The thyroid receptor modulator KB3495 reduces atherosclerosis independently of total cholesterol in the circulation in ApoE deficient mice

PLoS ONE

Volumn 8, Issue 12, 2013, Pages

  Mörk, Lisa Mari ^a   Rehnmark, Stefan ^b,d   Davoodpour, Padideh ^a,e   Norata, Giuseppe Danilo ^c   Larsson, Lilian ^a   Witt, Michael Robin ^b,d   Malm, Johan ^b,f   Parini, Paolo ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b Karo Bio   (Sweden)

^c UNIVERSITY OF MILAN   (Italy)

^d Axcentua Pharmaceuticals AB   (Sweden)

^e LINKÖPING UNIVERSITY   (Sweden)

^f UPPSALA UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; ANTILIPEMIC AGENT; APOLIPOPROTEIN E; ATORVASTATIN; CHOLESTEROL; CHOLESTEROL ESTER; COLONY STIMULATING FACTOR 1; INTERLEUKIN 1BETA; INTERLEUKIN 6; KB 3495; LIPOPROTEIN; MONOCYTE CHEMOTACTIC PROTEIN 1; STEROL; THYROID HORMONE; THYROID HORMONE RECEPTOR; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; AORTA ATHEROSCLEROSIS; ARTICLE; CHOLESTEROL BLOOD LEVEL; CHOLESTEROL METABOLISM; CIRCULATION; CONTROLLED STUDY; DRUG POTENTIATION; INFLAMMATION; LIPOPROTEIN BLOOD LEVEL; MALE; MOUSE; NONHUMAN; PROTEIN BLOOD LEVEL; STEROL EXCRETION;

ANIMALS; ANTICHOLESTEREMIC AGENTS; APOLIPOPROTEINS B; APOLIPOPROTEINS E; ATHEROSCLEROSIS; BILE ACIDS AND SALTS; BIOLOGICAL TRANSPORT; CYTOKINES; DISEASE MODELS, ANIMAL; DRUG SYNERGISM; FECES; HEPTANOIC ACIDS; MALE; MICE; MICE, KNOCKOUT; MOLECULAR MIMICRY; PLAQUE, ATHEROSCLEROTIC; PYRROLES; THYROID HORMONES;

EID: 84891894217     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0078534     Document Type: Article

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