Postcarotid endarterectomy improvement in cognition is associated with resolution of crossed cerebellar hypoperfusion and increase in I-Iomazenil uptake in the cerebral cortex: A SPECT study

Cerebrovascular Diseases

Volumn 29, Issue 4, 2010, Pages 343-351

  Chida, Kohei ^a   Ogasawara, Kuniaki ^a   Aso, Kenta ^a   Suga, Yasunori ^a   Kobayashi, Masakazu ^a   Yoshida, Kenji ^a   Terasaki, Kazunori ^a   Tsushina, Eiki ^b   Ogawa, Akira ^a  

^a IWATE MEDICAL UNIVERSITY   (Japan)

^b HIROSAKI UNIVERSITY   (Japan)

Author keywords

Carotid endarterectomy; Cognition; Crossed cerebellar hypoperfusion; Iomazenil

Indexed keywords

IODINE 123; IOMAZENIL; N ISOPROPYL 4 IODINE 123; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; BRAIN BLOOD FLOW; CAROTID ENDARTERECTOMY; CEREBELLUM CORTEX; COGNITION; CONTROLLED STUDY; FEMALE; HEMISPHERE; HUMAN; INTERNAL CAROTID ARTERY OCCLUSION; MAJOR CLINICAL STUDY; MALE; NEUROLOGIC EXAMINATION; PERFUSION; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; PSYCHOLOGIC TEST; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; TREATMENT OUTCOME;

ADULT; AFFERENT PATHWAYS; AGED; CAROTID ARTERY, INTERNAL; CAROTID STENOSIS; CEREBELLUM; CEREBRAL CORTEX; COGNITION DISORDERS; DOMINANCE, CEREBRAL; DOWN-REGULATION; ENDARTERECTOMY, CAROTID; FEMALE; FLUMAZENIL; HUMANS; IODINE RADIOISOTOPES; ISCHEMIA; MALE; MIDDLE AGED; NEUROPSYCHOLOGICAL TESTS; RECEPTORS, GABA-A; ROC CURVE; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON; TREATMENT OUTCOME;

EID: 75549088752     PISSN: 10159770     EISSN: None     Source Type: Journal    
DOI: 10.1159/000278930     Document Type: Article

References (32)

1. Chaturvedi S, Bruno A, Feasby T, Holloway R, Benavente O, Cohen SN, Cote R, Hess D, Saver J, Spence JD, Stern B, Wilterdink J: Carotid endarterectomy: an evidence-based review: report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology. Neurology 2005; 65: 794-801.
2. Aharon-Peretz J, Tomer R, Gabrieli I, Aharonov D, Nitecki S, Hoffman A: Cognitive performance following endarterectomy in asymptomatic severe carotid stenosis. Eur J Neurol 2003; 10: 525-528.
3. Iddon JL, Sahakian BJ, Kirkpatrick PJ: Uncomplicated carotid endarterectomy is not associated with neuropsychological impairment. Pharmacol Biochem Behav 1997; 56: 781-787.
4. Irvine CD, Gardner FV, Davies AH, Lamont PM: Cognitive testing in patients undergoing carotid endarterectomy. Eur J Vasc Endovasc Surg 1998; 15: 195-204.
5. Lunn S, Crawley F, Harrison MJ Brown MM, Newman SP: Impact of carotid endarterectomy upon cognitive functioning: a systematic review of the literature. Cerebrovasc Dis 1999; 9: 74-81.
6. Rao R: The role of carotid stenosis in vascular cognitive impairment. Eur Neurol 2001; 46: 63-69.
7. Komaba Y, Mishina M, Utsumi K, Katayama Y, Kobayashi S, Mori O: Crossed cerebellar diaschisis in patients with cortical infarction: logistic regression analysis to control for confounding effects. Stroke 2004; 35: 472-476.
8. Takasawa M, Watanabe M, Yamamoto S, Hoshi T, Sasaki T, Hashikawa K: Prognostic value of subacute crossed cerebellar diaschisis: single-photon emission CT study in patients with middle cerebral artery territory infarct. AJNR Am J Neuroradiol 2002; 23: 189-193.
9. Baron JC, Bousser MG, Comar D, Soussaline F, Castaigne P: 'Crossed cerebellar diaschisis': a remote functional suppression secondary to supratentorial infarction in man. J Cereb Blood Flow Metab 1981; 1:s500.
10. Pantano P, Baron JC, Samson Y, Bousser MG, Derouesne C, Comar D: Crossed cerebellar diaschisis: further studies. Brain 1986; 109: 677-694.
11. Serrati C, Marchal G, Rioux P, Viader F, Petit- Taboue MC, Lochon P, Luet D, Derlon JM, Baron JC: Contralateral cerebellar hypometabolism: a predictor for stroke outcome? J Neurol Neurosurg Psychiatry 1994; 57: 174-179.
12. Yamauchi H, Kudoh T, Kishibe Y, Iwasaki J, Kagawa S: Selective neuronal damage and borderzone infarction in carotid artery occlusive disease: a 11 C-flumazenil PET study. J Nucl Med 2005; 46: 1973-1979.
13. Hatazawa J, Satoh T, Shimosegawa E, Okudera T, Inugami A, Ogawa T: Evaluation of cerebral infarction with iodine 123-iomazenil SPECT. J Nucl Med 1995; 36: 2154-2161.
14. Hatazawa J, Shimosegawa E, Satoh T, Kanno I, Uemura K: Central benzodiazepine receptor distribution after subcortical hemorrhage evaluated by means of [ 123 I]iomazenil and SPECT. Stroke 1995; 26: 2267-2271.
15. Nakagawara J, Sperling B, Lassen NA: Incomplete brain infarction of reperfused cortex may be quantitated with iomazenil. Stroke 1997; 28: 124-132.
16. Millet P, Graf C, Moulin M, Ibanez V: SPECT quantification of benzodiazepine receptor concentration using a dual-ligand approach. J Nucl Med 2006; 47: 783-792.
17. Kuroda H, Ogasawara K, Aso K, Beppu T, Kobayashi M, Chida K, Ogawa A: Spontaneous recovery of reduced cortical central benzodiazepine receptor binding potential on 123 I-Iomazenil SPECT in a patient with status epileptics. Clin Nucl Med, in press.
18. Bouvard S, Costes N, Bonnefoi F, Lavenne F, Mauguière F, Delforge J, Ryvlin P: Seizurerelated short-term plasticity of benzodiazepine receptors in partial epilepsy: a [ 11 C]flumazenil-PET study. Brain 2005; 128: 1330-1343.
19. Shinagawa F, Kobayashi S, Fujita K: Japanese Wechsler Adult Intelligence Scale-Revised. Tokyo, Nihon Bunka Kagakusha, 1990.
20. Koyama M: Clinical Psychology of Brain Damage. Tokyo, Gakuen Sha, 1985, pp 48- 54.
21. Lezak MD: Neuropsychological Assessment, ed 3. New York, Oxford University Press, 1995.
22. Ogasawara K, Ito H, Sasoh M, Okuguchi, Kobayashi M, Yukawa H, Ogawa A: Quantitative measurement of regional cerebrovascular reactivity to acetazolamide using [ 123 I]iodoamphetamine autoradiographic method with single photon emission computed tomography: validation study using [ 15 O] H 2 O positron emission tomography. J Nucl Med 2006; 44: 520-525.
23. Friston KJ, Frith CD, Liddle PF, Dolan RJ, Lammertsma AA, Frackowiak RS: The relationship between global and local changes in PET scans. J Cereb Blood Flow Metab 1990; 10: 458-466.
24. Takeuchi R, Matsuda H, Yoshioka K, Yonekura Y: Cerebral blood flow SPET in transient global amnesia with automated ROI analysis by 3DSRT. Eur J Nucl Med Mol Imaging 2004; 31: 578-589.
25. Yamauchi H, Fukuyama H, Yamaguchi S, Doi T, Ogawa M, Ouchi Y, Kimura J, Sadatoh N, Yonekura Y, Tamaki N: Crossed cerebellar hypoperfusion in unilateral major cerebral artery occlusive disorders. J Nucl Med 1992; 33: 1637-1641.
26. Pappata S, Mazover B, Tran Dinh S, Cambon H, Levasseur M, Baron JC: Effects of capsular or thalamic strokes on metabolism in the cortex and cerebellum: a positron tomography study. Stroke 1990; 21: 519-524.
27. Sasoh M, Ogasawara K, Kuroda K, Okuguchi T, Terasaki K, Yamadate K, Ogawa A: Effects of EC-IC bypass surgery on cognitive impairment in patients with hemodynamic cerebral ischemia. Surg Neurol 2003; 59: 455-463.
28. Dong Y, Fukuyama H, Nabatame H, Yamauchi H, Shibasaki H, Yonekura Y: Assessment of benzodiazepine receptors using iodine- 123-labeled iomazenil single-photon emission computed tomography in patients with ischemic cerebrovascular disease. A comparison with PET study. Stroke 1997; 28: 1776-1782.
29. Heyer EJ, DeLaPaz R, Halazun HJ, Rampersad A, Sciacca R, Zurica J, Benvenisty AI, Quest DO, Todd GJ, Lavine S, Solomon RA, Connolly ES Jr: Neuropsychological dysfunction in the absence of structural evidence for cerebral ischemia after uncomplicated carotid endarterectomy. Neurosurgery 2006; 58: 474-480.
30. Mocco J, Wilson DA, Ducruet AF, Komotar RJ, Mack WJ, Zurica J, Sciacca RR, Heyer EJ, Connolly ES: Elevations in preoperative monocyte count predispose to acute neurocognitive decline after carotid endarterectomy for asymptomatic carotid artery stenosis. Stroke 2006; 37: 240-242.
31. Ogasawara K, Yamadate K, Kobayashi M, Endo H, Fukuda T, Yoshida K, Terasaki K, Inoue T, Ogawa A: Postoperative cerebral hyperperfusion associated with impaired cognitive function in patients undergoing carotid endarterectomy. J Neurosurg 2005; 102: 38-44.
32. Yamauchi H, Kudoh T, Kishibe Y, Iwasaki J, Kagawa S: Selective neuronal damage and chronic hemodynamic cerebral ischemia. Ann Neurol 2007; 61: 454-465.