-
1
-
-
66449133280
-
Phosphorylation-driven assembly of the RIP1-RIP3 complex regulates programmed necrosis and virus-induced inflammation
-
Cho YS, Challa S, Moquin D, et al. Phosphorylation-driven assembly of the RIP1-RIP3 complex regulates programmed necrosis and virus-induced inflammation. Cell 2009; 137: 1112-1123.
-
(2009)
Cell
, vol.137
, pp. 1112-1123
-
-
Cho, Y.S.1
Challa, S.2
Moquin, D.3
-
2
-
-
0029949257
-
TNF-dependent recruitment of the protein kinase RIP to the TNF receptor-1 signaling complex
-
Hsu H, Huang J, Shu HB, Baichwal V, Goeddel DV. TNF-dependent recruitment of the protein kinase RIP to the TNF receptor-1 signaling complex. Immunity 1996; 4: 387-396.
-
(1996)
Immunity
, vol.4
, pp. 387-396
-
-
Hsu, H.1
Huang, J.2
Shu, H.B.3
Baichwal, V.4
Goeddel, D.V.5
-
3
-
-
0347065342
-
A role for tumor necrosis factor receptor-2 and receptor-interacting protein in programmed necrosis and antiviral responses
-
Chan FK, Shisler J, Bixby JG, et al. A role for tumor necrosis factor receptor-2 and receptor-interacting protein in programmed necrosis and antiviral responses. J Biol Chem 2003; 278: 51613-51621.
-
(2003)
J Biol Chem
, vol.278
, pp. 51613-51621
-
-
Chan, F.K.1
Shisler, J.2
Bixby, J.G.3
-
4
-
-
5944233768
-
Fas triggers an alternative, caspase-8-independent cell death pathway using the kinase RIP as effector molecule
-
Holler N, Zaru R, Micheau O, et al. Fas triggers an alternative, caspase-8-independent cell death pathway using the kinase RIP as effector molecule. Nat Immunol 2000; 1: 489-495.
-
(2000)
Nat Immunol
, vol.1
, pp. 489-495
-
-
Holler, N.1
Zaru, R.2
Micheau, O.3
-
5
-
-
1642299768
-
Tumor necrosis factor-induced nonapoptotic cell death requires receptor-interacting protein-mediated cellular reactive oxygen species accumulation
-
Lin Y, Choksi S, Shen HM, et al. Tumor necrosis factor-induced nonapoptotic cell death requires receptor-interacting protein-mediated cellular reactive oxygen species accumulation. J Biol Chem 2004; 279: 10822-10828.
-
(2004)
J Biol Chem
, vol.279
, pp. 10822-10828
-
-
Lin, Y.1
Choksi, S.2
Shen, H.M.3
-
6
-
-
66749183275
-
Receptor interacting protein kinase-3 determines cellular necrotic response to TNF-alpha
-
He S, Wang L, Miao L, et al. Receptor interacting protein kinase-3 determines cellular necrotic response to TNF-alpha. Cell 2009; 137: 1100-1111.
-
(2009)
Cell
, vol.137
, pp. 1100-1111
-
-
He, S.1
Wang, L.2
Miao, L.3
-
7
-
-
67650812332
-
RIP3, an energy metabolism regulator that switches TNF-induced cell death from apoptosis to necrosis
-
Zhang DW, Shao J, Lin J, et al. RIP3, an energy metabolism regulator that switches TNF-induced cell death from apoptosis to necrosis. Science 2009; 325: 332-336.
-
(2009)
Science
, vol.325
, pp. 332-336
-
-
Zhang, D.W.1
Shao, J.2
Lin, J.3
-
8
-
-
84055181328
-
Toll-like receptors activate programmed necrosis in macrophages through a receptor-interacting kinase-3-mediated pathway
-
He S, Liang Y, Shao F, Wang X. Toll-like receptors activate programmed necrosis in macrophages through a receptor-interacting kinase-3-mediated pathway. Proc Natl Acad Sci USA 2011; 108: 20054-20059.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 20054-20059
-
-
He, S.1
Liang, Y.2
Shao, F.3
Wang, X.4
-
10
-
-
0033872030
-
Cytochrome c-dependent activation of caspase-3 by tumor necrosis factor requires induction of the mitochondrial permeability transition
-
Tafani M, Schneider TG, Pastorino JG, Farber JL. Cytochrome c-dependent activation of caspase-3 by tumor necrosis factor requires induction of the mitochondrial permeability transition. Am J Pathol 2000; 156: 2111-2121.
-
(2000)
Am J Pathol
, vol.156
, pp. 2111-2121
-
-
Tafani, M.1
Schneider, T.G.2
Pastorino, J.G.3
Farber, J.L.4
-
11
-
-
28744438967
-
Ceramide mediates caspase-independent programmed cell death
-
Thon L, Mohlig H, Mathieu S, et al. Ceramide mediates caspase-independent programmed cell death. FASEB J 2005; 19: 1945-1956.
-
(2005)
FASEB J
, vol.19
, pp. 1945-1956
-
-
Thon, L.1
Mohlig, H.2
Mathieu, S.3
-
12
-
-
0032482169
-
Inhibition of caspases increases the sensitivity of L929 cells to necrosis mediated by tumor necrosis factor
-
Vercammen D, Beyaert R, Denecker G, et al. Inhibition of caspases increases the sensitivity of L929 cells to necrosis mediated by tumor necrosis factor. J Exp Med 1998; 187: 1477-1485.
-
(1998)
J Exp Med
, vol.187
, pp. 1477-1485
-
-
Vercammen, D.1
Beyaert, R.2
Denecker, G.3
-
13
-
-
0037458627
-
Disruption of HSP90 function reverts tumor necrosis factor-induced necrosis to apoptosis
-
Vanden Berghe T, Kalai M, van Loo G, Declercq W, Vandenabeele P. Disruption of HSP90 function reverts tumor necrosis factor-induced necrosis to apoptosis. J Biol Chem 2003; 278: 5622-5629.
-
(2003)
J Biol Chem
, vol.278
, pp. 5622-5629
-
-
Vanden Berghe, T.1
Kalai, M.2
van Loo, G.3
Declercq, W.4
Vandenabeele, P.5
-
14
-
-
78650175369
-
zVAD-induced necroptosis in L929 cells depends on autocrine production of TNFalpha mediated by the PKC-MAPKs-AP-1 pathway
-
Wu YT, Tan HL, Huang Q, Sun XJ, Zhu X, Shen HM. zVAD-induced necroptosis in L929 cells depends on autocrine production of TNFalpha mediated by the PKC-MAPKs-AP-1 pathway. Cell Death Differ 2010; 18: 26-37.
-
(2010)
Cell Death Differ
, vol.18
, pp. 26-37
-
-
Wu, Y.T.1
Tan, H.L.2
Huang, Q.3
Sun, X.J.4
Zhu, X.5
Shen, H.M.6
-
15
-
-
33645521571
-
Autophagic programmed cell death by selective catalase degradation
-
Yu L, Wan F, Dutta S, et al. Autophagic programmed cell death by selective catalase degradation. Proc Natl Acad Sci USA 2006; 103: 4952-4957.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 4952-4957
-
-
Yu, L.1
Wan, F.2
Dutta, S.3
-
16
-
-
79551570336
-
zVAD-induced autophagic cell death requires c-Src-dependent ERK and JNK activation and reactive oxygen species generation
-
Chen SY, Chiu LY, Maa MC, Wang JS, Chien CL, Lin WW. zVAD-induced autophagic cell death requires c-Src-dependent ERK and JNK activation and reactive oxygen species generation. Autophagy 2011; 7: 217-228.
-
(2011)
Autophagy
, vol.7
, pp. 217-228
-
-
Chen, S.Y.1
Chiu, L.Y.2
Maa, M.C.3
Wang, J.S.4
Chien, C.L.5
Lin, W.W.6
-
17
-
-
43949085388
-
Autophagy plays a protective role during zVAD-induced necrotic cell death
-
Wu YT, Tan HL, Huang Q, et al. Autophagy plays a protective role during zVAD-induced necrotic cell death. Autophagy 2008; 4: 457-466.
-
(2008)
Autophagy
, vol.4
, pp. 457-466
-
-
Wu, Y.T.1
Tan, H.L.2
Huang, Q.3
-
18
-
-
31344454770
-
The augmentation of TNFalpha-induced cell death in murine L929 fibrosarcoma by the pan-caspase inhibitor Z-VAD-fmk through pre-mitochondrial and MAPK-dependent pathways
-
Huang J, Wu L, Tashiro S, Onodera S, Ikejima T. The augmentation of TNFalpha-induced cell death in murine L929 fibrosarcoma by the pan-caspase inhibitor Z-VAD-fmk through pre-mitochondrial and MAPK-dependent pathways. Acta Med Okayama 2005; 59: 253-260.
-
(2005)
Acta Med Okayama
, vol.59
, pp. 253-260
-
-
Huang, J.1
Wu, L.2
Tashiro, S.3
Onodera, S.4
Ikejima, T.5
-
19
-
-
1842583789
-
Development by self-digestion: molecular mechanisms and biological functions of autophagy
-
Levine B, Klionsky DJ. Development by self-digestion: molecular mechanisms and biological functions of autophagy. Dev Cell 2004; 6: 463-477.
-
(2004)
Dev Cell
, vol.6
, pp. 463-477
-
-
Levine, B.1
Klionsky, D.J.2
-
20
-
-
33644840693
-
Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury
-
Degterev A, Huang Z, Boyce M, et al. Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury. Nat Chem Biol 2005; 1: 112-119.
-
(2005)
Nat Chem Biol
, vol.1
, pp. 112-119
-
-
Degterev, A.1
Huang, Z.2
Boyce, M.3
-
21
-
-
33644835625
-
Probing cell death by chemical screening
-
Wallach D. Probing cell death by chemical screening. Nat Chem Biol 2005; 1: 68-69.
-
(2005)
Nat Chem Biol
, vol.1
, pp. 68-69
-
-
Wallach, D.1
-
22
-
-
34247264421
-
Structure-activity relationship study of tricyclic necroptosis inhibitors
-
Jagtap PG, Degterev A, Choi S, Keys H, Yuan J, Cuny GD. Structure-activity relationship study of tricyclic necroptosis inhibitors. J Med Chem 2007; 50: 1886-1895.
-
(2007)
J Med Chem
, vol.50
, pp. 1886-1895
-
-
Jagtap, P.G.1
Degterev, A.2
Choi, S.3
Keys, H.4
Yuan, J.5
Cuny, G.D.6
-
23
-
-
33845926057
-
Triad3A regulates ubiquitination and proteasomal degradation of RIP1 following disruption of Hsp90 binding
-
Fearns C, Pan Q, Mathison JC, Chuang TH. Triad3A regulates ubiquitination and proteasomal degradation of RIP1 following disruption of Hsp90 binding. J Biol Chem 2006; 281: 34592-34600.
-
(2006)
J Biol Chem
, vol.281
, pp. 34592-34600
-
-
Fearns, C.1
Pan, Q.2
Mathison, J.C.3
Chuang, T.H.4
-
24
-
-
33746496627
-
The positive feedback role of arachidonic acid in the platelet-derived growth factor-induced signaling in lens epithelial cells
-
Zhang W, Wang Y, Chen CW, Xing K, Vivekanandan S, Lou MF. The positive feedback role of arachidonic acid in the platelet-derived growth factor-induced signaling in lens epithelial cells. Mol Vis 2006; 12: 821-831.
-
(2006)
Mol Vis
, vol.12
, pp. 821-831
-
-
Zhang, W.1
Wang, Y.2
Chen, C.W.3
Xing, K.4
Vivekanandan, S.5
Lou, M.F.6
-
25
-
-
33645001095
-
Butylated hydroxyanisole is more than a reactive oxygen species scavenger
-
Festjens N, Kalai M, Smet J, et al. Butylated hydroxyanisole is more than a reactive oxygen species scavenger. Cell Death Differ 2006; 13: 166-169.
-
(2006)
Cell Death Differ
, vol.13
, pp. 166-169
-
-
Festjens, N.1
Kalai, M.2
Smet, J.3
-
26
-
-
0029090167
-
Direct evidence for tumor necrosis factor-induced mitochondrial reactive oxygen intermediates and their involvement in cytotoxicity
-
Goossens V, Grooten J, De Vos K, Fiers W. Direct evidence for tumor necrosis factor-induced mitochondrial reactive oxygen intermediates and their involvement in cytotoxicity. Proc Natl Acad Sci USA 1995; 92: 8115-8119.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 8115-8119
-
-
Goossens, V.1
Grooten, J.2
De Vos, K.3
Fiers, W.4
-
27
-
-
0037944263
-
Orphan nuclear receptor Nur77 is involved in caspase-independent macrophage cell death
-
Kim SO, Ono K, Tobias PS, Han J. Orphan nuclear receptor Nur77 is involved in caspase-independent macrophage cell death. J Exp Med 2003; 197: 1441-1452.
-
(2003)
J Exp Med
, vol.197
, pp. 1441-1452
-
-
Kim, S.O.1
Ono, K.2
Tobias, P.S.3
Han, J.4
-
28
-
-
56349142515
-
Tumor necrosis factor alpha activates transcription of the NADPH oxidase organizer 1 (NOXO1) gene and upregulates superoxide production in colon epithelial cells
-
Kuwano Y, Tominaga K, Kawahara T, et al. Tumor necrosis factor alpha activates transcription of the NADPH oxidase organizer 1 (NOXO1) gene and upregulates superoxide production in colon epithelial cells. Free Radic Biol Med 2008; 45: 1642-1652.
-
(2008)
Free Radic Biol Med
, vol.45
, pp. 1642-1652
-
-
Kuwano, Y.1
Tominaga, K.2
Kawahara, T.3
-
29
-
-
34249820757
-
TNF-induced activation of the Nox1 NADPH oxidase and its role in the induction of necrotic cell death
-
Kim YS, Morgan MJ, Choksi S, Liu ZG. TNF-induced activation of the Nox1 NADPH oxidase and its role in the induction of necrotic cell death. Mol Cell 2007; 26: 675-687.
-
(2007)
Mol Cell
, vol.26
, pp. 675-687
-
-
Kim, Y.S.1
Morgan, M.J.2
Choksi, S.3
Liu, Z.G.4
-
30
-
-
33646827842
-
Poly(ADP-ribose) polymerase-1 signaling to mitochondria in necrotic cell death requires RIP1/TRAF2-mediated JNK1 activation
-
Xu Y, Huang S, Liu ZG, Han J. Poly(ADP-ribose) polymerase-1 signaling to mitochondria in necrotic cell death requires RIP1/TRAF2-mediated JNK1 activation. J Biol Chem 2006; 281: 8788-8795.
-
(2006)
J Biol Chem
, vol.281
, pp. 8788-8795
-
-
Xu, Y.1
Huang, S.2
Liu, Z.G.3
Han, J.4
-
31
-
-
57649181391
-
Identification of a molecular signaling network that regulates a cellular necrotic cell death pathway
-
Hitomi J, Christofferson DE, Ng A, Yao J, Degterev A, Xavier RJ, Yuan J. Identification of a molecular signaling network that regulates a cellular necrotic cell death pathway. Cell 2008; 135: 1311-1323.
-
(2008)
Cell
, vol.135
, pp. 1311-1323
-
-
Hitomi, J.1
Christofferson, D.E.2
Ng, A.3
Yao, J.4
Degterev, A.5
Xavier, R.J.6
Yuan, J.7
-
32
-
-
35848945069
-
Structure-activity relationship study of [1,2,3]thiadiazole necroptosis inhibitors
-
Teng X, Keys H, Jeevanandam A, et al. Structure-activity relationship study of [1, 2, 3]thiadiazole necroptosis inhibitors. Bioorg Med Chem Lett 2007; 17: 6836-6840.
-
(2007)
Bioorg Med Chem Lett
, vol.17
, pp. 6836-6840
-
-
Teng, X.1
Keys, H.2
Jeevanandam, A.3
|