    • Kiyohara H, Matsumoto T and Yamada H: Combination effects of herbs in a multi-herbal formula: expression of Juzen-taiho-to's immuno-modulatory activity on the intestinal immune system. Evid Based Complement Alternat Med 1: 83-91, 2004.
    • (2004) Evid Based Complement Alternat Med , vol.1 , pp. 83-91
    • Kiyohara, H.1    Matsumoto, T.2    Yamada, H.3
  • 12
    • 84877921514 scopus 로고    scopus 로고
    • Effects of the novel herbal medicine, KIOM-C, on the growth performance and immune status of porcine circovirus-associated disease (PCVAD) affected pigs
    • Chung TH, Kang TJ, Lee GS, et al: Effects of the novel herbal medicine, KIOM-C, on the growth performance and immune status of porcine circovirus-associated disease (PCVAD) affected pigs. J Med Plants Res 6: 4456-4466, 2012.
    • (2012) J Med Plants Res , vol.6 , pp. 4456-4466
    • Chung, T.H.1    Kang, T.J.2    Lee, G.S.3
  • 13
    • 84877090923 scopus 로고    scopus 로고
    • Immunomodulation and attenuation of lethal influenza A virus infection by oral administration with KIOM-C
    • Kim EH, Pascua PN, Song MS, et al: Immunomodulation and attenuation of lethal influenza A virus infection by oral administration with KIOM-C. Antiviral Res 98: 386-393, 2013.
    • (2013) Antiviral Res , vol.98 , pp. 386-393
    • Kim, E.H.1    Pascua, P.N.2    Song, M.S.3
  • 14
    • 0022469754 scopus 로고
    • Clonogenicity and experimental metastatic potential of spontaneous mouse mammary neoplasms
    • Price JE: Clonogenicity and experimental metastatic potential of spontaneous mouse mammary neoplasms. J Natl Cancer Inst 77: 529-535, 1986.
    • (1986) J Natl Cancer Inst , vol.77 , pp. 529-535
    • Price, J.E.1
  • 15
    • 66749136330 scopus 로고    scopus 로고
    • Suppression of NF-κB activity by NDRG2 expression attenuates the invasive potential of highly malignant tumor cells
    • Kim A, Kim MJ, Yang Y, Kim JW, Yeom YI and Lim JS: Suppression of NF-κB activity by NDRG2 expression attenuates the invasive potential of highly malignant tumor cells. Carcinogenesis 30: 927-936, 2009.
    • (2009) Carcinogenesis , vol.30 , pp. 927-936
    • Kim, A.1    Kim, M.J.2    Yang, Y.3    Kim, J.W.4    Yeom, Y.I.5    Lim, J.S.6
  • 16
    • 74249121743 scopus 로고    scopus 로고
    • Acacetin inhibits TPA-induced MMP-2 and u-PA expressions of human lung cancer cells through inactivating JNK signaling pathway and reducing binding activities of NF-κB and AP-1
    • Fong Y, Shen KH, Chiang TA and Shih YW: Acacetin inhibits TPA-induced MMP-2 and u-PA expressions of human lung cancer cells through inactivating JNK signaling pathway and reducing binding activities of NF-κB and AP-1. J Food Sci 75: 30-38, 2010.
    • (2010) J Food Sci , vol.75 , pp. 30-38
    • Fong, Y.1    Shen, K.H.2    Chiang, T.A.3    Shih, Y.W.4
  • 17
    • 0344845283 scopus 로고    scopus 로고
    • Induction of myofibroblast MMP-9 transcription in three-dimensional collagen I gel cultures: Regulation by NF-κB, AP-1 and Sp1
    • Takahra T, Smart DE, Oakley F and Mann DA: Induction of myofibroblast MMP-9 transcription in three-dimensional collagen I gel cultures: regulation by NF-κB, AP-1 and Sp1. Int J Biochem Cell Biol 36: 353-363, 2004.
    • (2004) Int J Biochem Cell Biol , vol.36 , pp. 353-363
    • Takahra, T.1    Smart, D.E.2    Oakley, F.3    Mann, D.A.4
  • 18
    • 0029680268 scopus 로고    scopus 로고
    • Metastatic inefficiency: Intravascular and intraperitoneal implantation of cancer cells
    • Weiss L: Metastatic inefficiency: intravascular and intraperitoneal implantation of cancer cells. Cancer Treat Res 82: 1-11, 1996.
    • (1996) Cancer Treat Res , vol.82 , pp. 1-11
    • Weiss, L.1
  • 19
    • 18844383164 scopus 로고    scopus 로고
    • The current role of chemotherapy in metastatic hormone-refractory prostate cancer
    • Petrylak DP: The current role of chemotherapy in metastatic hormone-refractory prostate cancer. Urology 65: 3-7, 2005.
    • (2005) Urology , vol.65 , pp. 3-7
    • Petrylak, D.P.1
  • 20
    • 22144497147 scopus 로고    scopus 로고
    • Chemotherapy in advanced non-small cell lung cancer
    • Evans T: Chemotherapy in advanced non-small cell lung cancer. Semin Respir Crit Care Med 26: 304-313, 2005.
    • (2005) Semin Respir Crit Care Med , vol.26 , pp. 304-313
    • Evans, T.1
  • 21
    • 84878788661 scopus 로고    scopus 로고
    • Elevated expression of both MDR1 and MMP-2 genes in metastasized lymph node of invasive ductal breast cancer
    • Lu LS, Chen L, Ding WX, Li K and Wu JJ: Elevated expression of both MDR1 and MMP-2 genes in metastasized lymph node of invasive ductal breast cancer. Eur Rev Med Pharmacol Sci 16: 2037-2043, 2012.
    • (2012) Eur Rev Med Pharmacol Sci , vol.16 , pp. 2037-2043
    • Lu, L.S.1    Chen, L.2    Ding, W.X.3    Li, K.4    Wu, J.J.5
  • 22
    • 33747159104 scopus 로고    scopus 로고
    • MMP-9 and MMP-2 gelatinases and TIMP-1 and TIMP-2 inhibitors in breast cancer: Correlations with prognostic factors
    • Jinga DC, Blidaru A, Condrea I, et al: MMP-9 and MMP-2 gelatinases and TIMP-1 and TIMP-2 inhibitors in breast cancer: correlations with prognostic factors. J Cell Mol Med 10: 499-510, 2006.
    • (2006) J Cell Mol Med , vol.10 , pp. 499-510
    • Jinga, D.C.1    Blidaru, A.2    Condrea, I.3
  • 23
    • 12244284240 scopus 로고    scopus 로고
    • MMP-2 protein in invasive breast cancer and the impact of MMP-2/TIMP-2 phenotype on overall survival
    • Nakopoulou L, Tsirmpa I, Alexandrou P, et al: MMP-2 protein in invasive breast cancer and the impact of MMP-2/TIMP-2 phenotype on overall survival. Breast Cancer Res Treat 77: 145-155, 2003.
    • (2003) Breast Cancer Res Treat , vol.77 , pp. 145-155
    • Nakopoulou, L.1    Tsirmpa, I.2    Alexandrou, P.3
  • 24
    • 33845366687 scopus 로고    scopus 로고
    • An Oriental herbal cocktail, Ka-Mi-Kae-Kyuk-Tang, exerts anticancer activities by targeting angiogenesis, apoptosis and metastasis
    • Lee HJ, Lee EO, Rhee YH, et al: An Oriental herbal cocktail, Ka-Mi-Kae-Kyuk-Tang, exerts anticancer activities by targeting angiogenesis, apoptosis and metastasis. Carcinogenesis 27: 2455-2463, 2006.
    • (2006) Carcinogenesis , vol.27 , pp. 2455-2463
    • Lee, H.J.1    Lee, E.O.2    Rhee, Y.H.3
  • 25
    • 77549086838 scopus 로고    scopus 로고
    • Antimetastatic effects of Terminalia catappa L. on oral cancer via a down-regulation of metastasis-associated proteases
    • Yang SF, Chen MK, Hsieh YS, et al: Antimetastatic effects of Terminalia catappa L. on oral cancer via a down-regulation of metastasis-associated proteases. Food Chem Toxicol 48: 1052-1058, 2010.
    • (2010) Food Chem Toxicol , vol.48 , pp. 1052-1058
    • Yang, S.F.1    Chen, M.K.2    Hsieh, Y.S.3
  • 26
    • 79952207441 scopus 로고    scopus 로고
    • Antimetastatic potentials of Dioscorea nipponica on melanoma in vitro and in vivo
    • Ho ML, Hsieh YS, Chen JY, et al: Antimetastatic potentials of Dioscorea nipponica on melanoma in vitro and in vivo. Evid Based Complement Alternat Med 2011: 507920, 2011.
    • (2011) Evid Based Complement Alternat Med , vol.2011 , pp. 507920
    • Ho, M.L.1    Hsieh, Y.S.2    Chen, J.Y.3
  • 27
    • 84865510938 scopus 로고    scopus 로고
    • Antitumor and antimetastatic activities of grape skin polyphenols in a murine model of breast cancer
    • Sun T, Chen QY, Wu LJ, Yao XM and Sun XJ: Antitumor and antimetastatic activities of grape skin polyphenols in a murine model of breast cancer. Food Chem Toxicol 50: 3462-3467, 2012.
    • (2012) Food Chem Toxicol , vol.50 , pp. 3462-3467
    • Sun, T.1    Chen, Q.Y.2    Wu, L.J.3    Yao, X.M.4    Sun, X.J.5
  • 28
    • 84855969619 scopus 로고    scopus 로고
    • Chemopreventive effects of dietary phytochemicals against cancer invasion and metastasis: Phenolic acids, monophenol, polyphenol, and their derivatives
    • Weng CJ and Yen GC: Chemopreventive effects of dietary phytochemicals against cancer invasion and metastasis: phenolic acids, monophenol, polyphenol, and their derivatives. Cancer Treat Rev 38: 76-87, 2012.
    • (2012) Cancer Treat Rev , vol.38 , pp. 76-87
    • Weng, C.J.1    Yen, G.C.2
  • 29
    • 84855181545 scopus 로고    scopus 로고
    • Effects of a Chinese herbal medicine, Guan-Jen-Huang (Aeginetia indica Linn.), on renal cancer cell growth and metastasis
    • Liu YH, Li ML, Hsu MY, et al: Effects of a Chinese herbal medicine, Guan-Jen-Huang (Aeginetia indica Linn.), on renal cancer cell growth and metastasis. Evid Based Complement Alternat Med 2012: 935860, 2012.
    • (2012) Evid Based Complement Alternat Med , vol.2012 , pp. 935860
    • Liu, Y.H.1    Li, M.L.2    Hsu, M.Y.3
  • 30
    • 77952882552 scopus 로고    scopus 로고
    • Ethanol extract of Ocimum sanctum exerts antimetastatic activity through inactivation of matrix metalloproteinase-9 and enhancement of anti-oxidant enzymes
    • Kim SC, Magesh V, Jeong SJ, et al: Ethanol extract of Ocimum sanctum exerts antimetastatic activity through inactivation of matrix metalloproteinase-9 and enhancement of anti-oxidant enzymes. Food Chem Toxicol 48: 1478-1482, 2010.
    • (2010) Food Chem Toxicol , vol.48 , pp. 1478-1482
    • Kim, S.C.1    Magesh, V.2    Jeong, S.J.3
  • 31
    • 33750688244 scopus 로고    scopus 로고
    • Inhibition of tumor invasion and metastasis by aqueous extract of the radix of Platycodon grandiflorum
    • Lee KJ, Kim JY, Choi JH, et al: Inhibition of tumor invasion and metastasis by aqueous extract of the radix of Platycodon grandiflorum. Food Chem Toxicol 44: 1890-1896, 2006.
    • (2006) Food Chem Toxicol , vol.44 , pp. 1890-1896
    • Lee, K.J.1    Kim, J.Y.2    Choi, J.H.3
  • 32
    • 84861437236 scopus 로고    scopus 로고
    • Polyphenolic extract isolated from Korean Lonicera japonica Thunb. Induces G2/M cell cycle arrest and apoptosis in HepG2 cells: Involvements of PI3K/Akt and MAPKs
    • Park HS, Park KI, Lee DH, et al: Polyphenolic extract isolated from Korean Lonicera japonica Thunb. induces G2/M cell cycle arrest and apoptosis in HepG2 cells: involvements of PI3K/Akt and MAPKs. Food Chem Toxicol 50: 2407-2416, 2012.
    • (2012) Food Chem Toxicol , vol.50 , pp. 2407-2416
    • Park, H.S.1    Park, K.I.2    Lee, D.H.3
  • 33
    • 80052376690 scopus 로고    scopus 로고
    • Baicalein inhibits the migration and invasive properties of human hepatoma cells
    • Chiu YW, Lin TH, Huang WS, et al: Baicalein inhibits the migration and invasive properties of human hepatoma cells. Toxicol Appl Pharmacol 255: 316-326, 2011.
    • (2011) Toxicol Appl Pharmacol , vol.255 , pp. 316-326
    • Chiu, Y.W.1    Lin, T.H.2    Huang, W.S.3
  • 34
    • 0043095357 scopus 로고    scopus 로고
    • Baicalein and baicalin are potent inhibitors of angiogenesis: Inhibition of endothelial cell proliferation, migration and differentiation
    • Liu JJ, Huang TS, Cheng WF and Lu FJ: Baicalein and baicalin are potent inhibitors of angiogenesis: inhibition of endothelial cell proliferation, migration and differentiation. Int J Cancer 106: 559-565, 2003.
    • (2003) Int J Cancer , vol.106 , pp. 559-565
    • Liu, J.J.1    Huang, T.S.2    Cheng, W.F.3    Lu, F.J.4
  • 35
    • 33750331488 scopus 로고    scopus 로고
    • Wogonin suppresses TNF-α-induced MMP-9 expression by blocking the NF-κB activation via MAPK signaling pathways in human aortic smooth muscle cells
    • Lee SO, Jeong YJ, Yu MH, et al: Wogonin suppresses TNF-α-induced MMP-9 expression by blocking the NF-κB activation via MAPK signaling pathways in human aortic smooth muscle cells. Biochem Biophys Res Commun 351: 118-125, 2006.
    • (2006) Biochem Biophys Res Commun , vol.351 , pp. 118-125
    • Lee, S.O.1    Jeong, Y.J.2    Yu, M.H.3
  • 36
    • 84880172411 scopus 로고    scopus 로고
    • Baicalin suppresses migration, invasion and metastasis of breast cancer via p38MAPK signaling pathway
    • Wang XF, Zhou QM, Du J, Zhang H, Lu YY and Su SB: Baicalin suppresses migration, invasion and metastasis of breast cancer via p38MAPK signaling pathway. Anticancer Agents Med Chem 13: 923-931, 2013.
    • (2013) Anticancer Agents Med Chem , vol.13 , pp. 923-931
    • Wang, X.F.1    Zhou, Q.M.2    Du, J.3    Zhang, H.4    Lu, Y.Y.5    Su, S.B.6
  • 37
    • 77749289187 scopus 로고    scopus 로고
    • Decursin inhibits growth of human bladder and colon cancer cells via apoptosis, G1-phase cell cycle arrest and extracellular signal-regulated kinase activation
    • Kim WJ, Lee SJ, Choi YD and Moon SK: Decursin inhibits growth of human bladder and colon cancer cells via apoptosis, G1-phase cell cycle arrest and extracellular signal-regulated kinase activation. Int J Mol Med 25: 635-641, 2010.
    • (2010) Int J Mol Med , vol.25 , pp. 635-641
    • Kim, W.J.1    Lee, S.J.2    Choi, Y.D.3    Moon, S.K.4
  • 38
    • 84860397350 scopus 로고    scopus 로고
    • Decursin and decursinol from Angelica gigas inhibit the lung metastasis of murine colon carcinoma
    • Son SH, Park KK, Park SK, et al: Decursin and decursinol from Angelica gigas inhibit the lung metastasis of murine colon carcinoma. Phytother Res 25: 959-964, 2011.
    • (2011) Phytother Res , vol.25 , pp. 959-964
    • Son, S.H.1    Park, K.K.2    Park, S.K.3
  • 39
    • 41849124923 scopus 로고    scopus 로고
    • [6]-Gingerol inhibits metastasis of MDA-MB-231 human breast cancer cells
    • Lee HS, Seo EY, Kang NE and Kim WK: [6]-Gingerol inhibits metastasis of MDA-MB-231 human breast cancer cells. J Nutr Biochem 19: 313-319, 2008.
    • (2008) J Nutr Biochem , vol.19 , pp. 313-319
    • Lee, H.S.1    Seo, E.Y.2    Kang, N.E.3    Kim, W.K.4
  • 40
    • 77954520406 scopus 로고    scopus 로고
    • NFκB: A promising target for natural products in cancer chemoprevention
    • Luqman S and Pezzuto JM: NFκB: a promising target for natural products in cancer chemoprevention. Phytother Res 24: 949-963, 2010.
    • (2010) Phytother Res , vol.24 , pp. 949-963
    • Luqman, S.1    Pezzuto, J.M.2


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