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Volumn 34, Issue 14, 2006, Pages 3853-3861

Two uniquely arranged thyroid hormone response elements in the far upstream 5′ flanking region confer direct thyroid hormone regulation to the murine cholesterol 7α hydroxylase gene

Author keywords

[No Author keywords available]

Indexed keywords

BILE ACID; CHOLESTEROL; CHOLESTEROL 7ALPHA MONOOXYGENASE; DNA; LIVER X RECEPTOR; RETINOID X RECEPTOR; RETINOID X RECEPTOR ALPHA; THYROID HORMONE; THYROID HORMONE RECEPTOR ALPHA; THYROID HORMONE RECEPTOR BETA; CELL RECEPTOR; CYTOCHROME P450 7A1, MOUSE; DNA BINDING PROTEIN; LIOTHYRONINE; MESSENGER RNA; THYROID HORMONE RECEPTOR;

EID: 33748519257     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkl506     Document Type: Article
Times cited : (38)

References (50)
  • 1
    • 0036668184 scopus 로고    scopus 로고
    • Bile acid regulation of gene expression: Roles of nuclear hormone receptors
    • Chiang,J.Y. (2002) Bile acid regulation of gene expression: Roles of nuclear hormone receptors. Endocr. Rev., 23, 443-463.
    • (2002) Endocr. Rev. , vol.23 , pp. 443-463
    • Chiang, J.Y.1
  • 2
    • 0013199471 scopus 로고    scopus 로고
    • Cholesterol and bile acid metabolism are impaired in mice lacking the nuclear oxysterol receptor LXR alpha
    • Peet,D.J., Turley,S.D., Ma,W., Janowski,B.A., Lobaccaro,J.M., Hammer,R.E. and Mangelsdorf,D.J. (1998) Cholesterol and bile acid metabolism are impaired in mice lacking the nuclear oxysterol receptor LXR alpha. Cell, 93, 693-704.
    • (1998) Cell , vol.93 , pp. 693-704
    • Peet, D.J.1    Turley, S.D.2    Ma, W.3    Janowski, B.A.4    Lobaccaro, J.M.5    Hammer, R.E.6    Mangelsdorf, D.J.7
  • 4
    • 0029805887 scopus 로고    scopus 로고
    • An oxysterol signalling pathway mediated by the nuclear receptor LXR alpha
    • Janowski,B.A., Willy,P.J., Devi,T.R., Falck,J.R. and Mangelsdorf,D.J. (1996) An oxysterol signalling pathway mediated by the nuclear receptor LXR alpha. Nature, 383, 728-731.
    • (1996) Nature , vol.383 , pp. 728-731
    • Janowski, B.A.1    Willy, P.J.2    Devi, T.R.3    Falck, J.R.4    Mangelsdorf, D.J.5
  • 7
    • 0035903105 scopus 로고    scopus 로고
    • The negative effects of bile acids and tumor necrosis factor-alpha on the transcription of cholesterol 7alpha-hydroxylase gene (CYP7A1) converge to hepatic nuclear factor-4: A novel mechanism of feedback regulation of bile acid synthesis mediated by nuclear receptors
    • De Fabiani,E., Mitro,N., Anzulovich,A.C., Pinelli,A., Galli,G. and Crestani,M. (2001) The negative effects of bile acids and tumor necrosis factor-alpha on the transcription of cholesterol 7alpha-hydroxylase gene (CYP7A1) converge to hepatic nuclear factor-4: A novel mechanism of feedback regulation of bile acid synthesis mediated by nuclear receptors. J. Biol. Chem., 276, 30708-30716.
    • (2001) J. Biol. Chem. , vol.276 , pp. 30708-30716
    • De Fabiani, E.1    Mitro, N.2    Anzulovich, A.C.3    Pinelli, A.4    Galli, G.5    Crestani, M.6
  • 8
    • 0346118926 scopus 로고    scopus 로고
    • PGC-1alpha activates CYP7A1 and bile acid biosynthesis
    • Shin,D.J., Campos,J.A., Gil,G. and Osborne,T.F. (2003) PGC-1alpha activates CYP7A1 and bile acid biosynthesis. J. Biol. Chem., 278, 50047-50052.
    • (2003) J. Biol. Chem. , vol.278 , pp. 50047-50052
    • Shin, D.J.1    Campos, J.A.2    Gil, G.3    Osborne, T.F.4
  • 9
    • 0028865447 scopus 로고
    • Transcriptional regulation of rat hepatic low-density lipoprotein receptor and cholesterol 7 alpha hydroxylase by thyroid hormone
    • Ness,G.C. and Lopez,D. (1995) Transcriptional regulation of rat hepatic low-density lipoprotein receptor and cholesterol 7 alpha hydroxylase by thyroid hormone. Arch. Biochem. Biophys., 323, 404-408.
    • (1995) Arch. Biochem. Biophys. , vol.323 , pp. 404-408
    • Ness, G.C.1    Lopez, D.2
  • 10
    • 0028027673 scopus 로고
    • Thyroid hormone rapidly increases cholesterol 7 alpha-hydroxylase mRNA levels in hypophysectomized rats
    • Ness,G.C., Pendelton,L.C. and Zhao,Z. (1994) Thyroid hormone rapidly increases cholesterol 7 alpha-hydroxylase mRNA levels in hypophysectomized rats. Biochim. Biophys. Acta, 1214, 229-233.
    • (1994) Biochim. Biophys. Acta , vol.1214 , pp. 229-233
    • Ness, G.C.1    Pendelton, L.C.2    Zhao, Z.3
  • 11
    • 0025251742 scopus 로고
    • Effect of thyroid hormone on hepatic cholesterol 7 alpha hydroxylase, LDL receptor, HMG-CoA reductase, farnesyl pyrophosphate synthetase and apolipoprotein A-1 mRNA levels in hypophysectomized rats
    • Ness,G.C., Pendleton,L.C., Li,Y.C. and Chiang,J.Y. (1990) Effect of thyroid hormone on hepatic cholesterol 7 alpha hydroxylase, LDL receptor, HMG-CoA reductase, farnesyl pyrophosphate synthetase and apolipoprotein A-1 mRNA levels in hypophysectomized rats. Biochem. Biophys. Res. Commun., 172, 1150-1156.
    • (1990) Biochem. Biophys. Res. Commun. , vol.172 , pp. 1150-1156
    • Ness, G.C.1    Pendleton, L.C.2    Li, Y.C.3    Chiang, J.Y.4
  • 12
    • 0034964207 scopus 로고    scopus 로고
    • Physiological and molecular basis of thyroid hormone action
    • Yen,P.M. (2001) Physiological and molecular basis of thyroid hormone action. Physiol. Rev., 81, 1097-1142.
    • (2001) Physiol. Rev. , vol.81 , pp. 1097-1142
    • Yen, P.M.1
  • 13
    • 0027416347 scopus 로고
    • Thyroid hormone receptors: Multiple forms, multiple possibilities
    • Lazar,M.A. (1993) Thyroid hormone receptors: Multiple forms, multiple possibilities. Endocr. Rev., 14, 184-193.
    • (1993) Endocr. Rev. , vol.14 , pp. 184-193
    • Lazar, M.A.1
  • 14
    • 0025021268 scopus 로고
    • Differential and tissue-specific regulation of the multiple rat c-erbA messenger RNA species by thyroid hormone
    • Hodin,R.A., Lazar,M.A. and Chin,W.W. (1990) Differential and tissue-specific regulation of the multiple rat c-erbA messenger RNA species by thyroid hormone. J. Clin. Invest., 85, 101-105.
    • (1990) J. Clin. Invest. , vol.85 , pp. 101-105
    • Hodin, R.A.1    Lazar, M.A.2    Chin, W.W.3
  • 15
    • 0025936209 scopus 로고
    • Differential DNA binding by monomeric, homodimeric, and potentially heteromeric forms of the thyroid hormone receptor
    • Lazar,M.A., Berrodin,T.J. and Harding,H.P. (1991) Differential DNA binding by monomeric, homodimeric, and potentially heteromeric forms of the thyroid hormone receptor. Mol. Cell. Biol., 11, 5005-5015.
    • (1991) Mol. Cell. Biol. , vol.11 , pp. 5005-5015
    • Lazar, M.A.1    Berrodin, T.J.2    Harding, H.P.3
  • 16
    • 0025812291 scopus 로고
    • Direct repeats as selective response elements for the thyroid hormone, retinoic acid, and vitamin D3 receptors
    • Umesono,K., Murakami,K.K., Thompson,C.C. and Evans,R.M. (1991) Direct repeats as selective response elements for the thyroid hormone, retinoic acid, and vitamin D3 receptors. Cell, 65, 1255-1266.
    • (1991) Cell , vol.65 , pp. 1255-1266
    • Umesono, K.1    Murakami, K.K.2    Thompson, C.C.3    Evans, R.M.4
  • 17
    • 0024833706 scopus 로고
    • Mutations of the rat growth hormone promoter which increase and decrease response to thyroid hormone define a consensus thyroid hormone response element
    • Brent,G.A., Harney,J.W., Chen,Y., Warne,R.L., Moore,D.D. and Larsen,P.R. (1989) Mutations of the rat growth hormone promoter which increase and decrease response to thyroid hormone define a consensus thyroid hormone response element. Mol. Endocrinol., 3, 1996-2004.
    • (1989) Mol. Endocrinol. , vol.3 , pp. 1996-2004
    • Brent, G.A.1    Harney, J.W.2    Chen, Y.3    Warne, R.L.4    Moore, D.D.5    Larsen, P.R.6
  • 18
    • 0029084540 scopus 로고
    • Regulation of phosphoenolpyruvate carboxykinase gene transcription by thyroid hormone involves two distinct binding sites in the promoter
    • Park,E.A., Jerden,D.C. and Bahouth,S.W. (1995) Regulation of phosphoenolpyruvate carboxykinase gene transcription by thyroid hormone involves two distinct binding sites in the promoter. Biochem. J., 309, 913-919.
    • (1995) Biochem. J. , vol.309 , pp. 913-919
    • Park, E.A.1    Jerden, D.C.2    Bahouth, S.W.3
  • 19
    • 0024354839 scopus 로고
    • The rat growth hormone gene contains multiple thyroid response elements
    • Norman,M.F., Lavin,T.N., Baxter,J.D. and West,B.L. (1989) The rat growth hormone gene contains multiple thyroid response elements. J. Biol. Chem., 264, 12063-12073.
    • (1989) J. Biol. Chem. , vol.264 , pp. 12063-12073
    • Norman, M.F.1    Lavin, T.N.2    Baxter, J.D.3    West, B.L.4
  • 20
    • 0025964989 scopus 로고
    • Functional characterization and receptor binding studies of the malic enzyme thyroid hormone response element
    • Desvergne,B., Petty,K.J. and Nikodem,V.M. (1991) Functional characterization and receptor binding studies of the malic enzyme thyroid hormone response element. J. Biol. Chem., 266, 1008-1013.
    • (1991) J. Biol. Chem. , vol.266 , pp. 1008-1013
    • Desvergne, B.1    Petty, K.J.2    Nikodem, V.M.3
  • 21
    • 0027990245 scopus 로고
    • Functional synergism between multiple thyroid hormone response elements regulates hepatic expression of the rat S14 gene
    • Liu,H.C. and Towle,H.C. (1994) Functional synergism between multiple thyroid hormone response elements regulates hepatic expression of the rat S14 gene. Mol. Endocrinol., 8, 1021-1037.
    • (1994) Mol. Endocrinol. , vol.8 , pp. 1021-1037
    • Liu, H.C.1    Towle, H.C.2
  • 22
    • 0001611155 scopus 로고
    • Blood cholesterol values in hyperthyroidism and hypothyroidism - Their significance
    • Mason,R.L., Hunt,H.M. and Hurxthal,L. (1930) Blood cholesterol values in hyperthyroidism and hypothyroidism - their significance. N. Engl. J. Med., 203, 1273-1278.
    • (1930) N. Engl. J. Med. , vol.203 , pp. 1273-1278
    • Mason, R.L.1    Hunt, H.M.2    Hurxthal, L.3
  • 24
    • 0141706620 scopus 로고    scopus 로고
    • Thyroid hormone regulation and cholesterol metabolism are connected through sterol regulatory element-binding protein-2 (SREBP-2)
    • Shin,D.J. and Osborne,T.F. (2003) Thyroid hormone regulation and cholesterol metabolism are connected through sterol regulatory element-binding protein-2 (SREBP-2). J. Biol. Chem., 278, 34114-34118.
    • (2003) J. Biol. Chem. , vol.278 , pp. 34114-34118
    • Shin, D.J.1    Osborne, T.F.2
  • 25
    • 0033650847 scopus 로고    scopus 로고
    • Thyroid hormone receptor beta-deficient mice show complete loss of the normal cholesterol 7alpha-hydroxylase (CYP7A) response to thyroid hormone but display enhanced resistance to dietary cholesterol
    • Gullberg,H., Rudling,M., Forrest,D., Angelin,B. and Vennstrom,B. (2000) Thyroid hormone receptor beta-deficient mice show complete loss of the normal cholesterol 7alpha-hydroxylase (CYP7A) response to thyroid hormone but display enhanced resistance to dietary cholesterol. Mol. Endocrinol., 14, 1739-1749.
    • (2000) Mol. Endocrinol. , vol.14 , pp. 1739-1749
    • Gullberg, H.1    Rudling, M.2    Forrest, D.3    Angelin, B.4    Vennstrom, B.5
  • 26
    • 33644863648 scopus 로고    scopus 로고
    • Cross-talk between thyroid hormone receptor and liver X receptor regulatory pathways is revealed in a thyroid hormone resistance mouse model
    • Hashimoto,K., Cohen,R.N., Yamada,M., Markan,K.R., Monden,T., Satoh,T., Mori,M. and Wondisford,F.E. (2006) Cross-talk between thyroid hormone receptor and liver X receptor regulatory pathways is revealed in a thyroid hormone resistance mouse model. J. Biol. Chem., 281, 295-302.
    • (2006) J. Biol. Chem. , vol.281 , pp. 295-302
    • Hashimoto, K.1    Cohen, R.N.2    Yamada, M.3    Markan, K.R.4    Monden, T.5    Satoh, T.6    Mori, M.7    Wondisford, F.E.8
  • 28
    • 0033081046 scopus 로고    scopus 로고
    • Different functions for the thyroid hormone receptors TRalpha and TRbeta in the control of thyroid hormone production and post-natal development
    • Gauthier,K., Chassande,O., Plateroti,M., Roux,J.P., Legrand,C., Pain,B., Rousset,B., Weiss,R., Trouillas,J. and Samarut,J. (1999) Different functions for the thyroid hormone receptors TRalpha and TRbeta in the control of thyroid hormone production and post-natal development. EMBO J., 18, 623-631.
    • (1999) EMBO J. , vol.18 , pp. 623-631
    • Gauthier, K.1    Chassande, O.2    Plateroti, M.3    Roux, J.P.4    Legrand, C.5    Pain, B.6    Rousset, B.7    Weiss, R.8    Trouillas, J.9    Samarut, J.10
  • 29
    • 0025093836 scopus 로고
    • Thyroid hormone regulates type I deiodinase messenger RNA in rat liver
    • Berry,M.J., Kates,A.L. and Larsen,P.R. (1990) Thyroid hormone regulates type I deiodinase messenger RNA in rat liver, Mol. Endocrinol., 4, 743-748.
    • (1990) Mol. Endocrinol. , vol.4 , pp. 743-748
    • Berry, M.J.1    Kates, A.L.2    Larsen, P.R.3
  • 30
    • 0031756642 scopus 로고    scopus 로고
    • Thyroid hormone action on liver, heart, and energy expenditure in thyroid hormone receptor beta-deficient mice
    • Weiss,R.E., Murata,Y., Cua,K., Hayashi,Y., Seo,H. and Refetoff,S. (1998) Thyroid hormone action on liver, heart, and energy expenditure in thyroid hormone receptor beta-deficient mice. Endocrinology, 139, 4945-4952.
    • (1998) Endocrinology , vol.139 , pp. 4945-4952
    • Weiss, R.E.1    Murata, Y.2    Cua, K.3    Hayashi, Y.4    Seo, H.5    Refetoff, S.6
  • 31
    • 0033026760 scopus 로고    scopus 로고
    • Endogenous bile acids are ligands for the nuclear receptor FXR/BAR
    • Wang,H., Chen,J., Hollister,K., Sowers,L.C. and Forman,B.M. (1999) Endogenous bile acids are ligands for the nuclear receptor FXR/BAR. Mol. Cell, 3, 543-553.
    • (1999) Mol. Cell , vol.3 , pp. 543-553
    • Wang, H.1    Chen, J.2    Hollister, K.3    Sowers, L.C.4    Forman, B.M.5
  • 32
    • 0027237598 scopus 로고
    • Determinants for selective RAR and TR recognition of direct repeat HREs
    • Perlmann,T., Rangarajan,P.N., Umesono,K. and Evans,R.M. (1993) Determinants for selective RAR and TR recognition of direct repeat HREs. Genes. Dev., 7, 1411-1422.
    • (1993) Genes. Dev. , vol.7 , pp. 1411-1422
    • Perlmann, T.1    Rangarajan, P.N.2    Umesono, K.3    Evans, R.M.4
  • 33
    • 0028025654 scopus 로고
    • A novel orphan receptor specific for a subset of thyroid hormone-responsive elements and its interaction with the retinoid/thyroid hormone receptor subfamily
    • Apfel,R., Benbrook,D., Lernhardt,E., Ortiz,M.A., Salbert,G. and Pfahl,M. (1994) A novel orphan receptor specific for a subset of thyroid hormone-responsive elements and its interaction with the retinoid/ thyroid hormone receptor subfamily. Mol. Cell. Biol., 14, 7025-7035.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 7025-7035
    • Apfel, R.1    Benbrook, D.2    Lernhardt, E.3    Ortiz, M.A.4    Salbert, G.5    Pfahl, M.6
  • 34
    • 0023214864 scopus 로고
    • Multiple hormones regulate angiotensinogen messenger ribonucleic acid levels in a rat hepatoma cell line
    • Chang,E. and Perlman,A.J. (1987) Multiple hormones regulate angiotensinogen messenger ribonucleic acid levels in a rat hepatoma cell line. Endocrinology, 121, 513-519.
    • (1987) Endocrinology , vol.121 , pp. 513-519
    • Chang, E.1    Perlman, A.J.2
  • 35
    • 0016699068 scopus 로고
    • Thyroid hormone receptors. Binding characteristics and lack of hormonal dependency for nuclear localization
    • Spindler,B.J., MacLeod,K.M., Ring,J. and Baxter,J.D. (1975) Thyroid hormone receptors. Binding characteristics and lack of hormonal dependency for nuclear localization. J. Biol. Chem., 250, 4113-4119.
    • (1975) J. Biol. Chem. , vol.250 , pp. 4113-4119
    • Spindler, B.J.1    MacLeod, K.M.2    Ring, J.3    Baxter, J.D.4
  • 36
    • 32544439893 scopus 로고    scopus 로고
    • Thyroid hormone-regulated target genes have distinct patterns of coactivator recruitment and histone acetylation
    • Liu,Y., Xia,X., Fondell,J.D. and Yen,P.M. (2006) Thyroid hormone-regulated target genes have distinct patterns of coactivator recruitment and histone acetylation. Mol. Endocrinol., 20, 483-490.
    • (2006) Mol. Endocrinol. , vol.20 , pp. 483-490
    • Liu, Y.1    Xia, X.2    Fondell, J.D.3    Yen, P.M.4
  • 37
    • 0026344983 scopus 로고
    • Molecular basis of thyroid hormone regulation of myelin basic protein gene expression in rodent brain
    • Farsetti,A., Mitsuhashi,T., Desvergne,B., Robbins,J. and Nikodem,V.M. (1991) Molecular basis of thyroid hormone regulation of myelin basic protein gene expression in rodent brain. J. Biol. Chem., 266, 23226-23232.
    • (1991) J. Biol. Chem. , vol.266 , pp. 23226-23232
    • Farsetti, A.1    Mitsuhashi, T.2    Desvergne, B.3    Robbins, J.4    Nikodem, V.M.5
  • 38
    • 0023712742 scopus 로고
    • Thyroid hormone receptor alpha isoforms generated by alternative splicing differentially activate myosin HC gene transcription
    • Izumo,S. and Mahdavi,V. (1988) Thyroid hormone receptor alpha isoforms generated by alternative splicing differentially activate myosin HC gene transcription. Nature, 334, 539-542.
    • (1988) Nature , vol.334 , pp. 539-542
    • Izumo, S.1    Mahdavi, V.2
  • 40
    • 0025349213 scopus 로고
    • Identification of multiple thyroid hormone response elements located far upstream from the rat S14 promoter
    • Zilz,N.D., Murray,M.B. and Towle,H.C. (1990) Identification of multiple thyroid hormone response elements located far upstream from the rat S14 promoter. J. Biol. Chem., 265, 8136-8143.
    • (1990) J. Biol. Chem. , vol.265 , pp. 8136-8143
    • Zilz, N.D.1    Murray, M.B.2    Towle, H.C.3
  • 41
    • 0036020496 scopus 로고    scopus 로고
    • Requirement for thyroid hormone receptor beta in T3 regulation of cholesterol metabolism in mice
    • Gullberg,H., Rudling,M., Salto,C. Forrest,D., Angelin,B. and Vennstrom,B. (2002) Requirement for thyroid hormone receptor beta in T3 regulation of cholesterol metabolism in mice. Mol. Endocrinol., 16, 1767-1777.
    • (2002) Mol. Endocrinol. , vol.16 , pp. 1767-1777
    • Gullberg, H.1    Rudling, M.2    Salto, C.3    Forrest, D.4    Angelin, B.5    Vennstrom, B.6
  • 42
    • 0026557820 scopus 로고
    • Half-site spacing and orientation determines whether thyroid hormone and retinoic acid receptors and related factors bind to DNA response elements as monomers, homodimers, or heterodimers
    • Forman,B.M., Casanova,J., Raaka,B.M., Ghysdael,J. and Samuels,H.H. (1992) Half-site spacing and orientation determines whether thyroid hormone and retinoic acid receptors and related factors bind to DNA response elements as monomers, homodimers, or heterodimers. Mol. Endocrinol., 6, 429-442.
    • (1992) Mol. Endocrinol. , vol.6 , pp. 429-442
    • Forman, B.M.1    Casanova, J.2    Raaka, B.M.3    Ghysdael, J.4    Samuels, H.H.5
  • 43
    • 0026592518 scopus 로고
    • Retinoid X receptor interacts with nuclear receptors in retinoic acid, thyroid hormone and vitamin D3 signalling
    • Kliewer,S.A., Umesono,K., Mangelsdorf,D.J. and Evans,R.M. (1992) Retinoid X receptor interacts with nuclear receptors in retinoic acid, thyroid hormone and vitamin D3 signalling. Nature, 355, 446-449.
    • (1992) Nature , vol.355 , pp. 446-449
    • Kliewer, S.A.1    Umesono, K.2    Mangelsdorf, D.J.3    Evans, R.M.4
  • 44
    • 0026570217 scopus 로고
    • Purification, cloning, and RXR identity of the HeLa cell factor with which RAR or TR heterodimerizes to bind target sequences efficiently
    • Leid,M., Kastner,P., Lyons,R., Nakshatri,H., Saunders,M., Zacharewski,T., Chen,J.Y., Staub,A., Garnier,J.M., Mader,S. et al. (1992) Purification, cloning, and RXR identity of the HeLa cell factor with which RAR or TR heterodimerizes to bind target sequences efficiently. Cell, 68, 377-395.
    • (1992) Cell , vol.68 , pp. 377-395
    • Leid, M.1    Kastner, P.2    Lyons, R.3    Nakshatri, H.4    Saunders, M.5    Zacharewski, T.6    Chen, J.Y.7    Staub, A.8    Garnier, J.M.9    Mader, S.10
  • 45
    • 0026766654 scopus 로고
    • Binding characteristics of the thyroid hormone receptor homo- and heterodimers to consensus AGGTCA repeat motifs
    • Wahlstrom,G.M., Sjoberg,M., Andersson,M., Nordstrom,K. and Vennstrom,B. (1992) Binding characteristics of the thyroid hormone receptor homo- and heterodimers to consensus AGGTCA repeat motifs. Mol. Endocrinol., 6, 1013-1022.
    • (1992) Mol. Endocrinol. , vol.6 , pp. 1013-1022
    • Wahlstrom, G.M.1    Sjoberg, M.2    Andersson, M.3    Nordstrom, K.4    Vennstrom, B.5
  • 46
    • 0026536522 scopus 로고
    • Retinoid X receptor is an auxiliary protein for thyroid hormone and retinoic acid receptors
    • Zhang,X.K., Hoffmann,B., Tran,P.B., Graupner,G. and Pfahl,M. (1992) Retinoid X receptor is an auxiliary protein for thyroid hormone and retinoic acid receptors. Nature, 355, 441-446.
    • (1992) Nature , vol.355 , pp. 441-446
    • Zhang, X.K.1    Hoffmann, B.2    Tran, P.B.3    Graupner, G.4    Pfahl, M.5
  • 47
    • 0029834337 scopus 로고    scopus 로고
    • Transcriptional regulation of the human cholesterol 7 alpha-hydroxylase gene (CYP7A) in HepG2 cells
    • Wang,D.P., Stroup,D., Marrapodi,M., Crestani,M., Galli,G. and Chiang,J.Y. (1996) Transcriptional regulation of the human cholesterol 7 alpha-hydroxylase gene (CYP7A) in HepG2 cells. J. Lipid. Res., 37, 1831-1841.
    • (1996) J. Lipid. Res. , vol.37 , pp. 1831-1841
    • Wang, D.P.1    Stroup, D.2    Marrapodi, M.3    Crestani, M.4    Galli, G.5    Chiang, J.Y.6
  • 48
    • 0842269844 scopus 로고    scopus 로고
    • Regulation of the human cholesterol 7alpha-hydroxylase gene (CYP7A1) by thyroid hormone in transgenic mice
    • Drover,V.A. and Agellon,L.B. (2004) Regulation of the human cholesterol 7alpha-hydroxylase gene (CYP7A1) by thyroid hormone in transgenic mice. Endocrinology, 145, 574-581.
    • (2004) Endocrinology , vol.145 , pp. 574-581
    • Drover, V.A.1    Agellon, L.B.2
  • 49
    • 0033554057 scopus 로고    scopus 로고
    • Hepatocyte nuclear factor 1 binds to and transactivates the human but not the rat CYP7A1 promoter
    • Chen,J., Cooper,A.D. and Levy-Wilson,B. (1999) Hepatocyte nuclear factor 1 binds to and transactivates the human but not the rat CYP7A1 promoter. Biochem. Biophys. Res. Commun., 260, 829-834.
    • (1999) Biochem. Biophys. Res. Commun. , vol.260 , pp. 829-834
    • Chen, J.1    Cooper, A.D.2    Levy-Wilson, B.3
  • 50
    • 0036137808 scopus 로고    scopus 로고
    • A distinct thyroid hormone response element mediates repression of the human cholesterol 7alpha-hydroxylase (CYP7A1) gene promoter
    • Drover,V.A., Wong,N.C. and Agellon,L.B. (2002) A distinct thyroid hormone response element mediates repression of the human cholesterol 7alpha-hydroxylase (CYP7A1) gene promoter. Mol. Endocrinol., 16, 14-23.
    • (2002) Mol. Endocrinol. , vol.16 , pp. 14-23
    • Drover, V.A.1    Wong, N.C.2    Agellon, L.B.3


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