Novel substituted (Z)-2-(N-benzylindol-3-ylmethylene)quinuclidin-3-one and (Z)-(±)-2-(N-benzylindol-3-ylmethylene)quinuclidin-3-ol derivatives as potent thermal sensitizing agents

Bioorganic and Medicinal Chemistry Letters

Volumn 17, Issue 24, 2007, Pages 6821-6824

  Sonar, Vijayakumar N ^a   Thirupathi Reddy, Y ^a   Sekhar, Konjeti R ^b   Sasi, Soumya ^b   Freeman, Michael L ^b   Crooks, Peter A ^a  

^a University of Kentucky   (United States)

^b VANDERBILT INGRAM CANCER CENTER   (United States)

Author keywords

Indolylquinuclidin 3 ols; Indolylquinuclidin 3 ones; Thermal sensitization

Indexed keywords

2 (N BENZENESULFONYLINDOL 3 YLMETHYLENE)QUINUCLIDIN 3 OL; 2 (N BENZYLINDOL 3 YLMETHYLENE)QUINUCLIDIN 3 OL; 2 (N BENZYLINDOL 3 YLMETHYLENE)QUINUCLIDIN 3 OL DERIVATIVE; 2 (N BENZYLINDOL 3 YLMETHYLENE)QUINUCLIDIN 3 ONE; 2 (N BENZYLINDOL 3 YLMETHYLENE)QUINUCLIDIN 3 ONE DERIVATIVE; QUINUCLIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CELL STRAIN HT29; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG SYNTHESIS; HEAT SENSITIVITY; HUMAN; HUMAN CELL; HYPERTHERMIC THERAPY; STRUCTURE ACTIVITY RELATION;

CELL LINE, TUMOR; CELL SURVIVAL; HUMANS; MOLECULAR STRUCTURE; QUINUCLIDINES; RADIATION-SENSITIZING AGENTS; STRUCTURE-ACTIVITY RELATIONSHIP; TEMPERATURE;

EID: 35848951590     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2007.10.035     Document Type: Article

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