|
|
Volumn 24, Issue 2, 2014, Pages 601-603
|
|
Synthesis and anti-proliferative activity of aromatic substituted 5-((1-benzyl-1H-indol-3-yl)methylene)-1,3-dimethylpyrimidine-2,4,6(1H,3H,5H) -trione analogs against human tumor cell lines
|
|
Author keywords
Dimethylbarbituric acid; Growth inhibitory activity (GI50); Lethal concentration (LC50); N Benzyl indole; Percentage growth inhibition
|
|
Indexed keywords
5 [(1 BENZYL 1H INDOL 3 YL)METHYLENE] 1,3 DIMETHYLPYRIMIDINE 2,4,6(1H,3H,5H) TRIONE DERIVATIVE;
ANTINEOPLASTIC AGENT;
BARBITURIC ACID DERIVATIVE;
BENZYL DERIVATIVE;
INDOLE DERIVATIVE;
UNCLASSIFIED DRUG;
5 [(1 BENZYL 1 H INDOL 3 YL)METHYLENE] 1,3 DIMETHYLPYRIMIDINE 2,4,6 (1H,3H,5H)TRIONE DERIVATIVE;
ANTIPROLIFERATIVE ACTIVITY;
ARTICLE;
BREAST CANCER;
CANCER CELL CULTURE;
CANCER INHIBITION;
COLON CANCER;
CONCENTRATION RESPONSE;
CONTROLLED STUDY;
DRUG CYTOTOXICITY;
DRUG EXPOSURE;
DRUG POTENCY;
DRUG SYNTHESIS;
FEMALE;
HUMAN;
HUMAN CELL;
IN VITRO STUDY;
KIDNEY CANCER;
LUNG NON SMALL CELL CANCER;
MELANOMA CELL;
OPTICAL DENSITY;
OVARY CANCER;
ANTINEOPLASTIC ACTIVITY;
BREAST CANCER CELL LINE;
CANCER CELL LINE;
CENTRAL NERVOUS SYSTEM TUMOR;
DRUG SCREENING;
LEUKEMIA CELL LINE;
LUNG CANCER CELL LINE;
MELANOMA CELL LINE;
NON SMALL CELL LUNG CANCER;
OVARIAN CANCER CELL LINE;
RENAL CANCER CELL LINE;
DIMETHYLBARBITURIC ACID;
GROWTH INHIBITORY ACTIVITY (GI(50));
LETHAL CONCENTRATION (LC(50));
N-BENZYL INDOLE;
PERCENTAGE GROWTH INHIBITION;
ANTINEOPLASTIC AGENTS;
CELL LINE, TUMOR;
CELL PROLIFERATION;
DRUG SCREENING ASSAYS, ANTITUMOR;
HUMANS;
PYRIMIDINES;
|
|
EID: 84891856889
PISSN: 0960894X
EISSN: 14643405
Source Type: Journal
DOI: 10.1016/j.bmcl.2013.12.013 Document Type: Article |
|
Times cited : (41)
|
|
References (14)
|
