Optimization of micromilling microchannels on a polycarbonate substrate

International Journal of Precision Engineering and Manufacturing

Volumn 15, Issue 1, 2014, Pages 149-154

  Chen, Pin Chuan ^a   Pan, Chang Wei ^a   Lee, Wei Chen ^a   Li, Kuan Ming ^b  

^a NATIONAL TAIWAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Taiwan)

^b NATIONAL TAIWAN UNIVERSITY   (Taiwan)

Author keywords

Micromilling; Polymer microfluidic device; Rapid prototyping

Indexed keywords

FACTOR ANALYSIS; FLUIDIC DEVICES; MICROMACHINING; MILLING (MACHINING); MULTIVARIANT ANALYSIS; POLYCARBONATES; QUALITY CONTROL; RAPID PROTOTYPING; SURFACE ROUGHNESS; USER INTERFACES;

COMPLICATED STRUCTURES; DEPTH OF CUT; FABRICATION PROCESS; MICRO MILLING; OPTIMAL CUTTING; POLYCARBONATE SUBSTRATES; POLYMER MICROFLUIDIC DEVICES; SPINDLE SPEED;

MICROFLUIDICS;

EID: 84891895460     PISSN: 22347593     EISSN: 20054602     Source Type: Journal    
DOI: 10.1007/s12541-013-0318-1     Document Type: Article

References (18)

1. Terry, S. S., Jerman, J. H., and Angell, J. B., "A Gas Chromatographic Air Analyzer Fabricated on a Silicon Wafer," Proc. of IEEE Transactions on Electron Devices, Vol. 26, No. 12, pp. 1880-1886, 1979.
2. Dornfeld, D., Min, S., and Takeuchi, Y., "Recent Advances in Mechanical Micromachining," CIRP Annals - Manufacturing Technology, Vol. 55, No. 2, pp. 745-768, 2006.
3. Xu, B. Y., Yan, X. N., Zhang, J. D., Xu, J. J., and Chen, H. Y., "Glass Etching to Bridge Micro-and Nanofluidics," Lab on a Chip, Vol. 12, No. 2, pp. 381-386, 2012.
4. Park, D. S., Chen, P. C., You, B. H., Kim, N., Park, T., and et al., "Titer Plate Formatted Continuous Flow Thermal Reactors for High Throughput Applications: Fabrication and Testing," Journal of Micromechanics and Microengineering, Vol. 20, No. 5, pp. 055003, 2010.
5. Chen, P. C., Park, D. S., You, B. H., Kim, N., Park, T., and et al., "Titer-Plate Formatted Continuous Flow Thermal Reactors: Design and Performance of a Nanoliter Reactor," Sensors and Actuators B: Chemical, Vol. 149, No. 1, pp. 291-300, 2010.
6. Kim, J. A., Lee, J. Y., Seong, S., Cha, S. H., Lee, S. H., and et al., "Fabrication and Characterization of a PDMS-Glass Hybrid Continuous-Flow PCR Chip," Biochemical Engineering Journal, Vol. 29, No. 1, pp. 91-97, 2006.
7. Mecomber, J. S., Hurd, D., and Limbach, P. A., "Enhanced Machining of Micron-Scale Features in Microchip Molding Masters by CNC Milling," International Journal of Machine Tools and Manufacture, Vol. 45, No. 12, pp. 1542-1550, 2005.
8. Mecomber, J. S., Stalcup, A. M., Hurd, D., Halsall, H. B., Heineman, W. R., and et al., "Analytical Performance of Polymer-Based Microfluidic Devices Fabricated by Computer Numerical Controlled Machining," Analytical Chemistry, Vol. 78, No. 3, pp. 936-941, 2006.
9. Becker, H. and Heim, U., "Hot Embossing as a Method for the Fabrication of Polymer High Aspect Ratio Structures," Sensors and Actuators A: Physical, Vol. 83, No. 1, pp. 130-135, 2000.
10. Becker, H. and Gaertner, C., "Polymer Based Micro-Reactors," Reviews in Molecular Biotechnology, Vol. 82, No. 2, pp. 89-99, 2001.
11. Hupert, M. L., Guy, W. J., Llopis, S. D., Shadpour, H., Rani, S., and et al., "Evaluation of Micromilled Metal Mold Masters for the Replication of Microchip Electrophoresis Devices," Microfluidics and Nanofluidics, Vol. 3, No. 1, pp. 1-11, 2007.
12. Park, C. H., Song, C. K., Hwang, J., and Kim, B. S., "Development of an Ultra Precision Machine Tool for Micromachining on Large Surfaces," Int. J. Precis. Eng. Manuf., Vol. 10, No. 4, pp. 85-91, 2009.
13. Vázquez, E., Rodríguez, C. A., Elías-Zúñiga, A., and Ciurana, J., "An Experimental Analysis of Process Parameters to Manufacture Metallic Micro-Channels by Micro-Milling," The International Journal of Advanced Manufacturing Technology, Vol. 51, No. 9-12, pp. 945-955, 2010.
14. Zhang, J. Z., Chen, J. C., and Kirby, E. D., "Surface Roughness Optimization in an End-Milling Operation using the Taguchi Design Method," Journal of Materials Processing Technology, Vol. 184, No. 1, pp. 233-239, 2007.
15. Chen, P. C., Park, D. S., You, B. H., Kim, N., Park, T., and et al., "Titer-Plate Formatted Continuous Flow Thermal Reactors: Design And Performance Of A Nanoliter Reactor," Sensors and Actuators B: Chemical, Vol. 149, No. 1, pp. 291-300, 2010.
16. Wang, Y., Chen, H., He, Q., and Soper, S. A., "A High Performance Polycarbonate Electrophoresis Microchip with Integrated Three Electrode System for End-Channel Amperometric Detection," Electrophoresis, Vol. 29, No. 9, pp. 1881-1888, 2008.
17. You, B. H., Chen, P. C., Park, D. S., Park, S., Nikitopoulos, D. E., and et al., "Passive Micro-Assembly of Modular, Hot Embossed, Polymer Microfluidic Devices using Exact Constraint Design," Journal of Micromechanics and Microengineering, Vol. 19, No. 12, pp. 125025, 2009.
18. Yoon, H. S., Wu, R., Lee, T. M., and Ahn, S. H., "Geometric Optimization of Micro Drills using Taguchi Methods and Response Surface Methodology," Int. J. Precis. Eng. Manuf., Vol. 12, No. 5, pp. 871-875, 2011.