Antitumor and antimetastatic activities of grape skin polyphenols in a murine model of breast cancer

Food and Chemical Toxicology

Volumn 50, Issue 10, 2012, Pages 3462-3467

  Sun, T ^a   Chen, Q Y ^a   Wu, L J ^a   Yao, X M ^a   Sun, X J ^a  

^a SHANGHAI JIAO TONG UNIVERSITY   (China)

Author keywords

4T1 mammary carcinoma; Grape skin polyphenols; MAPK pathway; Metastasis; Migration; PI3k Akt pathway

Indexed keywords

ANTHOCYANIN; CATECHIN; EPICATECHIN; EPICATECHIN GALLATE; FLAVONOID; GRAPE SKIN EXTRACT; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOINOSITIDE DEPENDENT PROTEIN KINASE 1; PLANT EXTRACT; POLYPHENOL; PROCYANIDIN; PROTEIN KINASE B; QUERCETIN; RESVERATROL; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BREAST CANCER; BREAST METASTASIS; CANCER SURVIVAL; CELL MIGRATION; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOSE RESPONSE; DRUG SCREENING; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; FEMALE; GRAPE; GRAPE SKIN; HISTOPATHOLOGY; LUNG METASTASIS; METASTASIS INHIBITION; MOUSE; NONHUMAN; SIGNAL TRANSDUCTION;

ANIMALS; CELL LINE, TUMOR; FEMALE; FRUIT; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE EXPRESSION REGULATION, NEOPLASTIC; MAMMARY NEOPLASMS, ANIMAL; MICE; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; PHOSPHATIDYLINOSITOL 3-KINASES; POLYPHENOLS; VITIS;

MURINAE; MUS; VITACEAE;

EID: 84865510938     PISSN: 02786915     EISSN: 18736351     Source Type: Journal    
DOI: 10.1016/j.fct.2012.07.037     Document Type: Article

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