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Volumn 13, Issue , 2013, Pages

Combination of Albendazole and 2-Methoxyestradiol significantly improves the survival of HCT-116 tumor-bearing nude mice

Author keywords

2 Methoxyestradiol; Albendazole; Combination therapy; Microtubule targeting agents

Indexed keywords

2 METHOXYESTRADIOL; ALBENDAZOLE; CASPASE 3; CASPASE 8; CASPASE 9; COLCHICINE; PACLITAXEL; TUBULIN; VASCULOTROPIN; VINBLASTINE;

EID: 84874053045     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/1471-2407-13-86     Document Type: Article
Times cited : (34)

References (47)
  • 1
    • 76549129820 scopus 로고    scopus 로고
    • Drug combination studies and their synergy quantification using the Chou-Talalay method
    • 10.1158/0008-5472.CAN-09-1947, 20068163
    • Chou TC. Drug combination studies and their synergy quantification using the Chou-Talalay method. Cancer Res 2010, 70(2):440-446. 10.1158/0008-5472.CAN-09-1947, 20068163.
    • (2010) Cancer Res , vol.70 , Issue.2 , pp. 440-446
    • Chou, T.C.1
  • 2
    • 77950608347 scopus 로고    scopus 로고
    • Microtubule targeting agents: from biophysics to proteomics
    • 10.1007/s00018-009-0245-6, 20107862
    • Calligaris D, Verdier-Pinard P, Devred F, Villard C, Braguer D, Lafitte D. Microtubule targeting agents: from biophysics to proteomics. Cell Mol Life Sci 2010, 67(7):1089-1104. 10.1007/s00018-009-0245-6, 20107862.
    • (2010) Cell Mol Life Sci , vol.67 , Issue.7 , pp. 1089-1104
    • Calligaris, D.1    Verdier-Pinard, P.2    Devred, F.3    Villard, C.4    Braguer, D.5    Lafitte, D.6
  • 3
    • 50349097617 scopus 로고    scopus 로고
    • Rapid chemotherapy-induced acute endothelial progenitor cell mobilization: implications for antiangiogenic drugs as chemosensitizing agents
    • 10.1016/j.ccr.2008.08.001, 2565587, 18772115
    • Shaked Y, Henke E, Roodhart JM, Mancuso P, Langenberg MH, Colleoni M, Daenen LG, Man S, Xu P, Emmenegger U. Rapid chemotherapy-induced acute endothelial progenitor cell mobilization: implications for antiangiogenic drugs as chemosensitizing agents. Cancer Cell 2008, 14(3):263-273. 10.1016/j.ccr.2008.08.001, 2565587, 18772115.
    • (2008) Cancer Cell , vol.14 , Issue.3 , pp. 263-273
    • Shaked, Y.1    Henke, E.2    Roodhart, J.M.3    Mancuso, P.4    Langenberg, M.H.5    Colleoni, M.6    Daenen, L.G.7    Man, S.8    Xu, P.9    Emmenegger, U.10
  • 4
    • 0035836793 scopus 로고    scopus 로고
    • In vitro and in vivo suppression of growth of hepatocellular carcinoma cells by albendazole
    • 10.1016/S0304-3835(01)00382-2, 11248417
    • Pourgholami MH, Woon L, Almajd R, Akhter J, Bowery P, Morris DL. In vitro and in vivo suppression of growth of hepatocellular carcinoma cells by albendazole. Cancer Lett 2001, 165(1):43-49. 10.1016/S0304-3835(01)00382-2, 11248417.
    • (2001) Cancer Lett , vol.165 , Issue.1 , pp. 43-49
    • Pourgholami, M.H.1    Woon, L.2    Almajd, R.3    Akhter, J.4    Bowery, P.5    Morris, D.L.6
  • 5
    • 17644414121 scopus 로고    scopus 로고
    • Antitumor activity of albendazole against the human colorectal cancer cell line HT-29: in vitro and in a xenograft model of peritoneal carcinomatosis
    • 10.1007/s00280-004-0927-6, 15565325
    • Pourgholami MH, Akhter J, Wang L, Lu Y, Morris DL. Antitumor activity of albendazole against the human colorectal cancer cell line HT-29: in vitro and in a xenograft model of peritoneal carcinomatosis. Cancer Chemother Pharmacol 2005, 55(5):425-432. 10.1007/s00280-004-0927-6, 15565325.
    • (2005) Cancer Chemother Pharmacol , vol.55 , Issue.5 , pp. 425-432
    • Pourgholami, M.H.1    Akhter, J.2    Wang, L.3    Lu, Y.4    Morris, D.L.5
  • 6
    • 33645661534 scopus 로고    scopus 로고
    • Albendazole: a potent inhibitor of vascular endothelial growth factor and malignant ascites formation in OVCAR-3 tumor-bearing nude mice
    • 10.1158/1078-0432.CCR-05-1181, 16551879
    • Pourgholami MH, Yan Cai Z, Lu Y, Wang L, Morris DL. Albendazole: a potent inhibitor of vascular endothelial growth factor and malignant ascites formation in OVCAR-3 tumor-bearing nude mice. Clin Cancer Res 2006, 12(6):1928-1935. 10.1158/1078-0432.CCR-05-1181, 16551879.
    • (2006) Clin Cancer Res , vol.12 , Issue.6 , pp. 1928-1935
    • Pourgholami, M.H.1    Yan Cai, Z.2    Lu, Y.3    Wang, L.4    Morris, D.L.5
  • 7
    • 0018703882 scopus 로고
    • The interaction of benzimidazole carbamates with mammalian microtobule protein
    • 10.1016/0006-2952(79)90049-2, 518680
    • Ireland CM, Gull K, Gutteridge WE, Pogson CI. The interaction of benzimidazole carbamates with mammalian microtobule protein. Biochem Pharmacol 1979, 28(17):2680-2682. 10.1016/0006-2952(79)90049-2, 518680.
    • (1979) Biochem Pharmacol , vol.28 , Issue.17 , pp. 2680-2682
    • Ireland, C.M.1    Gull, K.2    Gutteridge, W.E.3    Pogson, C.I.4
  • 8
    • 0021839810 scopus 로고
    • Structure-activity relationships of benzimidazole carbamates as inhibitors of mammalian tubulin, in vitro
    • 10.1016/0006-2952(85)90611-2, 3985991
    • Lacey E, Watson TR. Structure-activity relationships of benzimidazole carbamates as inhibitors of mammalian tubulin, in vitro. Biochem Pharmacol 1985, 34(7):1073-1077. 10.1016/0006-2952(85)90611-2, 3985991.
    • (1985) Biochem Pharmacol , vol.34 , Issue.7 , pp. 1073-1077
    • Lacey, E.1    Watson, T.R.2
  • 9
    • 1942438028 scopus 로고    scopus 로고
    • Microtubules as a target for anticancer drugs
    • 10.1038/nrc1317, 15057285
    • Jordan MA, Wilson L. Microtubules as a target for anticancer drugs. Nat Rev Cancer 2004, 4(4):253-265. 10.1038/nrc1317, 15057285.
    • (2004) Nat Rev Cancer , vol.4 , Issue.4 , pp. 253-265
    • Jordan, M.A.1    Wilson, L.2
  • 11
    • 0032484528 scopus 로고    scopus 로고
    • Combinations of paclitaxel and vinblastine and their effects on tubulin polymerization and cellular cytotoxicity: characterization of a synergistic schedule
    • 10.1002/(SICI)1097-0215(19980105)75:1<57::AID-IJC10>3.0.CO;2-A, 9426691
    • Giannakakou P, Villalba L, Li H, Poruchynsky M, Fojo T. Combinations of paclitaxel and vinblastine and their effects on tubulin polymerization and cellular cytotoxicity: characterization of a synergistic schedule. Int J Cancer 1998, 75(1):57-63. 10.1002/(SICI)1097-0215(19980105)75:1<57::AID-IJC10>3.0.CO;2-A, 9426691.
    • (1998) Int J Cancer , vol.75 , Issue.1 , pp. 57-63
    • Giannakakou, P.1    Villalba, L.2    Li, H.3    Poruchynsky, M.4    Fojo, T.5
  • 12
    • 84867000700 scopus 로고    scopus 로고
    • Complexation of Albendazole with Hydroxypropyl-beta-Cyclodextrin Significantly Improves its Pharmacokinetic Profile, Cell Cytotoxicity and Antitumor Efficacy in Nude Mice
    • Ehteda A, Galettis P, Chu SW, Pillai K, Morris DL. Complexation of Albendazole with Hydroxypropyl-beta-Cyclodextrin Significantly Improves its Pharmacokinetic Profile, Cell Cytotoxicity and Antitumor Efficacy in Nude Mice. Anticancer Res 2012, 32(9):3659-3666.
    • (2012) Anticancer Res , vol.32 , Issue.9 , pp. 3659-3666
    • Ehteda, A.1    Galettis, P.2    Chu, S.W.3    Pillai, K.4    Morris, D.L.5
  • 13
    • 2942685341 scopus 로고    scopus 로고
    • Role of hypoxia-inducible factor 1alpha in gastric cancer cell growth, angiogenesis, and vessel maturation
    • 10.1093/jnci/djh168, 15199114
    • Stoeltzing O, McCarty MF, Wey JS, Fan F, Liu W, Belcheva A, Bucana CD, Semenza GL, Ellis LM. Role of hypoxia-inducible factor 1alpha in gastric cancer cell growth, angiogenesis, and vessel maturation. J Natl Cancer Inst 2004, 96(12):946-956. 10.1093/jnci/djh168, 15199114.
    • (2004) J Natl Cancer Inst , vol.96 , Issue.12 , pp. 946-956
    • Stoeltzing, O.1    McCarty, M.F.2    Wey, J.S.3    Fan, F.4    Liu, W.5    Belcheva, A.6    Bucana, C.D.7    Semenza, G.L.8    Ellis, L.M.9
  • 15
    • 75849159018 scopus 로고    scopus 로고
    • A theory of microtubule catastrophes and their regulation
    • 10.1073/pnas.0910774106, 2795527, 19948965
    • Brun L, Rupp B, Ward JJ, Nedelec F. A theory of microtubule catastrophes and their regulation. Proc Natl Acad Sci USA 2009, 106(50):21173-21178. 10.1073/pnas.0910774106, 2795527, 19948965.
    • (2009) Proc Natl Acad Sci USA , vol.106 , Issue.50 , pp. 21173-21178
    • Brun, L.1    Rupp, B.2    Ward, J.J.3    Nedelec, F.4
  • 18
    • 0026524697 scopus 로고
    • Estramustine and vinblastine: use of prostate specific antigen as a clinical trial end point for hormone refractory prostatic cancer
    • Seidman AD, Scher HI, Petrylak D, Dershaw DD, Curley T. Estramustine and vinblastine: use of prostate specific antigen as a clinical trial end point for hormone refractory prostatic cancer. J Urol 1992, 147(3 Pt 2):931-934.
    • (1992) J Urol , vol.147 , Issue.3 PART 2 , pp. 931-934
    • Seidman, A.D.1    Scher, H.I.2    Petrylak, D.3    Dershaw, D.D.4    Curley, T.5
  • 20
    • 0029021646 scopus 로고
    • Vinorelbine tartrate and paclitaxel combinations: enhanced activity against in vivo P388 murine leukemia cells
    • 10.1093/jnci/87.14.1072, 7616599
    • Knick VC, Eberwein DJ, Miller CG. Vinorelbine tartrate and paclitaxel combinations: enhanced activity against in vivo P388 murine leukemia cells. J Natl Cancer Inst 1995, 87(14):1072-1077. 10.1093/jnci/87.14.1072, 7616599.
    • (1995) J Natl Cancer Inst , vol.87 , Issue.14 , pp. 1072-1077
    • Knick, V.C.1    Eberwein, D.J.2    Miller, C.G.3
  • 21
    • 0029103212 scopus 로고
    • Simultaneous combination of microtubule depolymerizing and stabilizing agents acts at low doses
    • 10.1097/00001813-199508000-00006, 7579557
    • Garcia P, Braguer D, Carles G, Briand C. Simultaneous combination of microtubule depolymerizing and stabilizing agents acts at low doses. Anticancer Drugs 1995, 6(4):533-544. 10.1097/00001813-199508000-00006, 7579557.
    • (1995) Anticancer Drugs , vol.6 , Issue.4 , pp. 533-544
    • Garcia, P.1    Braguer, D.2    Carles, G.3    Briand, C.4
  • 23
    • 3142723291 scopus 로고    scopus 로고
    • Synergistic suppression of microtubule dynamics by discodermolide and paclitaxel in non-small cell lung carcinoma cells
    • 10.1158/0008-5472.CAN-04-0693, 15256469
    • Honore S, Kamath K, Braguer D, Horwitz SB, Wilson L, Briand C, Jordan MA. Synergistic suppression of microtubule dynamics by discodermolide and paclitaxel in non-small cell lung carcinoma cells. Cancer Res 2004, 64(14):4957-4964. 10.1158/0008-5472.CAN-04-0693, 15256469.
    • (2004) Cancer Res , vol.64 , Issue.14 , pp. 4957-4964
    • Honore, S.1    Kamath, K.2    Braguer, D.3    Horwitz, S.B.4    Wilson, L.5    Briand, C.6    Jordan, M.A.7
  • 24
    • 0033920430 scopus 로고    scopus 로고
    • Rapid colchicine competition-binding scintillation proximity assay using biotin-labeled tubulin
    • Tahir SK, Kovar P, Rosenberg SH, Ng SC. Rapid colchicine competition-binding scintillation proximity assay using biotin-labeled tubulin. Biotechniques 2000, 29(1):156-160.
    • (2000) Biotechniques , vol.29 , Issue.1 , pp. 156-160
    • Tahir, S.K.1    Kovar, P.2    Rosenberg, S.H.3    Ng, S.C.4
  • 25
    • 0018818340 scopus 로고
    • Inhibition of tubulin polymerization by mebendazole
    • 10.1016/0006-291X(80)90349-6, 7356473
    • Laclette JP, Guerra G, Zetina C. Inhibition of tubulin polymerization by mebendazole. Biochem Biophys Res Commun 1980, 92(2):417-423. 10.1016/0006-291X(80)90349-6, 7356473.
    • (1980) Biochem Biophys Res Commun , vol.92 , Issue.2 , pp. 417-423
    • Laclette, J.P.1    Guerra, G.2    Zetina, C.3
  • 26
    • 2542603198 scopus 로고    scopus 로고
    • Antimitotic antifungal compound benomyl inhibits brain microtubule polymerization and dynamics and cancer cell proliferation at mitosis, by binding to a novel site in tubulin
    • 10.1021/bi036112v, 15157098
    • Gupta K, Bishop J, Peck A, Brown J, Wilson L, Panda D. Antimitotic antifungal compound benomyl inhibits brain microtubule polymerization and dynamics and cancer cell proliferation at mitosis, by binding to a novel site in tubulin. Biochemistry 2004, 43(21):6645-6655. 10.1021/bi036112v, 15157098.
    • (2004) Biochemistry , vol.43 , Issue.21 , pp. 6645-6655
    • Gupta, K.1    Bishop, J.2    Peck, A.3    Brown, J.4    Wilson, L.5    Panda, D.6
  • 27
    • 57449091909 scopus 로고    scopus 로고
    • Benomyl and colchicine synergistically inhibit cell proliferation and mitosis: evidence of distinct binding sites for these agents in tubulin
    • 10.1021/bi801136q, 19049291
    • Clement MJ, Rathinasamy K, Adjadj E, Toma F, Curmi PA, Panda D. Benomyl and colchicine synergistically inhibit cell proliferation and mitosis: evidence of distinct binding sites for these agents in tubulin. Biochemistry 2008, 47(49):13016-13025. 10.1021/bi801136q, 19049291.
    • (2008) Biochemistry , vol.47 , Issue.49 , pp. 13016-13025
    • Clement, M.J.1    Rathinasamy, K.2    Adjadj, E.3    Toma, F.4    Curmi, P.A.5    Panda, D.6
  • 29
    • 71949100927 scopus 로고    scopus 로고
    • Potent inhibition of tubulin polymerisation and proliferation of paclitaxel-resistant 1A9PTX22 human ovarian cancer cells by albendazole
    • Chu SW, Badar S, Morris DL, Pourgholami MH. Potent inhibition of tubulin polymerisation and proliferation of paclitaxel-resistant 1A9PTX22 human ovarian cancer cells by albendazole. Anticancer Res 2009, 29(10):3791-3796.
    • (2009) Anticancer Res , vol.29 , Issue.10 , pp. 3791-3796
    • Chu, S.W.1    Badar, S.2    Morris, D.L.3    Pourgholami, M.H.4
  • 30
    • 0029155318 scopus 로고
    • Kinetic stabilization of microtubule dynamics at steady state in vitro by substoichiometric concentrations of tubulin-colchicine complex
    • 10.1021/bi00031a014, 7632691
    • Panda D, Daijo JE, Jordan MA, Wilson L. Kinetic stabilization of microtubule dynamics at steady state in vitro by substoichiometric concentrations of tubulin-colchicine complex. Biochemistry 1995, 34(31):9921-9929. 10.1021/bi00031a014, 7632691.
    • (1995) Biochemistry , vol.34 , Issue.31 , pp. 9921-9929
    • Panda, D.1    Daijo, J.E.2    Jordan, M.A.3    Wilson, L.4
  • 31
    • 0015102930 scopus 로고
    • Are cytoplasmic microtubules heteropolymers?
    • 10.1073/pnas.68.8.1762, 389288, 5288762
    • Bryan J, Wilson L. Are cytoplasmic microtubules heteropolymers?. Proc Natl Acad Sci USA 1971, 68(8):1762-1766. 10.1073/pnas.68.8.1762, 389288, 5288762.
    • (1971) Proc Natl Acad Sci USA , vol.68 , Issue.8 , pp. 1762-1766
    • Bryan, J.1    Wilson, L.2
  • 32
    • 0029360519 scopus 로고
    • Microtubule dynamics: taking aim at a moving target
    • 10.1016/1074-5521(95)90119-1, 9383460
    • Wilson L, Jordan MA. Microtubule dynamics: taking aim at a moving target. Chem Biol 1995, 2(9):569-573. 10.1016/1074-5521(95)90119-1, 9383460.
    • (1995) Chem Biol , vol.2 , Issue.9 , pp. 569-573
    • Wilson, L.1    Jordan, M.A.2
  • 33
    • 0034595187 scopus 로고    scopus 로고
    • Suppression of microtubule dynamic instability and treadmilling by deuterium oxide
    • 10.1021/bi992217f, 10819973
    • Panda D, Chakrabarti G, Hudson J, Pigg K, Miller HP, Wilson L, Himes RH. Suppression of microtubule dynamic instability and treadmilling by deuterium oxide. Biochemistry 2000, 39(17):5075-5081. 10.1021/bi992217f, 10819973.
    • (2000) Biochemistry , vol.39 , Issue.17 , pp. 5075-5081
    • Panda, D.1    Chakrabarti, G.2    Hudson, J.3    Pigg, K.4    Miller, H.P.5    Wilson, L.6    Himes, R.H.7
  • 34
    • 0034071993 scopus 로고    scopus 로고
    • Discodermolide: just another microtubule-stabilizing agent? No! A lesson in synergy
    • Giannakakou P, Fojo T. Discodermolide: just another microtubule-stabilizing agent? No! A lesson in synergy. Clin Cancer Res 2000, 6(5):1613-1615.
    • (2000) Clin Cancer Res , vol.6 , Issue.5 , pp. 1613-1615
    • Giannakakou, P.1    Fojo, T.2
  • 36
    • 0026645572 scopus 로고
    • Kinetics of colchicine binding to purified beta-tubulin isotypes from bovine brain
    • Banerjee A, Luduena RF. Kinetics of colchicine binding to purified beta-tubulin isotypes from bovine brain. J Biol Chem 1992, 267(19):13335-13339.
    • (1992) J Biol Chem , vol.267 , Issue.19 , pp. 13335-13339
    • Banerjee, A.1    Luduena, R.F.2
  • 37
    • 3543092021 scopus 로고    scopus 로고
    • Pathways of apoptotic and non-apoptotic death in tumour cells
    • 10.1038/nrc1412, 15286739
    • Okada H, Mak TW. Pathways of apoptotic and non-apoptotic death in tumour cells. Nat Rev Cancer 2004, 4(8):592-603. 10.1038/nrc1412, 15286739.
    • (2004) Nat Rev Cancer , vol.4 , Issue.8 , pp. 592-603
    • Okada, H.1    Mak, T.W.2
  • 38
    • 57049119555 scopus 로고    scopus 로고
    • Targeting apoptosis: selected anticancer strategies
    • 10.1038/nrd2662, 19043447
    • Storey S. Targeting apoptosis: selected anticancer strategies. Nat Rev Drug Discov 2008, 7(12):971-972. 10.1038/nrd2662, 19043447.
    • (2008) Nat Rev Drug Discov , vol.7 , Issue.12 , pp. 971-972
    • Storey, S.1
  • 39
    • 44849106825 scopus 로고    scopus 로고
    • TRAIL inactivates the mitotic checkpoint and potentiates death induced by microtubule-targeting agents in human cancer cells
    • 10.1158/0008-5472.CAN-08-0014, 18451172
    • Kim M, Liao J, Dowling ML, Voong KR, Parker SE, Wang S, El-Deiry WS, Kao GD. TRAIL inactivates the mitotic checkpoint and potentiates death induced by microtubule-targeting agents in human cancer cells. Cancer Res 2008, 68(9):3440-3449. 10.1158/0008-5472.CAN-08-0014, 18451172.
    • (2008) Cancer Res , vol.68 , Issue.9 , pp. 3440-3449
    • Kim, M.1    Liao, J.2    Dowling, M.L.3    Voong, K.R.4    Parker, S.E.5    Wang, S.6    El-Deiry, W.S.7    Kao, G.D.8
  • 40
    • 2642689658 scopus 로고    scopus 로고
    • Proteases to die for
    • 10.1101/gad.12.11.1551, 9620844
    • Cryns V, Yuan J. Proteases to die for. Genes Dev 1998, 12(11):1551-1570. 10.1101/gad.12.11.1551, 9620844.
    • (1998) Genes Dev , vol.12 , Issue.11 , pp. 1551-1570
    • Cryns, V.1    Yuan, J.2
  • 41
    • 0030702084 scopus 로고    scopus 로고
    • Caspases: intracellular signaling by proteolysis
    • 10.1016/S0092-8674(00)80430-4, 9390553
    • Salvesen GS, Dixit VM. Caspases: intracellular signaling by proteolysis. Cell 1997, 91(4):443-446. 10.1016/S0092-8674(00)80430-4, 9390553.
    • (1997) Cell , vol.91 , Issue.4 , pp. 443-446
    • Salvesen, G.S.1    Dixit, V.M.2
  • 42
    • 0033861952 scopus 로고    scopus 로고
    • Death and decoy receptors and p53-mediated apoptosis
    • 10.1038/sj.leu.2401865, 10942251
    • Sheikh MS, Fornace AJ. Death and decoy receptors and p53-mediated apoptosis. Leukemia 2000, 14(8):1509-1513. 10.1038/sj.leu.2401865, 10942251.
    • (2000) Leukemia , vol.14 , Issue.8 , pp. 1509-1513
    • Sheikh, M.S.1    Fornace, A.J.2
  • 43
    • 0033974084 scopus 로고    scopus 로고
    • Molecular determinants of response to TRAIL in killing of normal and cancer cells
    • el-Deiry WS
    • Kim K, Fisher MJ, Xu SQ, . el-Deiry WS Molecular determinants of response to TRAIL in killing of normal and cancer cells. Clin Cancer Res 2000, 6(2):335-346. el-Deiry WS.
    • (2000) Clin Cancer Res , vol.6 , Issue.2 , pp. 335-346
    • Kim, K.1    Fisher, M.J.2    Xu, S.Q.3
  • 44
    • 0035863523 scopus 로고    scopus 로고
    • Pretreatment with paclitaxel enhances apo-2 ligand/tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis of prostate cancer cells by inducing death receptors 4 and 5 protein levels
    • Nimmanapalli R, Perkins CL, Orlando M, O'Bryan E, Nguyen D, Bhalla KN. Pretreatment with paclitaxel enhances apo-2 ligand/tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis of prostate cancer cells by inducing death receptors 4 and 5 protein levels. Cancer Res 2001, 61(2):759-763.
    • (2001) Cancer Res , vol.61 , Issue.2 , pp. 759-763
    • Nimmanapalli, R.1    Perkins, C.L.2    Orlando, M.3    O'Bryan, E.4    Nguyen, D.5    Bhalla, K.N.6


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