5-((1-Aroyl-1H-indol-3-yl)methylene)-2-thioxodihydropyrimidine-4,6(1H,5H) -diones as potential anticancer agents with anti-inflammatory properties

Bioorganic and Medicinal Chemistry Letters

Volumn 23, Issue 5, 2013, Pages 1442-1446

  Penthala, Narsimha Reddy ^a   Ponugoti, Purushothama Rao ^a   Kasam, Vinod ^a   Crooks, Peter A ^a  

^a UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

Author keywords

Anti inflammatory agents; In vitro cytotoxicity; N Benzoyl indole 3 carboxaldehydes; N Naphthoylindole 3 carboxaldehydes; Thiobarbituric acid

Indexed keywords

5 [(1 AROYL 1H INDOL 3 YL)METHYLENE] 2 THIOXODIHYDROPYRIMIDINE 4,6(1H,5H)DIONE DERIVATIVE; ANTIINFLAMMATORY AGENT; ANTINEOPLASTIC AGENT; CYCLOOXYGENASE 2 INHIBITOR; HYDROGEN; UNCLASSIFIED DRUG;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; CANCER CELL CULTURE; CANCER THERAPY; DRUG STRUCTURE; HUMAN; HUMAN CELL; HYDROGEN BOND; HYDROPHOBICITY; MELANOMA CELL; MOLECULAR DOCKING;

ANTI-INFLAMMATORY AGENTS; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; PYRIMIDINES; SULFHYDRYL COMPOUNDS;

EID: 84873701065     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2012.12.053     Document Type: Article

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